Mutagenesis of coronavirus nsp14 reveals its potential role in modulation of the innate immune response

Journal of Virology

Volumn 90, Issue 11, 2016, Pages 5399-5414

  Becares, Martina ^a   Pascual Iglesias, Alejandro ^a   Nogales, Aitor ^a,b   Sola, Isabel ^a   Enjuanes, Luis ^a   Zuñiga, Sonia ^a  

^a CSIC   (Spain)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; EXORIBONUCLEASE; INTERFERON; NONSTRUCTURAL PROTEIN 14; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; ZINC FINGER PROTEIN; METHYLTRANSFERASE; VIRAL PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; BHK CELL LINE; CONTROLLED STUDY; CORONAVIRIDAE; CYTOPATHOGENIC EFFECT; ENZYME ACTIVITY; GENE MUTATION; IMMUNOMODULATION; INNATE IMMUNITY; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN SYNTHESIS; RNA SYNTHESIS; STRAIN DIFFERENCE; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIROGENESIS; VIRUS MUTANT; VIRUS RECOMBINANT; VIRUS VIABILITY; WILD TYPE; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; VIRUS REPLICATION;

CYTOPATHOGENIC EFFECT, VIRAL; EXORIBONUCLEASES; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; INTERFERON-BETA; METHYLTRANSFERASES; MUTAGENESIS; POINT MUTATION; RNA, VIRAL; TRANSMISSIBLE GASTROENTERITIS VIRUS; TUMOR NECROSIS FACTOR-ALPHA; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION; ZINC FINGERS;

EID: 84971393087     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03259-15     Document Type: Article

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