메뉴 건너뛰기




Volumn 63, Issue , 2018, Pages 12-21

Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain

Author keywords

Alzheimer's disease; Laser capture; Microglia; Parkinson's disease; RNA sequencing; Synapse; Virus

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD68 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPATITIS B CORE ANTIBODY; MICROTUBULE ASSOCIATED PROTEIN 2; MUSCARINIC M1 RECEPTOR; SYNAPTOPHYSIN;

EID: 85035754566     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2017.10.019     Document Type: Article
Times cited : (56)

References (70)
  • 3
    • 0029812139 scopus 로고    scopus 로고
    • On the relationship between measles virus and Alzheimer neurofibrillary tangles in subacute sclerosing panencephalitis
    • Bancher, C., Leitner, H., Jellinger, K., Eder, H., Setinek, U., Fischer, P., Wegiel, J., Wisniewski, H.M., On the relationship between measles virus and Alzheimer neurofibrillary tangles in subacute sclerosing panencephalitis. Neurobiol. Aging 17 (1996), 527–533.
    • (1996) Neurobiol. Aging , vol.17 , pp. 527-533
    • Bancher, C.1    Leitner, H.2    Jellinger, K.3    Eder, H.4    Setinek, U.5    Fischer, P.6    Wegiel, J.7    Wisniewski, H.M.8
  • 4
    • 84875262338 scopus 로고    scopus 로고
    • Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
    • Berchtold, N.C., Coleman, P.D., Cribbs, D.H., Rogers, J., Gillen, D.L., Cotman, C.W., Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease. Neurobiol. Aging 34 (2013), 1653–1661.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1653-1661
    • Berchtold, N.C.1    Coleman, P.D.2    Cribbs, D.H.3    Rogers, J.4    Gillen, D.L.5    Cotman, C.W.6
  • 6
    • 84902085333 scopus 로고    scopus 로고
    • Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease
    • Berchtold, N.C., Sabbagh, M.N., Beach, T.G., Kim, R.C., Cribbs, D.H., Cotman, C.W., Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease. Neurobiol. Aging 35 (2014), 1961–1972.
    • (2014) Neurobiol. Aging , vol.35 , pp. 1961-1972
    • Berchtold, N.C.1    Sabbagh, M.N.2    Beach, T.G.3    Kim, R.C.4    Cribbs, D.H.5    Cotman, C.W.6
  • 7
    • 0035667993 scopus 로고    scopus 로고
    • Churg-Strauss vasculitis with brain involvement following hepatitis B vaccination
    • Beretta, L., Caronni, M., Vanoli, M., Scorza, R., Churg-Strauss vasculitis with brain involvement following hepatitis B vaccination. Clin. Exp. Rheumatol., 19, 2001, 757.
    • (2001) Clin. Exp. Rheumatol. , vol.19 , pp. 757
    • Beretta, L.1    Caronni, M.2    Vanoli, M.3    Scorza, R.4
  • 8
    • 84872706357 scopus 로고    scopus 로고
    • Review: activation patterns of microglia and their identification in the human brain
    • Boche, D., Perry, V.H., Nicoll, J.A., Review: activation patterns of microglia and their identification in the human brain. Neuropathol. Appl. Neurobiol. 39 (2013), 3–18.
    • (2013) Neuropathol. Appl. Neurobiol. , vol.39 , pp. 3-18
    • Boche, D.1    Perry, V.H.2    Nicoll, J.A.3
  • 11
    • 58149464149 scopus 로고    scopus 로고
    • Brain metastases from hepatocellular carcinoma: prognostic factors and outcome: brain metastasis from HCC
    • Choi, H.J., Cho, B.C., Sohn, J.H., Shin, S.J., Kim, S.H., Kim, J.H., Yoo, N.C., Brain metastases from hepatocellular carcinoma: prognostic factors and outcome: brain metastasis from HCC. J. Neurooncol. 91 (2009), 307–313.
    • (2009) J. Neurooncol. , vol.91 , pp. 307-313
    • Choi, H.J.1    Cho, B.C.2    Sohn, J.H.3    Shin, S.J.4    Kim, S.H.5    Kim, J.H.6    Yoo, N.C.7
  • 18
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina, C., Aloisi, F., Meinl, E., Astrocytes are active players in cerebral innate immunity. Trends Immunol. 28 (2007), 138–145.
    • (2007) Trends Immunol. , vol.28 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 19
    • 84961226140 scopus 로고    scopus 로고
    • Microglia: Architects of the developing nervous system
    • Frost, J.L., Schafer, D.P., Microglia: Architects of the developing nervous system. Trends Cell. Biol. 26 (2016), 587–597.
    • (2016) Trends Cell. Biol. , vol.26 , pp. 587-597
    • Frost, J.L.1    Schafer, D.P.2
  • 20
    • 84958765684 scopus 로고    scopus 로고
    • Pyk2 is essential for astrocytes mobility following brain lesion
    • Giralt, A., Coura, R., Girault, J.A., Pyk2 is essential for astrocytes mobility following brain lesion. Glia 64 (2016), 620–634.
    • (2016) Glia , vol.64 , pp. 620-634
    • Giralt, A.1    Coura, R.2    Girault, J.A.3
  • 23
    • 4344644327 scopus 로고    scopus 로고
    • Herpes simplex virus type 1, apolipoprotein E and Alzheimer' disease
    • Itzhaki, R., Herpes simplex virus type 1, apolipoprotein E and Alzheimer' disease. Herpes 11 Suppl 2 (2004), 77A–82A.
    • (2004) Herpes , vol.11 Suppl 2 , pp. 77A-82A
    • Itzhaki, R.1
  • 24
    • 84906233113 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 and Alzheimer's disease: increasing evidence for a major role of the virus
    • Itzhaki, R.F., Herpes simplex virus type 1 and Alzheimer's disease: increasing evidence for a major role of the virus. Front. Aging Neurosci., 6, 2014, 202.
    • (2014) Front. Aging Neurosci. , vol.6 , pp. 202
    • Itzhaki, R.F.1
  • 27
    • 84957956929 scopus 로고    scopus 로고
    • Notch2 signaling promotes osteoclast resorption via activation of PYK2
    • Jin, W.J., Kim, B., Kim, J.W., Kim, H.H., Ha, H., Lee, Z.H., Notch2 signaling promotes osteoclast resorption via activation of PYK2. Cell Signal. 28 (2016), 357–365.
    • (2016) Cell Signal. , vol.28 , pp. 357-365
    • Jin, W.J.1    Kim, B.2    Kim, J.W.3    Kim, H.H.4    Ha, H.5    Lee, Z.H.6
  • 30
    • 84872176512 scopus 로고    scopus 로고
    • Microglia: new roles for the synaptic stripper
    • Kettenmann, H., Kirchhoff, F., Verkhratsky, A., Microglia: new roles for the synaptic stripper. Neuron 77 (2013), 10–18.
    • (2013) Neuron , vol.77 , pp. 10-18
    • Kettenmann, H.1    Kirchhoff, F.2    Verkhratsky, A.3
  • 31
    • 85035754118 scopus 로고    scopus 로고
    • Role of microglia in fungal infections of the central nervous system
    • Koutsouras, G.W., Ramos, R.L., Martinez, L.R., Role of microglia in fungal infections of the central nervous system. Virulence 8 (2016), 705–718.
    • (2016) Virulence , vol.8 , pp. 705-718
    • Koutsouras, G.W.1    Ramos, R.L.2    Martinez, L.R.3
  • 33
    • 0029791629 scopus 로고    scopus 로고
    • Neurotropic viruses and Alzheimer disease. Interaction of herpes simplex type 1 virus and apolipoprotein E in the etiology of the disease
    • Lin, W.R., Shang, D., Itzhaki, R.F., Neurotropic viruses and Alzheimer disease. Interaction of herpes simplex type 1 virus and apolipoprotein E in the etiology of the disease. Mol. Chem. Neuropathol. 28 (1996), 135–141.
    • (1996) Mol. Chem. Neuropathol. , vol.28 , pp. 135-141
    • Lin, W.R.1    Shang, D.2    Itzhaki, R.F.3
  • 37
    • 85050578606 scopus 로고    scopus 로고
    • Microglia and neurogenesis in the epileptic dentate gyrus
    • Luo, C., Ikegaya, Y., Koyama, R., Microglia and neurogenesis in the epileptic dentate gyrus. Neurogenesis (Austin), 3, 2016, e1235525.
    • (2016) Neurogenesis (Austin) , vol.3 , pp. e1235525
    • Luo, C.1    Ikegaya, Y.2    Koyama, R.3
  • 38
    • 0025303784 scopus 로고
    • Astrocytes and the plaques of Alzheimer's disease
    • Mandybur, T.I., Chuirazzi, C.C., Astrocytes and the plaques of Alzheimer's disease. Neurology 40 (1990), 635–639.
    • (1990) Neurology , vol.40 , pp. 635-639
    • Mandybur, T.I.1    Chuirazzi, C.C.2
  • 39
    • 81755181722 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 as risk factor associated to Alzheimer disease
    • Martin, C., Solis, L., Concha, M.I., Otth, C., Herpes simplex virus type 1 as risk factor associated to Alzheimer disease. Rev. Med. Chil. 139 (2011), 779–786.
    • (2011) Rev. Med. Chil. , vol.139 , pp. 779-786
    • Martin, C.1    Solis, L.2    Concha, M.I.3    Otth, C.4
  • 41
    • 85023160642 scopus 로고    scopus 로고
    • ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity
    • Mastroeni, D., Sekar, S., Nolz, J., Delvaux, E., Lunnon, K., Mill, J., Liang, W.S., Coleman, P.D., ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity. PLoS One, 12, 2017, e0177814.
    • (2017) PLoS One , vol.12 , pp. e0177814
    • Mastroeni, D.1    Sekar, S.2    Nolz, J.3    Delvaux, E.4    Lunnon, K.5    Mill, J.6    Liang, W.S.7    Coleman, P.D.8
  • 42
    • 84983373722 scopus 로고    scopus 로고
    • Subcellular localization of Pyk2 during oocyte fertilization and early-embryo development in mice
    • Meng, X.Q., Dai, Y.Y., Jing, L.D., Bai, J., Liu, S.Z., Zheng, K.G., Pan, J., Subcellular localization of Pyk2 during oocyte fertilization and early-embryo development in mice. J. Reprod. Dev. 62 (2016), 351–358.
    • (2016) J. Reprod. Dev. , vol.62 , pp. 351-358
    • Meng, X.Q.1    Dai, Y.Y.2    Jing, L.D.3    Bai, J.4    Liu, S.Z.5    Zheng, K.G.6    Pan, J.7
  • 45
    • 84864874844 scopus 로고    scopus 로고
    • Hippocampal neuronal loss in the CA1 and CA3 areas of Alzheimer's disease patients
    • Padurariu, M., Ciobica, A., Mavroudis, I., Fotiou, D., Baloyannis, S., Hippocampal neuronal loss in the CA1 and CA3 areas of Alzheimer's disease patients. Psychiatr. Danub. 24 (2012), 152–158.
    • (2012) Psychiatr. Danub. , vol.24 , pp. 152-158
    • Padurariu, M.1    Ciobica, A.2    Mavroudis, I.3    Fotiou, D.4    Baloyannis, S.5
  • 48
    • 78650063641 scopus 로고    scopus 로고
    • The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective
    • Perry, V.H., O'Connor, V., The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective. ASN Neuro., 2, 2010, e00047.
    • (2010) ASN Neuro. , vol.2 , pp. e00047
    • Perry, V.H.1    O'Connor, V.2
  • 51
    • 62549136124 scopus 로고    scopus 로고
    • Reactivation of hepatitis B: pathogenesis and clinical implications
    • Post, A., Nagendra, S., Reactivation of hepatitis B: pathogenesis and clinical implications. Curr. Infect. Dis. Rep. 11 (2009), 113–119.
    • (2009) Curr. Infect. Dis. Rep. , vol.11 , pp. 113-119
    • Post, A.1    Nagendra, S.2
  • 52
    • 66449130960 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the brain
    • Rivest, S., Regulation of innate immune responses in the brain. Nat. Rev. Immunol. 9 (2009), 429–439.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 429-439
    • Rivest, S.1
  • 54
    • 34547380204 scopus 로고    scopus 로고
    • Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?
    • Rogers, J., Mastroeni, D., Leonard, B., Joyce, J., Grover, A., Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?. Int. Rev. Neurobiol. 82 (2007), 235–246.
    • (2007) Int. Rev. Neurobiol. , vol.82 , pp. 235-246
    • Rogers, J.1    Mastroeni, D.2    Leonard, B.3    Joyce, J.4    Grover, A.5
  • 56
    • 84943279510 scopus 로고    scopus 로고
    • Microglia function in central nervous system development and plasticity
    • Schafer, D.P., Stevens, B., Microglia function in central nervous system development and plasticity. Cold Spring Harb. Perspect. Biol., 7, 2015, a020545.
    • (2015) Cold Spring Harb. Perspect. Biol. , vol.7 , pp. a020545
    • Schafer, D.P.1    Stevens, B.2
  • 57
    • 84893477702 scopus 로고    scopus 로고
    • Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone
    • Shigemoto-Mogami, Y., Hoshikawa, K., Goldman, J.E., Sekino, Y., Sato, K., Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone. J. Neurosci. 34 (2014), 2231–2243.
    • (2014) J. Neurosci. , vol.34 , pp. 2231-2243
    • Shigemoto-Mogami, Y.1    Hoshikawa, K.2    Goldman, J.E.3    Sekino, Y.4    Sato, K.5
  • 59
    • 84864134469 scopus 로고    scopus 로고
    • Microglia function in Alzheimer's disease
    • Solito, E., Sastre, M., Microglia function in Alzheimer's disease. Front. Pharmacol., 3, 2012, 14.
    • (2012) Front. Pharmacol. , vol.3 , pp. 14
    • Solito, E.1    Sastre, M.2
  • 60
    • 0001766394 scopus 로고
    • Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis
    • Stahl, S., MacKay, P., Magazin, M., Bruce, S.A., Murray, K., Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis. Proc. Natl. Acad. Sci. U. S. A. 79 (1982), 1606–1610.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 1606-1610
    • Stahl, S.1    MacKay, P.2    Magazin, M.3    Bruce, S.A.4    Murray, K.5
  • 62
    • 68949205705 scopus 로고    scopus 로고
    • Tumour necrosis factor modulation for treatment of Alzheimer's disease: rationale and current evidence
    • Tobinick, E., Tumour necrosis factor modulation for treatment of Alzheimer's disease: rationale and current evidence. CNS Drugs 23 (2009), 713–725.
    • (2009) CNS Drugs , vol.23 , pp. 713-725
    • Tobinick, E.1
  • 63
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell, C., Pachter, L., Salzberg, S.L., TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25 (2009), 1105–1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 66
    • 84939436660 scopus 로고    scopus 로고
    • Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains
    • Walker, D.G., Lue, L.F., Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains. Alzheimers Res. Ther., 7, 2015, 56.
    • (2015) Alzheimers Res. Ther. , vol.7 , pp. 56
    • Walker, D.G.1    Lue, L.F.2
  • 67
    • 0024729993 scopus 로고
    • In situ hybridization analysis for herpes simplex virus nucleic acids in Alzheimer disease
    • Walker, D.G., O'Kusky, J.R., McGeer, P.L., In situ hybridization analysis for herpes simplex virus nucleic acids in Alzheimer disease. Alzheimer Dis. Assoc. Disord. 3 (1989), 123–131.
    • (1989) Alzheimer Dis. Assoc. Disord. , vol.3 , pp. 123-131
    • Walker, D.G.1    O'Kusky, J.R.2    McGeer, P.L.3
  • 68
    • 84875655895 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease—a brief review of the basic science and clinical literature
    • Wyss-Coray, T., Rogers, J., Inflammation in Alzheimer disease—a brief review of the basic science and clinical literature. Cold Spring Harb. Perspect. Med., 2, 2012, a006346.
    • (2012) Cold Spring Harb. Perspect. Med. , vol.2 , pp. a006346
    • Wyss-Coray, T.1    Rogers, J.2
  • 70
    • 84959377661 scopus 로고    scopus 로고
    • Novel role of Src in priming Pyk2 phosphorylation
    • Zhao, M., Finlay, D., Zharkikh, I., Vuori, K., Novel role of Src in priming Pyk2 phosphorylation. PLoS One, 11, 2016, e0149231.
    • (2016) PLoS One , vol.11 , pp. e0149231
    • Zhao, M.1    Finlay, D.2    Zharkikh, I.3    Vuori, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.