A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

Science

Volumn 358, Issue 6365, 2017, Pages 933-936

  Yuan, Ling ^a,b   Huang, Xing Yao ^c   Liu, Zhong Yu ^c   Zhang, Feng ^a,b   Zhu, Xing Liang ^a,b   Yu, Jiu Yang ^c   Ji, Xue ^c   Xu, Yan Peng ^c   Li, Guanghui ^a,b   Li, Cui ^a,b   Wang, Hong Jiang ^c   Deng, Yong Qiang ^c   Wu, Menghua ^d   Cheng, Meng Li ^c,e   Ye, Qing ^c   Xie, Dong Yang ^c,e   Li, Xiao Feng ^c   Wang, Xiangxi ^f   Shi, Weifeng ^g   Hu, Baoyang ^d   Shi, Pei Yong ^h   Xu, Zhiheng ^a,b,i   Qin, Cheng Feng ^c   more..

^a Shenzhen Fundamental Research Institutions   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d INSTITUTE OF ZOOLOGY   (China)

^e ANHUI MEDICAL UNIVERSITY   (China)

^f INSTITUTE OF BIOPHYSICS   (China)

^g SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^h University of Texas Medical Branch School of Medicine   (United States)

ⁱ BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; PROTEIN PRM; SERINE; UNCLASSIFIED DRUG; VIRAL PROTEIN; PRM PROTEIN, FLAVIVIRUS; VIRUS ENVELOPE PROTEIN;

CELLS AND CELL COMPONENTS; DISEASE INCIDENCE; EPIDEMIC; EVOLUTIONARY BIOLOGY; INFECTIVITY; MORTALITY; MUTATION; PHYLOGENETICS; PROTEIN; VIRUS;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GENE MUTATION; INCIDENCE; MICROCEPHALY; MOLECULAR EVOLUTION; MORTALITY RATE; MOUSE; NEURAL STEM CELL; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; VIRUS STRAIN; VIRUS VIRULENCE; ZIKA VIRUS; ANIMAL; COMPLICATION; EPIDEMIC; GENETICS; HAMSTER; HUMAN; MUTATION; PATHOGENICITY; POLYNESIA; TUMOR CELL LINE; VIROLOGY; WESTERN HEMISPHERE; ZIKA FEVER;

ASIA; CENTRAL AMERICA; FRENCH POLYNESIA; NORTH AMERICA; SOUTH AMERICA;

MUS; ZIKA VIRUS;

AMERICAS; AMINO ACID SUBSTITUTION; ANIMALS; ASPARAGINE; CELL LINE, TUMOR; CRICETINAE; DISEASE OUTBREAKS; HUMANS; INCIDENCE; MICE; MICROCEPHALY; MUTATION; NEURAL STEM CELLS; POLYNESIA; SERINE; VIRAL ENVELOPE PROTEINS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85030531753     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aam7120     Document Type: Article

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