Dengue virus activates the AMP kinase-mTOR axis to stimulate a proviral lipophagy

Journal of Virology

Volumn 91, Issue 11, 2017, Pages

  Jordan, Tristan X ^a   Randall, Glenn ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Autophagy; Lipid metabolism

Indexed keywords

5' ADENOSINE MONOPHOSPHATE ACTIVATED KINASE ALPHA 1; ADENYLATE KINASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; S6 KINASE; SMALL INTERFERING RNA; TUBERIN; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; AUTOPHAGOSOME; CELLS BY BODY ANATOMY; DENGUE; DENGUE VIRUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; GENE SILENCING; HEP-G2 CELL LINE; HUMAN; IMMUNOPATHOGENESIS; INFECTED CELL; LENTIVIRINAE; LIPID METABOLISM; LIPID STORAGE; LIPOPHAGOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROVIRAL LIPOPHAGY; VIRUS CELL; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; AUTOPHAGY; DEFICIENCY; DNA REPLICATION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROVIRUS; SIGNAL TRANSDUCTION; VIRION;

ADENYLATE KINASE; AUTOPHAGY; DENGUE VIRUS; DNA REPLICATION; GENE EXPRESSION REGULATION, VIRAL; HEK293 CELLS; HEP G2 CELLS; HUMANS; LIPID METABOLISM; MULTIPROTEIN COMPLEXES; PROVIRUSES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; VIRION; VIRUS REPLICATION;

EID: 85019254450     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02020-16     Document Type: Article

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