Hyperactivity of newborn pten knock-out neurons results from increased excitatory synaptic drive

Journal of Neuroscience

Volumn 35, Issue 3, 2015, Pages 943-959

  Williams, Michael R ^a   De Spenza, Tyrone ^a   Li, Meijie ^a   Gulledge, Allan T ^a   Luikart, Bryan W ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Autism spectrum disorder; Dendritic spine; Neuron structure function; Pten; Seizure; Synaptogenesis

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; ENHANCED GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN C FOS; PROTEIN S6;

ACTION POTENTIAL; AFTERHYPERPOLARIZATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; HYPERACTIVITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; MULTIPHOTON MICROSCOPY; NERVE EXCITABILITY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPIKE WAVE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; SEIZURE; SYNAPSE;

ACTION POTENTIALS; ANIMALS; DENTATE GYRUS; EXCITATORY POSTSYNAPTIC POTENTIALS; MICE, KNOCKOUT; NEURONS; PTEN PHOSPHOHYDROLASE; SEIZURES; SYNAPSES;

EID: 84921522339     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3144-14.2015     Document Type: Article

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