-
1
-
-
34547188748
-
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou, L., I. I. Ivanov, R. Spolski, R. Min, K. Shenderov, T. Egawa, D. E. Levy, W. J. Leonard, and D. R. Littman. 2007. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8: 967-974.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
2
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
Weaver, C. T., R. D. Hatton, P. R. Mangan, and L. E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
3
-
-
61949463911
-
IL-17 and Th17 cells
-
Korn, T., E. Bettelli, M. Oukka, and V. K. Kuchroo. 2009. IL-17 and Th17 cells. Annu. Rev. Immunol. 27: 485-517.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
4
-
-
77950349016
-
Th17 and regulatory T cells in mediating and restraining inflammation
-
Littman, D. R., and A. Y. Rudensky. 2010. Th17 and regulatory T cells in mediating and restraining inflammation. Cell 140: 845-858.
-
(2010)
Cell
, vol.140
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
5
-
-
22444442637
-
Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor
-
Skiniotis, G., M. J. Boulanger, K. C. Garcia, and T. Walz. 2005. Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor. Nat. Struct. Mol. Biol. 12: 545-551.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 545-551
-
-
Skiniotis, G.1
Boulanger, M.J.2
Garcia, K.C.3
Walz, T.4
-
6
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga, T., and T. Kishimoto. 1997. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15: 797-819.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
7
-
-
0034658541
-
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
-
Hirano, T., K. Ishihara, and M. Hibi. 2000. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 19: 2548-2556.
-
(2000)
Oncogene
, vol.19
, pp. 2548-2556
-
-
Hirano, T.1
Ishihara, K.2
Hibi, M.3
-
8
-
-
33748588423
-
The orphan nuclear receptor RORgt directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I. I., B. S. McKenzie, L. Zhou, C. E. Tadokoro, A. Lepelley, J. J. Lafaille, D. J. Cua, and D. R. Littman. 2006. The orphan nuclear receptor RORgt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
9
-
-
0032530455
-
Tumor necrosis factor receptor-associated factors (TRAFs) - A family of adapter proteins that regulates life and death
-
Arch, R. H., R. W. Gedrich, and C. B. Thompson. 1998. Tumor necrosis factor receptor-associated factors (TRAFs)-a family of adapter proteins that regulates life and death. Genes Dev. 12: 2821-2830.
-
(1998)
Genes Dev.
, vol.12
, pp. 2821-2830
-
-
Arch, R.H.1
Gedrich, R.W.2
Thompson, C.B.3
-
10
-
-
0037084504
-
All TRAFs are not created equal: Common and distinct molecular mechanisms of TRAF-mediated signal transduction
-
Chung, J. Y., Y. C. Park, H. Ye, and H. Wu. 2002. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J. Cell Sci. 115: 679-688.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 679-688
-
-
Chung, J.Y.1
Park, Y.C.2
Ye, H.3
Wu, H.4
-
11
-
-
70549096879
-
TRAF-mediated TNFR-family signaling
-
Chapter 11: Unit 11.9D
-
Ha, H., D. Han, and Y. Choi. 2009. TRAF-mediated TNFR-family signaling. Curr. Protoc. Immunol. Chapter 11: Unit 11.9D. doi:10.1002/0471142735. im1109ds87
-
(2009)
Curr. Protoc. Immunol.
-
-
Ha, H.1
Han, D.2
Choi, Y.3
-
12
-
-
0345016454
-
TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease
-
Chiffoleau, E., T. Kobayashi, M. C. Walsh, C. G. King, P. T. Walsh, W. W. Hancock, Y. Choi, and L. A. Turka. 2003. TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease. J. Immunol. 171: 5751-5759.
-
(2003)
J. Immunol.
, vol.171
, pp. 5751-5759
-
-
Chiffoleau, E.1
Kobayashi, T.2
Walsh, M.C.3
King, C.G.4
Walsh, P.T.5
Hancock, W.W.6
Choi, Y.7
Turka, L.A.8
-
13
-
-
84935846818
-
TNF receptor-associated factor (TRAF) signaling network in CD4+ T-lymphocytes
-
So, T., H. Nagashima, and N. Ishii. 2015. TNF receptor-associated factor (TRAF) signaling network in CD4+ T-lymphocytes. Tohoku J. Exp. Med. 236: 139-154.
-
(2015)
Tohoku J. Exp. Med.
, vol.236
, pp. 139-154
-
-
So, T.1
Nagashima, H.2
Ishii, N.3
-
14
-
-
30344469074
-
TRAF1 regulates Th2 differentiation, allergic inflammation and nuclear localization of the Th2 transcription factor, NIP45
-
Bryce, P. J., M. K. Oyoshi, S. Kawamoto, H. C. Oettgen, and E. N. Tsitsikov. 2006. TRAF1 regulates Th2 differentiation, allergic inflammation and nuclear localization of the Th2 transcription factor, NIP45. Int. Immunol. 18: 101-111.
-
(2006)
Int. Immunol.
, vol.18
, pp. 101-111
-
-
Bryce, P.J.1
Oyoshi, M.K.2
Kawamoto, S.3
Oettgen, H.C.4
Tsitsikov, E.N.5
-
15
-
-
77954696814
-
TRAF6 inhibits Th17 differentiation and TGFbeta-mediated suppression of IL-2
-
Cejas, P. J., M. C. Walsh, E. L. Pearce, D. Han, G. M. Harms, D. Artis, L. A. Turka, and Y. Choi. 2010. TRAF6 inhibits Th17 differentiation and TGFbeta-mediated suppression of IL-2. Blood 115: 4750-4757.
-
(2010)
Blood
, vol.115
, pp. 4750-4757
-
-
Cejas, P.J.1
Walsh, M.C.2
Pearce, E.L.3
Han, D.4
Harms, G.M.5
Artis, D.6
Turka, L.A.7
Choi, Y.8
-
16
-
-
84866552162
-
H9 cells and airway inflammation
-
H9 cells and airway inflammation. Nat. Immunol. 13: 981-990.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 981-990
-
-
Xiao, X.1
Balasubramanian, S.2
Liu, W.3
Chu, X.4
Wang, H.5
Taparowsky, E.J.6
Fu, Y.X.7
Choi, Y.8
Walsh, M.C.9
Li, X.C.10
-
17
-
-
84906310292
-
The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2
-
Yi, Z., W. W. Lin, L. L. Stunz, and G. A. Bishop. 2014. The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2. Nat. Immunol. 15: 866-874.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 866-874
-
-
Yi, Z.1
Lin, W.W.2
Stunz, L.L.3
Bishop, G.A.4
-
18
-
-
84899477789
-
+ T cells by antagonizing signaling via the receptor for IL-6
-
+ T cells by antagonizing signaling via the receptor for IL-6. Nat. Immunol. 15: 449-456.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 449-456
-
-
Nagashima, H.1
Okuyama, Y.2
Asao, A.3
Kawabe, T.4
Yamaki, S.5
Nakano, H.6
Croft, M.7
Ishii, N.8
So, T.9
-
19
-
-
1642331575
-
TNF receptor-associated factor 5 limits the induction of Th2 immune responses
-
So, T., S. Salek-Ardakani, H. Nakano, C. F. Ware, and M. Croft. 2004. TNF receptor-associated factor 5 limits the induction of Th2 immune responses. J. Immunol. 172: 4292-4297.
-
(2004)
J. Immunol.
, vol.172
, pp. 4292-4297
-
-
So, T.1
Salek-Ardakani, S.2
Nakano, H.3
Ware, C.F.4
Croft, M.5
-
20
-
-
0031962348
-
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κb
-
Arch, R. H., and C. B. Thompson. 1998. 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor κB. Mol. Cell. Biol. 18: 558-565.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 558-565
-
-
Arch, R.H.1
Thompson, C.B.2
-
21
-
-
0001033803
-
Structural basis for self-association and receptor recognition of human TRAF2
-
Park, Y. C., V. Burkitt, A. R. Villa, L. Tong, and H. Wu. 1999. Structural basis for self-association and receptor recognition of human TRAF2. Nature 398: 533-538.
-
(1999)
Nature
, vol.398
, pp. 533-538
-
-
Park, Y.C.1
Burkitt, V.2
Villa, A.R.3
Tong, L.4
Wu, H.5
-
22
-
-
0033197872
-
The structural basis for the recognition of diverse receptor sequences by TRAF2
-
Ye, H., Y. C. Park, M. Kreishman, E. Kieff, and H. Wu. 1999. The structural basis for the recognition of diverse receptor sequences by TRAF2. Mol. Cell 4: 321-330.
-
(1999)
Mol. Cell
, vol.4
, pp. 321-330
-
-
Ye, H.1
Park, Y.C.2
Kreishman, M.3
Kieff, E.4
Wu, H.5
-
23
-
-
1542514775
-
Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells
-
Takeda, I., S. Ine, N. Killeen, L. C. Ndhlovu, K. Murata, S. Satomi, K. Sugamura, and N. Ishii. 2004. Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells. J. Immunol. 172: 3580-3589.
-
(2004)
J. Immunol.
, vol.172
, pp. 3580-3589
-
-
Takeda, I.1
Ine, S.2
Killeen, N.3
Ndhlovu, L.C.4
Murata, K.5
Satomi, S.6
Sugamura, K.7
Ishii, N.8
-
24
-
-
0034046944
-
Plat-E: An efficient and stable system for transient packaging of retroviruses
-
Morita, S., T. Kojima, and T. Kitamura. 2000. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7: 1063-1066.
-
(2000)
Gene Ther.
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
-
25
-
-
0142227052
-
Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics
-
Kitamura, T., Y. Koshino, F. Shibata, T. Oki, H. Nakajima, T. Nosaka, and H. Kumagai. 2003. Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp. Hematol. 31: 1007-1014.
-
(2003)
Exp. Hematol.
, vol.31
, pp. 1007-1014
-
-
Kitamura, T.1
Koshino, Y.2
Shibata, F.3
Oki, T.4
Nakajima, H.5
Nosaka, T.6
Kumagai, H.7
-
26
-
-
33747608638
-
NF-κBdependent induction of microRNA MIR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov, K. D., M. P. Boldin, K. J. Chang, and D. Baltimore. 2006. NF-κBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. USA 103: 12481-12486.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
27
-
-
84863982248
-
Integration of BRCA1-mediated miRNA and mRNA profiles reveals microRNA regulation of TRAF2 and NFκB pathway
-
Tanic, M., M. Zajac, G. Gómez-López, J. Benítez, and B. Martínez-Delgado. 2012. Integration of BRCA1-mediated miRNA and mRNA profiles reveals microRNA regulation of TRAF2 and NFκB pathway. Breast Cancer Res. Treat. 134: 41-51.
-
(2012)
Breast Cancer Res. Treat.
, vol.134
, pp. 41-51
-
-
Tanic, M.1
Zajac, M.2
Gómez-López, G.3
Benítez, J.4
Martínez-Delgado, B.5
-
28
-
-
84898657121
-
Suppressive role of MIR-502-5p in breast cancer via downregulation of TRAF2
-
Sun, L. L., J.Wang, Z. J. Zhao, N. Liu, A. L.Wang, H. Y. Ren, F. Yang, K. X. Diao, W. N. Fu, E. H.Wan, and X. Y. Mi. 2014. Suppressive role of miR-502-5p in breast cancer via downregulation of TRAF2. Oncol. Rep. 31: 2085-2092.
-
(2014)
Oncol. Rep.
, vol.31
, pp. 2085-2092
-
-
Sun, L.L.1
Wang, J.2
Zhao, Z.J.3
Liu, N.4
Wang, A.L.5
Ren, H.Y.6
Yang, F.7
Diao, K.X.8
Fu, W.N.9
Wan, E.H.10
Mi, X.Y.11
-
29
-
-
84924506715
-
The MIR-322-TRAF3 circuit mediates the pro-apoptotic effect of high glucose on neural stem cells
-
Gu, H., J. Yu, D. Dong, Q. Zhou, J. Y. Wang, and P. Yang. 2015. The miR-322-TRAF3 circuit mediates the pro-apoptotic effect of high glucose on neural stem cells. Toxicol. Sci. 144: 186-196.
-
(2015)
Toxicol. Sci.
, vol.144
, pp. 186-196
-
-
Gu, H.1
Yu, J.2
Dong, D.3
Zhou, Q.4
Wang, J.Y.5
Yang, P.6
-
30
-
-
5044223172
-
The multifaceted roles of TRAFs in the regulation of B-cell function
-
Bishop, G. A. 2004. The multifaceted roles of TRAFs in the regulation of B-cell function. Nat. Rev. Immunol. 4: 775-786.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 775-786
-
-
Bishop, G.A.1
-
31
-
-
84876667044
-
A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation
-
Chen, B. B., T. A. Coon, J. R. Glasser, B. J. McVerry, J. Zhao, Y. Zhao, C. Zou, B. Ellis, F. C. Sciurba, Y. Zhang, and R. K. Mallampalli. 2013. A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation. Nat. Immunol. 14: 470-479.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 470-479
-
-
Chen, B.B.1
Coon, T.A.2
Glasser, J.R.3
McVerry, B.J.4
Zhao, J.5
Zhao, Y.6
Zou, C.7
Ellis, B.8
Sciurba, F.C.9
Zhang, Y.10
Mallampalli, R.K.11
-
32
-
-
84931068090
-
Targeting signaling factors for degradation, an emerging mechanism for TRAF functions
-
Yang, X. D., and S. C. Sun. 2015. Targeting signaling factors for degradation, an emerging mechanism for TRAF functions. Immunol. Rev. 266: 56-71.
-
(2015)
Immunol. Rev.
, vol.266
, pp. 56-71
-
-
Yang, X.D.1
Sun, S.C.2
-
33
-
-
0031903792
-
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation
-
Betz, U. A., and W. Müller. 1998. Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation. Int. Immunol. 10: 1175-1184.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1175-1184
-
-
Betz, U.A.1
Müller, W.2
-
34
-
-
69249223474
-
Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK
-
Jin, W., X. F. Zhou, J. Yu, X. Cheng, and S. C. Sun. 2009. Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK. Blood 113: 6603-6610.
-
(2009)
Blood
, vol.113
, pp. 6603-6610
-
-
Jin, W.1
Zhou, X.F.2
Yu, J.3
Cheng, X.4
Sun, S.C.5
-
35
-
-
40249115896
-
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor
-
Gardam, S., F. Sierro, A. Basten, F. Mackay, and R. Brink. 2008. TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity 28: 391-401.
-
(2008)
Immunity
, vol.28
, pp. 391-401
-
-
Gardam, S.1
Sierro, F.2
Basten, A.3
Mackay, F.4
Brink, R.5
-
36
-
-
81055145273
-
Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity
-
Lin, W. J., Y. W. Su, Y. C. Lu, Z. Hao, I. I. Chio, N. J. Chen, A. Brüstle, W. Y. Li, and T. W. Mak. 2011. Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity. Proc. Natl. Acad. Sci. USA 108: 18354-18359.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 18354-18359
-
-
Lin, W.J.1
Su, Y.W.2
Lu, Y.C.3
Hao, Z.4
Chio, I.I.5
Chen, N.J.6
Brüstle, A.7
Li, W.Y.8
Mak, T.W.9
|