메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κ B pathway

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN A20; RNA BINDING PROTEIN; ROQUIN PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; NFKBIA PROTEIN, HUMAN; NUCLEAR PROTEIN; RC3H1 PROTEIN, HUMAN; SIGNAL PEPTIDE; TNFAIP3 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; UBIQUITIN PROTEIN LIGASE;

EID: 84937047445     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8367     Document Type: Article
Times cited : (91)

References (58)
  • 1
    • 84858446718 scopus 로고    scopus 로고
    • Regulation of cytoplasmic mRNA decay
    • Schoenberg, D.R. , Maquat, L.E. Regulation of cytoplasmic mRNA decay. Nat. Rev. Genet. 13, 246-259 (2012).
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 246-259
    • Schoenberg, D.R.1    Maquat, L.E.2
  • 2
    • 60749124122 scopus 로고    scopus 로고
    • The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
    • Hao, S. , Baltimore, D. The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat. Immunol. 10, 281-288 (2009).
    • (2009) Nat. Immunol. , vol.10 , pp. 281-288
    • Hao, S.1    Baltimore, D.2
  • 3
    • 21144438325 scopus 로고    scopus 로고
    • A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
    • Vinuesa, C.G. et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 435, 452-458 (2005).
    • (2005) Nature , vol.435 , pp. 452-458
    • Vinuesa, C.G.1
  • 4
    • 77951237059 scopus 로고    scopus 로고
    • The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs
    • Athanasopoulos, V. et al. The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs. FEBS J. 277, 2109-2127 (2010).
    • (2010) FEBS J. , vol.277 , pp. 2109-2127
    • Athanasopoulos, V.1
  • 5
    • 84876775237 scopus 로고    scopus 로고
    • Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation
    • Pratama, A. et al. Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity 38, 669-680 (2013).
    • (2013) Immunity , vol.38 , pp. 669-680
    • Pratama, A.1
  • 6
    • 36048946330 scopus 로고    scopus 로고
    • Roquin represses autoimmunity by limiting inducible T-cell costimulator messenger RNA
    • Yu, D. et al. Roquin represses autoimmunity by limiting inducible T-cell costimulator messenger RNA. Nature 450, 299-303 (2007).
    • (2007) Nature , vol.450 , pp. 299-303
    • Yu, D.1
  • 7
    • 77954959530 scopus 로고    scopus 로고
    • Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
    • Glasmacher, E. et al. Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression. Nat. Immunol. 11, 725-733 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 725-733
    • Glasmacher, E.1
  • 8
    • 84876781274 scopus 로고    scopus 로고
    • Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation
    • Vogel, K.U. et al. Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. Immunity 38, 655-668 (2013).
    • (2013) Immunity , vol.38 , pp. 655-668
    • Vogel, K.U.1
  • 9
    • 84877708543 scopus 로고    scopus 로고
    • Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs
    • Leppek, K., Schott, J., Reitter, S., Poetz, F., Hammond, M.C. , Stoecklin, G. Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs. Cell 153, 869-881 (2013).
    • (2013) Cell , vol.153 , pp. 869-881
    • Leppek, K.1    Schott, J.2    Reitter, S.3    Poetz, F.4    Hammond, M.C.5    Stoecklin, G.6
  • 10
    • 84905656367 scopus 로고    scopus 로고
    • Structural basis for RNA recognition in roquinmediated post-transcriptional gene regulation
    • Schlundt, A. et al. Structural basis for RNA recognition in roquinmediated post-transcriptional gene regulation. Nat. Struct. Mol. Biol. 21, 671-678 (2014).
    • (2014) Nat. Struct. Mol. Biol. , vol.21 , pp. 671-678
    • Schlundt, A.1
  • 11
    • 84905645339 scopus 로고    scopus 로고
    • The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA
    • Tan, D., Zhou, M., Kiledjian, M. , Tong, L. The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. Nat. Struct. Mol. Biol. 21, 679-685 (2014).
    • (2014) Nat. Struct. Mol. Biol. , vol.21 , pp. 679-685
    • Tan, D.1    Zhou, M.2    Kiledjian, M.3    Tong, L.4
  • 13
    • 84893134469 scopus 로고    scopus 로고
    • Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses
    • Maruyama, T. et al. Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses. Sci. Signal. 7, ra8 (2014).
    • (2014) Sci. Signal. , vol.7 , pp. 8
    • Maruyama, T.1
  • 14
    • 84877793134 scopus 로고    scopus 로고
    • Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action
    • Brooks, S.A. , Blackshear, P.J. Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim. Biophys. Acta 1829, 666-679 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1829 , pp. 666-679
    • Brooks, S.A.1    Blackshear, P.J.2
  • 15
    • 84892172028 scopus 로고    scopus 로고
    • Global target mRNA specification and regulation by the RNA-binding protein ZFP36
    • Mukherjee, N. et al. Global target mRNA specification and regulation by the RNA-binding protein ZFP36. Genome Biol. 15, R12 (2014).
    • (2014) Genome Biol , vol.15 , pp. 12
    • Mukherjee, N.1
  • 16
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw, G. , Kamen, R. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46, 659-667 (1986).
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 17
    • 0000370303 scopus 로고
    • Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
    • Caput, D., Beutler, B., Hartog, K., Thayer, R., Brown-Shimer, S. , Cerami, A. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl Acad. Sci. USA 83, 1670-1674 (1986).
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 1670-1674
    • Caput, D.1    Beutler, B.2    Hartog, K.3    Thayer, R.4    Brown-Shimer, S.5    Cerami, A.6
  • 18
    • 0028788194 scopus 로고
    • AU-rich elements: Characterization and importance in mRNA degradation
    • Chen, C.Y. , Shyu, A.B. AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem. Sci. 20, 465-470 (1995).
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 465-470
    • Chen, C.Y.1    Shyu, A.B.2
  • 19
    • 77950920903 scopus 로고    scopus 로고
    • Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
    • Hafner, M. et al. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141, 129-141 (2010).
    • (2010) Cell , vol.141 , pp. 129-141
    • Hafner, M.1
  • 20
    • 84858120447 scopus 로고    scopus 로고
    • Regulation of NF-kappaB signaling by the A20 deubiquitinase
    • Shembade, N. , Harhaj, E.W. Regulation of NF-kappaB signaling by the A20 deubiquitinase. Cell. Mol. Immunol. 9, 123-130 (2012).
    • (2012) Cell. Mol. Immunol. , vol.9 , pp. 123-130
    • Shembade, N.1    Harhaj, E.W.2
  • 21
    • 84867898782 scopus 로고    scopus 로고
    • A20: Linking a complex regulator of ubiquitylation to immunity and human disease
    • Ma, A. , Malynn, B.A. A20: linking a complex regulator of ubiquitylation to immunity and human disease. Nat. Rev. Immunol. 12, 774-785 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 774-785
    • Ma, A.1    Malynn, B.A.2
  • 22
    • 79960929333 scopus 로고    scopus 로고
    • Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR
    • Lebedeva, S. et al. Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. Mol. Cell 43, 340-352 (2011).
    • (2011) Mol. Cell , vol.43 , pp. 340-352
    • Lebedeva, S.1
  • 24
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology
    • Ashburner, M. et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25, 25-29 (2000).
    • (2000) The Gene Ontology Consortium. Nat. Genet. , vol.25 , pp. 25-29
    • Ashburner, M.1
  • 25
    • 84863515320 scopus 로고    scopus 로고
    • GraphClust: Alignment-free structural clustering of local RNA secondary structures
    • Heyne, S., Costa, F., Rose, D. , Backofen, R. GraphClust: alignment-free structural clustering of local RNA secondary structures. Bioinformatics 28, i224-i232 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 1224-1232
    • Heyne, S.1    Costa, F.2    Rose, D.3    Backofen, R.4
  • 26
    • 84859947721 scopus 로고    scopus 로고
    • LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs
    • Will, S., Joshi, T., Hofacker, I.L., Stadler, P.F. , Backofen, R. LocARNA-P: accurate boundary prediction and improved detection of structural RNAs. RNA 18, 900-914 (2012).
    • (2012) RNA , vol.18 , pp. 900-914
    • Will, S.1    Joshi, T.2    Hofacker, I.L.3    Stadler, P.F.4    Backofen, R.5
  • 27
    • 34247598415 scopus 로고    scopus 로고
    • Inferring noncoding RNA families and classes by means of genome-scale structure-based clustering
    • Will, S., Reiche, K., Hofacker, I.L., Stadler, P.F. , Backofen, R. Inferring noncoding RNA families and classes by means of genome-scale structure-based clustering. PLoS Comput. Biol. 3, e65 (2007).
    • (2007) PLoS Comput. Biol. , vol.3 , pp. e65
    • Will, S.1    Reiche, K.2    Hofacker, I.L.3    Stadler, P.F.4    Backofen, R.5
  • 28
    • 32544452741 scopus 로고    scopus 로고
    • CMfinder - A covariance model based RNA motif finding algorithm
    • Yao, Z., Weinberg, Z. , Ruzzo, W.L. CMfinder-a covariance model based RNA motif finding algorithm. Bioinformatics 22, 445-452 (2006).
    • (2006) Bioinformatics , vol.22 , pp. 445-452
    • Yao, Z.1    Weinberg, Z.2    Ruzzo, W.L.3
  • 29
    • 65549111754 scopus 로고    scopus 로고
    • Infernal 1.0: Inference of RNA alignments
    • Nawrocki, E.P., Kolbe, D.L. , Eddy, S.R. Infernal 1.0: inference of RNA alignments. Bioinformatics 25, 1335-1337 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1335-1337
    • Nawrocki, E.P.1    Kolbe, D.L.2    Eddy, S.R.3
  • 30
    • 0037326081 scopus 로고    scopus 로고
    • Mass spectrometric-based approaches in quantitative proteomics
    • Ong, S.E., Foster, L.J. , Mann, M. Mass spectrometric-based approaches in quantitative proteomics. Methods 29, 124-130 (2003).
    • (2003) Methods , vol.29 , pp. 124-130
    • Ong, S.E.1    Foster, L.J.2    Mann, M.3
  • 31
    • 84864383679 scopus 로고    scopus 로고
    • Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex
    • Doidge, R., Mittal, S., Aslam, A. , Winkler, G.S. Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex. Biochem. Soc. Trans. 40, 896-901 (2012).
    • (2012) Biochem. Soc. Trans. , vol.40 , pp. 896-901
    • Doidge, R.1    Mittal, S.2    Aslam, A.3    Winkler, G.S.4
  • 32
    • 50649118115 scopus 로고    scopus 로고
    • High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay
    • Dolken, L. et al. High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA 14, 1959-1972 (2008).
    • (2008) RNA , vol.14 , pp. 1959-1972
    • Dolken, L.1
  • 34
    • 0038444122 scopus 로고    scopus 로고
    • Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells
    • Elkon, R., Linhart, C., Sharan, R., Shamir, R. , Shiloh, Y. Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells. Genome Res. 13, 773-780 (2003).
    • (2003) Genome Res , vol.13 , pp. 773-780
    • Elkon, R.1    Linhart, C.2    Sharan, R.3    Shamir, R.4    Shiloh, Y.5
  • 35
    • 84877757564 scopus 로고    scopus 로고
    • Molecular basis of NF-kappaB signaling
    • Napetschnig, J. , Wu, H. Molecular basis of NF-kappaB signaling. Ann. Rev. Biophys. 42, 443-468 (2013).
    • (2013) Ann. Rev. Biophys. , vol.42 , pp. 443-468
    • Napetschnig, J.1    Wu, H.2
  • 36
    • 0344305376 scopus 로고    scopus 로고
    • Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
    • Huang, T.T., Wuerzberger-Davis, S.M., Wu, Z.H. , Miyamoto, S. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115, 565-576 (2003).
    • (2003) Cell , vol.115 , pp. 565-576
    • Huang, T.T.1    Wuerzberger-Davis, S.M.2    Wu, Z.H.3    Miyamoto, S.4
  • 37
    • 84863696106 scopus 로고    scopus 로고
    • Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFkappaB responses
    • Grimley, R. et al. Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFkappaB responses. PLoS ONE 7, e39847 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e39847
    • Grimley, R.1
  • 38
    • 62849118323 scopus 로고    scopus 로고
    • Autoregulatory feedback loops terminating the NF-kappaB response
    • Renner, F. , Schmitz, M.L. Autoregulatory feedback loops terminating the NF-kappaB response. Trends Biochem. Sci. 34, 128-135 (2009).
    • (2009) Trends Biochem. Sci. , vol.34 , pp. 128-135
    • Renner, F.1    Schmitz, M.L.2
  • 39
    • 84856641109 scopus 로고    scopus 로고
    • NF-kappaB the first quarter century: Remarkable progress and outstanding questions
    • Hayden, M.S. , Ghosh, S. NF-kappaB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 26, 203-234 (2012).
    • (2012) Genes Dev , vol.26 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 40
    • 84894534156 scopus 로고    scopus 로고
    • The IkappaB kinase complex in NF-kappaB regulation and beyond
    • Hinz, M. , Scheidereit, C. The IkappaB kinase complex in NF-kappaB regulation and beyond. EMBO Rep. 15, 46-61 (2014).
    • (2014) EMBO Rep , vol.15 , pp. 46-61
    • Hinz, M.1    Scheidereit, C.2
  • 41
    • 84880427394 scopus 로고    scopus 로고
    • A compendium of RNA-binding motifs for decoding gene regulation
    • Ray, D. et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature 499, 172-177 (2013).
    • (2013) Nature , vol.499 , pp. 172-177
    • Ray, D.1
  • 42
    • 80054842844 scopus 로고    scopus 로고
    • Loss of Roquin induces early death and immune deregulation but not autoimmunity
    • Bertossi, A. et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J. Exp. Med. 208, 1749-1756 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 1749-1756
    • Bertossi, A.1
  • 43
    • 84905562455 scopus 로고    scopus 로고
    • Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
    • Walle, L.V. et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature 512, 69-73 (2014).
    • (2014) Nature , vol.512 , pp. 69-73
    • Walle, L.V.1
  • 44
    • 84861997955 scopus 로고    scopus 로고
    • The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
    • Baltz, A.G. et al. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46, 674-690 (2012).
    • (2012) Mol. Cell , vol.46 , pp. 674-690
    • Baltz, A.G.1
  • 45
    • 59449085150 scopus 로고    scopus 로고
    • Global analysis of cellular protein translation by pulsed SILAC
    • Schwanhausser, B., Gossen, M., Dittmar, G. , Selbach, M. Global analysis of cellular protein translation by pulsed SILAC. Proteomics 9, 205-209 (2009).
    • (2009) Proteomics , vol.9 , pp. 205-209
    • Schwanhausser, B.1    Gossen, M.2    Dittmar, G.3    Selbach, M.4
  • 46
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., Sherman, B.T. , Lempicki, R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 47
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da, W., Sherman, B.T. , Lempicki, R.A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 37, 1-13 (2009).
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 48
    • 75549083389 scopus 로고    scopus 로고
    • UTRdb and UTRsite (RELEASE 2010): A collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs
    • Grillo, G. et al. UTRdb and UTRsite (RELEASE 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs. Nucleic Acids Res. 38, D75-D80 (2010).
    • (2010) Nucleic Acids Res , vol.38 , pp. D75-D80
    • Grillo, G.1
  • 49
  • 50
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips for matrixassisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Rappsilber, J., Ishihama, Y. , Mann, M. Stop and go extraction tips for matrixassisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 75, 663-670 (2003).
    • (2003) Anal. Chem. , vol.75 , pp. 663-670
    • Rappsilber, J.1    Ishihama, Y.2    Mann, M.3
  • 52
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim, D., Pertea, G., Trapnell, C., Pimentel, H., Kelley, R. , Salzberg, S.L. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
    • (2013) Genome Biol. , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 53
    • 84929144040 scopus 로고    scopus 로고
    • QuasR: Quantification and annotation of short reads in R
    • Gaidatzis, D., Lerch, A., Hahne, F. , Stadler, M.B. QuasR: quantification and annotation of short reads in R. Bioinformatics 31, 1130-1132 (2014).
    • (2014) Bioinformatics , vol.31 , pp. 1130-1132
    • Gaidatzis, D.1    Lerch, A.2    Hahne, F.3    Stadler, M.B.4
  • 55
    • 84934441299 scopus 로고    scopus 로고
    • Quantitative analysis of protein-RNA interactions by gel mobility shift
    • Ryder, S.P., Recht, M.I. , Williamson, J.R. Quantitative analysis of protein-RNA interactions by gel mobility shift. Methods Mol. Biol. 488, 99-115 (2008).
    • (2008) Methods Mol. Biol. , vol.488 , pp. 99-115
    • Ryder, S.P.1    Recht, M.I.2    Williamson, J.R.3
  • 56
    • 77957333810 scopus 로고    scopus 로고
    • A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
    • Hinz, M., Stilmann, M., Arslan, S.C., Khanna, K.K., Dittmar, G. , Scheidereit, C. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation. Mol. Cell 40, 63-74 (2010).
    • (2010) Mol. Cell , vol.40 , pp. 63-74
    • Hinz, M.1    Stilmann, M.2    Arslan, S.C.3    Khanna, K.K.4    Dittmar, G.5    Scheidereit, C.6
  • 57
    • 1342288026 scopus 로고    scopus 로고
    • Affy-analysis of Affymetrix GeneChip data at the probe level
    • Gautier, L., Cope, L., Bolstad, B.M. , Irizarry, R.A. affy-analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20, 307-315 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 58
    • 84884755942 scopus 로고    scopus 로고
    • Lessons learned from quantitative dynamical modeling in systems biology
    • Raue, A. et al. Lessons learned from quantitative dynamical modeling in systems biology. PLoS ONE 8, e74335 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e74335
    • Raue, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.