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Volumn 90, Issue 19, 2016, Pages 8563-8574

Complementary effects of interleukin-15 and alpha interferon induce immunity in hepatitis B virus transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; INTERLEUKIN 15; DRUG CARRIER; HEPATITIS B ANTIBODY;

EID: 84990189194     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01030-16     Document Type: Article
Times cited : (16)

References (47)
  • 1
    • 84919848147 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Trepo C, Chan HL, Lok A. 2014. Hepatitis B virus infection. Lancet 384:2053-2063. http://dx.doi.org/10.1016/S0140-6736(14)60220-8
    • (2014) Lancet , vol.384 , pp. 2053-2063
    • Trepo, C.1    Chan, H.L.2    Lok, A.3
  • 2
    • 33645729182 scopus 로고    scopus 로고
    • Immunobiology and pathogenesis of viral hepatitis
    • Guidotti LG, Chisari FV. 2006. Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 1:23-61. http://dx.doi.org/10.1146/annurev.pathol.1.110304.100230
    • (2006) Annu Rev Pathol , vol.1 , pp. 23-61
    • Guidotti, L.G.1    Chisari, F.V.2
  • 3
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. 2005. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5:215-229. http://dx.doi.org/10.1038/nri1573
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 5
    • 33847406557 scopus 로고    scopus 로고
    • PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver
    • Maier H, Isogawa M, Freeman GJ, Chisari FV. 2007. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. J Immunol 178:2714-2720. http://dx.doi.org/10.4049/jimmunol.178.5.2714
    • (2007) J Immunol , vol.178 , pp. 2714-2720
    • Maier, H.1    Isogawa, M.2    Freeman, G.J.3    Chisari, F.V.4
  • 6
    • 84877014011 scopus 로고    scopus 로고
    • PegIFN-α2a for the treatment of chronic hepatitis B and C: a 10-year history
    • Degasperi E, Vigano M, Aghemo A, Lampertico P, Colombo M. 2013. PegIFN-α2a for the treatment of chronic hepatitis B and C: a 10-year history. Expert Rev Anti Infect Ther 11:459-474. http://dx.doi.org/10.1586/eri.13.37
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 459-474
    • Degasperi, E.1    Vigano, M.2    Aghemo, A.3    Lampertico, P.4    Colombo, M.5
  • 13
    • 0037093844 scopus 로고    scopus 로고
    • Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells
    • Schluns KS, Williams K, Ma A, Zheng XX, Lefrancois L. 2002. Requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 168:4827-4831. http://dx.doi.org/10.4049/jimmunol.168.10.4827
    • (2002) J Immunol , vol.168 , pp. 4827-4831
    • Schluns, K.S.1    Williams, K.2    Ma, A.3    Zheng, X.X.4    Lefrancois, L.5
  • 14
    • 84899464260 scopus 로고    scopus 로고
    • The unconventional expression of IL-15 and its role in NK cell homeostasis
    • Huntington ND. 2014. The unconventional expression of IL-15 and its role in NK cell homeostasis. Immunol Cell Biol 92:210-213. http://dx.doi.org/10.1038/icb.2014.1
    • (2014) Immunol Cell Biol , vol.92 , pp. 210-213
    • Huntington, N.D.1
  • 15
    • 84866654260 scopus 로고    scopus 로고
    • IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 high CD4+ T cells
    • Van Belle TL, Dooms H, Boonefaes T, Wei XQ, Leclercq G, Grooten J. 2012. IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 high CD4+ T cells. PLoS One 7:e45299. http://dx.doi.org/10.1371/journal.pone.0045299
    • (2012) PLoS One , vol.7
    • Van Belle, T.L.1    Dooms, H.2    Boonefaes, T.3    Wei, X.Q.4    Leclercq, G.5    Grooten, J.6
  • 19
    • 84865163394 scopus 로고    scopus 로고
    • Interleukin-15 suppresses hepatitis B virus replication via IFN-γ production in a C57BL/6 mouse model
    • Yin W, Xu L, Sun R, Wei H, Tian Z. 2012. Interleukin-15 suppresses hepatitis B virus replication via IFN-γ production in a C57BL/6 mouse model. Liver Int 32:1306-1314. http://dx.doi.org/10.1111/j.1478-3231.2012.02773.x
    • (2012) Liver Int , vol.32 , pp. 1306-1314
    • Yin, W.1    Xu, L.2    Sun, R.3    Wei, H.4    Tian, Z.5
  • 20
    • 0029130068 scopus 로고
    • High-level hepatitis B virus replication in transgenic mice
    • Guidotti LG, Matzke B, Schaller H, Chisari FV. 1995. High-level hepatitis B virus replication in transgenic mice. J Virol 69:6158-6169
    • (1995) J Virol , vol.69 , pp. 6158-6169
    • Guidotti, L.G.1    Matzke, B.2    Schaller, H.3    Chisari, F.V.4
  • 21
    • 84936776606 scopus 로고    scopus 로고
    • Mouse models of hepatitis B virus infection comprising host-virus immunologic interactions
    • Inuzuka T, Takahashi K, Chiba T, Marusawa H. 2014. Mouse models of hepatitis B virus infection comprising host-virus immunologic interactions. Pathogens 3:377-389. http://dx.doi.org/10.3390/pathogens3020377
    • (2014) Pathogens , vol.3 , pp. 377-389
    • Inuzuka, T.1    Takahashi, K.2    Chiba, T.3    Marusawa, H.4
  • 22
    • 0032211129 scopus 로고    scopus 로고
    • Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice
    • Shimizu Y, Guidotti LG, Fowler P, Chisari FV. 1998. Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice. J Immunol 161:4520-4529
    • (1998) J Immunol , vol.161 , pp. 4520-4529
    • Shimizu, Y.1    Guidotti, L.G.2    Fowler, P.3    Chisari, F.V.4
  • 23
    • 84873088935 scopus 로고    scopus 로고
    • A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice
    • Buchmann P, Dembek C, Kuklick L, Jager C, Tedjokusumo R, von Freyend MJ, Drebber U, Janowicz Z, Melber K, Protzer U. 2013. A novel therapeutic hepatitis B vaccine induces cellular and humoral immune responses and breaks tolerance in hepatitis B virus (HBV) transgenic mice. Vaccine 31:1197-1203. http://dx.doi.org/10.1016/j.vaccine.2012.12.074
    • (2013) Vaccine , vol.31 , pp. 1197-1203
    • Buchmann, P.1    Dembek, C.2    Kuklick, L.3    Jager, C.4    Tedjokusumo, R.5    von Freyend, M.J.6    Drebber, U.7    Janowicz, Z.8    Melber, K.9    Protzer, U.10
  • 25
    • 84879760446 scopus 로고    scopus 로고
    • IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression
    • Gil-Farina I, Di Scala M, Vanrell L, Olague C, Vales A, High KA, Prieto J, Mingozzi F, Gonzalez-Aseguinolaza G. 2013. IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression. PLoS One 8:e67748. http://dx.doi.org/10.1371/journal.pone.0067748
    • (2013) PLoS One , vol.8
    • Gil-Farina, I.1    Di Scala, M.2    Vanrell, L.3    Olague, C.4    Vales, A.5    High, K.A.6    Prieto, J.7    Mingozzi, F.8    Gonzalez-Aseguinolaza, G.9
  • 27
    • 84944449107 scopus 로고    scopus 로고
    • Natural killer cells in viral hepatitis
    • Rehermann B. 2015. Natural killer cells in viral hepatitis. Cell Mol Gastroenterol Hepatol 1:578-588. http://dx.doi.org/10.1016/j.jcmgh.2015.09.004
    • (2015) Cell Mol Gastroenterol Hepatol , vol.1 , pp. 578-588
    • Rehermann, B.1
  • 29
    • 58149191881 scopus 로고    scopus 로고
    • The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
    • Kinter AL, Godbout EJ, McNally JP, Sereti I, Roby GA, O'Shea MA, Fauci AS. 2008. The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J Immunol 181:6738-6746. http://dx.doi.org/10.4049/jimmunol.181.10.6738
    • (2008) J Immunol , vol.181 , pp. 6738-6746
    • Kinter, A.L.1    Godbout, E.J.2    McNally, J.P.3    Sereti, I.4    Roby, G.A.5    O'Shea, M.A.6    Fauci, A.S.7
  • 30
    • 79952767536 scopus 로고    scopus 로고
    • IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity
    • Terawaki S, Chikuma S, Shibayama S, Hayashi T, Yoshida T, Okazaki T, Honjo T. 2011. IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. J Immunol 186:2772-2779. http://dx.doi.org/10.4049/jimmunol.1003208
    • (2011) J Immunol , vol.186 , pp. 2772-2779
    • Terawaki, S.1    Chikuma, S.2    Shibayama, S.3    Hayashi, T.4    Yoshida, T.5    Okazaki, T.6    Honjo, T.7
  • 32
    • 77953747963 scopus 로고    scopus 로고
    • The PD-1 pathway in tolerance and autoimmunity
    • Francisco LM, Sage PT, Sharpe AH. 2010. The PD-1 pathway in tolerance and autoimmunity. Immunol Rev 236:219-242. http://dx.doi.org/10.1111/j.1600-065X.2010.00923.x
    • (2010) Immunol Rev , vol.236 , pp. 219-242
    • Francisco, L.M.1    Sage, P.T.2    Sharpe, A.H.3
  • 33
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir ME, Butte MJ, Freeman GJ, Sharpe AH. 2008. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 26:677-704. http://dx.doi.org/10.1146/annurev.immunol.26.021607.090331
    • (2008) Annu Rev Immunol , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3    Sharpe, A.H.4
  • 34
    • 84937837169 scopus 로고    scopus 로고
    • Molecular and cellular insights into T cell exhaustion
    • Wherry EJ, Kurachi M. 2015. Molecular and cellular insights into T cell exhaustion. Nat Rev Immunol 15:486-499. http://dx.doi.org/10.1038/nri3862
    • (2015) Nat Rev Immunol , vol.15 , pp. 486-499
    • Wherry, E.J.1    Kurachi, M.2
  • 35
    • 49049107410 scopus 로고    scopus 로고
    • IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host-like disease
    • Miyagawa F, Tagaya Y, Kim BS, Patel HJ, Ishida K, Ohteki T, Waldmann TA, Katz SI. 2008. IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host-like disease. J Immunol 181:1109-1119. http://dx.doi.org/10.4049/jimmunol.181.2.1109
    • (2008) J Immunol , vol.181 , pp. 1109-1119
    • Miyagawa, F.1    Tagaya, Y.2    Kim, B.S.3    Patel, H.J.4    Ishida, K.5    Ohteki, T.6    Waldmann, T.A.7    Katz, S.I.8
  • 38
    • 0021931028 scopus 로고
    • High levels of cytoplasmic hepatitis B core antigen as reliable marker of HBV DNA replication
    • Burrell CJ, Gowans EJ, Marmion BP. 1985. High levels of cytoplasmic hepatitis B core antigen as reliable marker of HBV DNA replication. Lancet i:454-455
    • (1985) Lancet , vol.1 , pp. 454-455
    • Burrell, C.J.1    Gowans, E.J.2    Marmion, B.P.3
  • 39
    • 0022377012 scopus 로고
    • Cytoplasmic (but not nuclear) hepatitis B virus (HBV) core antigen reflects HBV DNA synthesis at the level of the infected hepatocyte
    • Gowans EJ, Burrell CJ, Jilbert AR, Marmion BP. 1985. Cytoplasmic (but not nuclear) hepatitis B virus (HBV) core antigen reflects HBV DNA synthesis at the level of the infected hepatocyte. Intervirology 24:220-225. http://dx.doi.org/10.1159/000149646
    • (1985) Intervirology , vol.24 , pp. 220-225
    • Gowans, E.J.1    Burrell, C.J.2    Jilbert, A.R.3    Marmion, B.P.4
  • 40
    • 77956400648 scopus 로고    scopus 로고
    • IFN-αβ and self-MHCdivert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions
    • Marshall HD, Prince AL, Berg LJ, Welsh RM. 2010. IFN-αβ and self-MHCdivert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol 185:1419-1428. http://dx.doi.org/10.4049/jimmunol.1001140
    • (2010) J Immunol , vol.185 , pp. 1419-1428
    • Marshall, H.D.1    Prince, A.L.2    Berg, L.J.3    Welsh, R.M.4
  • 41
    • 84943383941 scopus 로고    scopus 로고
    • Natural killer cell characteristics in patients with chronic hepatitis B virus (HBV) infection are associated with HBV surface antigen clearance after combination treatment with pegylated interferon alfa-2a and adefovir
    • Stelma F, de Niet A, Tempelmans Plat-Sinnige MJ, Jansen L, Takkenberg RB, Reesink HW, Kootstra NA, van Leeuwen EM. 2015. Natural killer cell characteristics in patients with chronic hepatitis B virus (HBV) infection are associated with HBV surface antigen clearance after combination treatment with pegylated interferon alfa-2a and adefovir. J Infect Dis 212:1042-1051. http://dx.doi.org/10.1093/infdis/jiv180
    • (2015) J Infect Dis , vol.212 , pp. 1042-1051
    • Stelma, F.1    de Niet, A.2    Tempelmans Plat-Sinnige, M.J.3    Jansen, L.4    Takkenberg, R.B.5    Reesink, H.W.6    Kootstra, N.A.7    van Leeuwen, E.M.8
  • 42
    • 84921332527 scopus 로고    scopus 로고
    • + T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation
    • + T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation. J Hepatol 61:1212-1219. http://dx.doi.org/10.1016/j.jhep.2014.07.005
    • (2014) J Hepatol , vol.61 , pp. 1212-1219
    • Bengsch, B.1    Martin, B.2    Thimme, R.3
  • 43
    • 84983720423 scopus 로고    scopus 로고
    • PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model
    • Tzeng HT, Tsai HF, Liao HJ, Lin YJ, Chen L, Chen PJ, Hsu PN. 2012. PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model. PLoS One 7:e39179. http://dx.doi.org/10.1371/journal.pone.0039179
    • (2012) PLoS One , vol.7
    • Tzeng, H.T.1    Tsai, H.F.2    Liao, H.J.3    Lin, Y.J.4    Chen, L.5    Chen, P.J.6    Hsu, P.N.7
  • 47
    • 77955236073 scopus 로고    scopus 로고
    • Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression
    • Abad X, Razquin N, Abad A, Fortes P. 2010. Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression. Nucleic Acids Res 38:e136. http://dx.doi.org/10.1093/nar/gkq299
    • (2010) Nucleic Acids Res , vol.38 , pp. e136
    • Abad, X.1    Razquin, N.2    Abad, A.3    Fortes, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.