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Volumn 8, Issue 1, 2017, Pages

Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HISTONE H3K4ME3; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; TRITHORAX GROUP; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; HISTONE; PRC1 PROTEIN, HUMAN;

EID: 85034668683     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-01679-x     Document Type: Article
Times cited : (9)

References (70)
  • 1
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein, B. E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006).
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1
  • 2
    • 55449105221 scopus 로고    scopus 로고
    • Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
    • Ku, M. et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 4, e1000242 (2008).
    • (2008) PLoS Genet. , vol.4 , pp. e1000242
    • Ku, M.1
  • 3
    • 34548434716 scopus 로고    scopus 로고
    • Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
    • Pan, G. et al. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1, 299-312 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 299-312
    • Pan, G.1
  • 4
    • 34548424709 scopus 로고    scopus 로고
    • Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells
    • Zhao, X. D. et al. Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell 1, 286-298 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 286-298
    • Zhao, X.D.1
  • 5
    • 33646872978 scopus 로고    scopus 로고
    • Chromatin signatures of pluripotent cell lines
    • Azuara, V. et al. Chromatin signatures of pluripotent cell lines. Nat. Cell Biol. 8, 532-538 (2006).
    • (2006) Nat. Cell Biol. , vol.8 , pp. 532-538
    • Azuara, V.1
  • 6
    • 20444397430 scopus 로고    scopus 로고
    • Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
    • Dou, Y. et al. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121, 873-885 (2005).
    • (2005) Cell , vol.121 , pp. 873-885
    • Dou, Y.1
  • 7
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P. &Reinberg, D. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16, 2893-2905 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 8
    • 20444417108 scopus 로고    scopus 로고
    • WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development
    • Wysocka, J. et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121, 859-872 (2005).
    • (2005) Cell , vol.121 , pp. 859-872
    • Wysocka, J.1
  • 9
    • 84856756676 scopus 로고    scopus 로고
    • Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs
    • Brookes, E. et al. Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell 10, 157-170 (2012).
    • (2012) Cell Stem Cell , vol.10 , pp. 157-170
    • Brookes, E.1
  • 10
    • 79954562232 scopus 로고    scopus 로고
    • Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells
    • Min, I. M. et al. Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes Dev. 25, 742-754 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 742-754
    • Min, I.M.1
  • 11
    • 36749089980 scopus 로고    scopus 로고
    • Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
    • Stock, J. K. et al. Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat. Cell Biol. 9, 1428-1435 (2007).
    • (2007) Nat. Cell Biol. , vol.9 , pp. 1428-1435
    • Stock, J.K.1
  • 12
    • 84871586080 scopus 로고    scopus 로고
    • A molecular roadmap of reprogramming somatic cells into iPS Cells
    • Polo Jose, M. et al. A molecular roadmap of reprogramming somatic cells into iPS Cells. Cell 151, 1617-1632 (2012).
    • (2012) Cell , vol.151 , pp. 1617-1632
    • Polo, J.M.1
  • 13
    • 0035674146 scopus 로고    scopus 로고
    • Cell and tissue requirements for the gene eed during mouse gastrulation and organogenesis
    • Morin-Kensicki, E. M., Faust, C., LaMantia, C. &Magnuson, T. Cell and tissue requirements for the gene eed during mouse gastrulation and organogenesis. Genesis 31, 142-146 (2001).
    • (2001) Genesis , vol.31 , pp. 142-146
    • Morin-Kensicki, E.M.1    Faust, C.2    LaMantia, C.3    Magnuson, T.4
  • 14
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini, D., Bracken, A. P., Jensen, M. R., Lazzerini Denchi, E. &Helin, K. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23, 4061-4071 (2004).
    • (2004) EMBO J. , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini, D.E.4    Helin, K.5
  • 15
    • 0034977239 scopus 로고    scopus 로고
    • The polycomb-group gene Ezh2 is required for early mouse development
    • O'Carroll, D. et al. The polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell Biol. 21, 4330-4336 (2001).
    • (2001) Mol. Cell Biol. , vol.21 , pp. 4330-4336
    • O'Carroll, D.1
  • 16
    • 80053201511 scopus 로고    scopus 로고
    • 3D-image analysis platform monitoring relocation of pluripotency genes during reprogramming
    • Jost, K. L. et al. 3D-image analysis platform monitoring relocation of pluripotency genes during reprogramming. Nucleic Acids Res. 39, e113 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. e113
    • Jost, K.L.1
  • 17
    • 84887852466 scopus 로고    scopus 로고
    • Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming
    • Apostolou, E. et al. Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. Cell Stem Cell 12, 699-712 (2013).
    • (2013) Cell Stem Cell , vol.12 , pp. 699-712
    • Apostolou, E.1
  • 18
    • 84855297335 scopus 로고    scopus 로고
    • A decade of 3C technologies: Insights into nuclear organization
    • de Wit, E. &de Laat, W. A decade of 3C technologies: insights into nuclear organization. Genes Dev. 26, 11-24 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 11-24
    • De Wit, E.1    De Laat, W.2
  • 19
    • 80555154012 scopus 로고    scopus 로고
    • Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method
    • Gheldof, N., Leleu, M., Noordermeer, D., Rougemont, J. &Reymond, A. Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method. Methods Mol. Biol. 786, 211-225 (2012).
    • (2012) Methods Mol. Biol. , vol.786 , pp. 211-225
    • Gheldof, N.1    Leleu, M.2    Noordermeer, D.3    Rougemont, J.4    Reymond, A.5
  • 20
    • 33750212321 scopus 로고    scopus 로고
    • Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
    • Simonis, M. et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat. Genet. 38, 1348-1354 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 1348-1354
    • Simonis, M.1
  • 21
    • 33750203582 scopus 로고    scopus 로고
    • Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra-and interchromosomal interactions
    • Zhao, Z. et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra-and interchromosomal interactions. Nat. Genet. 38, 1341-1347 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 1341-1347
    • Zhao, Z.1
  • 22
    • 70349873824 scopus 로고    scopus 로고
    • Comprehensive mapping of long-range interactions reveals folding principles of the human genome
    • Lieberman-Aiden, E. et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 326, 289-293 (2009).
    • (2009) Science , vol.326 , pp. 289-293
    • Lieberman-Aiden, E.1
  • 23
    • 0028990259 scopus 로고
    • Splinkerettes-improved vectorettes for greater efficiency in PCR walking
    • Devon, R. S., Porteous, D. J. &Brookes, A. J. Splinkerettes-improved vectorettes for greater efficiency in PCR walking. Nucleic Acids Res. 23, 1644-1645 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1644-1645
    • Devon, R.S.1    Porteous, D.J.2    Brookes, A.J.3
  • 24
    • 84876516886 scopus 로고    scopus 로고
    • Protocol: Sonication-based circular chromosome conformation capture with next-generation sequencing analysis for the detection of chromatin interactions
    • Huang, P. Y. H. et al. Protocol: sonication-based circular chromosome conformation capture with next-generation sequencing analysis for the detection of chromatin interactions. Protoc. Exch., doi: https://doi.org/10.1038/ protex.2010.1207 (2010).
    • (2010) Protoc. Exch.
    • Huang, P.Y.H.1
  • 25
    • 84875143934 scopus 로고    scopus 로고
    • Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions
    • Stadhouders, R. et al. Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions. Nat. Protoc. 8, 509-524 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 509-524
    • Stadhouders, R.1
  • 26
    • 84887835943 scopus 로고    scopus 로고
    • Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency
    • Wei, Z. et al. Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency. Cell Stem Cell 13, 36-47 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 36-47
    • Wei, Z.1
  • 27
    • 84857707318 scopus 로고    scopus 로고
    • ChromHMM: Automating chromatin-state discovery and characterization
    • Ernst, J. &Kellis, M. ChromHMM: automating chromatin-state discovery and characterization. Nat. Methods 9, 215-216 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 215-216
    • Ernst, J.1    Kellis, M.2
  • 28
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst, J. et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49 (2011).
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1
  • 29
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium
    • ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
    • (2012) Nature , vol.489 , pp. 57-74
  • 30
    • 34547624303 scopus 로고    scopus 로고
    • Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560 (2007).
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1
  • 31
    • 84879260661 scopus 로고    scopus 로고
    • A double take on bivalent promoters
    • Voigt, P., Tee, W. W. &Reinberg, D. A double take on bivalent promoters. Genes Dev. 27, 1318-1338 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 1318-1338
    • Voigt, P.1    Tee, W.W.2    Reinberg, D.3
  • 32
    • 84862000566 scopus 로고    scopus 로고
    • Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells
    • Drukker, M. et al. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat. Biotechnol. 30, 531-542 (2012).
    • (2012) Nat. Biotechnol. , vol.30 , pp. 531-542
    • Drukker, M.1
  • 33
    • 84875804538 scopus 로고    scopus 로고
    • Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres
    • Albini, S. et al. Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres. Cell Rep. 3, 661-670 (2013).
    • (2013) Cell Rep. , vol.3 , pp. 661-670
    • Albini, S.1
  • 34
    • 79952161362 scopus 로고    scopus 로고
    • FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation
    • Yu, P., Pan, G., Yu, J. &Thomson, J. A. FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell 8, 326-334 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 326-334
    • Yu, P.1    Pan, G.2    Yu, J.3    Thomson, J.A.4
  • 35
    • 78649647544 scopus 로고    scopus 로고
    • A mesoderm-derived precursor for mesenchymal stem and endothelial cells
    • Vodyanik, M. A. et al. A mesoderm-derived precursor for mesenchymal stem and endothelial cells. Cell Stem Cell 7, 718-729 (2010).
    • (2010) Cell Stem Cell , vol.7 , pp. 718-729
    • Vodyanik, M.A.1
  • 37
    • 84870310006 scopus 로고    scopus 로고
    • Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation
    • Splinter, E., de Wit, E., van de Werken, H. J., Klous, P. &de Laat, W. Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation. Methods 58, 221-230 (2012).
    • (2012) Methods , vol.58 , pp. 221-230
    • Splinter, E.1    De Wit, E.2    Van De Werken, H.J.3    Klous, P.4    De Laat, W.5
  • 38
    • 77952576224 scopus 로고    scopus 로고
    • Molecular maps of the reorganization of genomenuclear lamina interactions during differentiation
    • Peric-Hupkes, D. et al. Molecular maps of the reorganization of genomenuclear lamina interactions during differentiation. Mol. Cell 38, 603-613 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 603-613
    • Peric-Hupkes, D.1
  • 39
    • 41949121084 scopus 로고    scopus 로고
    • Recruitment to the nuclear periphery can alter expression of genes in human cells
    • Finlan, L. E. et al. Recruitment to the nuclear periphery can alter expression of genes in human cells. PLoS Genet. 4, e1000039 (2008).
    • (2008) PLoS Genet. , vol.4 , pp. e1000039
    • Finlan, L.E.1
  • 40
    • 84873375779 scopus 로고    scopus 로고
    • Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence
    • Meuleman, W. et al. Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence. Genome Res. 23, 270-280 (2013).
    • (2013) Genome Res. , vol.23 , pp. 270-280
    • Meuleman, W.1
  • 41
    • 45149084413 scopus 로고    scopus 로고
    • Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
    • Guelen, L. et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 453, 948-951 (2008).
    • (2008) Nature , vol.453 , pp. 948-951
    • Guelen, L.1
  • 42
    • 40749122641 scopus 로고    scopus 로고
    • Transcriptional repression mediated by repositioning of genes to the nuclear lamina
    • Reddy, K. L., Zullo, J. M., Bertolino, E. &Singh, H. Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature 452, 243-247 (2008).
    • (2008) Nature , vol.452 , pp. 243-247
    • Reddy, K.L.1    Zullo, J.M.2    Bertolino, E.3    Singh, H.4
  • 43
    • 70350349888 scopus 로고    scopus 로고
    • The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment
    • Luo, L. et al. The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment. J. Cell Sci. 122, 3729-3737 (2009).
    • (2009) J. Cell Sci. , vol.122 , pp. 3729-3737
    • Luo, L.1
  • 44
    • 84886777912 scopus 로고    scopus 로고
    • Chromosomal contact permits transcription between coregulated genes
    • Fanucchi, S., Shibayama, Y., Burd, S., Weinberg, M. S. &Mhlanga, M. M. Chromosomal contact permits transcription between coregulated genes. Cell 155, 606-620 (2013).
    • (2013) Cell , vol.155 , pp. 606-620
    • Fanucchi, S.1    Shibayama, Y.2    Burd, S.3    Weinberg, M.S.4    Mhlanga, M.M.5
  • 45
    • 0029973080 scopus 로고    scopus 로고
    • Active RNA polymerases are localized within discrete transcription "factories' in human nuclei
    • Iborra, F. J., Pombo, A., Jackson, D. A. &Cook, P. R. Active RNA polymerases are localized within discrete transcription "factories' in human nuclei. J. Cell Sci. 109, 1427-1436 (1996).
    • (1996) J. Cell Sci. , vol.109 , pp. 1427-1436
    • Iborra, F.J.1    Pombo, A.2    Jackson, D.A.3    Cook, P.R.4
  • 46
    • 0027499230 scopus 로고
    • Visualization of focal sites of transcription within human nuclei
    • Jackson, D. A., Hassan, A. B., Errington, R. J. &Cook, P. R. Visualization of focal sites of transcription within human nuclei. EMBO J. 12, 1059-1065 (1993).
    • (1993) EMBO J. , vol.12 , pp. 1059-1065
    • Jackson, D.A.1    Hassan, A.B.2    Errington, R.J.3    Cook, P.R.4
  • 47
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther, M. G., Levine, S. S., Boyer, L. A., Jaenisch, R. &Young, R. A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130, 77-88 (2007).
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 48
    • 84878282421 scopus 로고    scopus 로고
    • Epigenomic analysis of multilineage differentiation of human embryonic stem cells
    • Xie, W. et al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell 153, 1134-1148 (2013).
    • (2013) Cell , vol.153 , pp. 1134-1148
    • Xie, W.1
  • 49
    • 84940023613 scopus 로고    scopus 로고
    • Comparison of Hi-C results using in-solution versus innucleus ligation
    • Nagano, T. et al. Comparison of Hi-C results using in-solution versus innucleus ligation. Genome Biol. 16, 175 (2015).
    • (2015) Genome Biol. , vol.16 , pp. 175
    • Nagano, T.1
  • 50
    • 84976871478 scopus 로고    scopus 로고
    • UMI-4C for quantitative and targeted chromosomal contact profiling
    • Schwartzman, O. et al. UMI-4C for quantitative and targeted chromosomal contact profiling. Nat. Methods 13, 685-691 (2016).
    • (2016) Nat. Methods , vol.13 , pp. 685-691
    • Schwartzman, O.1
  • 51
    • 84948470821 scopus 로고    scopus 로고
    • MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells
    • Fu, Y. et al. MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells. Sci. Rep. 5, 17186 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 17186
    • Fu, Y.1
  • 52
    • 84882642434 scopus 로고    scopus 로고
    • Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence
    • Sadaie, M. et al. Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence. Genes Dev. 27, 1800-1808 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 1800-1808
    • Sadaie, M.1
  • 53
    • 85027929606 scopus 로고    scopus 로고
    • Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization
    • Denholtz, M. et al. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell 13, 602-616 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 602-616
    • Denholtz, M.1
  • 54
    • 84952022547 scopus 로고    scopus 로고
    • Dynamic reorganization of extremely long-range promoterpromoter interactions between two states of pluripotency
    • Joshi, O. et al. Dynamic reorganization of extremely long-range promoterpromoter interactions between two states of pluripotency. Cell Stem Cell 17, 748-757 (2015).
    • (2015) Cell Stem Cell , vol.17 , pp. 748-757
    • Joshi, O.1
  • 55
    • 84942852834 scopus 로고    scopus 로고
    • Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome
    • Schoenfelder, S. et al. Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome. Nat. Genet. 47, 1179-1186 (2015).
    • (2015) Nat. Genet. , vol.47 , pp. 1179-1186
    • Schoenfelder, S.1
  • 56
    • 84879695128 scopus 로고    scopus 로고
    • Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
    • Li, W. et al. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature 498, 516-520 (2013).
    • (2013) Nature , vol.498 , pp. 516-520
    • Li, W.1
  • 57
    • 84874368349 scopus 로고    scopus 로고
    • Activating RNAs associate with mediator to enhance chromatin architecture and transcription
    • Lai, F. et al. Activating RNAs associate with mediator to enhance chromatin architecture and transcription. Nature 494, 497-501 (2013).
    • (2013) Nature , vol.494 , pp. 497-501
    • Lai, F.1
  • 58
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • Wang, K. C. et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 472, 120-124 (2011).
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1
  • 59
    • 84874025014 scopus 로고    scopus 로고
    • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-gamma locus
    • Gomez, J. A. et al. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-gamma locus. Cell 152, 743-754 (2013).
    • (2013) Cell , vol.152 , pp. 743-754
    • Gomez, J.A.1
  • 60
    • 84898723075 scopus 로고    scopus 로고
    • Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency
    • Yang, Y. W. et al. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife 3, e02046 (2014).
    • (2014) Elife , vol.3 , pp. e02046
    • Yang, Y.W.1
  • 61
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer, L. A. et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441, 349-353 (2006).
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1
  • 62
    • 79954414897 scopus 로고    scopus 로고
    • Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
    • Ang, Y. S. et al. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145, 183-197 (2011).
    • (2011) Cell , vol.145 , pp. 183-197
    • Ang, Y.S.1
  • 63
    • 84989172058 scopus 로고    scopus 로고
    • Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos
    • Liu, X. et al. Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos. Nature 537, 558-562 (2016).
    • (2016) Nature , vol.537 , pp. 558-562
    • Liu, X.1
  • 64
    • 84979788948 scopus 로고    scopus 로고
    • Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity
    • Nishizawa, M. et al. Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity. Cell Stem Cell 19, 341-354 (2016).
    • (2016) Cell Stem Cell , vol.19 , pp. 341-354
    • Nishizawa, M.1
  • 65
    • 79955634826 scopus 로고    scopus 로고
    • A more efficient method to generate integration-free human iPS cells
    • Okita, K. et al. A more efficient method to generate integration-free human iPS cells. Nat. Methods 8, 409-412 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 409-412
    • Okita, K.1
  • 66
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen, K. et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770 (2009).
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1
  • 68
    • 80255127234 scopus 로고    scopus 로고
    • Cutadapt removes adapter sequences from high-throughput sequencing reads
    • Martin, M. Cutadapt removes adapter sequences from high-throughput sequencing reads. EMBnet J. 17, 10-12 (2011).
    • (2011) EMBnet J. , vol.17 , pp. 10-12
    • Martin, M.1
  • 69
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H. &Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 70
    • 84875700725 scopus 로고    scopus 로고
    • Predicting the molecular complexity of sequencing libraries
    • Daley, T. &Smith, A. D. Predicting the molecular complexity of sequencing libraries. Nat. Methods 10, 325-327 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 325-327
    • Daley, T.1    Smith, A.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.