-
1
-
-
34250819839
-
Intracellular amyloid-beta in Alzheimer’s disease
-
PMID: 17551515
-
LaFerla FM, Green KN, Oddo S. Intracellular amyloid-beta in Alzheimer’s disease. Nat Rev Neurosci. 2007; 8(7):499–509. https://doi.org/10.1038/nrn2168 PMID: 17551515.
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.7
, pp. 499-509
-
-
LaFerla, F.M.1
Green, K.N.2
Oddo, S.3
-
2
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders
-
PMID: 17684513
-
Ballatore C, Lee VM, Trojanowski JQ. Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders. Nat Rev Neurosci. 2007; 8(9):663–72. PMID: 17684513. https://doi.org/10.1038/ nrn2194
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.9
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.2
Trojanowski, J.Q.3
-
3
-
-
34547380204
-
Neuroinflammation in Alzheimer’s disease and Parkinson’s disease: are microglia pathogenic in either disorder?
-
PMID: 17678964
-
Rogers J, Mastroeni D, Leonard B, Joyce J, Grover A. Neuroinflammation in Alzheimer’s disease and Parkinson’s disease: are microglia pathogenic in either disorder? Int Rev Neurobiol. 2007; 82:235–46. PMID: 17678964. https://doi.org/10.1016/S0074-7742(07)82012-5
-
(2007)
Int Rev Neurobiol
, vol.82
, pp. 235-246
-
-
Rogers, J.1
Mastroeni, D.2
Leonard, B.3
Joyce, J.4
Grover, A.5
-
4
-
-
84875655895
-
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature
-
PMID: 22315714
-
Wyss-Coray T, Rogers J. Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med. 2013; 2(1):a006346. PMID: 22315714. https://doi.org/10.1101/cshperspect.a006346
-
(2013)
Cold Spring Harb Perspect Med
, vol.2
, Issue.1
, pp. a006346
-
-
Wyss-Coray, T.1
Rogers, J.2
-
5
-
-
84864134469
-
Microglia function in Alzheimer’s disease
-
PMID: 22363284
-
Solito E, Sastre M. Microglia function in Alzheimer’s disease. Front Pharmacol. 3:14. PMID: 22363284. https://doi.org/10.3389/fphar.2012.00014
-
Front Pharmacol
, vol.3
, pp. 14
-
-
Solito, E.1
Sastre, M.2
-
6
-
-
76549104226
-
Neuroinflammation—An early event in both the history and pathogenesis of Alzheimer’s disease
-
PMID: 20160456
-
Eikelenboom P, van Exel E, Hoozemans JJ, Veerhuis R, Rozemuller AJ, van Gool WA. Neuroinflammation—an early event in both the history and pathogenesis of Alzheimer’s disease. Neurodegener Dis. 2010; 7(1–3):38–41. PMID: 20160456. https://doi.org/10.1159/000283480
-
(2010)
Neurodegener Dis
, vol.7
, Issue.1-3
, pp. 38-41
-
-
Eikelenboom, P.1
Van Exel, E.2
Hoozemans, J.J.3
Veerhuis, R.4
Rozemuller, A.J.5
Van Gool, W.A.6
-
7
-
-
84871922036
-
Deciphering the mechanism underlying late-onset Alzheimer disease
-
PMID: 23183882
-
Krstic D, Knuesel I. Deciphering the mechanism underlying late-onset Alzheimer disease. Nat Rev Neurol. 2013; 9(1):25–34. PMID: 23183882. https://doi.org/10.1038/nrneurol.2012.236
-
(2013)
Nat Rev Neurol
, vol.9
, Issue.1
, pp. 25-34
-
-
Krstic, D.1
Knuesel, I.2
-
8
-
-
0030250567
-
Inflammation and Alzheimer’s disease pathogenesis
-
PMID: 8892340
-
Rogers J, Webster S, Lue LF, Brachova L, Civin WH, Emmerling M, et al. Inflammation and Alzheimer’s disease pathogenesis. Neurobiol Aging. 1996; 17(5):681–6. PMID: 8892340.
-
(1996)
Neurobiol Aging
, vol.17
, Issue.5
, pp. 681-686
-
-
Rogers, J.1
Webster, S.2
Lue, L.F.3
Brachova, L.4
Civin, W.H.5
Emmerling, M.6
-
9
-
-
84973308454
-
Genetic variations underlying Alzheimer’s disease: Evidence from genome-wide association studies and beyond
-
PMID: 27302364
-
Cuyvers E, Sleegers K. Genetic variations underlying Alzheimer’s disease: evidence from genome-wide association studies and beyond. Lancet Neurol. 2016; 15(8):857–68. https://doi.org/10.1016/ S1474-4422(16)00127-7 PMID: 27302364.
-
(2016)
Lancet Neurol
, vol.15
, Issue.8
, pp. 857-868
-
-
Cuyvers, E.1
Sleegers, K.2
-
10
-
-
40249108385
-
Functional role of proteins containing ankyrin repeats
-
PMID: 18318217
-
Voronin DA, Kiseleva EV. [Functional role of proteins containing ankyrin repeats]. Tsitologiia. 2007; 49 (12):989–99. PMID: 18318217.
-
(2007)
Tsitologiia
, vol.49
, Issue.12
, pp. 989-999
-
-
Voronin, D.A.1
Kiseleva, E.V.2
-
11
-
-
84919784465
-
Alzheimer’s disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
-
PMID: 25129075; PubMed Central PMCID: PMCPMC4292795
-
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, et al. Alzheimer’s disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci. 2014; 17 (9):1156–63. https://doi.org/10.1038/nn.3786 PMID: 25129075; PubMed Central PMCID: PMCPMC4292795.
-
(2014)
Nat Neurosci
, vol.17
, Issue.9
, pp. 1156-1163
-
-
De Jager, P.L.1
Srivastava, G.2
Lunnon, K.3
Burgess, J.4
Schalkwyk, L.C.5
Yu, L.6
-
12
-
-
84906716826
-
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer’s disease
-
PMID: 25129077; PubMed Central PMCID: PMCPMC4410018
-
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer’s disease. Nat Neurosci. 2014; 17(9):1164–70. https://doi.org/10.1038/nn.3782 PMID: 25129077; PubMed Central PMCID: PMCPMC4410018.
-
(2014)
Nat Neurosci
, vol.17
, Issue.9
, pp. 1164-1170
-
-
Lunnon, K.1
Smith, R.2
Hannon, E.3
De Jager, P.L.4
Srivastava, G.5
Volta, M.6
-
13
-
-
84948404988
-
Association of single-nucleotide polymorphism in ANK1 with late-onset Alzheimer’s disease in han Chinese
-
PMID: 26611832
-
Chi S, Song JH, Tan MS, Zhang W, Wang ZX, Jiang T, et al. Association of Single-Nucleotide Polymorphism in ANK1 with Late-Onset Alzheimer’s Disease in Han Chinese. Mol Neurobiol. 2015. https://doi.org/10.1007/s12035-015-9547-x PMID: 26611832.
-
(2015)
Mol Neurobiol
-
-
Chi, S.1
Song, J.H.2
Tan, M.S.3
Zhang, W.4
Wang, Z.X.5
Jiang, T.6
-
14
-
-
84863503465
-
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations
-
PMID: 22456796
-
Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T, et al. A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet. 2012; 21(13):3042–9. https://doi.org/10.1093/hmg/dds113 PMID: 22456796.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.13
, pp. 3042-3049
-
-
Imamura, M.1
Maeda, S.2
Yamauchi, T.3
Hara, K.4
Yasuda, K.5
Morizono, T.6
-
15
-
-
84876219189
-
Type 2 diabetes risk alleles near bcar1 and in ank1 associate with decreased beta-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the danish inter99 cohort
-
PMID: 23457408
-
Harder MN, Ribel-Madsen R, Justesen JM, Sparso T, Andersson EA, Grarup N, et al. Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased beta-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort. J Clin Endocrinol Metab. 2013; 98(4):E801–6. https://doi.org/10.1210/jc.2012-4169 PMID: 23457408.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.4
, pp. E801-E806
-
-
Harder, M.N.1
Ribel-Madsen, R.2
Justesen, J.M.3
Sparso, T.4
Andersson, E.A.5
Grarup, N.6
-
16
-
-
0842309993
-
Increased risk of type 2 diabetes in Alzheimer disease
-
PMID: 14747300
-
Janson J, Laedtke T, Parisi JE, O’Brien P, Petersen RC, Butler PC. Increased risk of type 2 diabetes in Alzheimer disease. Diabetes. 2004; 53(2):474–81. PMID: 14747300.
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 474-481
-
-
Janson, J.1
Laedtke, T.2
Parisi, J.E.3
O’Brien, P.4
Petersen, R.C.5
Butler, P.C.6
-
17
-
-
65449136284
-
Tophat: Discovering splice junctions with RNA-seq
-
PMID: 19289445; PubMed Central PMCID: PMC2672628
-
Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics. 2009; 25(9):1105–11. https://doi.org/10.1093/bioinformatics/btp120 PMID: 19289445; PubMed Central PMCID: PMC2672628.
-
(2009)
Bioinformatics
, vol.25
, Issue.9
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
18
-
-
84859885816
-
Differential gene and transcript expression analysis of RNA-seq experiments with tophat and cufflinks
-
PMID: 22383036; PubMed Central PMCID: PMC3334321
-
Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nature protocols. 2012; 7(3):562–78. https://doi.org/10.1038/nprot.2012.016 PMID: 22383036; PubMed Central PMCID: PMC3334321.
-
(2012)
Nature Protocols
, vol.7
, Issue.3
, pp. 562-578
-
-
Trapnell, C.1
Roberts, A.2
Goff, L.3
Pertea, G.4
Kim, D.5
Kelley, D.R.6
-
19
-
-
84875262338
-
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer’s disease
-
PMID: 23273601; PubMed Central PMCID: PMCPMC4022280
-
Berchtold NC, Coleman PD, Cribbs DH, Rogers J, Gillen DL, Cotman CW. Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer’s disease. Neurobiol Aging. 2013; 34(6):1653–61. https://doi.org/10.1016/j.neurobiolaging.2012.11.024 PMID: 23273601; PubMed Central PMCID: PMCPMC4022280.
-
(2013)
Neurobiol Aging
, vol.34
, Issue.6
, pp. 1653-1661
-
-
Berchtold, N.C.1
Coleman, P.D.2
Cribbs, D.H.3
Rogers, J.4
Gillen, D.L.5
Cotman, C.W.6
-
20
-
-
84902085333
-
Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer’s disease
-
PMID: 24786631; PubMed Central PMCID: PMCPMC4067010
-
Berchtold NC, Sabbagh MN, Beach TG, Kim RC, Cribbs DH, Cotman CW. Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer’s disease. Neurobiol Aging. 2014; 35(9):1961–72. https://doi.org/10.1016/j.neurobiolaging.2014.03.031 PMID: 24786631; PubMed Central PMCID: PMCPMC4067010.
-
(2014)
Neurobiol Aging
, vol.35
, Issue.9
, pp. 1961-1972
-
-
Berchtold, N.C.1
Sabbagh, M.N.2
Beach, T.G.3
Kim, R.C.4
Cribbs, D.H.5
Cotman, C.W.6
-
21
-
-
84959377661
-
Novel role of src in priming Pyk2 phosphorylation
-
PMID: 26866924; PubMed Central PMCID: PMCPMC4750869
-
Zhao M, Finlay D, Zharkikh I, Vuori K. Novel Role of Src in Priming Pyk2 Phosphorylation. PLoS One. 2016; 11(2):e0149231. https://doi.org/10.1371/journal.pone.0149231 PMID: 26866924; PubMed Central PMCID: PMCPMC4750869.
-
(2016)
Plos One
, vol.11
, Issue.2
, pp. e0149231
-
-
Zhao, M.1
Finlay, D.2
Zharkikh, I.3
Vuori, K.4
-
22
-
-
84952785324
-
Ganglioside gq1b induces dopamine release through the activation of Pyk2
-
PMID: 26704905
-
Zhang Z, Chu SF, Mou Z, Gao Y, Wang ZZ, Wei GN, et al. Ganglioside GQ1b induces dopamine release through the activation of Pyk2. Mol Cell Neurosci. 2016; 71:102–13. https://doi.org/10.1016/j.mcn.2015.12.009 PMID: 26704905.
-
(2016)
Mol Cell Neurosci
, vol.71
, pp. 102-113
-
-
Zhang, Z.1
Chu, S.F.2
Mou, Z.3
Gao, Y.4
Wang, Z.Z.5
Wei, G.N.6
-
23
-
-
84960349024
-
Structural basis for the interaction between Pyk2-fat domain and leupaxin ld repeats
-
PMID: 26866573; PubMed Central PMCID: PMCPMC4843776
-
Vanarotti MS, Finkelstein DB, Guibao CD, Nourse A, Miller DJ, Zheng JJ. Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry. 2016; 55(9):1332–45. https://doi.org/10.1021/acs.biochem.5b01274 PMID: 26866573; PubMed Central PMCID: PMCPMC4843776.
-
(2016)
Biochemistry
, vol.55
, Issue.9
, pp. 1332-1345
-
-
Vanarotti, M.S.1
Finkelstein, D.B.2
Guibao, C.D.3
Nourse, A.4
Miller, D.J.5
Zheng, J.J.6
-
24
-
-
84951838660
-
Cd19 controls toll-like receptor 9 responses in human B cells
-
e6. PMID: 26478008; PubMed Central PMCID: PMCPMC4783287
-
Morbach H, Schickel JN, Cunningham-Rundles C, Conley ME, Reisli I, Franco JL, et al. CD19 controls Toll-like receptor 9 responses in human B cells. J Allergy Clin Immunol. 2016; 137(3):889–98 e6. https://doi.org/10.1016/j.jaci.2015.08.040 PMID: 26478008; PubMed Central PMCID: PMCPMC4783287.
-
(2016)
J Allergy Clin Immunol
, vol.137
, Issue.3
, pp. 889-898
-
-
Morbach, H.1
Schickel, J.N.2
Cunningham-Rundles, C.3
Conley, M.E.4
Reisli, I.5
Franco, J.L.6
-
25
-
-
84983373722
-
Subcellular localization of Pyk2 during oocyte fertilization and early-embryo development in mice
-
PMID: 27086609
-
Meng XQ, Dai YY, Jing LD, Bai J, Liu SZ, Zheng KG, et al. Subcellular localization of Pyk2 during oocyte fertilization and early-embryo development in mice. J Reprod Dev. 2016. https://doi.org/10.1262/jrd. 2016-015 PMID: 27086609.
-
(2016)
J Reprod Dev
-
-
Meng, X.Q.1
Dai, Y.Y.2
Jing, L.D.3
Bai, J.4
Liu, S.Z.5
Zheng, K.G.6
-
26
-
-
84957956929
-
Notch2 signaling promotes osteoclast resorption via activation of Pyk2
-
PMID: 26829213
-
Jin WJ, Kim B, Kim JW, Kim HH, Ha H, Lee ZH. Notch2 signaling promotes osteoclast resorption via activation of PYK2. Cell Signal. 2016; 28(5):357–65. https://doi.org/10.1016/j.cellsig.2016.01.016PMID: 26829213.
-
(2016)
Cell Signal
, vol.28
, Issue.5
, pp. 357-365
-
-
Jin, W.J.1
Kim, B.2
Kim, J.W.3
Kim, H.H.4
Ha, H.5
Lee, Z.H.6
-
27
-
-
84958765684
-
Pyk2 is essential for astrocytes mobility following brain lesion
-
PMID: 26663135
-
Giralt A, Coura R, Girault JA. Pyk2 is essential for astrocytes mobility following brain lesion. Glia. 2016; 64(4):620–34. https://doi.org/10.1002/glia.22952 PMID: 26663135.
-
(2016)
Glia
, vol.64
, Issue.4
, pp. 620-634
-
-
Giralt, A.1
Coura, R.2
Girault, J.A.3
-
28
-
-
84962261839
-
Pyk2 and megakaryocytes regulate osteoblast differentiation and migration via distinct and overlapping mechanisms
-
PMID: 26552846; PubMed Central PMCID: PMCPMC4821770
-
Eleniste PP, Patel V, Posritong S, Zero O, Largura H, Cheng YH, et al. Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Migration Via Distinct and Overlapping Mechanisms. J Cell Bio-chem. 2016; 117(6):1396–406. https://doi.org/10.1002/jcb.25430 PMID: 26552846; PubMed Central PMCID: PMCPMC4821770.
-
(2016)
J Cell Bio-chem
, vol.117
, Issue.6
, pp. 1396-1406
-
-
Eleniste, P.P.1
Patel, V.2
Posritong, S.3
Zero, O.4
Largura, H.5
Cheng, Y.H.6
-
29
-
-
84884759753
-
Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer
-
PMID: 23938249
-
Kulis M, Queiros AC, Beekman R, Martin-Subero JI. Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer. Biochim Biophys Acta. 2013; 1829(11):1161–74. https://doi.org/10.1016/j.bbagrm.2013.08.001 PMID: 23938249.
-
(2013)
Biochim Biophys Acta
, vol.1829
, Issue.11
, pp. 1161-1174
-
-
Kulis, M.1
Queiros, A.C.2
Beekman, R.3
Martin-Subero, J.I.4
-
30
-
-
84933502183
-
The regulatory mechanisms of intragenic DNA methylation
-
PMID: 26111026
-
Lee SM, Choi WY, Lee J, Kim YJ. The regulatory mechanisms of intragenic DNA methylation. Epige-nomics. 2015; 7(4):527–31. https://doi.org/10.2217/epi.15.38 PMID: 26111026.
-
(2015)
Epige-nomics
, vol.7
, Issue.4
, pp. 527-531
-
-
Lee, S.M.1
Choi, W.Y.2
Lee, J.3
Kim, Y.J.4
-
31
-
-
84945966093
-
Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation
-
PMID: 26510686; PubMed Central PMCID: PMCPMC4625569
-
Rauscher GH, Kresovich JK, Poulin M, Yan L, Macias V, Mahmoud AM, et al. Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation. BMC Cancer. 2015; 15:816. https://doi.org/10.1186/s12885-015-1777-9 PMID: 26510686; PubMed Central PMCID: PMCPMC4625569.
-
(2015)
BMC Cancer
, vol.15
, pp. 816
-
-
Rauscher, G.H.1
Kresovich, J.K.2
Poulin, M.3
Yan, L.4
Macias, V.5
Mahmoud, A.M.6
|