-
1
-
-
68349154347
-
Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells
-
Allen JG, Lee MR, Han CY, Scherrer J, Flynn S, Boucher C, Zhao H, O'Connor AB, Roveto P, Bauer D, Graceffa R, Richards WG, Babij P,. 2009. Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells. Bioorg Med Chem Lett 19: 4924-4928.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 4924-4928
-
-
Allen, J.G.1
Lee, M.R.2
Han, C.Y.3
Scherrer, J.4
Flynn, S.5
Boucher, C.6
Zhao, H.7
O'Connor, A.B.8
Roveto, P.9
Bauer, D.10
Graceffa, R.11
Richards, W.G.12
Babij, P.13
-
2
-
-
0034002462
-
RAFTK/Pyk2-mediated cellular signalling
-
Avraham H, Park SY, Schinkmann K, Avraham S,. 2000. RAFTK/Pyk2-mediated cellular signalling. Cell Signal 12: 123-133.
-
(2000)
Cell Signal
, vol.12
, pp. 123-133
-
-
Avraham, H.1
Park, S.Y.2
Schinkmann, K.3
Avraham, S.4
-
3
-
-
0028826350
-
Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain
-
Avraham S, London R, Fu Y, Ota S, Hiregowdara D, Li J, Jiang S, Pasztor LM, White RA, Groopman JE,. 1995. Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem 270: 27742-27751.
-
(1995)
J Biol Chem
, vol.270
, pp. 27742-27751
-
-
Avraham, S.1
London, R.2
Fu, Y.3
Ota, S.4
Hiregowdara, D.5
Li, J.6
Jiang, S.7
Pasztor, L.M.8
White, R.A.9
Groopman, J.E.10
-
4
-
-
67650065066
-
Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts
-
Bruzzaniti A, Neff L, Sandoval A, Du L, Horne WC, Baron R,. 2009. Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts. Mol Cell Biol 29: 3644-3656.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3644-3656
-
-
Bruzzaniti, A.1
Neff, L.2
Sandoval, A.3
Du, L.4
Horne, W.C.5
Baron, R.6
-
5
-
-
34547453984
-
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis
-
Buckbinder L, Crawford DT, Qi H, Ke HZ, Olson LM, Long KR, Bonnette PC, Baumann AP, Hambor JE, Grasser WA, III, Pan LC, Owen TA, Luzzio MJ, Hulford CA, Gebhard DF, Paralkar VM, Simmons HA, Kath JC, Roberts WG, Smock SL, Guzman-Perez A, Brown TA, Li M,. 2007. Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis. Proc Natl Acad Sci USA 104 (25): 10619-10624.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.25
, pp. 10619-10624
-
-
Buckbinder, L.1
Crawford, D.T.2
Qi, H.3
Ke, H.Z.4
Olson, L.M.5
Long, K.R.6
Bonnette, P.C.7
Baumann, A.P.8
Hambor, J.E.9
Grasser, W.A.10
Pan, L.C.11
Owen, T.A.12
Luzzio, M.J.13
Hulford, C.A.14
Gebhard, D.F.15
Paralkar, V.M.16
Simmons, H.A.17
Kath, J.C.18
Roberts, W.G.19
Smock, S.L.20
Guzman-Perez, A.21
Brown, T.A.22
Li, M.23
more..
-
6
-
-
84878238896
-
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation
-
Cheng YH, Hooker RA, Nguyen K, Gerard-O'Riley R, Waning DL, Chitteti BR, Meijome TE, Chua HL, Plett AP, Orschell CM, Srour EF, Mayo LD, Pavalko FM, Bruzzaniti A, Kacena MA,. 2013. Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation. J Bone Miner Res 28: 1434-1445.
-
(2013)
J Bone Miner Res
, vol.28
, pp. 1434-1445
-
-
Cheng, Y.H.1
Hooker, R.A.2
Nguyen, K.3
Gerard-O'Riley, R.4
Waning, D.L.5
Chitteti, B.R.6
Meijome, T.E.7
Chua, H.L.8
Plett, A.P.9
Orschell, C.M.10
Srour, E.F.11
Mayo, L.D.12
Pavalko, F.M.13
Bruzzaniti, A.14
Kacena, M.A.15
-
7
-
-
84920933828
-
Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells
-
Cheng YH, Streicher DA, Waning DL, Chitteti BR, Gerard-O'Riley R, Horowitz MC, Bidwell JP, Pavalko FM, Srour EF, Mayo LD, Kacena MA,. 2015. Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells. J Cell Physiol 230: 578-586.
-
(2015)
J Cell Physiol
, vol.230
, pp. 578-586
-
-
Cheng, Y.H.1
Streicher, D.A.2
Waning, D.L.3
Chitteti, B.R.4
Gerard-O'Riley, R.5
Horowitz, M.C.6
Bidwell, J.P.7
Pavalko, F.M.8
Srour, E.F.9
Mayo, L.D.10
Kacena, M.A.11
-
8
-
-
77749309917
-
Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation
-
Ciovacco WA, Cheng YH, Horowitz MC, Kacena MA,. 2010. Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation. J Cell Biochem 109: 774-781.
-
(2010)
J Cell Biochem
, vol.109
, pp. 774-781
-
-
Ciovacco, W.A.1
Cheng, Y.H.2
Horowitz, M.C.3
Kacena, M.A.4
-
9
-
-
57449118281
-
The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation
-
Ciovacco WA, Goldberg CG, Taylor AF, Lemieux JM, Horowitz MC, Donahue HJ, Kacena MA,. 2009. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. Bone 44: 80-86.
-
(2009)
Bone
, vol.44
, pp. 80-86
-
-
Ciovacco, W.A.1
Goldberg, C.G.2
Taylor, A.F.3
Lemieux, J.M.4
Horowitz, M.C.5
Donahue, H.J.6
Kacena, M.A.7
-
10
-
-
84918823772
-
The reversal phase of the bone-remodeling cycle: Cellular prerequisites for coupling resorption and formation
-
Delaisse JM,. 2014. The reversal phase of the bone-remodeling cycle: Cellular prerequisites for coupling resorption and formation. Bonekey Rep 3: 561.
-
(2014)
Bonekey Rep
, vol.3
, pp. 561
-
-
Delaisse, J.M.1
-
11
-
-
0029907265
-
A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
-
Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J,. 1996. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383: 547-550.
-
(1996)
Nature
, vol.383
, pp. 547-550
-
-
Dikic, I.1
Tokiwa, G.2
Lev, S.3
Courtneidge, S.A.4
Schlessinger, J.5
-
12
-
-
0031028065
-
Thrombopoietin signal transduction in purified murine megakaryocytes
-
Drachman JG, Sabath DF, Fox NE, Kaushansky K,. 1997. Thrombopoietin signal transduction in purified murine megakaryocytes. Blood 89: 483-492.
-
(1997)
Blood
, vol.89
, pp. 483-492
-
-
Drachman, J.G.1
Sabath, D.F.2
Fox, N.E.3
Kaushansky, K.4
-
13
-
-
0034285013
-
The osteoblast: A sophisticated fibroblast under central surveillance
-
Ducy P, Schinke T, Karsenty G,. 2000. The osteoblast: A sophisticated fibroblast under central surveillance. Science 289: 1501-1504.
-
(2000)
Science
, vol.289
, pp. 1501-1504
-
-
Ducy, P.1
Schinke, T.2
Karsenty, G.3
-
14
-
-
0032168740
-
PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v) beta3 integrin, and phosphorylated by src kinase
-
Duong LT, Lakkakorpi PT, Nakamura I, Machwate M, Nagy RM, Rodan GA,. 1998. PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v) beta3 integrin, and phosphorylated by src kinase. J Clin Invest 102: 881-892.
-
(1998)
J Clin Invest
, vol.102
, pp. 881-892
-
-
Duong, L.T.1
Lakkakorpi, P.T.2
Nakamura, I.3
MacHwate, M.4
Nagy, R.M.5
Rodan, G.A.6
-
15
-
-
0035831497
-
Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2
-
Duong LT, Nakamura I, Lakkakorpi PT, Lipfert L, Bett AJ, Rodan GA,. 2001. Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2. J Biol Chem 276: 7484-7492.
-
(2001)
J Biol Chem
, vol.276
, pp. 7484-7492
-
-
Duong, L.T.1
Nakamura, I.2
Lakkakorpi, P.T.3
Lipfert, L.4
Bett, A.J.5
Rodan, G.A.6
-
16
-
-
0033743866
-
PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation
-
Duong LT, Rodan GA,. 2000. PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation. Cell Motil Cytoskeleton 47: 174-188.
-
(2000)
Cell Motil Cytoskeleton
, vol.47
, pp. 174-188
-
-
Duong, L.T.1
Rodan, G.A.2
-
17
-
-
84887836346
-
Focal adhesion kinases in adhesion structures and disease
-
Eleniste PP, Bruzzaniti A,. 2012. Focal adhesion kinases in adhesion structures and disease. J Signal Transduct 2012: 296450.
-
(2012)
J Signal Transduct
, vol.2012
, pp. 296450
-
-
Eleniste, P.P.1
Bruzzaniti, A.2
-
18
-
-
84859266874
-
Dynamin and PTP-PEST cooperatively regulate Pyk2 dephosphorylation in osteoclasts
-
Eleniste PP, Du L, Shivanna M, Bruzzaniti A,. 2012. Dynamin and PTP-PEST cooperatively regulate Pyk2 dephosphorylation in osteoclasts. Int J Biochem Cell Biol 44: 790-800.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 790-800
-
-
Eleniste, P.P.1
Du, L.2
Shivanna, M.3
Bruzzaniti, A.4
-
19
-
-
0037332596
-
C-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation
-
Faccio R, Takeshita S, Zallone A, Ross FP, Teitelbaum SL,. 2003. C-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation. J Clin Invest 111: 749-758.
-
(2003)
J Clin Invest
, vol.111
, pp. 749-758
-
-
Faccio, R.1
Takeshita, S.2
Zallone, A.3
Ross, F.P.4
Teitelbaum, S.L.5
-
20
-
-
84938149709
-
Biology of bone tissue: Structure, function, and factors that influence bone cells
-
Florencio-Silva R, Sasso GR, Sasso-Cerri E, Simoes MJ, Cerri PS,. 2015. Biology of bone tissue: Structure, function, and factors that influence bone cells. Biomed Res Int 2015: 421746.
-
(2015)
Biomed Res Int
, vol.2015
, pp. 421746
-
-
Florencio-Silva, R.1
Sasso, G.R.2
Sasso-Cerri, E.3
Simoes, M.J.4
Cerri, P.S.5
-
21
-
-
34548845081
-
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice
-
Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, Neff L, Sanjay A, Bruzzaniti A, De Camilli P, Baron R, Schlessinger J,. 2007. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol 178: 1053-1064.
-
(2007)
J Cell Biol
, vol.178
, pp. 1053-1064
-
-
Gil-Henn, H.1
Destaing, O.2
Sims, N.A.3
Aoki, K.4
Alles, N.5
Neff, L.6
Sanjay, A.7
Bruzzaniti, A.8
De Camilli, P.9
Baron, R.10
Schlessinger, J.11
-
22
-
-
65749105992
-
Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design
-
Han S, Mistry A, Chang JS, Cunningham D, Griffor M, Bonnette PC, Wang H, Chrunyk BA, Aspnes GE, Walker DP, Brosius AD, Buckbinder L,. 2009. Structural characterization of proline-rich tyrosine kinase 2 (PYK2) reveals a unique (DFG-out) conformation and enables inhibitor design. J Biol Chem 284: 13193-13201.
-
(2009)
J Biol Chem
, vol.284
, pp. 13193-13201
-
-
Han, S.1
Mistry, A.2
Chang, J.S.3
Cunningham, D.4
Griffor, M.5
Bonnette, P.C.6
Wang, H.7
Chrunyk, B.A.8
Aspnes, G.E.9
Walker, D.P.10
Brosius, A.D.11
Buckbinder, L.12
-
23
-
-
0028037648
-
Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts
-
Horowitz MC, Fields A, DeMeo D, Qian HY, Bothwell AL, Trepman E,. 1994. Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts. Endocrinology 135: 1032-1043.
-
(1994)
Endocrinology
, vol.135
, pp. 1032-1043
-
-
Horowitz, M.C.1
Fields, A.2
DeMeo, D.3
Qian, H.Y.4
Bothwell, A.L.5
Trepman, E.6
-
24
-
-
0019407729
-
Role of phosphodiesterase in the parathormone-stimulated adenosine 3',5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts
-
Jilka RL, Cohn DV,. 1981. Role of phosphodiesterase in the parathormone-stimulated adenosine 3',5'-monophosphate response in bone cell populations enriched in osteoclasts and osteoblasts. Endocrinology 109: 743-747.
-
(1981)
Endocrinology
, vol.109
, pp. 743-747
-
-
Jilka, R.L.1
Cohn, D.V.2
-
25
-
-
84875552076
-
The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties
-
Kacena MA, Gundberg CM, Kacena WJ III, Landis WJ, Boskey AL, Bouxsein ML, Horowitz MC,. 2013. The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties. J Cell Physiol 228: 1594-1600.
-
(2013)
J Cell Physiol
, vol.228
, pp. 1594-1600
-
-
Kacena, M.A.1
Gundberg, C.M.2
Kacena, W.J.3
Landis, W.J.4
Boskey, A.L.5
Bouxsein, M.L.6
Horowitz, M.C.7
-
26
-
-
84861211504
-
Megakaryocytes regulate expression of Pyk2 isoforms and caspase-mediated cleavage of actin in osteoblasts
-
Kacena MA, Eleniste PP, Cheng YH, Huang S, Shivanna M, Meijome TE, Mayo LD, Bruzzaniti A,. 2012. Megakaryocytes regulate expression of Pyk2 isoforms and caspase-mediated cleavage of actin in osteoblasts. J Biol Chem. 287: 17257-17268.
-
(2012)
J Biol Chem
, vol.287
, pp. 17257-17268
-
-
Kacena, M.A.1
Eleniste, P.P.2
Cheng, Y.H.3
Huang, S.4
Shivanna, M.5
Meijome, T.E.6
Mayo, L.D.7
Bruzzaniti, A.8
-
27
-
-
14144251106
-
Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype
-
Kacena MA, Gundberg CM, Nelson T, Horowitz MC,. 2005. Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotype. Bone 36: 215-223.
-
(2005)
Bone
, vol.36
, pp. 215-223
-
-
Kacena, M.A.1
Gundberg, C.M.2
Nelson, T.3
Horowitz, M.C.4
-
28
-
-
33749518042
-
Megakaryocyte-mediated inhibition of osteoclast development
-
Kacena MA, Nelson T, Clough ME, Lee SK, Lorenzo JA, Gundberg CM, Horowitz MC,. 2006. Megakaryocyte-mediated inhibition of osteoclast development. Bone 39: 991-999.
-
(2006)
Bone
, vol.39
, pp. 991-999
-
-
Kacena, M.A.1
Nelson, T.2
Clough, M.E.3
Lee, S.K.4
Lorenzo, J.A.5
Gundberg, C.M.6
Horowitz, M.C.7
-
29
-
-
3142669441
-
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF- E2
-
Kacena MA, Shivdasani RA, Wilson K, Xi Y, Troiano N, Nazarian A, Gundberg CM, Bouxsein ML, Lorenzo JA, Horowitz MC,. 2004. Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF- E2. J Bone Miner Res 19: 652-660.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 652-660
-
-
Kacena, M.A.1
Shivdasani, R.A.2
Wilson, K.3
Xi, Y.4
Troiano, N.5
Nazarian, A.6
Gundberg, C.M.7
Bouxsein, M.L.8
Lorenzo, J.A.9
Horowitz, M.C.10
-
30
-
-
0035094445
-
Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes
-
Kintscher U, Wakino S, Kim S, Fleck E, Hsueh WA, Law RE,. 2001. Angiotensin II induces migration and Pyk2/paxillin phosphorylation of human monocytes. Hypertension 37: 587-593.
-
(2001)
Hypertension
, vol.37
, pp. 587-593
-
-
Kintscher, U.1
Wakino, S.2
Kim, S.3
Fleck, E.4
Hsueh, W.A.5
Law, R.E.6
-
31
-
-
0037838889
-
PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption
-
Lakkakorpi PT, Bett AJ, Lipfert L, Rodan GA, Duong lT,. 2003. PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption. Journal of Biological Chemistry 278: 11502-11512.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 11502-11512
-
-
Lakkakorpi, P.T.1
Bett, A.J.2
Lipfert, L.3
Rodan, G.A.4
Duong, L.5
-
32
-
-
77950385868
-
Involvement of integrins alpha(3)beta(1) and alpha(5)beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation
-
Lemieux JM, Horowitz MC, Kacena MA,. 2010. Involvement of integrins alpha(3)beta(1) and alpha(5)beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation. J Cell Biochem 109: 927-932.
-
(2010)
J Cell Biochem
, vol.109
, pp. 927-932
-
-
Lemieux, J.M.1
Horowitz, M.C.2
Kacena, M.A.3
-
33
-
-
84919740811
-
GATA-1 deficiency rescues trabecular but not cortical bone in OPG deficient mice
-
Meijome TE, Hooker RA, Cheng Y-H, Walter W, Horowitz MC, Fuchs RK, Kacena MA,. 2015. GATA-1 deficiency rescues trabecular but not cortical bone in OPG deficient mice. J Cell Physiol 230: 783-790.
-
(2015)
J Cell Physiol
, vol.230
, pp. 783-790
-
-
Meijome, T.E.1
Hooker, R.A.2
Cheng, Y.-H.3
Walter, W.4
Horowitz, M.C.5
Fuchs, R.K.6
Kacena, M.A.7
-
34
-
-
3142615409
-
The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation
-
Meyer AN, Gastwirt RF, Schlaepfer DD, Donoghue DJ,. 2004. The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation. J Biol Chem 279: 28450-28457.
-
(2004)
J Biol Chem
, vol.279
, pp. 28450-28457
-
-
Meyer, A.N.1
Gastwirt, R.F.2
Schlaepfer, D.D.3
Donoghue, D.J.4
-
35
-
-
2342442847
-
Src kinase activity is essential for osteoclast function
-
Miyazaki T, Sanjay A, Neff L, Tanaka S, Horne WC, Baron R,. 2004. Src kinase activity is essential for osteoclast function. J Biol Chem 279: 17660-17666.
-
(2004)
J Biol Chem
, vol.279
, pp. 17660-17666
-
-
Miyazaki, T.1
Sanjay, A.2
Neff, L.3
Tanaka, S.4
Horne, W.C.5
Baron, R.6
-
36
-
-
0034656081
-
Involvement of proline-rich tyrosine kinase 2 in platelet activation: Tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2
-
Ohmori T, Yatomi Y, Asazuma N, Satoh K, Ozaki Y,. 2000. Involvement of proline-rich tyrosine kinase 2 in platelet activation: Tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2. Biochem J 347: 561-569.
-
(2000)
Biochem J
, vol.347
, pp. 561-569
-
-
Ohmori, T.1
Yatomi, Y.2
Asazuma, N.3
Satoh, K.4
Ozaki, Y.5
-
37
-
-
4043054389
-
RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner
-
Park SY, Avraham HK, Avraham S,. 2004. RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. J Biol Chem 279: 33315-33322.
-
(2004)
J Biol Chem
, vol.279
, pp. 33315-33322
-
-
Park, S.Y.1
Avraham, H.K.2
Avraham, S.3
-
38
-
-
0034865951
-
Podosomes in osteoclast-like cells: Structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin alphaVbeta3
-
Pfaff M, Jurdic P,. 2001. Podosomes in osteoclast-like cells: Structural analysis and cooperative roles of paxillin, proline-rich tyrosine kinase 2 (Pyk2) and integrin alphaVbeta3. J Cell Sci 114: 2775-2786.
-
(2001)
J Cell Sci
, vol.114
, pp. 2775-2786
-
-
Pfaff, M.1
Jurdic, P.2
-
39
-
-
0035825121
-
Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v) beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility
-
Sanjay A, Houghton A, Neff L, DiDomenico E, Bardelay C, Antoine E, Levy J, Gailit J, Bowtell D, Horne WC, Baron R,. 2001. Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v) beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility. J Cell Biol 152: 181-195.
-
(2001)
J Cell Biol
, vol.152
, pp. 181-195
-
-
Sanjay, A.1
Houghton, A.2
Neff, L.3
DiDomenico, E.4
Bardelay, C.5
Antoine, E.6
Levy, J.7
Gailit, J.8
Bowtell, D.9
Horne, W.C.10
Baron, R.11
-
40
-
-
0020328961
-
Formation of bone by isolated, cultured osteoblasts in millipore diffusion chambers
-
Simmons DJ, Kent GN, Jilka RL, Scott DM, Fallon M, Cohn DV,. 1982. Formation of bone by isolated, cultured osteoblasts in millipore diffusion chambers. Calcif Tissue Int 34: 291-294.
-
(1982)
Calcif Tissue Int
, vol.34
, pp. 291-294
-
-
Simmons, D.J.1
Kent, G.N.2
Jilka, R.L.3
Scott, D.M.4
Fallon, M.5
Cohn, D.V.6
-
41
-
-
0028919516
-
Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP)
-
Stanford CM, Jacobson PA, Eanes ED, Lembke LA, Midura RJ,. 1995. Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP). J Biol Chem 270: 9420-9428.
-
(1995)
J Biol Chem
, vol.270
, pp. 9420-9428
-
-
Stanford, C.M.1
Jacobson, P.A.2
Eanes, E.D.3
Lembke, L.A.4
Midura, R.J.5
-
42
-
-
84860572471
-
Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells
-
Tse KW, Lin KB, Dang-Lawson M, Guzman-Perez A, Aspnes GE, Buckbinder L, Gold MR,. 2012. Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells. Cell Immunol 275: 47-54.
-
(2012)
Cell Immunol
, vol.275
, pp. 47-54
-
-
Tse, K.W.1
Lin, K.B.2
Dang-Lawson, M.3
Guzman-Perez, A.4
Aspnes, G.E.5
Buckbinder, L.6
Gold, M.R.7
-
43
-
-
0030718597
-
High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice
-
Villeval JL, Cohen-Solal K, Tulliez M, Giraudier S, Guichard J, Burstein SA, Cramer EM, Vainchenker W, Wendling F,. 1997. High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice. Blood 90: 4369-4383.
-
(1997)
Blood
, vol.90
, pp. 4369-4383
-
-
Villeval, J.L.1
Cohen-Solal, K.2
Tulliez, M.3
Giraudier, S.4
Guichard, J.5
Burstein, S.A.6
Cramer, E.M.7
Vainchenker, W.8
Wendling, F.9
-
44
-
-
65749102118
-
Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity
-
Walker DP, Zawistoski MP, McGlynn MA, Li JC, Kung DW, Bonnette PC, Baumann A, Buckbinder L, Houser JA, Boer J, Mistry A, Han S, Xing L, Guzman-Perez A,. 2009. Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg Med Chem Lett 19: 3253-3258.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 3253-3258
-
-
Walker, D.P.1
Zawistoski, M.P.2
McGlynn, M.A.3
Li, J.C.4
Kung, D.W.5
Bonnette, P.C.6
Baumann, A.7
Buckbinder, L.8
Houser, J.A.9
Boer, J.10
Mistry, A.11
Han, S.12
Xing, L.13
Guzman-Perez, A.14
-
45
-
-
0037450657
-
Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin
-
Wang Q, Xie Y, Du QS, Wu X, Feng X, Mei L, McDonald JM, Xiong W,. 2003. Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin. J Cell Biol 160: 565-575.
-
(2003)
J Cell Biol
, vol.160
, pp. 565-575
-
-
Wang, Q.1
Xie, Y.2
Du, Q.S.3
Wu, X.4
Feng, X.5
Mei, L.6
McDonald, J.M.7
Xiong, W.8
-
46
-
-
0016820226
-
Target cells in bone for parathormone and calcitonin are different: Enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces
-
Wong GL, Cohn DV,. 1975. Target cells in bone for parathormone and calcitonin are different: Enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces. Proc Natl Acad Sci USA 72: 3167-3171.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 3167-3171
-
-
Wong, G.L.1
Cohn, D.V.2
-
47
-
-
0036756379
-
Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts
-
Zhang Z, Neff L, Bothwell AL, Baron R, Horne WC,. 2002. Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts. Bone 31: 359-365.
-
(2002)
Bone
, vol.31
, pp. 359-365
-
-
Zhang, Z.1
Neff, L.2
Bothwell, A.L.3
Baron, R.4
Horne, W.C.5
|