Human iPS cell-derived neurons uncover the impact of increased ras signaling in costello syndrome

Journal of Neuroscience

Volumn 36, Issue 1, 2016, Pages 142-152

  Rooney, Gemma E ^a   Goodwin, Alice F ^b   Depeille, Philippe ^b   Sharir, Amnon ^b   Schofield, Claude M ^a   Yeh, Erika ^b   Roose, Jeroen P ^b   Klein, Ophir D ^b   Rauen, Katherine A ^a,c   Weiss, Lauren A ^b   Ullian, Erik M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cortical development; Costello syndrome; IPS cells; Ras; Stem cells

Indexed keywords

ADULT; ARTICLE; BRAIN CORTEX LAYER; CELL CULTURE; COSTELLO SYNDROME; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORPHOLOGICAL ADAPTATION; NERVE CELL DIFFERENTIATION; ONCOGENE RAS; PLURIPOTENT STEM CELL; POINT MUTATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADOLESCENT; CELL DIFFERENTIATION; CHILD; INDUCED PLURIPOTENT STEM CELL; INFANT; METABOLISM; NEURAL STEM CELL; PATHOLOGY; PRESCHOOL CHILD; UPREGULATION;

RAS PROTEIN;

ADOLESCENT; ADULT; CELL DIFFERENTIATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COSTELLO SYNDROME; FEMALE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT; MALE; MIDDLE AGED; NEURAL STEM CELLS; RAS PROTEINS; UP-REGULATION;

EID: 84953713062     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1547-15.2016     Document Type: Article

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