Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

Orphanet Journal of Rare Diseases

Volumn 8, Issue 1, 2013, Pages

  Matsumoto, Yoshihisa ^a,b,c   Hayashi, Yohei ^d   Schlieve, Christopher R ^d,e,f   Ikeya, Makoto ^b   Kim, Hannah ^f   Nguyen, Trieu D ^d   Sami, Salma ^d   Baba, Shiro ^d   Barruet, Emilie ^f   Nasu, Akira ^a,b,g   Asaka, Isao ^b   Otsuka, Takanobu ^c   Yamanaka, Shinya ^b,d   Conklin, Bruce R ^d,h   Toguchida, Junya ^a,b,g   Hsiao, Edward C ^d,f  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^e DUKE NUS MEDICAL SCHOOL   (Singapore)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g KYOTO UNIVERSITY   (Japan)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Disease model in a dish; Endochondral ossification; Fibrodysplasia ossificans progressiva; FOP; Induced pluripotent stem cells

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN;

ARTICLE; BONE MINERALIZATION; CARTILAGE; CELL CULTURE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; EMBRYOID BODY; EMBRYONIC STEM CELL; ENCHONDRAL OSSIFICATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STEM CELL; OSSIFICATION; OSSIFYING MYOSITIS; PHENOTYPE; PLURIPOTENT STEM CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CARTILAGE CELL; CYTOLOGY; MALE; METABOLISM; MOUSE; PATHOLOGY; SCID MOUSE;

ANIMALS; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, SCID; MYOSITIS OSSIFICANS; OSTEOGENESIS;

EID: 84889876122     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/1750-1172-8-190     Document Type: Article

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