Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Martin Malpartida, Pau ^a   Batet, Marta ^a   Kaczmarska, Zuzanna ^b   Freier, Regina ^a   Gomes, Tiago ^a   Aragón, Eric ^a   Zou, Yilong ^c,d,f   Wang, Qiong ^c   Xi, Qiaoran ^c,g   Ruiz, Lidia ^a   Vea, Angela ^a   Márquez, José A ^b   Massagué, Joan ^c   Macias, Maria J ^a,e  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d Gerstner Sloan Kettering Graduate School of Biomedical Sciences   (United States)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; DOUBLE STRANDED DNA; HYDROGEN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; BONE MORPHOGENETIC PROTEIN; GOOSECOID PROTEIN; GSC PROTEIN, HUMAN; PROTEIN BINDING; SMAD3 PROTEIN, HUMAN; SMAD4 PROTEIN, HUMAN;

CELLS AND CELL COMPONENTS; CYTOGENETICS; GENE; GENOME; IMMUNOASSAY; PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CHROMOSOME 12; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA BASE COMPOSITION; DNA BINDING; DNA SEQUENCE; DNA STRAND; EMBRYO; ENHANCER REGION; HUMAN; HYDROGEN BOND; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PROMOTER REGION; ALLOSTERISM; ANIMAL; CELL LINEAGE; CHEMISTRY; CRISPR CAS SYSTEM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE EMBRYONIC STEM CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN MOTIF; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; AMINO ACID MOTIFS; ANIMALS; BINDING SITES; BONE MORPHOGENETIC PROTEINS; CELL LINEAGE; CRISPR-CAS SYSTEMS; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GOOSECOID PROTEIN; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOUSE EMBRYONIC STEM CELLS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 85037722974     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02054-6     Document Type: Article

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