Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Wang, Wenbiao ^a,b   Li, Geng ^c   De, Wu ^d   Luo, Zhen ^b   Pan, Pan ^a   Tian, Mingfu ^a   Wang, Yingchong ^a   Xiao, Feng ^a   Li, Aixin ^a   Wu, Kailang ^a   Liu, Xiaohong ^c   Rao, Lang ^a   Liu, Fang ^a   Liu, Yingle ^a,b   Wu, Jianguo ^a,b  

^a WUHAN UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

^c GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^d GUANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NONSTRUCTURAL PROTEIN 5; CASP1 PROTEIN, MOUSE; NLRP3 PROTEIN, MOUSE; NS5 PROTEIN, FLAVIVIRUS; VIRAL PROTEIN;

ACTIVATION ENERGY; CELL; CHEMICAL BINDING; IMMUNE RESPONSE; INDUCED RESPONSE; INFECTIOUS DISEASE; PROTEIN; RODENT; VIRUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; BRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EMBRYO; FEMALE; GENE KNOCKDOWN; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; KIDNEY; LIVER; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SPLEEN; ZIKA FEVER; ZIKA VIRUS; AEDES; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; CHLOROCEBUS AETHIOPS; ENZYME ACTIVATION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NCTC CLONE 929 CELL LINE; NEUTROPHIL; PATHOLOGY; THP-1 CELL LINE; VERO CELL LINE; VIROLOGY;

MUS; ZIKA VIRUS;

AEDES; ANIMALS; BRAIN; CASPASE 1; CELL LINE; CERCOPITHECUS AETHIOPS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; KIDNEY; L CELLS (CELL LINE); LIVER; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SPLEEN; THP-1 CELLS; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85040609922     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02645-3     Document Type: Article

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