Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Gilsbach, Ralf ^a   Schwaderer, Martin ^a   Preissl, Sebastian ^a   Grüning, Björn A ^b   Kranzhöfer, David ^a   Schneider, Pedro ^a   Nührenberg, Thomas G ^a,c   Mulero Navarro, Sonia ^d   Weichenhan, Dieter ^e   Braun, Christian ^f   Dreßen, Martina ^g   Jacobs, Adam R ^d   Lahm, Harald ^g   Doenst, Torsten ^h   Backofen, Rolf ^b   Krane, Markus ^g,i   Gelb, Bruce D ^d   Hein, Lutz ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

^g TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^h JENA UNIVERSITY HOSPITAL   (Germany)

ⁱ DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CONNECTIVE TISSUE GROWTH FACTOR; HISTONE; MYOCYTE ENHANCER FACTOR 2; MYOSIN HEAVY CHAIN ALPHA; MYOSIN HEAVY CHAIN BETA; NATRIURETIC FACTOR; NATRIURETIC PEPTIDE A; NATRIURETIC PEPTIDE B; NUCLEIC ACID BINDING PROTEIN; PHOSPHOLAMBAN; PLAKOPHILIN; T BOX TRANSCRIPTION FACTOR; TGGCA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTCF; TRANSCRIPTION FACTOR GATA; TRANSCRIPTION FACTOR TEAD; TRANSCRIPTOME; TROPONIN; TROPONIN I1; TROPONIN T2; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

BIOLOGICAL DEVELOPMENT; CARDIOVASCULAR SYSTEM; CELL; GENE EXPRESSION; GENETICS; LABORATORY METHOD; MATURATION; METHYLATION; PROTEIN;

ADULT; ARTICLE; CARDIAC MUSCLE CELL; CARDIOVASCULAR DISEASE; CONGENITAL HEART DISEASE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENHANCER REGION; EPIGENETICS; FETUS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MAPPING; GENE ONTOLOGY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HEART ARRHYTHMIA; HEART DEVELOPMENT; HEART FAILURE; HEART INFARCTION; HEART TISSUE; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INFANT; ISCHEMIC HEART DISEASE; MALE; POSTNATAL DEVELOPMENT; PRENATAL DEVELOPMENT; PROMOTER REGION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTOMICS; CELL DIFFERENTIATION; CHROMATIN; GENETIC EPIGENESIS; GENETICS; METABOLISM; PHYSIOLOGY;

CARDIOVASCULAR DISEASES; CELL DIFFERENTIATION; CHROMATIN; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; HEART FAILURE; HUMANS; MYOCYTES, CARDIAC;

EID: 85041208966     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02762-z     Document Type: Article

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