Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1863, Issue 7, 2016, Pages 1772-1781

  Han, Pei ^a,b   Li, Wei ^a,b   Yang, Jin ^a   Shang, Ching ^a,b   Lin, Chiou Hong ^b   Cheng, Wei ^a   Hang, Calvin T ^a,b   Cheng, Hsiu Ling ^b   Chen, Chen Hao ^b   Wong, Johnson ^e   Xiong, Yiqin ^b   Zhao, Mingming ^b   Drakos, Stavros G ^c   Ghetti, Andrea ^d   Li, Dean Y ^c   Bernstein, Daniel ^b   Chen, Huei sheng Vincent ^e   Quertermous, Thomas ^b   Chang, Ching Pin ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INTERMOUNTAIN MEDICAL CENTER   (United States)

^d ANABIOS CORPORATION   (United States)

^e BURNHAM INSTITUTE   (United States)

Author keywords

Brg1; Cardiac hypertrophy; Cardiomyopathy; Chromatin remodeling; DNA methylation; Dnmt; G9a; Gene silencing; H3K9me2; Heart failure; Histone methylation; Myosin heavy chain

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; BRG1 PROTEIN; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DOXYCYCLINE; HISTONE METHYLTRANSFERASE; MOLECULAR MOTOR; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN 6; MYOSIN HEAVY CHAIN 7; UNCLASSIFIED DRUG; CHROMATIN; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA HELICASE; G9A PROTEIN, MOUSE; GLP PROTEIN, MOUSE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; MYH6 PROTEIN, MOUSE; NUCLEAR PROTEIN; PROTEIN BINDING; SMARCA4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

5' UNTRANSLATED REGION; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE; CARDIOMYOPATHY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ECHOCARDIOGRAPHY; ENVIRONMENTAL STRESS; EPIGENETICS; FETUS; FETUS HEART; GENE SILENCING; HEART CONTRACTION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE; HEART STRESS; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; HISTONE METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; TAKOTSUBO CARDIOMYOPATHY; ADAPTATION; ANIMAL; CARDIOMEGALY; CHROMATIN; CONVALESCENCE; DEFICIENCY; DISEASE MODEL; ENZYMOLOGY; GENETIC EPIGENESIS; GENETICS; GESTATIONAL AGE; HEART LEFT VENTRICLE FUNCTION; HUMAN; KNOCKOUT MOUSE; METABOLISM; METHYLATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CARDIOMEGALY; CARDIOMYOPATHIES; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CPG ISLANDS; DISEASE MODELS, ANIMAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA HELICASES; DNA METHYLATION; EPIGENESIS, GENETIC; GESTATIONAL AGE; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; METHYLATION; MICE, KNOCKOUT; MYOCARDIUM; MYOSIN HEAVY CHAINS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 84962077711     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2016.03.002     Document Type: Article

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