-
1
-
-
37549056216
-
The roles of therapy-induced autophagy and necrosis in cancer treatment
-
Amaravadi, R. K., and Thompson, C. B. (2007). The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin. Cancer Res. 13, 7271-7279. doi: 10.1158/1078-0432.CCR-07-1595
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 7271-7279
-
-
Amaravadi, R.K.1
Thompson, C.B.2
-
2
-
-
84959471006
-
Regulators of iron homeostasis: new players in metabolism, cell death, and disease
-
Bogdan, A. R., Miyazawa, M., Hashimoto, K., and Tsuji, Y. (2016). Regulators of iron homeostasis: new players in metabolism, cell death, and disease. Trends Biochem. Sci. 41, 274-286. doi: 10.1016/j.tibs.2015.11.012
-
(2016)
Trends Biochem. Sci
, vol.41
, pp. 274-286
-
-
Bogdan, A.R.1
Miyazawa, M.2
Hashimoto, K.3
Tsuji, Y.4
-
3
-
-
81055127888
-
System xc(-) cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS
-
Bridges, R. J., Natale, N. R., and Patel, S. A. (2012). System xc(-) cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS. Br. J. Pharmacol. 165, 20-34. doi: 10.1111/j.1476-5381.2011.01480.x
-
(2012)
Br. J. Pharmacol
, vol.165
, pp. 20-34
-
-
Bridges, R.J.1
Natale, N.R.2
Patel, S.A.3
-
4
-
-
33646192717
-
Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake
-
Chen, H., Zheng, C., Zhang, Y., Chang, Y. Z., Qian, Z. M., and Shen, X. (2006). Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake. Int. J. Biochem. Cell Biol. 38, 1402-1416. doi: 10.1016/j.biocel.2006.02.006
-
(2006)
Int. J. Biochem. Cell Biol
, vol.38
, pp. 1402-1416
-
-
Chen, H.1
Zheng, C.2
Zhang, Y.3
Chang, Y.Z.4
Qian, Z.M.5
Shen, X.6
-
5
-
-
84921647344
-
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-gamma-lyase function
-
Chen, L., Li, X., Liu, L., Yu, B., Xue, Y., and Liu, Y. (2015). Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-gamma-lyase function. Oncol. Rep. 33, 1465-1474. doi: 10.3892/or.2015.3712
-
(2015)
Oncol. Rep
, vol.33
, pp. 1465-1474
-
-
Chen, L.1
Li, X.2
Liu, L.3
Yu, B.4
Xue, Y.5
Liu, Y.6
-
6
-
-
84954484374
-
Regulated necrosis: disease relevance and therapeutic opportunities
-
Conrad, M., Angeli, J. P., Vandenabeele, P., and Stockwell, B. R. (2016). Regulated necrosis: disease relevance and therapeutic opportunities. Nat. Rev. Drug Discov. 15, 348-366. doi: 10.1038/nrd.2015.6
-
(2016)
Nat. Rev. Drug Discov
, vol.15
, pp. 348-366
-
-
Conrad, M.1
Angeli, J.P.2
Vandenabeele, P.3
Stockwell, B.R.4
-
7
-
-
84861541814
-
Ferroptosis: an iron-dependent form of nonapoptotic cell death
-
Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., et al. (2012). Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149, 1060-1072. doi: 10.1016/j.cell.2012.03.042
-
(2012)
Cell
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
-
8
-
-
84901323900
-
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
-
Dixon, S. J., Patel, D. N., Welsch, M., Skouta, R., Lee, E. D., Hayano, M., et al. (2014). Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. eLife 3:e02523. doi: 10.7554/eLife.02523
-
(2014)
ELife
, vol.3
-
-
Dixon, S.J.1
Patel, D.N.2
Welsch, M.3
Skouta, R.4
Lee, E.D.5
Hayano, M.6
-
9
-
-
84937119776
-
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
-
Dixon, S. J., Winter, G. E., Musavi, L. S., Lee, E. D., Snijder, B., Rebsamen, M., et al. (2015). Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death. ACS Chem. Biol. 10, 1604-1609. doi: 10.1021/acschembio.5b00245
-
(2015)
ACS Chem. Biol
, vol.10
, pp. 1604-1609
-
-
Dixon, S.J.1
Winter, G.E.2
Musavi, L.S.3
Lee, E.D.4
Snijder, B.5
Rebsamen, M.6
-
10
-
-
0037932865
-
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
-
Dolma, S., Lessnick, S. L., Hahn, W. C., and Stockwell, B. R. (2003). Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell 3, 285-296. doi: 10.1016/S1535-6108(03)00050-3
-
(2003)
Cancer Cell
, vol.3
, pp. 285-296
-
-
Dolma, S.1
Lessnick, S.L.2
Hahn, W.C.3
Stockwell, B.R.4
-
11
-
-
84957431913
-
Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
-
Eling, N., Reuter, L., Hazin, J., Hamacher-Brady, A., and Brady, N. R. (2015). Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells. Oncoscience 2, 517-532. doi: 10.18632/oncoscience.160
-
(2015)
Oncoscience
, vol.2
, pp. 517-532
-
-
Eling, N.1
Reuter, L.2
Hazin, J.3
Hamacher-Brady, A.4
Brady, N.R.5
-
12
-
-
84897442012
-
Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities
-
Fatokun, A. A., Dawson, V. L., and Dawson, T. M. (2014). Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities. Br. J. Pharmacol. 171, 2000-2016
-
(2014)
Br. J. Pharmacol
, vol.171
, pp. 2000-2016
-
-
Fatokun, A.A.1
Dawson, V.L.2
Dawson, T.M.3
-
13
-
-
84925286831
-
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
-
Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., et al. (2014). Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat. Cell Biol. 16, 1180-1191. doi: 10.1038/ncb3064
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 1180-1191
-
-
Friedmann Angeli, J.P.1
Schneider, M.2
Proneth, B.3
Tyurina, Y.Y.4
Tyurin, V.A.5
Hammond, V.J.6
-
14
-
-
84896134891
-
New biological perspectives for the improvement of the efficacy of sorafenib in hepatocellular carcinoma
-
Galmiche, A., Chauffert, B., and Barbare, J. C. (2014). New biological perspectives for the improvement of the efficacy of sorafenib in hepatocellular carcinoma. Cancer Lett. 346, 159-162. doi: 10.1016/j.canlet.2013.12.028
-
(2014)
Cancer Lett
, vol.346
, pp. 159-162
-
-
Galmiche, A.1
Chauffert, B.2
Barbare, J.C.3
-
15
-
-
84982123825
-
Ferroptosis is an autophagic cell death process
-
Gao, M., Monian, P., Pan, Q., Zhang, W., Xiang, J., and Jiang, X. (2016). Ferroptosis is an autophagic cell death process. Cell Res. 26, 1021-1032. doi: 10.1038/cr.2016.95
-
(2016)
Cell Res
, vol.26
, pp. 1021-1032
-
-
Gao, M.1
Monian, P.2
Pan, Q.3
Zhang, W.4
Xiang, J.5
Jiang, X.6
-
16
-
-
84937525519
-
Glutaminolysis and transferrin regulate ferroptosis
-
Gao, M., Monian, P., Quadri, N., Ramasamy, R., and Jiang, X. (2015). Glutaminolysis and transferrin regulate ferroptosis. Mol. Cell 59, 298-308. doi: 10.1016/j.molcel.2015.06.011
-
(2015)
Mol. Cell
, vol.59
, pp. 298-308
-
-
Gao, M.1
Monian, P.2
Quadri, N.3
Ramasamy, R.4
Jiang, X.5
-
17
-
-
84959194657
-
Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate
-
Greenshields, A. L., Shepherd, T. G., and Hoskin, D. W. (2016). Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate. Mol. Carcinog. 56, 75-93. doi: 10.1002/mc.22474
-
(2016)
Mol. Carcinog
, vol.56
, pp. 75-93
-
-
Greenshields, A.L.1
Shepherd, T.G.2
Hoskin, D.W.3
-
18
-
-
84962909319
-
Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells
-
Hasegawa, M., Takahashi, H., Rajabi, H., Alam, M., Suzuki, Y., Yin, L., et al. (2016). Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells. Oncotarget 7, 11756-11769. doi: 10.18632/oncotarget.7598
-
(2016)
Oncotarget
, vol.7
, pp. 11756-11769
-
-
Hasegawa, M.1
Takahashi, H.2
Rajabi, H.3
Alam, M.4
Suzuki, Y.5
Yin, L.6
-
19
-
-
84954379174
-
Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
-
Hayano, M., Yang, W. S., Corn, C. K., Pagano, N. C., and Stockwell, B. R. (2016). Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation. Cell Death Differ. 23, 270-278. doi: 10.1038/cdd.2015.93
-
(2016)
Cell Death Differ
, vol.23
, pp. 270-278
-
-
Hayano, M.1
Yang, W.S.2
Corn, C.K.3
Pagano, N.C.4
Stockwell, B.R.5
-
20
-
-
84976292806
-
Autophagy promotes ferroptosis by degradation of ferritin
-
Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., et al. (2016). Autophagy promotes ferroptosis by degradation of ferritin. Autophagy 12, 1425-1428. doi: 10.1080/15548627.2016.1187366
-
(2016)
Autophagy
, vol.12
, pp. 1425-1428
-
-
Hou, W.1
Xie, Y.2
Song, X.3
Sun, X.4
Lotze, M.T.5
Zeh, H.J.6
-
21
-
-
84968854657
-
Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib
-
Houessinon, A., Francois, C., Sauzay, C., Louandre, C., Mongelard, G., Godin, C., et al. (2016). Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib. Mol. Cancer 15:38. doi: 10.1186/s12943-016-0526-2
-
(2016)
Mol. Cancer
, vol.15
, pp. 38
-
-
Houessinon, A.1
Francois, C.2
Sauzay, C.3
Louandre, C.4
Mongelard, G.5
Godin, C.6
-
22
-
-
23844486685
-
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
-
Huang, Y., Dai, Z., Barbacioru, C., and Sadee, W. (2005). Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res. 65, 7446-7454. doi: 10.1158/0008-5472.CAN-04-4267
-
(2005)
Cancer Res
, vol.65
, pp. 7446-7454
-
-
Huang, Y.1
Dai, Z.2
Barbacioru, C.3
Sadee, W.4
-
23
-
-
84926387317
-
Ferroptosis as a p53-mediated activity during tumour suppression
-
Jiang, L., Kon, N., Li, T., Wang, S. J., Su, T., Hibshoosh, H., et al. (2015). Ferroptosis as a p53-mediated activity during tumour suppression. Nature 520, 57-62. doi: 10.1038/nature14344
-
(2015)
Nature
, vol.520
, pp. 57-62
-
-
Jiang, L.1
Kon, N.2
Li, T.3
Wang, S.J.4
Su, T.5
Hibshoosh, H.6
-
24
-
-
0028329172
-
Apoptosis Its significance in cancer and cancer therapy
-
Kerr, J. F., Winterford, C. M., and Harmon, B. V. (1994). Apoptosis. Its significance in cancer and cancer therapy. Cancer 73, 2013-2026. doi: 10.1002/1097-0142(19940415)73:8<2013::AID-CNCR2820730802>3.0.CO;2-J
-
(1994)
Cancer
, vol.73
, pp. 2013-2026
-
-
Kerr, J.F.1
Winterford, C.M.2
Harmon, B.V.3
-
25
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo, Y., Kanzawa, T., Sawaya, R., and Kondo, S. (2005). The role of autophagy in cancer development and response to therapy. Nat. Rev. Cancer 5, 726-734. doi: 10.1038/nrc1692
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
26
-
-
0021341216
-
Microcytic hypochromic anemia associated with renal cell carcinoma
-
Kroll, M. H., Jiji, V., and Jiji, R. (1984). Microcytic hypochromic anemia associated with renal cell carcinoma. South Med. J. 77, 635-637. doi: 10.1097/00007611-198405000-00024
-
(1984)
South Med. J
, vol.77
, pp. 635-637
-
-
Kroll, M.H.1
Jiji, V.2
Jiji, R.3
-
27
-
-
84943390843
-
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
-
Kwon, M. Y., Park, E., Lee, S. J., and Chung, S. W. (2015). Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death. Oncotarget 6, 24393-24403. doi: 10.18632/oncotarget.5162
-
(2015)
Oncotarget
, vol.6
, pp. 24393-24403
-
-
Kwon, M.Y.1
Park, E.2
Lee, S.J.3
Chung, S.W.4
-
28
-
-
33645941521
-
Unraveling the role of autophagy in cancer
-
Levine, B. (2006). Unraveling the role of autophagy in cancer. Autophagy 2, 65-66. doi: 10.4161/auto.2.2.2457
-
(2006)
Autophagy
, vol.2
, pp. 65-66
-
-
Levine, B.1
-
29
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
Li, T., Kon, N., Jiang, L., Tan, M., Ludwig, T., Zhao, Y., et al. (2012). Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 149, 1269-1283. doi: 10.1016/j.cell.2012.04.026
-
(2012)
Cell
, vol.149
, pp. 1269-1283
-
-
Li, T.1
Kon, N.2
Jiang, L.3
Tan, M.4
Ludwig, T.5
Zhao, Y.6
-
30
-
-
84962835198
-
Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging
-
Li, T., Liu, X., Jiang, L., Manfredi, J., Zha, S., and Gu, W. (2016). Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging. Oncotarget 7, 11838-11849. doi: 10.18632/oncotarget.7864
-
(2016)
Oncotarget
, vol.7
, pp. 11838-11849
-
-
Li, T.1
Liu, X.2
Jiang, L.3
Manfredi, J.4
Zha, S.5
Gu, W.6
-
31
-
-
84981203604
-
Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells
-
Lin, R., Zhang, Z., Chen, L., Zhou, Y., Zou, P., Feng, C., et al. (2016). Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells. Cancer Lett. 381, 165-175. doi: 10.1016/j.canlet.2016.07.033
-
(2016)
Cancer Lett
, vol.381
, pp. 165-175
-
-
Lin, R.1
Zhang, Z.2
Chen, L.3
Zhou, Y.4
Zou, P.5
Feng, C.6
-
32
-
-
78651286142
-
HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells
-
Liu, L., Yang, M., Kang, R., Wang, Z., Zhao, Y., Yu, Y., et al. (2011). HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia 25, 23-31. doi: 10.1038/leu.2010.225
-
(2011)
Leukemia
, vol.25
, pp. 23-31
-
-
Liu, L.1
Yang, M.2
Kang, R.3
Wang, Z.4
Zhao, Y.5
Yu, Y.6
-
33
-
-
79955578079
-
MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11
-
Liu, X. X., Li, X. J., Zhang, B., Liang, Y. J., Zhou, C. X., Cao, D. X., et al. (2011). MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. FEBS Lett. 585, 1363-1367. doi: 10.1016/j.febslet.2011.04.018
-
(2011)
FEBS Lett
, vol.585
, pp. 1363-1367
-
-
Liu, X.X.1
Li, X.J.2
Zhang, B.3
Liang, Y.J.4
Zhou, C.X.5
Cao, D.X.6
-
34
-
-
84940944514
-
The 5-lipoxygenase inhibitor zileuton confers neuroprotection against glutamate oxidative damage by inhibiting ferroptosis
-
Liu, Y., Wang, W., Li, Y., Xiao, Y., Cheng, J., and Jia, J. (2015). The 5-lipoxygenase inhibitor zileuton confers neuroprotection against glutamate oxidative damage by inhibiting ferroptosis. Biol. Pharm. Bull. 38, 1234-1239. doi: 10.1248/bpb.b15-00048
-
(2015)
Biol. Pharm. Bull
, vol.38
, pp. 1234-1239
-
-
Liu, Y.1
Wang, W.2
Li, Y.3
Xiao, Y.4
Cheng, J.5
Jia, J.6
-
35
-
-
84919432703
-
The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells
-
Louandre, C., Marcq, I., Bouhlal, H., Lachaier, E., Godin, C., Saidak, Z., et al. (2015). The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells. Cancer Lett. 356, 971-977. doi: 10.1016/j.canlet.2014.11.014
-
(2015)
Cancer Lett
, vol.356
, pp. 971-977
-
-
Louandre, C.1
Marcq, I.2
Bouhlal, H.3
Lachaier, E.4
Godin, C.5
Saidak, Z.6
-
36
-
-
85017015542
-
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
-
Ma, S., Henson, E. S., Chen, Y., and Gibson, S. B. (2016). Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell Death Dis. 7:e2307. doi: 10.1038/cddis.2016.208
-
(2016)
Cell Death Dis
, vol.7
-
-
Ma, S.1
Henson, E.S.2
Chen, Y.3
Gibson, S.B.4
-
37
-
-
84941550824
-
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
-
Ooko, E., Saeed, M. E., Kadioglu, O., Sarvi, S., Colak, M., Elmasaoudi, K., et al. (2015). Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Phytomedicine 22, 1045-1054. doi: 10.1016/j.phymed.2015.08.002
-
(2015)
Phytomedicine
, vol.22
, pp. 1045-1054
-
-
Ooko, E.1
Saeed, M.E.2
Kadioglu, O.3
Sarvi, S.4
Colak, M.5
Elmasaoudi, K.6
-
38
-
-
2442464889
-
Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks
-
Pommier, Y., Sordet, O., Antony, S., Hayward, R. L., and Kohn, K. W. (2004). Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene 23, 2934-2949. doi: 10.1038/sj.onc.1207515
-
(2004)
Oncogene
, vol.23
, pp. 2934-2949
-
-
Pommier, Y.1
Sordet, O.2
Antony, S.3
Hayward, R.L.4
Kohn, K.W.5
-
39
-
-
84979872952
-
Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer
-
Roh, J. L., Kim, E. H., Jang, H. J., Park, J. Y., and Shin, D. (2016). Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer. Cancer Lett. 381, 96-103. doi: 10.1016/j.canlet.2016.07.035
-
(2016)
Cancer Lett
, vol.381
, pp. 96-103
-
-
Roh, J.L.1
Kim, E.H.2
Jang, H.J.3
Park, J.Y.4
Shin, D.5
-
40
-
-
77956309955
-
The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages
-
Rossi, A., Pergola, C., Koeberle, A., Hoffmann, M., Dehm, F., Bramanti, P., et al. (2010). The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages. Br. J. Pharmacol. 161, 555-570. doi: 10.1111/j.1476-5381.2010.00930.x
-
(2010)
Br. J. Pharmacol
, vol.161
, pp. 555-570
-
-
Rossi, A.1
Pergola, C.2
Koeberle, A.3
Hoffmann, M.4
Dehm, F.5
Bramanti, P.6
-
41
-
-
27844530663
-
Redox imbalance in cystine/glutamate transporter-deficient mice
-
Sato, H., Shiiya, A., Kimata, M., Maebara, K., Tamba, M., Sakakura, Y., et al. (2005). Redox imbalance in cystine/glutamate transporter-deficient mice. J. Biol. Chem. 280, 37423-37429. doi: 10.1074/jbc.M506439200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 37423-37429
-
-
Sato, H.1
Shiiya, A.2
Kimata, M.3
Maebara, K.4
Tamba, M.5
Sakakura, Y.6
-
42
-
-
84996807781
-
Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
-
Sehm, T., Rauh, M., Wiendieck, K., Buchfelder, M., Eyupoglu, I. Y., and Savaskan, N. E. (2016). Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis. Oncotarget 7, 74630-74647. doi: 10.18632/oncotarget.11858
-
(2016)
Oncotarget
, vol.7
, pp. 74630-74647
-
-
Sehm, T.1
Rauh, M.2
Wiendieck, K.3
Buchfelder, M.4
Eyupoglu, I.Y.5
Savaskan, N.E.6
-
43
-
-
84965000436
-
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
-
Shimada, K., Skouta, R., Kaplan, A., Yang, W. S., Hayano, M., Dixon, S. J., et al. (2016). Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat. Chem. Biol. 12, 497-503. doi: 10.1038/nchembio.2079
-
(2016)
Nat. Chem. Biol
, vol.12
, pp. 497-503
-
-
Shimada, K.1
Skouta, R.2
Kaplan, A.3
Yang, W.S.4
Hayano, M.5
Dixon, S.J.6
-
44
-
-
84897059782
-
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models
-
Skouta, R., Dixon, S. J., Wang, J., Dunn, D. E., Orman, M., Shimada, K., et al. (2014). Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J. Am. Chem. Soc. 136, 4551-4556. doi: 10.1021/ja411006a
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 4551-4556
-
-
Skouta, R.1
Dixon, S.J.2
Wang, J.3
Dunn, D.E.4
Orman, M.5
Shimada, K.6
-
45
-
-
84887437596
-
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
-
Sui, X., Chen, R., Wang, Z., Huang, Z., Kong, N., Zhang, M., et al. (2013). Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis. 4:e838. doi: 10.1038/cddis.2013.350
-
(2013)
Cell Death Dis
, vol.4
-
-
Sui, X.1
Chen, R.2
Wang, Z.3
Huang, Z.4
Kong, N.5
Zhang, M.6
-
46
-
-
84952639010
-
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
-
Sun, X., Ou, Z., Chen, R., Niu, X., Chen, D., Kang, R., et al. (2016). Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells. Hepatology 63, 173-184. doi: 10.1002/hep.28251
-
(2016)
Hepatology
, vol.63
, pp. 173-184
-
-
Sun, X.1
Ou, Z.2
Chen, R.3
Niu, X.4
Chen, D.5
Kang, R.6
-
47
-
-
84947035915
-
HSPB1 as a novel regulator of ferroptotic cancer cell death
-
Sun, X., Ou, Z., Xie, M., Kang, R., Fan, Y., Niu, X., et al. (2015). HSPB1 as a novel regulator of ferroptotic cancer cell death. Oncogene 34, 5617-5625. doi: 10.1038/onc.2015.32
-
(2015)
Oncogene
, vol.34
, pp. 5617-5625
-
-
Sun, X.1
Ou, Z.2
Xie, M.3
Kang, R.4
Fan, Y.5
Niu, X.6
-
48
-
-
84862779149
-
Development of small-molecule probes that selectively kill cells induced to express mutant RAS
-
Weiwer, M., Bittker, J. A., Lewis, T. A., Shimada, K., Yang, W. S., Macpherson, L., et al. (2012). Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorg. Med. Chem. Lett. 22, 1822-1826. doi: 10.1016/j.bmcl.2011.09.047
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 1822-1826
-
-
Weiwer, M.1
Bittker, J.A.2
Lewis, T.A.3
Shimada, K.4
Yang, W.S.5
Macpherson, L.6
-
49
-
-
84957429081
-
Ferroptosis: process and function
-
Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., et al. (2016). Ferroptosis: process and function. Cell Death Differ. 23, 369-379. doi: 10.1038/cdd.2015.158
-
(2016)
Cell Death Differ
, vol.23
, pp. 369-379
-
-
Xie, Y.1
Hou, W.2
Song, X.3
Yu, Y.4
Huang, J.5
Sun, X.6
-
50
-
-
34250372956
-
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
-
Yagoda, N., Von Rechenberg, M., Zaganjor, E., Bauer, A. J., Yang, W. S., Fridman, D. J., et al. (2007). RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 447, 864-868. doi: 10.1038/nature05859
-
(2007)
Nature
, vol.447
, pp. 864-868
-
-
Yagoda, N.1
Von Rechenberg, M.2
Zaganjor, E.3
Bauer, A.J.4
Yang, W.S.5
Fridman, D.J.6
-
51
-
-
84874038196
-
Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells
-
Yamaguchi, H., Hsu, J. L., Chen, C. T., Wang, Y. N., Hsu, M. C., Chang, S. S., et al. (2013). Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. Clin. Cancer Res. 19, 845-854. doi: 10.1158/1078-0432.CCR-12-2621
-
(2013)
Clin. Cancer Res
, vol.19
, pp. 845-854
-
-
Yamaguchi, H.1
Hsu, J.L.2
Chen, C.T.3
Wang, Y.N.4
Hsu, M.C.5
Chang, S.S.6
-
52
-
-
84983666736
-
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
-
Yang, W. S., Kim, K. J., Gaschler, M. M., Patel, M., Shchepinov, M. S., and Stockwell, B. R. (2016). Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc. Natl. Acad. Sci. U.S.A. 113, E4966-E4975. doi: 10.1073/pnas.1603244113
-
(2016)
Proc. Natl. Acad. Sci. U.S.A
, vol.113
, pp. E4966-E4975
-
-
Yang, W.S.1
Kim, K.J.2
Gaschler, M.M.3
Patel, M.4
Shchepinov, M.S.5
Stockwell, B.R.6
-
53
-
-
84862939534
-
Identification of simple compounds with microtubule-binding activity that inhibit cancer cell growth with high potency
-
Yang, W. S., Shimada, K., Delva, D., Patel, M., Ode, E., Skouta, R., et al. (2012). Identification of simple compounds with microtubule-binding activity that inhibit cancer cell growth with high potency. ACS Med. Chem. Lett. 3, 35-38. doi: 10.1021/ml200195s
-
(2012)
ACS Med. Chem. Lett
, vol.3
, pp. 35-38
-
-
Yang, W.S.1
Shimada, K.2
Delva, D.3
Patel, M.4
Ode, E.5
Skouta, R.6
-
54
-
-
84892685001
-
Regulation of ferroptotic cancer cell death by GPX4
-
Yang, W. S., Sriramaratnam, R., Welsch, M. E., Shimada, K., Skouta, R., Viswanathan, V. S., et al. (2014). Regulation of ferroptotic cancer cell death by GPX4. Cell 156, 317-331. doi: 10.1016/j.cell.2013.12.010
-
(2014)
Cell
, vol.156
, pp. 317-331
-
-
Yang, W.S.1
Sriramaratnam, R.2
Welsch, M.E.3
Shimada, K.4
Skouta, R.5
Viswanathan, V.S.6
-
55
-
-
40849085503
-
Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
-
Yang, W. S., and Stockwell, B. R. (2008). Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chem. Biol. 15, 234-245. doi: 10.1016/j.chembiol.2008.02.010
-
(2008)
Chem. Biol
, vol.15
, pp. 234-245
-
-
Yang, W.S.1
Stockwell, B.R.2
-
56
-
-
0037441379
-
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
-
Yant, L. J., Ran, Q., Rao, L., Van Remmen, H., Shibatani, T., Belter, J. G., et al. (2003). The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults. Free Radic. Biol. Med. 34, 496-502. doi: 10.1016/S0891-5849(02)01360-6
-
(2003)
Free Radic. Biol. Med
, vol.34
, pp. 496-502
-
-
Yant, L.J.1
Ran, Q.2
Rao, L.3
Van Remmen, H.4
Shibatani, T.5
Belter, J.G.6
-
57
-
-
85024121807
-
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
-
Yu, Y., Xie, Y., Cao, L., Yang, L., Yang, M., Lotze, M. T., et al. (2015). The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents. Mol. Cell. Oncol. 2:e1054549. doi: 10.1080/23723556.2015.1054549
-
(2015)
Mol. Cell. Oncol
, vol.2
-
-
Yu, Y.1
Xie, Y.2
Cao, L.3
Yang, L.4
Yang, M.5
Lotze, M.T.6
|