Features of a Smad3 MH1-DNA complex: Roles of water and zinc in DNA binding

Journal of Biological Chemistry

Volumn 278, Issue 22, 2003, Pages 20327-20331

  Chai, Jijie ^a   Wu, Jia Wei ^a   Yan, Nieng ^a   Massagué, Joan ^b   Pavletich, Nikola P ^b   Shi, Yigong ^a  

^a PRINCETON UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; GENES; HYDROGEN BONDS; PROTEINS; WATER; ZINC;

LIGAND-RESPONSE GENES;

DNA;

CYSTEINE; DNA; DNA BASE; HISTIDINE; PALINDROMIC DNA; SMAD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; WATER; ZINC; DNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; BETA SHEET; BINDING AFFINITY; CRYSTAL STRUCTURE; DNA SEQUENCE; GENE EXPRESSION REGULATION; HUMAN; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SMAD3 PROTEIN; TRANS-ACTIVATORS; WATER; ZINC;

EID: 0038820062     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300134200     Document Type: Article

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