A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

PLoS Pathogens

Volumn 14, Issue 1, 2018, Pages

  Subramanian, Gayatri ^a   Kuzmanovic, Teodora ^b   Zhang, Ying ^b   Peter, Cara Beate ^a   Veleeparambil, Manoj ^b   Chakravarti, Ritu ^a   Sen, Ganes C ^b   Chattopadhyay, Saurabh ^a,b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERFERON; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RNA POLYMERASE; SHORT HAIRPIN RNA; TUDOR DOMAIN CONTAINING 7; UNCLASSIFIED DRUG; VIRAL PROTEIN; ANTIVIRUS AGENT; RIBONUCLEOPROTEIN; TDRD7 PROTEIN, MOUSE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; AUTOPHAGY; CATABOLISM; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; DNA LIBRARY; ENCEPHALOMYOCARDITIS VIRUS; ENZYME ACTIVITY; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN PARAINFLUENZA VIRUS 3; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOBLOTTING; MACROPHAGE; MTT ASSAY; NONHUMAN; PARAMYXOVIRIDAE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SENDAI VIRUS; TUDOR DOMAIN CONTAINING 7 GENE; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; IMMUNOLOGY; INNATE IMMUNITY; MOUSE; PARAMYXOVIRINAE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIVIRAL AGENTS; AUTOPHAGY; CELLS, CULTURED; GENE EXPRESSION REGULATION; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERONS; MICE; MICE, INBRED C57BL; PARAMYXOVIRINAE; RIBONUCLEOPROTEINS; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 85041510668     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006877     Document Type: Article

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