Blood Product Administration in the Critical Care and Perioperative Settings

Critical Care Clinics

Volumn 34, Issue 2, 2018, Pages 299-311

  Rygård, Sofie Louise ^a   Holst, Lars Broksø ^a   Perner, Anders ^a,b  

^a Rigshospitalet   (Denmark)

^b Centre for Research in Intensive Care   (Denmark)

Author keywords

Anemia; Critical care; ICU; Perioperative; Plasma; Platelets; Red blood cells; Thrombocytes

Indexed keywords

ERYTHROPOIETIN; HEPARIN; IRON; PLACEBO; TRANEXAMIC ACID; WARFARIN;

ANEMIA; ARTERIAL THROMBOEMBOLISM; BLEEDING DISORDER; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; DRUG EFFICACY; GASTROINTESTINAL HEMORRHAGE; HUMAN; INTENSIVE CARE; META ANALYSIS (TOPIC); PERIOPERATIVE PERIOD; PEROPERATIVE CARE; PLASMA TRANSFUSION; POSTOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK BENEFIT ANALYSIS; SURGICAL RISK; THROMBOCYTE TRANSFUSION; THROMBOEMBOLISM; TREATMENT OUTCOME; ERYTHROCYTE TRANSFUSION; PRACTICE GUIDELINE; STANDARDS;

ANEMIA; CRITICAL CARE; ERYTHROCYTE TRANSFUSION; HUMANS; PERIOPERATIVE CARE; PRACTICE GUIDELINES AS TOPIC;

EID: 85040698598     PISSN: 07490704     EISSN: 15578232     Source Type: Journal    
DOI: 10.1016/j.ccc.2017.12.005     Document Type: Review

References (76)

1. Bolton-Maggs PHB, Poles D, et al, editors, on behalf of the Serious Hazards of Transfusion (SHOT) Steering Group. The 2015 Annual SHOT report (2016). 2016. Available at: http://www.shotuk.org. Accessed September 1, 2017.
2. Wolfe, L.C., The membrane and the lesions of storage in preserved red cells. Transfusion 25:3 (1985), 185–203.
3. Berezina, T.L., Zaets, S.B., Morgan, C., et al. Influence of storage on red blood cell rheological properties. J Surg Res 102 (2002), 6–12.
4. Amrein, K., Valentin, A., Lanzer, G., et al. Blood reviews adverse events and safety issues in blood donation — a comprehensive review. Blood Rev 26 (2012), 33–42.
5. Department of health and human services. The 2011 National Blood Collection and Utilization Survey Report. 2011. Available at: https://www.aabb.org/research/hemovigilance/bloods. Accessed September 1, 2017.
6. Chang, R., Holcomb, J.B., Optimal fluid therapy for traumatic hemorrhagic shock. Crit Care Clin 33:1 (2017), 15–36.
7. Vincent, J.L., Baron, J.-F., Reinhart, K., et al. Anemia and blood transfusion in critically ill patients. JAMA 288:12 (2002), 1499–1507.
8. Corwin, H.L., Gettinger, A., Pearl, R.G., et al. The CRIT study: anemia and blood transfusion in the critically ill - current clinical practice in the United States. Crit Care Med 32 (2004), 39–52.
9. Perner, A., Haase, N., Guttormsen, A.B., et al. Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis. N Engl J Med 367:2 (2012), 82–83.
10. Pieracci, F.M., Stovall, R.T., Jaouen, B., et al. A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness. Crit Care Med 42:6 (2014), 1–10.
11. Litton, E., Baker, S., Erber, W.N., et al. Intravenous iron or placebo for anaemia in intensive care: the IRONMAN multicentre randomized blinded trial. Intensive Care Med 42:11 (2016), 1715–1722.
12. Corwin, H.L., Gettinger, A., Pearl, R.G., et al. Efficacy of recombinant human erythropoietin in critically ill patients. JAMA 288:22 (2002), 2827–2835.
13. Silver, M., Corwin, M.J., Bazan, A., et al. Efficacy of recombinant human erythropoietin in critically ill patients admitted to a long-term acute care facility: a randomized, double-blind, placebo-controlled trial. Crit Care Med 34:9 (2006), 2310–2316.
14. Corwin, H.L., Gettinger, A., Fabian, T., et al. Efficacy and safety of epoetin alfa in critically ill patients. N Engl J Med 357:10 (2007), 965–976.
15. Zarychanski, R., Turgeon, A.F., McIntyre, L.A., et al. Erythropoietin-receptor agonists in critically ill patients: a meta-analysis of randomized controlled trials. Can Med Assoc J 177:7 (2007), 725–734.
16. Zhao, C., Lin, Z., Luo, Q., et al. Efficacy and safety of erythropoietin to prevent acute kidney injury in patients with critical illness or perioperative care: a systematic review and meta-analysis of randomized controlled trials. J Cardiovasc Pharmacol 65:6 (2015), 593–600.
17. Shah, A., Roy, N.B., McKechnie, S., et al. Iron supplementation to treat anaemia in adult critical care patients: a systematic review and meta-analysis. Crit Care, 20(1), 2016, 306.
18. Stanworth, S.J., Walsh, T.S., Prescott, R.J., et al. Thrombocytopenia and platelet transfusion in UK critical care: a multicenter observational study. Transfusion 53 (2013), 1050–1058.
19. Hunt, B.J., Bleeding and coagulopathies in critical care. N Engl J Med 370 (2014), 847–859.
20. Stanworth, S.J., Walsh, T.S., Prescott, R.J., et al. A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time. Crit Care, 15(2), 2011, R108.
21. Reiter, N., Wesche, N., Perner, A., The majority of patients in septic shock are transfused with fresh-frozen plasma. Dan Med J 60:4 (2013), 4–7.
22. Dara, S., Rana, R., Afessa, B., et al. Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy. Crit Care Med 33:11 (2005), 2667–2671.
23. Tinmouth, A., Thompson, T., Arnold, D.M., et al. Utilization of frozen plasma in Ontario: a provincewide audit reveals a high rate of inappropriate transfusions. Transfusion 53 (2013), 2222–2229.
24. Karam, O., Tucci, M., Combescure, C., et al. Plasma transfusion strategies for critically ill patients (review). Cochrane Database Syst Rev(12), 2013 CD010654.
25. Shander, A., Knight, K., Thurer, R., et al. Prevalence and outcomes of anemia in surgery: a systematic review of the literature. Am J Med 116:7A (2004), 58s–69s.
26. Fowler, A.J., Ahmad, T., Phull, M.K., et al. Meta-analysis of the association between preoperative anaemia and mortality after surgery. Br J Surg 102:11 (2015), 1314–1324.
27. Musallam, K.M., Tamim, H.M., Richards, T., et al. Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet 378:9800 (2017), 1396–1407.
28. Kotze, A., Carter, L., Scally, A., Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle. Br J Anaesth 108:6 (2012), 943–952.
29. Goodnough, L.T., Shander, A., Spence, R., Bloodless medicine: clinical care without allogeneic blood transfusion. Transfusion 43:5 (2003), 668–676.
30. Goodnough, L.T., Shander, A., Patient blood management. Anesthesiology 116:6 (2012), 1367–1376.
31. Norgaard, A., De Lichtenberg, T.H., Nielsen, J., et al. Monitoring compliance with transfusion guidelines in hospital departments by electronic data capture. Blood Transfus 12:4 (2014), 509–519.
32. Baron, D.M., Metnitz, P.G.H., Fellinger, T., et al. Evaluation of clinical practice in perioperative patient blood management. Br J Anaesth 117:5 (2016), 610–616.
33. Meier, J., Filipescu, D., Pitarch, J.L., et al. Intraoperative transfusion practices in Europe. Br J Anaesth 116:2 (2016), 255–261.
34. Fischer, D.P., Zacharowski, K.D., Meybohm, P., Savoring every drop – vampire or mosquito?. Crit Care 18:306 (2014), 1–6.
35. Prakash, D., Anemia in the ICU: anemia of chronic disease versus anemia of acute illness. Crit Care Clin 28:3 (2012), 333–343.
36. Heming, N., Montravers, P., Lasocki, S., Iron deficiency in critically ill patients: highlighting the role of hepcidin. Crit Care, 15(2), 2011, 210.
37. Hébert, P.C., Wells, G., Blajchman, M., et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340:6 (1999), 409–417.
38. Walsh, T.S., Boyd, J.A., Watson, D., et al., RELIEVE Investigators. Restrictive versus liberal transfusion strategies for older mechanically ventilated critically ill patients: a randomized pilot trial. Crit Care Med 41:10 (2013), 2354–2363.
39. Holst, L.B., Haase, N., Wetterslev, J., et al. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med 371:15 (2014), 1381–1391.
40. Holst, L.B., Petersen, M.W., Haase, N., et al. Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis. BMJ, 350, 2015, h1354.
41. Docherty, A.B., Walsh, T.S., Anemia and blood transfusion in the critically ill patient with cardiovascular disease. Crit Care, 21(1), 2017, 61.
42. Carson, J.L., Brooks, M., Abbott, J., et al. Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease. Am Heart J 165:6 (2013), 964–971.
43. Murphy, G.J., Pike, K., Rogers, C.A., et al. Liberal or restrictive transfusion after cardiac surgery. N Engl J Med 372:11 (2015), 997–1008.
44. Docherty, A.B., O'Donnell, R., Brunskill, S., et al. Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis. BMJ, 352, 2016, i1351.
45. Zygun, D.A., Nortje, J., Hutchinson, P.J., et al. The effect of red blood cell transfusion on cerebral oxygenation and metabolism after severe traumatic brain injury. Crit Care Med 37:3 (2009), 1074–1078.
46. Robertson, C., Hannay, J., Yamal, J., et al. Effect of erythropoietin administration and after traumatic brain injury: a randomized clinical trial. JAMA 312:1 (2014), 36–47.
47. Hoeks, M.P.A., Kranenburg, F.J., Middelburg, R.A., et al. Impact of red blood cell transfusion strategies in haemato-oncological patients: a systematic review and meta-analysis. Br J Haematol 178:1 (2017), 137–151.
48. Prescott, L.S., Taylor, J.S., Lopez-Olivo, M.A., et al. How low should we go: a systematic review and meta-analysis of the impact of restrictive red blood cell transfusion strategies in oncology. Cancer Treat Rev 46 (2016), 1–8.
49. Roubinian, N., Carson, J.L., Red blood cell transfusion strategies in adult and pediatric patients with malignancy. Hematol Oncol Clin North Am 30:3 (2016), 529–540.
50. Lacroix, J., Hebert, P.C., Fergusson, D.A., et al. Age of transfused blood in critically ill adults. N Engl J Med 372:15 (2015), 1410–1418.
51. Cooper, D.J., McQuilten, Z.K., Nichol, A., et al. Age of red cells for transfusion and outcomes in critically ill adults. N Engl J Med 377:19 (2017), 1858–1867.
52. Yang, L., Stanworth, S., Hopewell, S., et al. Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials. Transfusion 52:8 (2012), 1673–1686.
53. Hall, D., Estcourt, L., Doree, C., et al. Plasma transfusions prior to insertion of central lines for people with abnormal coagulation (Review). Cochrane Database Syst Rev(9), 2016 CD011756.
54. Durila, M., Lukáš P., Astraverkhava, M., et al. Tracheostomy in intensive care unit patients can be performed without bleeding complications in case of normal thromboelastometry results (EXTEM CT) despite increased PT-INR: a prospective pilot study. BMC Anesthesiol, 15(1), 2015, 89.
55. Kaufman, R.M., Djulbegovic, B., Gernsheimer, T., et al. Platelet transfusion: a clinical practice guideline from the AABB. Ann Intern Med 162 (2015), 205–213.
56. National Blood Authority. Patient blood management guidelines: module 4-critical care. 2012;1–16. Available at: www.nba.gov.au. Accessed September 1, 2017.
57. Kozek-Langenecker, S.A., Ahmed, A.B., Afshari, A., et al. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology First update 2016. Eur J Anaesthesiol 34 (2017), 332–395.
58. Pasricha, S.-R.S., Flecknoe-Brown, S.C., Allen, K.J., et al. Diagnosis and management of iron deficiency anaemia: a clinical update. Med J Aust 193:9 (2010), 525–532.
59. National Blood Authority. Patient blood management guidelines: module 2 perioperative. 2012. Available at: www.nba.gov.au. Accessed September 1, 2017.
60. Froessler, B., Palm, P., Weber, I., et al. The important role for intravenous iron in perioperative patient blood management in major abdominal surgery. Ann Surg 264:1 (2016), 41–46.
61. Henry, D.A., Carless, P.A., Moxey, A.J., et al. Pre-operative autologous donation for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev(4), 2001 CD003602.
62. Bouchard, D., Marcheix, B., Al-Shamary, S., et al. Preoperative autologous blood donation reduces the need for allogeneic blood products: a prospective randomized study. Can J Surg 51:6 (2008), 422–427.
63. Jakovina Blazekovic, S., Bicanic, G., Hrabac, P., et al. Pre-operative autologous blood donation versus no blood donation in total knee arthroplasty: a prospective randomised trial. Int Orthop 38:2 (2014), 341–346.
64. Daniels, P.R., Peri-procedural management of patients taking oral anticoagulants. BMJ, 351, 2015, h2391.
65. Douketis, J.D., Spyropoulos, A.C., Kaatz, S., et al. Perioperative bridging anticoagulation in patients with atrial fibrillation. N Engl J Med 373:9 (2015), 823–833.
66. Fominskiy, E., Putzu, A., Monaco, F., et al. Liberal transfusion strategy improves survival in perioperative but not in critically ill patients. A meta-analysis of randomised trials. Br J Anaesth 115:4 (2015), 511–519.
67. Villanueva, C., Colomo, A., Bosch, A., et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 368 (2013), 11–21.
68. Roberts, I., Shakur, H., Coats, T., et al. The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess 17:10 (2013), 1–80.
69. Myles, P.S., Smith, J.A., Forbes, A., et al. Tranexamic acid in patients undergoing coronary-artery surgery. N Engl J Med 376:2 (2017), 136–148.
70. Henry, D.A., Carless, P.A., Moxey, A.J., et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion (Review) Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev(1), 2011 CD001886.
71. Dewan, Y., Komolafe, E.O., Mejía-Mantilla, J.H., et al. CRASH-3-tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial. Trials, 13(1), 2012, 87.
72. Roberts, I., Coats, T., Edwards, P., et al. HALT-IT - tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial. Trials, 15(1), 2014, 450.
73. Carless, P.A., Henry, D.A., Moxey, A.J., et al. Cell salvage for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev(3), 2010 CD001888.
74. Wikkelsø A., Wetterslev, J., Møller, A., et al. Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding. Cochrane Database Syst Rev(8), 2016 CD007871.
75. Carson, J.L., Terrin, M.L., Noveck, H., et al. Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med 365:26 (2011), 2453–2462.
76. Carson, J.L., Sieber, F., Cook, D.R., et al. Liberal versus restrictive blood transfusion strategy: 3-year survival and cause of death results from the FOCUS randomised controlled trial. Lancet 385 (2015), 1183–1189.