메뉴 건너뛰기




Volumn 11, Issue 2, 2016, Pages

Novel role of Src in priming Pyk2 phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; FOCAL ADHESION KINASE 2; INTEGRIN; PROTEIN TYROSINE KINASE; FOCAL ADHESION KINASE; FYN PROTEIN, HUMAN; FYN PROTEIN, MOUSE; PROTEIN BINDING; PROTEIN KINASE FYN; PROTEIN KINASE YES; PTK2B PROTEIN, MOUSE; YES1 PROTEIN, HUMAN; YES1 PROTEIN, MOUSE;

EID: 84959377661     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0149231     Document Type: Article
Times cited : (44)

References (39)
  • 2
    • 82755194790 scopus 로고    scopus 로고
    • Focal adhesion kinase and tumour angiogenesis
    • 21984450
    • Lechertier T, Hodivala-Dilke K (2012) Focal adhesion kinase and tumour angiogenesis. The Journal of Pathology 226: 404-412. doi: 10.1002/path.3018 PMID: 21984450
    • (2012) The Journal of Pathology , vol.226 , pp. 404-412
    • Lechertier, T.1    Hodivala-Dilke, K.2
  • 3
    • 0029154733 scopus 로고
    • Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions
    • 7544443
    • Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, et al. (1995) Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions. Nature 376: 737-745. PMID: 7544443
    • (1995) Nature , vol.376 , pp. 737-745
    • Lev, S.1    Moreno, H.2    Martinez, R.3    Canoll, P.4    Peles, E.5    Musacchio, J.M.6
  • 4
    • 0029096541 scopus 로고
    • Cloning and characterization of cell adhesion kinase β, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily
    • 7673154
    • Sasaki H, Nagura K, Ishino M, Tobioka H, Kotani K, Sasaki T (1995) Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily. Journal of Biological Chemistry 270: 21206-21219. PMID: 7673154
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 21206-21219
    • Sasaki, H.1    Nagura, K.2    Ishino, M.3    Tobioka, H.4    Kotani, K.5    Sasaki, T.6
  • 5
    • 0028826350 scopus 로고
    • Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain
    • 7499242
    • Avraham S, London R, Fu Y, Ota S, Hiregowdara D, Li J, et al. (1995) Identification and Characterization of a Novel Related Adhesion Focal Tyrosine Kinase (RAFTK) from Megakaryocytes and Brain. Journal of Biological Chemistry 270: 27742-27751. PMID: 7499242
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 27742-27751
    • Avraham, S.1    London, R.2    Fu, Y.3    Ota, S.4    Hiregowdara, D.5    Li, J.6
  • 6
    • 0034232062 scopus 로고    scopus 로고
    • Absence of marginal zone B cells in pyk-2-deficient mice defines their role in the humoral response
    • 10881171
    • Guinamard R, Okigaki M, Schlessinger J, Ravetch JV (2000) Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat Immunol 1: 31-36. PMID: 10881171
    • (2000) Nat Immunol , vol.1 , pp. 31-36
    • Guinamard, R.1    Okigaki, M.2    Schlessinger, J.3    Ravetch, J.V.4
  • 8
    • 13444294190 scopus 로고    scopus 로고
    • Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets
    • 15720813
    • Hoelzinger DB, Mariani L, Weis J, Woyke T, Berens TJ, McDonough WS, et al. (2005) Gene Expression Profile of Glioblastoma Multiforme Invasive Phenotype Points to New Therapeutic Targets. Neoplasia 7: 7-16. PMID: 15720813
    • (2005) Neoplasia , vol.7 , pp. 7-16
    • Hoelzinger, D.B.1    Mariani, L.2    Weis, J.3    Woyke, T.4    Berens, T.J.5    McDonough, W.S.6
  • 9
    • 42049113411 scopus 로고    scopus 로고
    • Compensatory role for pyk2 during angiogenesis in adult mice lacking endothelial cell FAK
    • 18391070
    • Weis SM, Lim S-T, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, et al. (2008) Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. The Journal of Cell Biology 181: 43-50. doi: 10.1083/jcb.200710038 PMID: 18391070
    • (2008) The Journal of Cell Biology , vol.181 , pp. 43-50
    • Weis, S.M.1    Lim, S.-T.2    Lutu-Fuga, K.M.3    Barnes, L.A.4    Chen, X.L.5    Göthert, J.R.6
  • 10
    • 79956306365 scopus 로고    scopus 로고
    • Compensatory function of pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity
    • 21471206
    • Fan H, Guan J-L (2011) Compensatory Function of Pyk2 Protein in the Promotion of Focal Adhesion Kinase (FAK)-null Mammary Cancer Stem Cell Tumorigenicity and Metastatic Activity. Journal of Biological Chemistry 286: 18573-18582. doi: 10.1074/jbc.M110.200717 PMID: 21471206
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 18573-18582
    • Fan, H.1    Guan, J.-L.2
  • 11
    • 81055127013 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment
    • 21903606
    • Stokes JB, Adair SJ, Slack-Davis JK, Walters DM, Tilghman RW, Hershey ED, et al. (2011) Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment. Molecular Cancer Therapeutics 10: 2135-2145. doi: 10.1158/1535-7163.MCT-11-0261 PMID: 21903606
    • (2011) Molecular Cancer Therapeutics , vol.10 , pp. 2135-2145
    • Stokes, J.B.1    Adair, S.J.2    Slack-Davis, J.K.3    Walters, D.M.4    Tilghman, R.W.5    Hershey, E.D.6
  • 12
    • 84895519775 scopus 로고    scopus 로고
    • Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines
    • 24523919
    • Yoon H, Choi Y-L, Song J-Y, Do I, Kang SY, Ko Y-H, et al. (2014) Targeted Inhibition of FAK, PYK2 and BCL-XL Synergistically Enhances Apoptosis in Ovarian Clear Cell Carcinoma Cell Lines. PLoS ONE 9: e88587. doi: 10.1371/journal.pone.0088587 PMID: 24523919
    • (2014) PLoS One , vol.9 , pp. e88587
    • Yoon, H.1    Choi, Y.-L.2    Song, J.-Y.3    Do, I.4    Kang, S.Y.5    Ko, Y.-H.6
  • 13
    • 0242495710 scopus 로고    scopus 로고
    • Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction
    • 14585964
    • Cooper LA, Shen T-L, Guan J-L (2003) Regulation of Focal Adhesion Kinase by Its Amino-Terminal Domain through an Autoinhibitory Interaction. Molecular and Cellular Biology 23: 8030-8041. PMID: 14585964
    • (2003) Molecular and Cellular Biology , vol.23 , pp. 8030-8041
    • Cooper, L.A.1    Shen, T.-L.2    Guan, J.-L.3
  • 17
    • 0028877919 scopus 로고
    • Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for src family kinases
    • 7529876
    • Calalb MB, Polte TR, Hanks SK (1995) Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Molecular and Cellular Biology 15: 954-963. PMID: 7529876
    • (1995) Molecular and Cellular Biology , vol.15 , pp. 954-963
    • Calalb, M.B.1    Polte, T.R.2    Hanks, S.K.3
  • 18
    • 0033002997 scopus 로고    scopus 로고
    • Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of pyk2
    • 10373530
    • Owen JD, Ruest PJ, Fry DW, Hanks SK (1999) Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2. Molecular and Cellular Biology 19: 4806-4818. PMID: 10373530
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 4806-4818
    • Owen, J.D.1    Ruest, P.J.2    Fry, D.W.3    Hanks, S.K.4
  • 19
    • 34250026140 scopus 로고    scopus 로고
    • Structural basis for the autoinhibition of focal adhesion kinase
    • 17574028
    • Lietha D, Cai X, Ceccarelli DFJ, Li Y, Schaller MD, Eck MJ (2007) Structural Basis for the Autoinhibition of Focal Adhesion Kinase. Cell 129: 1177-1187. PMID: 17574028
    • (2007) Cell , vol.129 , pp. 1177-1187
    • Lietha, D.1    Cai, X.2    Ceccarelli, D.F.J.3    Li, Y.4    Schaller, M.D.5    Eck, M.J.6
  • 21
    • 4043054389 scopus 로고    scopus 로고
    • RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a src-independent manner
    • 15166227
    • Park S-Y, Avraham HK, Avraham S (2004) RAFTK/Pyk2 Activation Is Mediated by Trans-acting Autophosphorylation in a Src-independent Manner. Journal of Biological Chemistry 279: 33315-33322. PMID: 15166227
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 33315-33322
    • Park, S.-Y.1    Avraham, H.K.2    Avraham, S.3
  • 22
    • 77957802351 scopus 로고    scopus 로고
    • The pyk2 FERM regulates pyk2 complex formation and phosphorylation
    • 20849950
    • Riggs D, Yang Z, Kloss J, Loftus JC (2011) The Pyk2 FERM regulates Pyk2 complex formation and phosphorylation. Cellular Signalling 23: 288-296. doi: 10.1016/j.cellsig.2010.09.015 PMID: 20849950
    • (2011) Cellular Signalling , vol.23 , pp. 288-296
    • Riggs, D.1    Yang, Z.2    Kloss, J.3    Loftus, J.C.4
  • 23
    • 41149130736 scopus 로고    scopus 로고
    • Protein-tyrosine kinase CAKβ/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 α2 helix and thus forming its dimer
    • 18031286
    • Kohno T, Matsuda E, Sasaki H, Sasaki T (2008) Protein-tyrosine kinase CAKβ/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 α2 helix and thus forming its dimer. Biochem J 410: 513-523. PMID: 18031286
    • (2008) Biochem J , vol.410 , pp. 513-523
    • Kohno, T.1    Matsuda, E.2    Sasaki, H.3    Sasaki, T.4
  • 24
    • 1842836011 scopus 로고    scopus 로고
    • Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells
    • 12748308
    • Laird AD, Li G, Moss KG, Blake RA, Broome MA, Cherrington JM, et al. (2003) Src Family Kinase Activity Is Required for Signal Tranducer and Activator of Transcription 3 and Focal Adhesion Kinase Phosphorylation and Vascular Endothelial Growth Factor Signaling in Vivo and for Anchorage-dependent and -independent Growth of Human Tumor Cells. Molecular Cancer Therapeutics 2: 461-469. PMID: 12748308
    • (2003) Molecular Cancer Therapeutics , vol.2 , pp. 461-469
    • Laird, A.D.1    Li, G.2    Moss, K.G.3    Blake, R.A.4    Broome, M.A.5    Cherrington, J.M.6
  • 25
    • 0033522510 scopus 로고    scopus 로고
    • Src family kinases are required for integrin but not PDGFR signal transduction
    • 10228160
    • Klinghoffer RA, Sachsenmaier C, Cooper JA, Soriano P (1999) Src family kinases are required for integrin but not PDGFR signal transduction. The EMBO Journal 18: 2459-2471. PMID: 10228160
    • (1999) The EMBO Journal , vol.18 , pp. 2459-2471
    • Klinghoffer, R.A.1    Sachsenmaier, C.2    Cooper, J.A.3    Soriano, P.4
  • 26
    • 0031915021 scopus 로고    scopus 로고
    • Integrin signalling and tyrosine phosphorylation: Just the FAKs?
    • 9695829
    • Schlaepfer DD, Hunter T (1998) Integrin signalling and tyrosine phosphorylation: just the FAKs? Trends in Cell Biology 8: 151-157. PMID: 9695829
    • (1998) Trends in Cell Biology , vol.8 , pp. 151-157
    • Schlaepfer, D.D.1    Hunter, T.2
  • 27
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: The first ten years
    • 12640026
    • Parsons JT (2003) Focal adhesion kinase: the first ten years. Journal of Cell Science 116: 1409-1416. PMID: 12640026
    • (2003) Journal of Cell Science , vol.116 , pp. 1409-1416
    • Parsons, J.T.1
  • 28
    • 67651085772 scopus 로고    scopus 로고
    • Signal transduction by focal adhesion kinase in cancer
    • 19169797
    • Zhao J, Guan J-L (2009) Signal transduction by focal adhesion kinase in cancer. Cancer and Metastasis Reviews 28: 35-49. doi: 10.1007/s10555-008-9165-4 PMID: 19169797
    • (2009) Cancer and Metastasis Reviews , vol.28 , pp. 35-49
    • Zhao, J.1    Guan, J.-L.2
  • 29
    • 0027507115 scopus 로고
    • Signalling through SH2 and SH3 domains
    • 14731533
    • Mayer BJ, Baltimore D (1993) Signalling through SH2 and SH3 domains. Trends in Cell Biology 3: 8-13. PMID: 14731533
    • (1993) Trends in Cell Biology , vol.3 , pp. 8-13
    • Mayer, B.J.1    Baltimore, D.2
  • 32
    • 0027436135 scopus 로고
    • Binding of the src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides
    • 7504171
    • Bibbins KB, Boeuf H, Varmus HE (1993) Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides. Molecular and Cellular Biology 13: 7278-7287. PMID: 7504171
    • (1993) Molecular and Cellular Biology , vol.13 , pp. 7278-7287
    • Bibbins, K.B.1    Boeuf, H.2    Varmus, H.E.3
  • 33
    • 0025211917 scopus 로고
    • Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src
    • 2108315
    • Hirai H, Varmus HE (1990) Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src. Molecular and Cellular Biology 10: 1307-1318. PMID: 2108315
    • (1990) Molecular and Cellular Biology , vol.10 , pp. 1307-1318
    • Hirai, H.1    Varmus, H.E.2
  • 34
    • 17644397421 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of β3 integrin provides a binding site for pyk2
    • 15695828
    • Butler B, Blystone SD (2005) Tyrosine Phosphorylation of β3 Integrin Provides a Binding Site for Pyk2. Journal of Biological Chemistry 280: 14556-14562. PMID: 15695828
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 14556-14562
    • Butler, B.1    Blystone, S.D.2
  • 35
    • 0029907265 scopus 로고    scopus 로고
    • A role for pyk2 and src in linking gprotein-coupled receptors with MAP kinase activation
    • 8849729
    • Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J (1996) A role for Pyk2 and Src in linking Gprotein-coupled receptors with MAP kinase activation. Nature 383: 547-550. PMID: 8849729
    • (1996) Nature , vol.383 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 36
    • 84906935511 scopus 로고    scopus 로고
    • FAK in cancer: Mechanistic findings and clinical applications
    • 25098269
    • Sulzmaier FJ, Jean C, Schlaepfer DD (2014) FAK in cancer: mechanistic findings and clinical applications. Nat Rev Cancer 14: 598-610. doi: 10.1038/nrc3792 PMID: 25098269
    • (2014) Nat Rev Cancer , vol.14 , pp. 598-610
    • Sulzmaier, F.J.1    Jean, C.2    Schlaepfer, D.D.3
  • 38
    • 84937054160 scopus 로고    scopus 로고
    • The focal adhesion kinase pyk2 links Ca2+ signalling to src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
    • 25967238
    • Canobbio I, Cipolla L, Guidetti Gianni F, Manganaro D, Visconte C, Kim S, et al. (2015) The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. Biochemical Journal 469: 199-210. doi: 10.1042/BJ20150048 PMID: 25967238
    • (2015) Biochemical Journal , vol.469 , pp. 199-210
    • Canobbio, I.1    Cipolla, L.2    Guidetti Gianni, F.3    Manganaro, D.4    Visconte, C.5    Kim, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.