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Volumn 15, Issue 2, 2015, Pages 117-129

Role of innate and adaptive immune mechanisms in cardiac injury and repair

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; CARDIOVASCULAR MORTALITY; HEART INJURY; HEART MUSCLE FIBROSIS; HOMEOSTASIS; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MYOCARDITIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; FIBROSIS; HEART DISEASE; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; WOUND HEALING;

EID: 84923061601     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3800     Document Type: Review
Times cited : (462)

References (154)
  • 1
    • 84922991360 scopus 로고    scopus 로고
    • An exceptionally preserved arthropod cardiovascular system from the early Cambrian
    • Ma, X., Cong, P., Hou, X., Edgecombe, G. D. &Strausfeld, N. J. An exceptionally preserved arthropod cardiovascular system from the early Cambrian. Nature Commun. 5, 3560 (2014).
    • (2014) Nature Commun. , vol.5 , pp. 3560
    • Ma, X.1    Cong, P.2    Hou, X.3    Edgecombe, G.D.4    Strausfeld, N.J.5
  • 2
    • 7644239149 scopus 로고    scopus 로고
    • Drosophila, an emerging model for cardiac disease
    • Bier, E. & Bodmer, R. Drosophila, an emerging model for cardiac disease. Gene 342, 1-11 (2004).
    • (2004) Gene , vol.342 , pp. 1-11
    • Bier, E.1    Bodmer, R.2
  • 3
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Lozano, R. et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2095-2128 (2012).
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1
  • 4
    • 84860997131 scopus 로고    scopus 로고
    • An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile
    • Pinto, A. R. et al. An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLoS ONE. 7, e36814 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e36814
    • Pinto, A.R.1
  • 5
    • 84892450644 scopus 로고    scopus 로고
    • Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation
    • Epelman, S. et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 40, 91-104 (2014).
    • (2014) Immunity , vol.40 , pp. 91-104
    • Epelman, S.1
  • 6
    • 36549033197 scopus 로고    scopus 로고
    • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
    • Nahrendorf, M. et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 204, 3037-3047 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 3037-3047
    • Nahrendorf, M.1
  • 7
    • 84872166189 scopus 로고    scopus 로고
    • Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
    • Swirski, F. K. & Nahrendorf, M. Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science 339, 161-166 (2013).
    • (2013) Science , vol.339 , pp. 161-166
    • Swirski, F.K.1    Nahrendorf, M.2
  • 8
    • 63449086433 scopus 로고    scopus 로고
    • Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
    • Choi, J. H. et al. Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves. J. Exp. Med. 206, 497-505 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 497-505
    • Choi, J.H.1
  • 9
    • 0032544201 scopus 로고    scopus 로고
    • Resident cardiac mast cells degranulate and release preformed TNF-α, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion
    • Frangogiannis, N. G. et al. Resident cardiac mast cells degranulate and release preformed TNF-α, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. Circulation 98, 699-710 (1998).
    • (1998) Circulation , vol.98 , pp. 699-710
    • Frangogiannis, N.G.1
  • 10
    • 84887439701 scopus 로고    scopus 로고
    • B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction
    • Zouggari, Y. et al. B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction. Nature Med. 19, 1273-1280 (2013).
    • (2013) Nature Med. , vol.19 , pp. 1273-1280
    • Zouggari, Y.1
  • 11
    • 84908110191 scopus 로고    scopus 로고
    • Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function
    • Saxena, A. et al. Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function. Am. J. Physiol. Heart Circ. Physiol. 307, H1233-H1242 (2014).
    • (2014) Am. J. Physiol. Heart Circ. Physiol. , vol.307 , pp. H1233-H1242
    • Saxena, A.1
  • 12
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2012 update: A report from the American Heart Association
    • Roger, V. L. et al. Heart disease and stroke statistics - 2012 update: a report from the American Heart Association. Circulation 125, e2-e220 (2012).
    • (2012) Circulation , vol.125 , pp. e2-e220
    • Roger, V.L.1
  • 13
    • 84856703950 scopus 로고    scopus 로고
    • Genetics of inherited cardiomyopathy
    • Jacoby, D. & McKenna, W. J. Genetics of inherited cardiomyopathy. Eur. Heart J. 33, 296-304 (2012).
    • (2012) Eur. Heart J. , vol.33 , pp. 296-304
    • Jacoby, D.1    McKenna, W.J.2
  • 14
    • 84923049818 scopus 로고    scopus 로고
    • Cell death-associated molecular-pattern molecules: Inflammatory signaling and control
    • Sangiuliano, B., Perez, N. M., Moreira, D. F. & Belizario, J. E. Cell death-associated molecular-pattern molecules: inflammatory signaling and control. Mediators Inflamm. 2014, 821043 (2014).
    • (2014) Mediators Inflamm. , vol.2014 , pp. 821043
    • Sangiuliano, B.1    Perez, N.M.2    Moreira, D.F.3    Belizario, J.E.4
  • 15
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger, P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12, 991-1045 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 16
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, C. A. Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54 Pt. 1, 1-13 (1989).
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 18
    • 83755195135 scopus 로고    scopus 로고
    • The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse
    • Mezzaroma, E. et al. The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. Proc. Natl Acad. Sci. USA 108, 19725-19730 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 19725-19730
    • Mezzaroma, E.1
  • 19
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O. & Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 20
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • Rathinam, V. A. et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nature Immunol. 11, 395-402 (2010).
    • (2010) Nature Immunol. , vol.11 , pp. 395-402
    • Rathinam, V.A.1
  • 21
    • 0032701642 scopus 로고    scopus 로고
    • Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium
    • Frantz, S. et al. Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. J. Clin. Invest. 104, 271-280 (1999).
    • (1999) J. Clin. Invest. , vol.104 , pp. 271-280
    • Frantz, S.1
  • 22
    • 0842285548 scopus 로고    scopus 로고
    • Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices
    • Birks, E. J. et al. Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices. J. Heart Lung Transplant. 23, 228-235 (2004).
    • (2004) J. Heart Lung Transplant. , vol.23 , pp. 228-235
    • Birks, E.J.1
  • 23
    • 84857033063 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptor 4 and human monocyte subsets in acute myocardial infarction
    • Kashiwagi, M. et al. Differential expression of Toll-like receptor 4 and human monocyte subsets in acute myocardial infarction. Atherosclerosis 221, 249-253 (2012).
    • (2012) Atherosclerosis , vol.221 , pp. 249-253
    • Kashiwagi, M.1
  • 24
    • 74549178528 scopus 로고    scopus 로고
    • Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
    • Arslan, F. et al. Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody. Circulation 121, 80-90 (2010).
    • (2010) Circulation , vol.121 , pp. 80-90
    • Arslan, F.1
  • 25
    • 77952672109 scopus 로고    scopus 로고
    • Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemia
    • Fallach, R. et al. Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemia. J. Mol. Cell Cardiol. 48, 1236-1244 (2010).
    • (2010) J. Mol. Cell Cardiol. , vol.48 , pp. 1236-1244
    • Fallach, R.1
  • 26
    • 12344302942 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock
    • Binck, B. W. et al. Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock. Am. J. Physiol. Heart Circ. Physiol. 288, H577-H583 (2005).
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288 , pp. H577-H583
    • Binck, B.W.1
  • 27
    • 1242336786 scopus 로고    scopus 로고
    • Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
    • Oyama, J. et al. Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 109, 784-789 (2004).
    • (2004) Circulation , vol.109 , pp. 784-789
    • Oyama, J.1
  • 28
    • 4944254828 scopus 로고    scopus 로고
    • Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia
    • Tavener, S. A. et al. Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ. Res. 95, 700-707 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 700-707
    • Tavener, S.A.1
  • 29
    • 84860705893 scopus 로고    scopus 로고
    • Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
    • Oka, T. et al. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature 485, 251-255 (2012).
    • (2012) Nature , vol.485 , pp. 251-255
    • Oka, T.1
  • 30
  • 31
    • 79951679204 scopus 로고    scopus 로고
    • Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
    • Kawaguchi, M. et al. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 123, 594-604 (2011).
    • (2011) Circulation , vol.123 , pp. 594-604
    • Kawaguchi, M.1
  • 32
    • 79953318392 scopus 로고    scopus 로고
    • RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice
    • McCartney, S. A. et al. RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice. J. Clin. Invest. 121, 1497-1507 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1497-1507
    • McCartney, S.A.1
  • 33
    • 84877310689 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis
    • Philip, J., Xu, Z., Bowles, N. E. & Vallejo, J. G. Cardiac-specific overexpression of melanoma differentiation-associated gene-5 protects mice from lethal viral myocarditis. Circ. Heart Fail. 6, 326-334 (2013).
    • (2013) Circ. Heart Fail. , vol.6 , pp. 326-334
    • Philip, J.1    Xu, Z.2    Bowles, N.E.3    Vallejo, J.G.4
  • 34
    • 84871669136 scopus 로고    scopus 로고
    • Quantitative expression of C-type lectin receptors in humans and mice
    • Lech, M. et al. Quantitative expression of C-type lectin receptors in humans and mice. Int. J. Mol. Sci. 13, 10113-10131 (2012).
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 10113-10131
    • Lech, M.1
  • 36
    • 33847724471 scopus 로고    scopus 로고
    • The mechanistic basis of infarct healing
    • Frangogiannis, N. G. The mechanistic basis of infarct healing. Antioxid. Redox. Signal. 8, 1907-1939 (2006).
    • (2006) Antioxid. Redox. Signal. , vol.8 , pp. 1907-1939
    • Frangogiannis, N.G.1
  • 38
    • 0030022925 scopus 로고    scopus 로고
    • Comparative effect of C3a and C5a on adhesion molecule expression on neutrophils and endothelial cells
    • Foreman, K. E., Glovsky, M. M., Warner, R. L., Horvath, S. J. & Ward, P. A. Comparative effect of C3a and C5a on adhesion molecule expression on neutrophils and endothelial cells. Inflammation 20, 1-9 (1996).
    • (1996) Inflammation , vol.20 , pp. 1-9
    • Foreman, K.E.1    Glovsky, M.M.2    Warner, R.L.3    Horvath, S.J.4    Ward, P.A.5
  • 39
    • 33947732711 scopus 로고    scopus 로고
    • Mast cell deficient W/Wv mice have lower serum IL-6 and less cardiac tissue necrosis than their normal littermates following myocardial ischemia-reperfusion
    • Bhattacharya, K. et al. Mast cell deficient W/Wv mice have lower serum IL-6 and less cardiac tissue necrosis than their normal littermates following myocardial ischemia-reperfusion. Int. J. Immunopathol. Pharmacol. 20, 69-74 (2007).
    • (2007) Int. J. Immunopathol. Pharmacol. , vol.20 , pp. 69-74
    • Bhattacharya, K.1
  • 40
    • 33144455158 scopus 로고    scopus 로고
    • Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction
    • Ayach, B. B. et al. Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction. Proc. Natl Acad. Sci. USA 103, 2304-2309 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2304-2309
    • Ayach, B.B.1
  • 41
    • 0036753694 scopus 로고    scopus 로고
    • Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis
    • Waskow, C., Paul, S., Haller, C., Gassmann, M. & Rodewald, H. R. Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. Immunity 17, 277-288 (2002).
    • (2002) Immunity , vol.17 , pp. 277-288
    • Waskow, C.1    Paul, S.2    Haller, C.3    Gassmann, M.4    Rodewald, H.R.5
  • 42
    • 0026490182 scopus 로고
    • Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury
    • Dreyer, W. J. et al. Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury. Circ. Res. 71, 1518-1524 (1992).
    • (1992) Circ. Res. , vol.71 , pp. 1518-1524
    • Dreyer, W.J.1
  • 43
    • 84881588821 scopus 로고    scopus 로고
    • Evaluation and management of patients with isolated neutropenia
    • Newburger, P. E. & Dale, D. C. Evaluation and management of patients with isolated neutropenia. Semin. Hematol. 50, 198-206 (2013).
    • (2013) Semin. Hematol. , vol.50 , pp. 198-206
    • Newburger, P.E.1    Dale, D.C.2
  • 44
    • 0038170601 scopus 로고    scopus 로고
    • Resident cardiac mast cells and ischemia-reperfusion injury
    • Singh, M. & Saini, H. K. Resident cardiac mast cells and ischemia-reperfusion injury. J. Cardiovasc. Pharmacol. Ther. 8, 135-148 (2003).
    • (2003) J. Cardiovasc. Pharmacol. Ther. , vol.8 , pp. 135-148
    • Singh, M.1    Saini, H.K.2
  • 45
    • 77957943307 scopus 로고    scopus 로고
    • Intravascular danger signals guide neutrophils to sites of sterile inflammation
    • McDonald, B. et al. Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330, 362-366 (2010).
    • (2010) Science , vol.330 , pp. 362-366
    • McDonald, B.1
  • 46
    • 84863543219 scopus 로고    scopus 로고
    • Intravital 2-photon imaging of leukocyte trafficking in beating heart
    • Li, W. et al. Intravital 2-photon imaging of leukocyte trafficking in beating heart. J. Clin. Invest. 122, 2499-2508 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 2499-2508
    • Li, W.1
  • 47
    • 0033514260 scopus 로고    scopus 로고
    • Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions
    • Gwechenberger, M. et al. Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions. Circulation 99, 546-551 (1999).
    • (1999) Circulation , vol.99 , pp. 546-551
    • Gwechenberger, M.1
  • 48
    • 0026577328 scopus 로고
    • Neutrophil adherence to isolated adult cardiac myocytes. Induction by cardiac lymph collected during ischemia and reperfusion
    • Youker, K. et al. Neutrophil adherence to isolated adult cardiac myocytes. Induction by cardiac lymph collected during ischemia and reperfusion. J. Clin. Invest. 89, 602-609 (1992).
    • (1992) J. Clin. Invest. , vol.89 , pp. 602-609
    • Youker, K.1
  • 49
    • 0026445442 scopus 로고
    • Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence
    • Entman, M. L. et al. Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence. J. Clin. Invest. 90, 1335-1345 (1992).
    • (1992) J. Clin. Invest. , vol.90 , pp. 1335-1345
    • Entman, M.L.1
  • 50
    • 0025289588 scopus 로고
    • Neutrophil adherence to isolated adult canine myocytes. Evidence for a CD18-dependent mechanism
    • Entman, M. L. et al. Neutrophil adherence to isolated adult canine myocytes. Evidence for a CD18-dependent mechanism. J. Clin. Invest. 85, 1497-1506 (1990).
    • (1990) J. Clin. Invest. , vol.85 , pp. 1497-1506
    • Entman, M.L.1
  • 51
    • 0033766347 scopus 로고    scopus 로고
    • C5a-stimulated human neutrophils use a subset of β2 integrins to support the adhesion-dependent phase of superoxide production
    • Tyagi, S., Klickstein, L. B. & Nicholson-Weller, A. C5a-stimulated human neutrophils use a subset of β2 integrins to support the adhesion-dependent phase of superoxide production. J. Leukoc. Biol. 68, 679-686 (2000).
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 679-686
    • Tyagi, S.1    Klickstein, L.B.2    Nicholson-Weller, A.3
  • 52
    • 20844452374 scopus 로고    scopus 로고
    • Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction
    • Kawakami, R. et al. Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction. Circulation 110, 3306-3312 (2004).
    • (2004) Circulation , vol.110 , pp. 3306-3312
    • Kawakami, R.1
  • 53
    • 0020583038 scopus 로고
    • Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog
    • Romson, J. L. et al. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 67, 1016-1023 (1983).
    • (1983) Circulation , vol.67 , pp. 1016-1023
    • Romson, J.L.1
  • 54
    • 0022519328 scopus 로고
    • Reduction of myocardial infarct size by neutrophil depletion: Effect of duration of occlusion
    • Jolly, S. R. et al. Reduction of myocardial infarct size by neutrophil depletion: effect of duration of occlusion. Am. Heart J. 112, 682-690 (1986).
    • (1986) Am. Heart J. , vol.112 , pp. 682-690
    • Jolly, S.R.1
  • 55
    • 0014325451 scopus 로고
    • The origin and kinetics of mononuclear phagocytes
    • Van Furth, R. & Cohn, Z. A. The origin and kinetics of mononuclear phagocytes. J. Exp. Med. 128, 415-435 (1968).
    • (1968) J. Exp. Med. , vol.128 , pp. 415-435
    • Van Furth, R.1    Cohn, Z.A.2
  • 56
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux, F. et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845 (2010).
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1
  • 57
    • 84859508307 scopus 로고    scopus 로고
    • A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    • Schulz, C. et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336, 86-90 (2012).
    • (2012) Science , vol.336 , pp. 86-90
    • Schulz, C.1
  • 58
    • 84872765982 scopus 로고    scopus 로고
    • Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
    • Yona, S. et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 38, 79-91 (2013).
    • (2013) Immunity , vol.38 , pp. 79-91
    • Yona, S.1
  • 59
    • 84876775203 scopus 로고    scopus 로고
    • Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
    • Hashimoto, D. et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity. 38, 792-804 (2013).
    • (2013) Immunity , vol.38 , pp. 792-804
    • Hashimoto, D.1
  • 60
    • 84885454468 scopus 로고    scopus 로고
    • Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
    • Guilliams, M. et al. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J. Exp. Med. 210, 1977-1992 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 1977-1992
    • Guilliams, M.1
  • 61
    • 84884352076 scopus 로고    scopus 로고
    • Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes
    • Jakubzick, C. et al. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity. 39, 599-610 (2013).
    • (2013) Immunity , vol.39 , pp. 599-610
    • Jakubzick, C.1
  • 62
    • 80051959957 scopus 로고    scopus 로고
    • The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes
    • Hanna, R. N. et al. The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes. Nature Immunol. 12, 778-785 (2011).
    • (2011) Nature Immunol. , vol.12 , pp. 778-785
    • Hanna, R.N.1
  • 63
    • 84880838451 scopus 로고    scopus 로고
    • Origin of monocytes and macrophages in a committed progenitor
    • Hettinger, J. et al. Origin of monocytes and macrophages in a committed progenitor. Nature Immunol. 14, 821-830 (2013).
    • (2013) Nature Immunol. , vol.14 , pp. 821-830
    • Hettinger, J.1
  • 64
    • 77449102329 scopus 로고    scopus 로고
    • Comparison of gene expression profiles between human and mouse monocyte subsets
    • Ingersoll, M. A. et al. Comparison of gene expression profiles between human and mouse monocyte subsets. Blood 115, e10-e19 (2010).
    • (2010) Blood , vol.115 , pp. e10-e19
    • Ingersoll, M.A.1
  • 65
    • 34547728312 scopus 로고    scopus 로고
    • Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
    • Auffray, C. et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 317, 666-670 (2007).
    • (2007) Science , vol.317 , pp. 666-670
    • Auffray, C.1
  • 66
    • 84876207357 scopus 로고    scopus 로고
    • Nr4a1-dependent Ly6Clowmonocytes monitor endothelial cells and orchestrate their disposal
    • Carlin, L. M. et al. Nr4a1-dependent Ly6Clowmonocytes monitor endothelial cells and orchestrate their disposal. Cell 153, 362-375 (2013).
    • (2013) Cell , vol.153 , pp. 362-375
    • Carlin, L.M.1
  • 67
    • 33846867740 scopus 로고    scopus 로고
    • Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy
    • Frangogiannis, N. G. et al. Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation 115, 584-592 (2007).
    • (2007) Circulation , vol.115 , pp. 584-592
    • Frangogiannis, N.G.1
  • 68
    • 84901056045 scopus 로고    scopus 로고
    • high monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium
    • high monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ. Res.114, 1611-1622 (2014).
    • (2014) Circ. Res. , vol.114 , pp. 1611-1622
    • Hilgendorf, I.1
  • 69
    • 78650418632 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction
    • Leuschner, F. et al. Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction. Circ. Res. 107, 1364-1373 (2010).
    • (2010) Circ. Res. , vol.107 , pp. 1364-1373
    • Leuschner, F.1
  • 70
    • 68149119072 scopus 로고    scopus 로고
    • Identification of splenic reservoir monocytes and their deployment to inflammatory sites
    • Swirski, F. K. et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 325, 612-616 (2009).
    • (2009) Science , vol.325 , pp. 612-616
    • Swirski, F.K.1
  • 71
    • 84863115989 scopus 로고    scopus 로고
    • Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis
    • Leuschner, F. et al. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J. Exp. Med. 209, 123-137 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 123-137
    • Leuschner, F.1
  • 72
    • 84908227801 scopus 로고    scopus 로고
    • Progressive replacement of embryo-derived cardiac macrophages with age
    • Molawi, K. et al. Progressive replacement of embryo-derived cardiac macrophages with age. J. Exp. Med. 211, 2151-2158 (2014).
    • (2014) J. Exp. Med. , vol.211 , pp. 2151-2158
    • Molawi, K.1
  • 73
    • 84904214756 scopus 로고    scopus 로고
    • Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome
    • Bracey, N. A. et al. Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome. J. Biol. Chem. 289, 19571-19584 (2014).
    • (2014) J. Biol. Chem. , vol.289 , pp. 19571-19584
    • Bracey, N.A.1
  • 74
    • 84872696318 scopus 로고    scopus 로고
    • The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β
    • Bracey, N. A. et al. The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β. Exp. Physiol. 98, 462-472 (2013).
    • (2013) Exp. Physiol. , vol.98 , pp. 462-472
    • Bracey, N.A.1
  • 75
    • 48749107414 scopus 로고    scopus 로고
    • + inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
    • + inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii. Immunity 29, 306-317 (2008).
    • (2008) Immunity , vol.29 , pp. 306-317
    • Dunay, I.R.1
  • 76
    • 79956319462 scopus 로고    scopus 로고
    • The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes
    • Kim, Y. G. et al. The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity 34, 769-780 (2011).
    • (2011) Immunity , vol.34 , pp. 769-780
    • Kim, Y.G.1
  • 77
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • van Amerongen, M. J., Harmsen, M. C., van Rooijen, N., Petersen, A. H. & van Luyn, M. J. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am. J. Pathol. 170, 818-829 (2007).
    • (2007) Am. J. Pathol. , vol.170 , pp. 818-829
    • Van Amerongen, M.J.1    Harmsen, M.C.2    Van Rooijen, N.3    Petersen, A.H.4    Van Luyn, M.J.5
  • 78
    • 77950323431 scopus 로고    scopus 로고
    • Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis
    • Panizzi, P. et al. Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J. Am. Coll. Cardiol. 55, 1629-1638 (2010).
    • (2010) J. Am. Coll. Cardiol. , vol.55 , pp. 1629-1638
    • Panizzi, P.1
  • 79
    • 20944449211 scopus 로고    scopus 로고
    • CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts
    • Dewald, O. et al. CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ. Res. 96, 881-889 (2005).
    • (2005) Circ. Res. , vol.96 , pp. 881-889
    • Dewald, O.1
  • 80
    • 80155200721 scopus 로고    scopus 로고
    • Therapeutic siRNA silencing in inflammatory monocytes in mice
    • Leuschner, F. et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature Biotech. 29, 1005-1010 (2011).
    • (2011) Nature Biotech. , vol.29 , pp. 1005-1010
    • Leuschner, F.1
  • 81
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • Serbina, N. V. & Pamer, E. G. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nature Immunol. 7, 311-317 (2006).
    • (2006) Nature Immunol. , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 82
    • 33745027735 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction
    • Zhou, L. et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ. Res. 98, 1177-1185 (2006).
    • (2006) Circ. Res. , vol.98 , pp. 1177-1185
    • Zhou, L.1
  • 83
    • 84896799309 scopus 로고    scopus 로고
    • Macrophages are required for neonatal heart regeneration
    • Aurora, A. B. et al. Macrophages are required for neonatal heart regeneration. J. Clin. Invest. 124, 1382-1392 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 1382-1392
    • Aurora, A.B.1
  • 84
    • 79952065525 scopus 로고    scopus 로고
    • Transient regenerative potential of the neonatal mouse heart
    • Porrello, E. R. et al. Transient regenerative potential of the neonatal mouse heart. Science 331, 1078-1080 (2011).
    • (2011) Science , vol.331 , pp. 1078-1080
    • Porrello, E.R.1
  • 85
    • 84909594606 scopus 로고    scopus 로고
    • Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
    • Lavine, K. et al. Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart. Proc. Natl Acad. Sci. 111, 16029-16034 (2014).
    • (2014) Proc. Natl Acad. Sci. , vol.111 , pp. 16029-16034
    • Lavine, K.1
  • 86
    • 33645501949 scopus 로고    scopus 로고
    • Neonatal innate immunity to infectious agents
    • Marodi, L. Neonatal innate immunity to infectious agents. Infect. Immun. 74, 1999-2006 (2006).
    • (2006) Infect. Immun. , vol.74 , pp. 1999-2006
    • Marodi, L.1
  • 87
    • 84889600900 scopus 로고    scopus 로고
    • Programmed cell senescence during mammalian embryonic development
    • Munoz-Espin, D. et al. Programmed cell senescence during mammalian embryonic development. Cell 155, 1104-1118 (2013).
    • (2013) Cell , vol.155 , pp. 1104-1118
    • Munoz-Espin, D.1
  • 88
    • 84889565689 scopus 로고    scopus 로고
    • Senescence is a developmental mechanism that contributes to embryonic growth and patterning
    • Storer, M. et al. Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell 155, 1119-1130 (2013).
    • (2013) Cell , vol.155 , pp. 1119-1130
    • Storer, M.1
  • 89
    • 84885318684 scopus 로고    scopus 로고
    • Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction
    • Wan, E. et al. Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction. Circ. Res. 113, 1004-1012 (2013).
    • (2013) Circ. Res. , vol.113 , pp. 1004-1012
    • Wan, E.1
  • 90
    • 84867740805 scopus 로고    scopus 로고
    • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
    • Gautier, E. L. et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nature Immunol. 13, 1118-1128 (2012).
    • (2012) Nature Immunol. , vol.13 , pp. 1118-1128
    • Gautier, E.L.1
  • 91
    • 84881356321 scopus 로고    scopus 로고
    • AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
    • Mounier, R. et al. AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration. Cell. Metab. 18, 251-264 (2013).
    • (2013) Cell. Metab. , vol.18 , pp. 251-264
    • Mounier, R.1
  • 92
    • 34248997759 scopus 로고    scopus 로고
    • Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    • Arnold, L. et al. Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J. Exp. Med. 204, 1057-1069 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1057-1069
    • Arnold, L.1
  • 93
    • 84859432016 scopus 로고    scopus 로고
    • + T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice
    • + T lymphocytes improves wound healing and survival after experimental myocardial infarction in mice. Circulation 125, 1652-1663 (2012).
    • (2012) Circulation , vol.125 , pp. 1652-1663
    • Hofmann, U.1
  • 94
    • 84255169303 scopus 로고    scopus 로고
    • Regulatory T lymphocytes attenuate myocardial infarction-induced ventricular remodeling in mice
    • Matsumoto, K. et al. Regulatory T lymphocytes attenuate myocardial infarction-induced ventricular remodeling in mice. Int. Heart J. 52, 382-387 (2011).
    • (2011) Int. Heart J. , vol.52 , pp. 382-387
    • Matsumoto, K.1
  • 95
    • 77952065445 scopus 로고    scopus 로고
    • CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells
    • Dobaczewski, M., Xia, Y., Bujak, M., Gonzalez-Quesada, C. & Frangogiannis, N. G. CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. Am. J. Pathol. 176, 2177-2187 (2010).
    • (2010) Am. J. Pathol. , vol.176 , pp. 2177-2187
    • Dobaczewski, M.1    Xia, Y.2    Bujak, M.3    Gonzalez-Quesada, C.4    Frangogiannis, N.G.5
  • 96
    • 33750701819 scopus 로고    scopus 로고
    • + T lymphocytes
    • + T lymphocytes. Circulation 114, 2056-2064 (2006).
    • (2006) Circulation , vol.114 , pp. 2056-2064
    • Yang, Z.1
  • 97
    • 36849050907 scopus 로고    scopus 로고
    • Protective mechanisms of IVIG
    • Clynes, R. Protective mechanisms of IVIG. Curr. Opin. Immunol. 19, 646-651 (2007).
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 646-651
    • Clynes, R.1
  • 98
    • 78650658230 scopus 로고    scopus 로고
    • + T cell population in response to ischemic heart injury
    • + T cell population in response to ischemic heart injury. J. Immunol. 185, 6286-6293 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 6286-6293
    • Curato, C.1
  • 99
    • 58149375072 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor stimulation: A novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?
    • Kaschina, E. et al. Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction? Circulation 118, 2523-2532 (2008).
    • (2008) Circulation , vol.118 , pp. 2523-2532
    • Kaschina, E.1
  • 100
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • Cohn, J. N. & Tognoni, G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N. Engl. J. Med. 345, 1667-1675 (2001).
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 101
    • 0037036971 scopus 로고    scopus 로고
    • Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: The OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan
    • Dickstein, K. & Kjekshus, J. Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan. Lancet 360, 752-760 (2002).
    • (2002) Lancet , vol.360 , pp. 752-760
    • Dickstein, K.1    Kjekshus, J.2
  • 102
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
    • Mehta, P. K. & Griendling, K. K. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am. J. Physiol. Cell Physiol. 292, C82-C97 (2007).
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292 , pp. C82-C97
    • Mehta, P.K.1    Griendling, K.K.2
  • 103
    • 78650660392 scopus 로고    scopus 로고
    • Induction of cardiac angiogenesis requires killer cell lectin-like receptor 1 and α4β7 integrin expression by NK cells
    • Bouchentouf, M. et al. Induction of cardiac angiogenesis requires killer cell lectin-like receptor 1 and α4β7 integrin expression by NK cells. J. Immunol. 185, 7014-7025 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 7014-7025
    • Bouchentouf, M.1
  • 104
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF
    • Fadok, V. A. et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J. Clin. Invest. 101, 890-898 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 890-898
    • Fadok, V.A.1
  • 105
    • 0031454570 scopus 로고    scopus 로고
    • Immunosuppressive effects of apoptotic cells
    • Voll, R. E. et al. Immunosuppressive effects of apoptotic cells. Nature 390, 350-351 (1997).
    • (1997) Nature , vol.390 , pp. 350-351
    • Voll, R.E.1
  • 106
    • 84894102230 scopus 로고    scopus 로고
    • Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
    • Xue, J. et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40, 274-288 (2014).
    • (2014) Immunity , vol.40 , pp. 274-288
    • Xue, J.1
  • 107
    • 15244344110 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
    • Stark, M. A. et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22, 285-294 (2005).
    • (2005) Immunity , vol.22 , pp. 285-294
    • Stark, M.A.1
  • 108
    • 53949089841 scopus 로고    scopus 로고
    • IL-17F/IL-17R interaction stimulates granulopoiesis in mice
    • Tan, W. et al. IL-17F/IL-17R interaction stimulates granulopoiesis in mice. Exp. Hematol. 36, 1417-1427 (2008).
    • (2008) Exp. Hematol. , vol.36 , pp. 1417-1427
    • Tan, W.1
  • 109
    • 0034193959 scopus 로고    scopus 로고
    • Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis
    • Schwarzenberger, P. et al. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J. Immunol. 164, 4783-4789 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 4783-4789
    • Schwarzenberger, P.1
  • 110
    • 84880544110 scopus 로고    scopus 로고
    • Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction
    • Yan, X. et al. Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction. J. Am. Heart Assoc. 1, e004408 (2012).
    • (2012) J. Am. Heart Assoc. , vol.1 , pp. e004408
    • Yan, X.1
  • 111
    • 84862912958 scopus 로고    scopus 로고
    • Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration
    • Liao, Y. H. et al. Interleukin-17A contributes to myocardial ischemia/reperfusion injury by regulating cardiomyocyte apoptosis and neutrophil infiltration. J. Am. Coll. Cardiol. 59, 420-429 (2012).
    • (2012) J. Am. Coll. Cardiol. , vol.59 , pp. 420-429
    • Liao, Y.H.1
  • 112
    • 70350575289 scopus 로고    scopus 로고
    • IL-17 induces myocardial fibrosis and enhances RANKL/OPG and MMP/TIMP signaling in isoproterenol-induced heart failure
    • Feng, W. et al. IL-17 induces myocardial fibrosis and enhances RANKL/OPG and MMP/TIMP signaling in isoproterenol-induced heart failure. Exp. Mol. Pathol. 87, 212-218 (2009).
    • (2009) Exp. Mol. Pathol. , vol.87 , pp. 212-218
    • Feng, W.1
  • 113
    • 84896124089 scopus 로고    scopus 로고
    • Interleukin-23 deficiency leads to impaired wound healing and adverse prognosis after myocardial infarction
    • Savvatis, K. et al. Interleukin-23 deficiency leads to impaired wound healing and adverse prognosis after myocardial infarction. Circ. Heart Fail. 7, 161-171 (2014).
    • (2014) Circ. Heart Fail. , vol.7 , pp. 161-171
    • Savvatis, K.1
  • 114
    • 67651095943 scopus 로고    scopus 로고
    • Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation
    • Haudek, S. B. et al. Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation. Cardiovasc. Res. 83, 511-518 (2009).
    • (2009) Cardiovasc. Res. , vol.83 , pp. 511-518
    • Haudek, S.B.1
  • 115
    • 0035852766 scopus 로고    scopus 로고
    • Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy
    • Lim, D. S. et al. Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation 103, 789-791 (2001).
    • (2001) Circulation , vol.103 , pp. 789-791
    • Lim, D.S.1
  • 116
    • 79961072509 scopus 로고    scopus 로고
    • CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis
    • Xu, J. et al. CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis. Am. J. Physiol. Heart Circ. Physiol. 301, H538-H547 (2011).
    • (2011) Am. J. Physiol. Heart Circ. Physiol. , vol.301 , pp. H538-H547
    • Xu, J.1
  • 117
    • 77955270565 scopus 로고    scopus 로고
    • Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy
    • Haudek, S. B. et al. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J. Mol. Cell Cardiol. 49, 499-507 (2010).
    • (2010) J. Mol. Cell Cardiol. , vol.49 , pp. 499-507
    • Haudek, S.B.1
  • 118
    • 0027182438 scopus 로고
    • Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype
    • Sadoshima, J. & Izumo, S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype. Circ. Res. 73, 413-423 (1993).
    • (1993) Circ. Res. , vol.73 , pp. 413-423
    • Sadoshima, J.1    Izumo, S.2
  • 119
    • 84870255071 scopus 로고    scopus 로고
    • Interferon-γ signaling inhibition ameliorates angiotensin II-induced cardiac damage
    • Marko, L. et al. Interferon-γ signaling inhibition ameliorates angiotensin II-induced cardiac damage. Hypertension 60, 1430-1436 (2012).
    • (2012) Hypertension , vol.60 , pp. 1430-1436
    • Marko, L.1
  • 120
    • 84860439438 scopus 로고    scopus 로고
    • Reciprocal interaction between macrophages and T cells stimulates IFN-γ and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis
    • Han, Y. L. et al. Reciprocal interaction between macrophages and T cells stimulates IFN-γ and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis. PLoS ONE. 7, e35506 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e35506
    • Han, Y.L.1
  • 121
    • 84878201717 scopus 로고    scopus 로고
    • Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts
    • Crawford, J. R., Haudek, S. B., Cieslik, K. A., Trial, J. &Entman, M. L. Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts. J. Cardiovasc. Transl. Res. 5, 749-759 (2012).
    • (2012) J. Cardiovasc. Transl. Res. , vol.5 , pp. 749-759
    • Crawford, J.R.1    Haudek, S.B.2    Cieslik, K.A.3    Trial, J.4    Entman, M.L.5
  • 122
    • 77953024222 scopus 로고    scopus 로고
    • Chagas disease: 100 years after its discovery. A systemic review
    • Coura, J. R. & Borges-Pereira, J. Chagas disease: 100 years after its discovery. A systemic review. Acta Trop. 115, 5-13 (2010).
    • (2010) Acta Trop. , vol.115 , pp. 5-13
    • Coura, J.R.1    Borges-Pereira, J.2
  • 123
    • 84857308128 scopus 로고    scopus 로고
    • Update on myocarditis
    • Kindermann, I. et al. Update on myocarditis. J. Am. Coll. Cardiol. 59, 779-792 (2012).
    • (2012) J. Am. Coll. Cardiol. , vol.59 , pp. 779-792
    • Kindermann, I.1
  • 124
    • 0023587869 scopus 로고
    • Cardiac myosin induces myocarditis in genetically predisposed mice
    • Neu, N. et al. Cardiac myosin induces myocarditis in genetically predisposed mice. J. Immunol. 139, 3630-3636 (1987).
    • (1987) J. Immunol. , vol.139 , pp. 3630-3636
    • Neu, N.1
  • 126
    • 14044279226 scopus 로고    scopus 로고
    • High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction
    • Kuhl, U. et al. High prevalence of viral genomes and multiple viral infections in the myocardium of adults with "idiopathic" left ventricular dysfunction. Circulation 111, 887-893 (2005).
    • (2005) Circulation , vol.111 , pp. 887-893
    • Kuhl, U.1
  • 127
    • 0034713273 scopus 로고    scopus 로고
    • The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus
    • Martino, T. A. et al. The coxsackie-adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus. Virology 271, 99-108 (2000).
    • (2000) Virology , vol.271 , pp. 99-108
    • Martino, T.A.1
  • 128
    • 30344475861 scopus 로고    scopus 로고
    • Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions
    • Coyne, C. B. & Bergelson, J. M. Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell 124, 119-131 (2006).
    • (2006) Cell , vol.124 , pp. 119-131
    • Coyne, C.B.1    Bergelson, J.M.2
  • 129
    • 0033956327 scopus 로고    scopus 로고
    • Viral myocarditis: Receptors that bridge the cardiovascular with the immune system?
    • Liu, P. P. & Opavsky, M. A. Viral myocarditis: receptors that bridge the cardiovascular with the immune system? Circ. Res. 86, 253-254 (2000).
    • (2000) Circ. Res. , vol.86 , pp. 253-254
    • Liu, P.P.1    Opavsky, M.A.2
  • 130
    • 67651100871 scopus 로고    scopus 로고
    • Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis
    • Kallewaard, N. L. et al. Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis. Cell Host Microbe 6, 91-98 (2009).
    • (2009) Cell Host Microbe , vol.6 , pp. 91-98
    • Kallewaard, N.L.1
  • 131
    • 0033622010 scopus 로고    scopus 로고
    • The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease
    • Liu, P. et al. The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease. Nature Med. 6, 429-434 (2000).
    • (2000) Nature Med. , vol.6 , pp. 429-434
    • Liu, P.1
  • 132
    • 0035905767 scopus 로고    scopus 로고
    • CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
    • Irie-Sasaki, J. et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409, 349-354 (2001).
    • (2001) Nature , vol.409 , pp. 349-354
    • Irie-Sasaki, J.1
  • 133
    • 84884998660 scopus 로고    scopus 로고
    • + monocyte migration and impairing interferon production
    • + monocyte migration and impairing interferon production. Circulation 128, 1542-1554 (2013).
    • (2013) Circulation , vol.128 , pp. 1542-1554
    • Valaperti, A.1
  • 134
    • 77952621339 scopus 로고    scopus 로고
    • Myeloid differentiation factor-88 contributes to TLR9-mediated modulation of acute coxsackievirus B3-induced myocarditis in vivo
    • Riad, A. et al. Myeloid differentiation factor-88 contributes to TLR9-mediated modulation of acute coxsackievirus B3-induced myocarditis in vivo. Am. J. Physiol. Heart Circ. Physiol. 298, H2024-H2031 (2010).
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.298 , pp. H2024-H2031
    • Riad, A.1
  • 135
    • 26844546302 scopus 로고    scopus 로고
    • Myeloid differentiation factor-88 plays a crucial role in the pathogenesis of Coxsackievirus B3-induced myocarditis and influences type I interferon production
    • Fuse, K. et al. Myeloid differentiation factor-88 plays a crucial role in the pathogenesis of Coxsackievirus B3-induced myocarditis and influences type I interferon production. Circulation 112, 2276-2285 (2005).
    • (2005) Circulation , vol.112 , pp. 2276-2285
    • Fuse, K.1
  • 136
    • 77953773927 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance
    • Holm, G. H. et al. Interferon regulatory factor 3 attenuates reovirus myocarditis and contributes to viral clearance. J. Virol. 84, 6900-6908 (2010).
    • (2010) J. Virol. , vol.84 , pp. 6900-6908
    • Holm, G.H.1
  • 137
    • 0033578663 scopus 로고    scopus 로고
    • Susceptibility to myocarditis is dependent on the response of αβ T lymphocytes to coxsackieviral infection
    • Opavsky, M. A. et al. Susceptibility to myocarditis is dependent on the response of αβ T lymphocytes to coxsackieviral infection. Circ. Res. 85, 551-558 (1999).
    • (1999) Circ. Res. , vol.85 , pp. 551-558
    • Opavsky, M.A.1
  • 138
    • 77954086395 scopus 로고    scopus 로고
    • Regulatory T cells protect mice against coxsackievirus-induced myocarditis through the transforming growth factor β-coxsackie-adenovirus receptor pathway
    • Shi, Y. et al. Regulatory T cells protect mice against coxsackievirus-induced myocarditis through the transforming growth factor β-coxsackie-adenovirus receptor pathway. Circulation 121, 2624-2634 (2010).
    • (2010) Circulation , vol.121 , pp. 2624-2634
    • Shi, Y.1
  • 139
    • 0029024004 scopus 로고
    • A clinical trial of immunosuppressive therapy for myocarditis
    • The Myocarditis Treatment Trial Investigators
    • Mason, J. W. et al. A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators. N. Engl. J. Med. 333, 269-275 (1995).
    • (1995) N. Engl. J. Med. , vol.333 , pp. 269-275
    • Mason, J.W.1
  • 140
    • 0038120010 scopus 로고    scopus 로고
    • Interferon-β treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction
    • Kuhl, U. et al. Interferon-β treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction. Circulation 107, 2793-2798 (2003).
    • (2003) Circulation , vol.107 , pp. 2793-2798
    • Kuhl, U.1
  • 141
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • Poss, K. D., Wilson, L. G. & Keating, M. T. Heart regeneration in zebrafish. Science 298, 2188-2190 (2002).
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 142
    • 33845708407 scopus 로고    scopus 로고
    • Re-programming of newt cardiomyocytes is induced by tissue regeneration
    • Laube, F., Heister, M., Scholz, C., Borchardt, T. & Braun, T. Re-programming of newt cardiomyocytes is induced by tissue regeneration. J. Cell Sci. 119, 4719-4729 (2006).
    • (2006) J. Cell Sci. , vol.119 , pp. 4719-4729
    • Laube, F.1    Heister, M.2    Scholz, C.3    Borchardt, T.4    Braun, T.5
  • 143
    • 84878699191 scopus 로고    scopus 로고
    • Macrophages are required for adult salamander limb regeneration
    • Godwin, J. W., Pinto, A. R. & Rosenthal, N. A. Macrophages are required for adult salamander limb regeneration. Proc. Natl Acad. Sci. USA 110, 9415-9420 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 9415-9420
    • Godwin, J.W.1    Pinto, A.R.2    Rosenthal, N.A.3
  • 144
    • 84918534306 scopus 로고    scopus 로고
    • Evolution of innate immunity: Clues from invertebrates via fish to mammals
    • Buchmann, K. Evolution of innate immunity: clues from invertebrates via fish to mammals. Front. Immunol. 5, 459 (2014).
    • (2014) Front. Immunol. , vol.5 , pp. 459
    • Buchmann, K.1
  • 145
    • 84904401883 scopus 로고    scopus 로고
    • Origin and functions of tissue macrophages
    • Epelman, S., Lavine, K. J. & Randolph, G. J. Origin and functions of tissue macrophages. Immunity 41, 21-35 (2014).
    • (2014) Immunity , vol.41 , pp. 21-35
    • Epelman, S.1    Lavine, K.J.2    Randolph, G.J.3
  • 146
    • 0036092801 scopus 로고    scopus 로고
    • Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
    • Dai, X. M. et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 99, 111-120 (2002).
    • (2002) Blood , vol.99 , pp. 111-120
    • Dai, X.M.1
  • 147
    • 0242549003 scopus 로고    scopus 로고
    • Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
    • McKercher, S. R. et al. Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J. 15, 5647-5658 (1996).
    • (1996) EMBO J. , vol.15 , pp. 5647-5658
    • McKercher, S.R.1
  • 148
    • 0025323482 scopus 로고
    • Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse
    • Wiktor-Jedrzejczak, W. et al. Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proc. Natl Acad. Sci. USA 87, 4828-4832 (1990).
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 4828-4832
    • Wiktor-Jedrzejczak, W.1
  • 149
    • 79960997061 scopus 로고    scopus 로고
    • The interplay between macrophages and angiogenesis in development, tissue injury and regeneration
    • Nucera, S., Biziato, D. & De, P. M. The interplay between macrophages and angiogenesis in development, tissue injury and regeneration. Int. J. Dev. Biol. 55, 495-503 (2011).
    • (2011) Int. J. Dev. Biol. , vol.55 , pp. 495-503
    • Nucera, S.1    Biziato, D.2    De, P.M.3
  • 150
    • 77956273530 scopus 로고    scopus 로고
    • Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction
    • Fantin, A. et al. Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood 116, 829-840 (2010).
    • (2010) Blood , vol.116 , pp. 829-840
    • Fantin, A.1
  • 151
    • 84879873757 scopus 로고    scopus 로고
    • The importance of microglia in the development of the vasculature in the central nervous system
    • Arnold, T. & Betsholtz, C. The importance of microglia in the development of the vasculature in the central nervous system. Vasc. Cell 5, 4 (2013).
    • (2013) Vasc. Cell , vol.5 , pp. 4
    • Arnold, T.1    Betsholtz, C.2
  • 152
    • 25144451336 scopus 로고    scopus 로고
    • WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature
    • Lobov, I. B. et al. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature 437, 417-421 (2005).
    • (2005) Nature , vol.437 , pp. 417-421
    • Lobov, I.B.1
  • 153
    • 84900331122 scopus 로고    scopus 로고
    • A proliferative burst during preadolescence establishes the final cardiomyocyte number
    • Naqvi, N. et al. A proliferative burst during preadolescence establishes the final cardiomyocyte number. Cell 157, 795-807 (2014).
    • (2014) Cell , vol.157 , pp. 795-807
    • Naqvi, N.1
  • 154
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann, O. et al. Evidence for cardiomyocyte renewal in humans. Science 324, 98-102 (2009).
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1


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