-
1
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA, 1000. Genomes Project Consortium. 2010. A map of human genome variation from population-scale sequencing. Nature 467: 1061–1073. doi: 10.1038/nature09534.
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
Abecasis, G.R.1
Altshuler, D.2
Auton, A.3
Brooks, L.D.4
Durbin, R.M.5
Gibbs, R.A.6
Hurles, M.E.7
McVean, G.A.8
-
2
-
-
55449120805
-
Genetic mapping in human disease
-
Altshuler D, Daly MJ, Lander ES. 2008. Genetic mapping in human disease. Science 322:881–888. doi: 10.1126/science.1156409.
-
(2008)
Science
, vol.322
, pp. 881-888
-
-
Altshuler, D.1
Daly, M.J.2
Lander, E.S.3
-
3
-
-
84897459814
-
An atlas of active enhancers across human cell types and tissues
-
Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E, Valen E, Li K, Schwarzfischer L, Glatz D, Raithel J, Lilje B, Rapin N, Bagger FO, et al. 2014. An atlas of active enhancers across human cell types and tissues. Nature 507:455–461. doi: 10.1038/nature12787.
-
(2014)
Nature
, vol.507
, pp. 455-461
-
-
Andersson, R.1
Gebhard, C.2
Miguel-Escalada, I.3
Hoof, I.4
Bornholdt, J.5
Boyd, M.6
Chen, Y.7
Zhao, X.8
Schmidl, C.9
Suzuki, T.10
Ntini, E.11
Arner, E.12
Valen, E.13
Li, K.14
Schwarzfischer, L.15
Glatz, D.16
Raithel, J.17
Lilje, B.18
Rapin, N.19
Bagger, F.O.20
more..
-
4
-
-
84905594041
-
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
-
Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, et al. 2014. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics 46:826–836. doi: 10.1038/ng.3014.
-
(2014)
Nature Genetics
, vol.46
, pp. 826-836
-
-
Arking, D.E.1
Pulit, S.L.2
Crotti, L.3
Van Der Harst, P.4
Munroe, P.B.5
Koopmann, T.T.6
Sotoodehnia, N.7
Rossin, E.J.8
Morley, M.9
Wang, X.10
Johnson, A.D.11
Lundby, A.12
Gudbjartsson, D.F.13
Noseworthy, P.A.14
Eijgelsheim, M.15
Bradford, Y.16
Tarasov, K.V.17
Dörr, M.18
Müller-Nurasyid, M.19
Lahtinen, A.M.20
more..
-
5
-
-
84863543347
-
Tbx5 drives scn5a expression to regulate cardiac conduction system function
-
Arnolds DE, Liu F, Fahrenbach JP, Kim GH, Schillinger KJ, Smemo S, McNally EM, Nobrega MA, Patel VV, Moskowitz IP. 2012. Tbx5 drives scn5a expression to regulate cardiac conduction system function. The Journal of Clinical Investigation 122:2509–2518. doi: 10.1172/JCI62617.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, pp. 2509-2518
-
-
Arnolds, D.E.1
Liu, F.2
Fahrenbach, J.P.3
Kim, G.H.4
Schillinger, K.J.5
Smemo, S.6
McNally, E.M.7
Nobrega, M.A.8
Patel, V.V.9
Moskowitz, I.P.10
-
6
-
-
84939240528
-
Allele, phenotype and disease data at mouse genome informatics: Improving access and analysis
-
Bello SM, Smith CL, Eppig JT. 2015. Allele, phenotype and disease data at mouse genome informatics: Improving access and analysis. Mammalian Genome 26:285–294. doi: 10.1007/s00335-015-9582-y
-
(2015)
Mammalian Genome
, vol.26
, pp. 285-294
-
-
Bello, S.M.1
Smith, C.L.2
Eppig, J.T.3
-
7
-
-
84868198825
-
Breast cancer risk-associated snps modulate the affinity of chromatin for FOXA1 and alter gene expression
-
Cowper-Sal lari R, Zhang X, Wright JB, Bailey SD, Cole MD, Eeckhoute J, Moore JH, Lupien M. 2012. Breast cancer risk-associated snps modulate the affinity of chromatin for FOXA1 and alter gene expression. Nature Genetics 44:1191–1198. doi: 10.1038/ng.2416.
-
(2012)
Nature Genetics
, vol.44
, pp. 1191-1198
-
-
Cowper-Sal Lari, R.1
Zhang, X.2
Wright, J.B.3
Bailey, S.D.4
Cole, M.D.5
Eeckhoute, J.6
Moore, J.H.7
Lupien, M.8
-
8
-
-
78650758676
-
Histone h3k27ac separates active from poised enhancers and predicts developmental state
-
Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. 2010. Histone h3k27ac separates active from poised enhancers and predicts developmental state. Proceedings of the National Academy of Sciences of the United States of America 107:21931–21936. doi: 10.1073/pnas.1016071107.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
Carey, B.W.5
Steine, E.J.6
Hanna, J.7
Lodato, M.A.8
Frampton, G.M.9
Sharp, P.A.10
Boyer, L.A.11
Young, R.A.12
Jaenisch, R.13
-
9
-
-
82355175128
-
NKX2-5(EGEP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes
-
Elliott DA, Braam SR, Koutsis K, Ng ES, Jenny R, Lagerqvist EL, Biben C, Hatzistavrou T, Hirst CE, Yu QC, Skelton RJ, Ward-van Oostwaard D, Lim SM, Khammy O, Li X, Hawes SM, Davis RP, Goulburn AL, Passier R, Prall OW, et al. 2011. NKX2-5(eGEP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nature Methods 8:1037–1040. doi: 10.1038/nmeth.1740.
-
(2011)
Nature Methods
, vol.8
, pp. 1037-1040
-
-
Elliott, D.A.1
Braam, S.R.2
Koutsis, K.3
Ng, E.S.4
Jenny, R.5
Lagerqvist, E.L.6
Biben, C.7
Hatzistavrou, T.8
Hirst, C.E.9
Yu, Q.C.10
Skelton, R.J.11
Ward-Van Oostwaard, D.12
Lim, S.M.13
Khammy, O.14
Li, X.15
Hawes, S.M.16
Davis, R.P.17
Goulburn, A.L.18
Passier, R.19
Prall, O.W.20
more..
-
10
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57–74. doi: 10.1038/nature11247.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
11
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE. 2011. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473:43–49. doi: 10.1038/nature09906.
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
Ward, L.D.5
Epstein, C.B.6
Zhang, X.7
Wang, L.8
Issner, R.9
Coyne, M.10
Ku, M.11
Durham, T.12
Kellis, M.13
Bernstein, B.E.14
-
12
-
-
85000443086
-
Partitioning heritability by functional annotation using genome-wide association summary statistics
-
Finucane HK, Bulik-Sullivan B, Gusev A, Trynka G, Reshef Y, Loh PR, Anttila V, Xu H, Zang C, Farh K, Ripke S, Day FR, Purcell S, Stahl E, Lindstrom S, Perry JR, Okada Y, Raychaudhuri S, Daly MJ, Patterson N, et al. 2015. Partitioning heritability by functional annotation using genome-wide association summary statistics. Nature Genetics 47:1228–1235. doi: 10.1038/ng.3404.
-
(2015)
Nature Genetics
, vol.47
, pp. 1228-1235
-
-
Finucane, H.K.1
Bulik-Sullivan, B.2
Gusev, A.3
Trynka, G.4
Reshef, Y.5
Loh, P.R.6
Anttila, V.7
Xu, H.8
Zang, C.9
Farh, K.10
Ripke, S.11
Day, F.R.12
Purcell, S.13
Stahl, E.14
Lindstrom, S.15
Perry, J.R.16
Okada, Y.17
Raychaudhuri, S.18
Daly, M.J.19
Patterson, N.20
more..
-
13
-
-
34347244234
-
Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish
-
Fisher S, Grice EA, Vinton RM, Bessling SL, Urasaki A, Kawakami K, McCallion AS. 2006. Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish. Nature Protocols 1: 1297–1305. doi: 10.1038/nprot.2006.230.
-
(2006)
Nature Protocols
, vol.1
, pp. 1297-1305
-
-
Fisher, S.1
Grice, E.A.2
Vinton, R.M.3
Bessling, S.L.4
Urasaki, A.5
Kawakami, K.6
McCallion, A.S.7
-
14
-
-
84857119014
-
Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
-
Froese A, Breher SS, Waldeyer C, Schindler RF, Nikolaev VO, Rinne´ S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, Liebig SK, Laakmann S, Müller TD, Neumann J, Stieber J, et al. 2012. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. The Journal of Clinical Investigation 122:1119–1130. doi: 10.1172/JCI59410.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, pp. 1119-1130
-
-
Froese, A.1
Breher, S.S.2
Waldeyer, C.3
Schindler, R.F.4
Nikolaev, V.O.5
Rinne´, S.6
Wischmeyer, E.7
Schlueter, J.8
Becher, J.9
Simrick, S.10
Vauti, F.11
Kuhtz, J.12
Meister, P.13
Kreissl, S.14
Torlopp, A.15
Liebig, S.K.16
Laakmann, S.17
Müller, T.D.18
Neumann, J.19
Stieber, J.20
more..
-
15
-
-
70449103609
-
An oestrogen- receptor-alpha-bound human chromatin interactome
-
Fullwood MJ, Liu MH, Pan YF, Liu J, Xu H, Mohamed YB, Orlov YL, Velkov S, Ho A, Mei PH, Chew EG, Huang PY, Welboren WJ, Han Y, Ooi HS, Ariyaratne PN, Vega VB, Luo Y, Tan PY, Choy PY, et al. 2009. An oestrogen- receptor-alpha-bound human chromatin interactome. Nature 462:58–64. doi: 10.1038/nature08497.
-
(2009)
Nature
, vol.462
, pp. 58-64
-
-
Fullwood, M.J.1
Liu, M.H.2
Pan, Y.F.3
Liu, J.4
Xu, H.5
Mohamed, Y.B.6
Orlov, Y.L.7
Velkov, S.8
Ho, A.9
Mei, P.H.10
Chew, E.G.11
Huang, P.Y.12
Welboren, W.J.13
Han, Y.14
Ooi, H.S.15
Ariyaratne, P.N.16
Vega, V.B.17
Luo, Y.18
Tan, P.Y.19
Choy, P.Y.20
more..
-
16
-
-
84923377359
-
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
-
Gjoneska E, Pfenning AR, Mathys H, Quon G, Kundaje A, Tsai LH, Kellis M. 2015. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease. Nature 518:365–369. doi: 10.1038/nature14252.
-
(2015)
Nature
, vol.518
, pp. 365-369
-
-
Gjoneska, E.1
Pfenning, A.R.2
Mathys, H.3
Quon, G.4
Kundaje, A.5
Tsai, L.H.6
Kellis, M.7
-
17
-
-
84922273141
-
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
-
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, et al. 2014. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. American Journal of Human Genetics 95:535–552. doi: 10.1016/j.ajhg.2014.10.004.
-
(2014)
American Journal of Human Genetics
, vol.95
, pp. 535-552
-
-
Gusev, A.1
Lee, S.H.2
Trynka, G.3
Finucane, H.4
Vilhjálmsson, B.J.5
Xu, H.6
Zang, C.7
Ripke, S.8
Bulik-Sullivan, B.9
Stahl, E.10
Kähler, A.K.11
Hultman, C.M.12
Purcell, S.M.13
McCarroll, S.A.14
Daly, M.15
Pasaniuc, B.16
Sullivan, P.F.17
Neale, B.M.18
Wray, N.R.19
Raychaudhuri, S.20
more..
-
18
-
-
84865760395
-
Gencode: The reference human genome annotation for the ENCODE project
-
Harrow J, Frankish A, Gonzalez JM, Tapanari E, Diekhans M, Kokocinski F, Aken BL, Barrell D, Zadissa A, Searle S, Barnes I, Bignell A, Boychenko V, Hunt T, Kay M, Mukherjee G, Rajan J, Despacio-Reyes G, Saunders G, Steward C, et al. 2012. Gencode: The reference human genome annotation for the ENCODE project. Genome Research 22:1760–1774. doi: 10.1101/gr.135350.111.
-
(2012)
Genome Research
, vol.22
, pp. 1760-1774
-
-
Harrow, J.1
Frankish, A.2
Gonzalez, J.M.3
Tapanari, E.4
Diekhans, M.5
Kokocinski, F.6
Aken, B.L.7
Barrell, D.8
Zadissa, A.9
Searle, S.10
Barnes, I.11
Bignell, A.12
Boychenko, V.13
Hunt, T.14
Kay, M.15
Mukherjee, G.16
Rajan, J.17
Despacio-Reyes, G.18
Saunders, G.19
Steward, C.20
more..
-
19
-
-
77958500384
-
Drug-induced arrhythmia
-
Heist EK, Ruskin JN, 1000. Genomes Project Consortium. 2010. Drug-induced arrhythmia. Circulation 122:1426–1435. doi: 10.1161/CIRCULATIONAHA.109.894725.
-
(2010)
Circulation
, vol.122
, pp. 1426-1435
-
-
Heist, E.K.1
Ruskin, J.N.2
-
20
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. 2009. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America 106:9362–9367. doi: 10.1073/pnas.0903103106.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
21
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-André V, Sigova AA, Hoke HA, Young RA. 2013. Super-enhancers in the control of cell identity and disease. Cell 155:934–947. doi: 10.1016/j.cell.2013.09.053.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Saint-André, V.5
Sigova, A.A.6
Hoke, H.A.7
Young, R.A.8
-
22
-
-
84885021247
-
Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues
-
Hon GC, Rajagopal N, Shen Y, McCleary DF, Yue F, Dang MD, Ren B. 2013. Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nature Genetics 45:1198–1206. doi: 10.1038/ng.2746.
-
(2013)
Nature Genetics
, vol.45
, pp. 1198-1206
-
-
Hon, G.C.1
Rajagopal, N.2
Shen, Y.3
McCleary, D.F.4
Yue, F.5
Dang, M.D.6
Ren, B.7
-
23
-
-
84857117777
-
The popeye domain containing 2 (Popdc2) gene in zebrafish is required for heart and skeletal muscle development
-
Kirchmaier BC, Poon KL, Schwerte T, Huisken J, Winkler C, Jungblut B, Stainier DY, Brand T. 2012. The popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development. Developmental Biology 363:438–450. doi: 10.1016/j.ydbio.2012.01.015.
-
(2012)
Developmental Biology
, vol.363
, pp. 438-450
-
-
Kirchmaier, B.C.1
Poon, K.L.2
Schwerte, T.3
Huisken, J.4
Winkler, C.5
Jungblut, B.6
Stainier, D.Y.7
Brand, T.8
-
24
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
-
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, et al. 2013. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nature Genetics 45:1452–1458. doi: 10.1038/ng.2802.
-
(2013)
Nature Genetics
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
Destafano, A.L.7
Bis, J.C.8
Beecham, G.W.9
Grenier-Boley, B.10
Russo, G.11
Thorton-Wells, T.A.12
Jones, N.13
Smith, A.V.14
Chouraki, V.15
Thomas, C.16
Ikram, M.A.17
Zelenika, D.18
Vardarajan, B.N.19
Kamatani, Y.20
more..
-
25
-
-
55549147191
-
Personal genomes: The case of the missing heritability
-
Maher B. 2008. Personal genomes: The case of the missing heritability. Nature 456:18–21. doi: 10.1038/456018a
-
(2008)
Nature
, vol.456
, pp. 18-21
-
-
Maher, B.1
-
26
-
-
70450171127
-
Isotone optimization in R: Pool-adjacent-violators algorithm (PAVA) and active set methods
-
Mair P, Hornik K, de Leeuw J. 2009. Isotone optimization in R: Pool-adjacent-violators algorithm (PAVA) and active set methods. Journal of Statistical Software 32:1–24.
-
(2009)
Journal of Statistical Software
, vol.32
, pp. 1-24
-
-
Mair, P.1
Hornik, K.2
De Leeuw, J.3
-
27
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehling-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, et al. 2012. Systematic localization of common disease-associated variation in regulatory DNA. Science 337:1190–1195. doi: 10.1126/science.1222794.
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
Wang, H.6
Reynolds, A.P.7
Sandstrom, R.8
Qu, H.9
Brody, J.10
Shafer, A.11
Neri, F.12
Lee, K.13
Kutyavin, T.14
Stehling-Sun, S.15
Johnson, A.K.16
Canfield, T.K.17
Giste, E.18
Diegel, M.19
Bates, D.20
more..
-
28
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, et al. 2010. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466:714–719. doi: 10.1038/nature09266.
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
Lee, N.E.4
Ahfeldt, T.5
Sachs, K.V.6
Li, X.7
Li, H.8
Kuperwasser, N.9
Ruda, V.M.10
Pirruccello, J.P.11
Muchmore, B.12
Prokunina-Olsson, L.13
Hall, J.L.14
Schadt, E.E.15
Morales, C.R.16
Lund-Katz, S.17
Phillips, M.C.18
Wong, J.19
Cantley, W.20
more..
-
29
-
-
84866361701
-
Circuitry and dynamics of human transcription factor regulatory networks
-
Neph S, Stergachis AB, Reynolds A, Sandstrom R, Borenstein E, Stamatoyannopoulos JA. 2012. Circuitry and dynamics of human transcription factor regulatory networks. Cell 150:1274–1286. doi: 10.1016/j.cell.2012.04.040.
-
(2012)
Cell
, vol.150
, pp. 1274-1286
-
-
Neph, S.1
Stergachis, A.B.2
Reynolds, A.3
Sandstrom, R.4
Borenstein, E.5
Stamatoyannopoulos, J.A.6
-
30
-
-
84894598129
-
Rapid and pervasive changes in genome-wide enhancer usage during mammalian development
-
Nord AS, Blow MJ, Attanasio C, Akiyama JA, Holt A, Hosseini R, Phouanenavong S, Plajzer-Frick I, Shoukry M, Afzal V, Rubenstein JL, Rubin EM, Pennacchio LA, Visel A. 2013. Rapid and pervasive changes in genome-wide enhancer usage during mammalian development. Cell 155:1521–1531. doi: 10.1016/j.cell.2013.11.033.
-
(2013)
Cell
, vol.155
, pp. 1521-1531
-
-
Nord, A.S.1
Blow, M.J.2
Attanasio, C.3
Akiyama, J.A.4
Holt, A.5
Hosseini, R.6
Phouanenavong, S.7
Plajzer-Frick, I.8
Shoukry, M.9
Afzal, V.10
Rubenstein, J.L.11
Rubin, E.M.12
Pennacchio, L.A.13
Visel, A.14
-
31
-
-
77951770756
-
Bedtools: A flexible suite of utilities for comparing genomic features
-
Quinlan AR, Hall IM. 2010. Bedtools: A flexible suite of utilities for comparing genomic features. Bioinformatics 26:841–842. doi: 10.1093/bioinformatics/btq033.
-
(2010)
Bioinformatics
, vol.26
, pp. 841-842
-
-
Quinlan, A.R.1
Hall, I.M.2
-
32
-
-
0020031115
-
The electrocardiogram in apparently healthy men and the risk of sudden death
-
Rabkin SW, Mathewson FL, Tate RB. 1982. The electrocardiogram in apparently healthy men and the risk of sudden death. Heart 47:546–552. doi: 10.1136/hrt.47.6.546.
-
(1982)
Heart
, vol.47
, pp. 546-552
-
-
Rabkin, S.W.1
Mathewson, F.L.2
Tate, R.B.3
-
33
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. 2011. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470:279–283. doi: 10.1038/nature09692.
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
34
-
-
84875931887
-
Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk
-
Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG, Kullo IJ, McCarty CA, Chisholm RL, Kho AN, Carlson CS, Larson EB, et al. 2013. Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Circulation 127:1377–1385. doi: 10.1161/CIRCULATIONAHA.112.000604.
-
(2013)
Circulation
, vol.127
, pp. 1377-1385
-
-
Ritchie, M.D.1
Denny, J.C.2
Zuvich, R.L.3
Crawford, D.C.4
Schildcrout, J.S.5
Bastarache, L.6
Ramirez, A.H.7
Mosley, J.D.8
Pulley, J.M.9
Basford, M.A.10
Bradford, Y.11
Rasmussen, L.V.12
Pathak, J.13
Chute, C.G.14
Kullo, I.J.15
McCarty, C.A.16
Chisholm, R.L.17
Kho, A.N.18
Carlson, C.S.19
Larson, E.B.20
more..
-
35
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, et al. 2015. Integrative analysis of 111 reference human epigenomes. Nature 518:317–330. doi: 10.1038/nature14248.
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
Ernst, J.3
Bilenky, M.4
Yen, A.5
Heravi-Moussavi, A.6
Kheradpour, P.7
Zhang, Z.8
Wang, J.9
Ziller, M.J.10
Amin, V.11
Whitaker, J.W.12
Schultz, M.D.13
Ward, L.D.14
Sarkar, A.15
Quon, G.16
Sandstrom, R.S.17
Eaton, M.L.18
Wu, Y.C.19
Pfenning, A.R.20
more..
-
36
-
-
84897855294
-
Obesity-associated variants within FTO form long-range functional connections with IRX3
-
Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, et al. 2014. Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature 507:371–375. doi: 10.1038/nature13138.
-
(2014)
Nature
, vol.507
, pp. 371-375
-
-
Smemo, S.1
Tena, J.J.2
Kim, K.H.3
Gamazon, E.R.4
Sakabe, N.J.5
Gómez-Marín, C.6
Aneas, I.7
Credidio, F.L.8
Sobreira, D.R.9
Wasserman, N.F.10
Lee, J.H.11
Puviindran, V.12
Tam, D.13
Shen, M.14
Son, J.E.15
Vakili, N.A.16
Sung, H.K.17
Naranjo, S.18
Acemel, R.D.19
Manzanares, M.20
more..
-
37
-
-
84355163093
-
DNA-binding factors shape the mouse methylome at distal regulatory regions
-
Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, Schöler A, van Nimwegen E, Wirbelauer C, Oakeley EJ, Gaidatzis D, Tiwari VK, Schübeler D. 2011. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 480:490–495. doi: 10.1038/nature10716.
-
(2011)
Nature
, vol.480
, pp. 490-495
-
-
Stadler, M.B.1
Murr, R.2
Burger, L.3
Ivanek, R.4
Lienert, F.5
Schöler, A.6
Van Nimwegen, E.7
Wirbelauer, C.8
Oakeley, E.J.9
Gaidatzis, D.10
Tiwari, V.K.11
Schübeler, D.12
-
38
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, Canfield TK, Diegel M, Dunn D, Ebersol AK, Frum T, et al. 2012. The accessible chromatin landscape of the human genome. Nature 489:75–82. doi: 10.1038/nature11232.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
Garg, K.11
John, S.12
Sandstrom, R.13
Bates, D.14
Boatman, L.15
Canfield, T.K.16
Diegel, M.17
Dunn, D.18
Ebersol, A.K.19
Frum, T.20
more..
-
39
-
-
84873086126
-
Chromatin marks identify critical cell types for fine mapping complex trait variants
-
Trynka G, Sandor C, Han B, Xu H, Stranger BE, Liu XS, Raychaudhuri S. 2013. Chromatin marks identify critical cell types for fine mapping complex trait variants. Nature Genetics 45:124–130. doi: 10.1038/ng.2504
-
(2013)
Nature Genetics
, vol.45
, pp. 124-130
-
-
Trynka, G.1
Sandor, C.2
Han, B.3
Xu, H.4
Stranger, B.E.5
Liu, X.S.6
Raychaudhuri, S.7
-
40
-
-
84867003195
-
Robust 4C-seq data analysis to screen for regulatory DNA interactions
-
van de Werken HJ, Landan G, Holwerda SJ, Hoichman M, Klous P, Chachik R, Splinter E, Valdes-Quezada C, Oz Y, Bouwman BA, Verstegen MJ, de Wit E, Tanay A, de Laat W. 2012. Robust 4C-seq data analysis to screen for regulatory DNA interactions. Nature Methods 9:969–972. doi: 10.1038/nmeth.2173
-
(2012)
Nature Methods
, vol.9
, pp. 969-972
-
-
Van De Werken, H.J.1
Landan, G.2
Holwerda, S.J.3
Hoichman, M.4
Klous, P.5
Chachik, R.6
Splinter, E.7
Valdes-Quezada, C.8
Oz, Y.9
Bouwman, B.A.10
Verstegen, M.J.11
De Wit, E.12
Tanay, A.13
De Laat, W.14
-
41
-
-
84897568607
-
A common genetic variant within SCN10A modulates cardiac SCN5A expression
-
van den Boogaard M, Smemo S, Burnicka-Turek O, Arnolds DE, van de Werken HJ, Klous P, McKean D, Muehlschlegel JD, Moosmann J, Toka O, Yang XH, Koopmann TT, Adriaens ME, Bezzina CR, de Laat W, Seidman C, Seidman JG, Christoffels VM, Nobrega MA, Barnett P, et al. 2014. A common genetic variant within SCN10A modulates cardiac SCN5A expression. The Journal of Clinical Investigation 124:1844–1852. doi: 10.1172/JCI73140
-
(2014)
The Journal of Clinical Investigation
, vol.124
, pp. 1844-1852
-
-
Van Den Boogaard, M.1
Smemo, S.2
Burnicka-Turek, O.3
Arnolds, D.E.4
Van De Werken, H.J.5
Klous, P.6
McKean, D.7
Muehlschlegel, J.D.8
Moosmann, J.9
Toka, O.10
Yang, X.H.11
Koopmann, T.T.12
Adriaens, M.E.13
Bezzina, C.R.14
De Laat, W.15
Seidman, C.16
Seidman, J.G.17
Christoffels, V.M.18
Nobrega, M.A.19
Barnett, P.20
more..
-
42
-
-
84863541919
-
Genetic variation in t-box binding element functionally affects SCN5A/SCN10A enhancer
-
van den Boogaard M, Wong LY, Tessadori F, Bakker ML, Dreizehnter LK, Wakker V, Bezzina CR, ’t Hoen PA, Bakkers J, Barnett P, Christoffels VM. 2012. Genetic variation in t-box binding element functionally affects SCN5A/SCN10A enhancer. The Journal of Clinical Investigation 122:2519–2530. doi: 10.1172/JCI62613.
-
(2012)
The Journal of Clinical Investigation
, vol.122
, pp. 2519-2530
-
-
Van Den Boogaard, M.1
Wong, L.Y.2
Tessadori, F.3
Bakker, M.L.4
Dreizehnter, L.K.5
Wakker, V.6
Bezzina, C.R.7
’T Hoen, P.A.8
Bakkers, J.9
Barnett, P.10
Christoffels, V.M.11
-
43
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, et al. 2013. Discovery and refinement of loci associated with lipid levels. Nature Genetics 45:1274–1283. doi: 10.1038/ng.2797.
-
(2013)
Nature Genetics
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
Peloso, G.M.4
Gustafsson, S.5
Kanoni, S.6
Ganna, A.7
Chen, J.8
Buchkovich, M.L.9
Mora, S.10
Beckmann, J.S.11
Bragg-Gresham, J.L.12
Chang, H.Y.13
Demirkan, A.14
Den Hertog, H.M.15
Do, R.16
Donnelly, L.A.17
Ehret, G.B.18
Esko, T.19
Feitosa, M.F.20
more..
-
44
-
-
79957588287
-
Genome partitioning of genetic variation for complex traits using common SNPs
-
Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, Cunningham JM, de Andrade M, Feenstra B, Feingold E, Hayes MG, Hill WG, Landi MT, Alonso A, Lettre G, Lin P, Ling H, Lowe W, Mathias RA, Melbye M, Pugh E, et al. 2011. Genome partitioning of genetic variation for complex traits using common SNPs. Nature Genetics 43:519–525. doi: 10.1038/ng.823
-
(2011)
Nature Genetics
, vol.43
, pp. 519-525
-
-
Yang, J.1
Manolio, T.A.2
Pasquale, L.R.3
Boerwinkle, E.4
Caporaso, N.5
Cunningham, J.M.6
De Andrade, M.7
Feenstra, B.8
Feingold, E.9
Hayes, M.G.10
Hill, W.G.11
Landi, M.T.12
Alonso, A.13
Lettre, G.14
Lin, P.15
Ling, H.16
Lowe, W.17
Mathias, R.A.18
Melbye, M.19
Pugh, E.20
more..
|