A national study of plasma use in critical care: Clinical indications, dose and effect on prothrombin time

Critical Care

Volumn 15, Issue 2, 2011, Pages

  Stanworth, Simon J ^a   Walsh, Timothy S ^b   Prescott, Robin J ^c   Lee, Robert J ^c   Watson, Douglas M ^d   Wyncoll, Duncan ^e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d SCOTTISH NATIONAL BLOOD TRANSFUSION SERVICE   (United Kingdom)

^e ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA;

ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYOPRECIPITATE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OBSERVATIONAL STUDY; PLASMA TRANSFUSION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTHROMBIN TIME; TREATMENT OUTCOME; ADULT; BLOOD COMPONENT THERAPY; CLINICAL PRACTICE; CLINICAL TRIAL; METHODOLOGY; PLASMA; STATISTICS; UNITED KINGDOM; UTILIZATION REVIEW;

ADULT; BLOOD COMPONENT TRANSFUSION; GREAT BRITAIN; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; PHYSICIAN'S PRACTICE PATTERNS; PLASMA; PROSPECTIVE STUDIES; PROTHROMBIN TIME; TREATMENT OUTCOME;

EID: 79953291679     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc10129     Document Type: Article

References (37)

1. Lauzier F, Cook D, Griffith L, Upton J, Crowther M. Fresh frozen plasma transfusion in critically ill patients. Crit Care Med 2007, 35:1655-1659. 10.1097/01.CCM.0000269370.59214.97, 17522577.
2. Stanworth SJ, Grant-Casey J, Lowe D, Laffan M, New H, Murphy MF, Allard S. The use of fresh frozen plasma in England: high levels of inappropriate use in adults and children. Transfusion 2011, 51:62-70. 10.1111/j.1537-2995.2010.02798.x, 20804532.
3. Rao MP, Boralessa H, Morgan C, Soni N, Goldhill DR, Brett SJ, Boralessa H, Contreras M, . North Thames Blood Interest Group Blood component use in critically ill patients. Anaesthesia 2002, 57:530-534. 10.1046/j.1365-2044.2002.02514.x, 12010265, North Thames Blood Interest Group.
4. Palo R, Capraro L, Hovilehto S, Koivuranta M, Krusius T, Loponen E, Mäntykoski R, Pentti J, Pitkänen O, Raitakari M, Rimpiläinen J, Salmenperä M, Salo H, Mäki T. Population-based audit of fresh frozen plasma transfusion practices. Transfusion 2006, 46:1921-1925. 10.1111/j.1537-2995.2006.00998.x, 17076847.
5. Chakraverty R, Davidson S, Peggs K, Stross P, Garrard C, Littlewood TJ. The incidence and cause of coagulopathies in an intensive care population. Br J Haematol 1996, 93:460-463. 10.1046/j.1365-2141.1996.5101050.x, 8639449.
6. Report and Summary 2009: Serious Hazards of Transfusion. , http://www.shotuk.org/shot-reports/report-and-summary-2009/
7. Stainsby D, Jones H, Asher D, Atterbury C, Boncinelli A, Brant L, Chapman CE, Davison K, Gerrard R, Gray A, Knowles S, Love EM, Milkins C, McClelland DB, Norfolk DR, Soldan K, Taylor C, Revill J, Williamson LM, Cohen H, . SHOT Steering Group Serious hazards of transfusion: a decade of hemovigilance in the UK. Transfus Med Rev 2006, 20:273-282. 10.1016/j.tmrv.2006.05.002, 17008165, SHOT Steering Group.
8. Holness L, Knippen MA, Simmons L, Lachenbruch PA. Fatalities caused by TRALI. Transfus Med Rev 2004, 18:184-188. 10.1016/j.tmrv.2004.03.004, 15248168.
9. Dara SI, Rana R, Afessa B, Moore SB, Gajic O. Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy. Crit Care Med 2005, 33:2667-2671. 10.1097/01.CCM.0000186745.53059.F0, 16276195.
10. Gajic O, Dzik WH, Toy P. Fresh frozen plasma and platelet transfusion for nonbleeding patients in the intensive care unit: benefit or harm?. Crit Care Med 2006, 34(5 Suppl):S170-S173. 10.1097/01.CCM.0000214288.88308.26, 16617262.
11. Rana R, Fernández-Pérez E, Khan SA, Rana S, Winters JL, Lesnick TG, Moore SB, Gajic O. Transfusion-related acute lung injury and pulmonary edema in critically ill patients: a retrospective study. Transfusion 2006, 46:1478-1483. 10.1111/j.1537-2995.2006.00930.x, 16965572.
12. Khan H, Belsher J, Yilmaz M, Afessa B, Winters JL, Moore SB, Hubmayr RD, Gajic O. Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest 2007, 131:1308-1314. 10.1378/chest.06-3048, 17400669.
13. Popovsky MA. Transfusion-associated circulatory overload: the plot thickens. Transfusion 2009, 49:2-4. 10.1111/j.1537-2995.2008.02010.x, 19140808.
14. Marik PE, Sibbald WJ. Effect of stored-blood transfusion on oxygen delivery in patients with sepsis. JAMA 1993, 269:3024-3029. 10.1001/jama.269.23.3024, 8501845.
15. Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E. A multicenter, randomised, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 1999, 340:409-417. 10.1056/NEJM199902113400601, 9971864.
16. Tinmouth A, Fergusson D, Yee IC, Hébert PC, . ABLE Investigators; Canadian Critical Care Trials Group Clinical consequences of red cell storage in the critically ill. Transfusion 2006, 46:2014-2027. 10.1111/j.1537-2995.2006.01026.x, 17076859, ABLE Investigators; Canadian Critical Care Trials Group.
17. Koch CG, Liang L, Sessler DI, Figueroa P, Hoeltge GA, Mihaljevic T, Blackstone EH. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med 2008, 358:1229-1239. 10.1056/NEJMoa070403, 18354101.
18. Walsh TS, Stanworth SJ, Prescott RJ, Lee RJ, Watson DM, Wyncoll D, . Writing Committee of the Intensive Care Study of Coagulopathy Investigators Prevalence, management, and outcomes of critically ill patients with prothrombin time prolongation in United Kingdom intensive care units. Crit Care Med 2010, 38:1939-1946. Writing Committee of the Intensive Care Study of Coagulopathy Investigators.
19. Walsh TS, McClelland DB, Lee RJ, Garrioch M, Maciver CR, McArdle F, Crofts SL, Mellor I, . ATICS Study Group Prevalence of ischaemic heart disease at admission to intensive care and its influence on red cell transfusion thresholds: multicentre Scottish Study. Br J Anaesth 2005, 94:445-452. 10.1093/bja/aei073, 15708870, ATICS Study Group.
20. O'Shaughnessy DF, Atterbury C, Bolton Maggs P, Murphy M, Thomas D, Yates S, Williamson LM, . British Committee for Standards in Haematology, Blood Transfusion Task Force Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol 2004, 126:11-28. British Committee for Standards in Haematology, Blood Transfusion Task Force.
21. Practice parameter for the use of fresh-frozen plasma, cryoprecipitate, and platelets. Fresh-Frozen Plasma, Cryoprecipitate, and Platelets Administration Practice Guidelines Development Task Force of the College of American Pathologists. JAMA 1994, 271:777-781. 10.1001/jama.271.10.777, 8114215.
22. Chowdhury P, Saayman AG, Paulus U, Findlay GP, Collins PW. Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patients. Br J Haematol 2004, 125:69-73. 10.1111/j.1365-2141.2004.04868.x, 15015971.
23. Abdel-Wahab OI, Healy B, Dzik WH. Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities. Transfusion 2006, 46:1279-1285. 10.1111/j.1537-2995.2006.00891.x, 16934060.
24. Holland LL, Brooks JP. Toward rational fresh frozen plasma transfusion. Am J Clin Pathol 2006, 126:133-139. 10.1309/NQXHUG7HND78LFFK, 16753596.
25. Dzik WH. Predicting hemorrhage using preoperative coagulation screening assays. Curr Hematol Rep 2004, 3:324-330.
26. Stansbury LG, Dutton RP, Stein DM, Bochicchio GV, Scalea TM, Hess JR. Controversy in trauma resuscitation: do ratios of plasma to red blood cells matter?. Transfus Med Rev 2009, 23:255-265. 10.1016/j.tmrv.2009.06.002, 19765515.
27. Johansson PI, Stensballe J, Rosenberg I, Hilsløv TL, Jørgensen L, Secher NH. Proactive administration of platelets and plasma for patients with a ruptured abdominal aortic aneurysm: evaluating a change in transfusion practice. Transfusion 2007, 47:593-598. 10.1111/j.1537-2995.2007.01160.x, 17381616.
28. Segal JB, Dzik WH, . Transfusion Medicine/Hemostasis Clinical Trials Network Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review. Transfusion 2005, 45:1413-1425. 10.1111/j.1537-2995.2005.00546.x, 16131373, Transfusion Medicine/Hemostasis Clinical Trials Network.
29. Stanworth SJ, Brunskill S, Hyde CJ, McClelland DBL, Murphy MF. Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials. Br J Haematol 2004, 126:139-152. 10.1111/j.1365-2141.2004.04973.x, 15198745.
30. Deitcher SR. Interpretation of the international normalised ratio in patients with liver disease. Lancet 2002, 359:47-48. 10.1016/S0140-6736(02)07282-3, 11809190.
31. Holland L, Sarode R. Should plasma be transfused prophylactically before invasive procedures?. Curr Opin Hematol 2006, 13:447-451. 10.1097/01.moh.0000245688.47333.b6, 17053457.
32. Li G, Kojicic M, Reriani MK, Fernández Pérez ER, Thakur L, Kashyap R, Van Buskirk CM, Gajic O. Long-term survival and quality of life after transfusion associated pulmonary edema in critically ill medical patients. Chest 2009, 137:783-789. 10.1378/chest.09-0841, 2851555, 19837827.
33. Vamvakas EC, Blajchman MA. Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood 2009, 113:3406-3417. 10.1182/blood-2008-10-167643, 19188662.
34. Watson GA, Sperry JL, Rosengart MR, Minei JP, Harbrecht BG, Moore EE, Cuschieri J, Maier RV, Billiar TR, Peitzman AB, . Inflammation and Host Response to Injury Investigators Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma 2009, 67:221-227. 10.1097/TA.0b013e3181ad5957, 19667872, Inflammation and Host Response to Injury Investigators.
35. Silliman CC, Ambruso DR, Boshkov LK. Transfusion-related acute lung injury. Blood 2005, 105:2266-2273. 10.1182/blood-2004-07-2929, 15572582.
36. Stanworth SJ. The evidence-based use of FFP and cryoprecipitate for abnormalities of coagulation tests and clinical coagulopathy. Hematology Am Soc Hematol Educ Program 2007:179-186.
37. Keeling D. International Normalized Ratio in patients not on vitamin K antagonists. J Thromb Haemost 2007, 5:188-189. 10.1111/j.1538-7836.2006.02286.x, 17067366.