Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity

Cell Stem Cell

Volumn 19, Issue 3, 2016, Pages 341-354

  Nishizawa, Masatoshi ^a,b   Chonabayashi, Kazuhisa ^a,b   Nomura, Masaki ^a   Tanaka, Azusa ^a   Nakamura, Masahiro ^a   Inagaki, Azusa ^a   Nishikawa, Misato ^a   Takei, Ikue ^a   Oishi, Akiko ^a   Tanabe, Koji ^a   Ohnuki, Mari ^a   Yokota, Hidaka ^a   Koyanagi Aoi, Michiyo ^a   Okita, Keisuke ^a   Watanabe, Akira ^a,c   Takaori Kondo, Akifumi ^b   Yamanaka, Shinya ^a,c,d   Yoshida, Yoshinori ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

chromatin accessibility; DNA methylation; hematopoietic differentiation; human induced pluripotent stem cell; insulin like growth factor 2; mRNA microarray; reprogramming related DNA methylation

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; CD34 ANTIGEN; CD38 ANTIGEN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; LEUKOSIALIN; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR RUNX1; ACTIVIN; CHROMATIN; TRIPARTITE MOTIF PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CHROMATIN; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EMBRYONIC STEM CELL; ENGRAFTMENT; EPIGENETICS; ERYTHROID CELL; ERYTHROPOIESIS; GENE EXPRESSION; GENETIC VARIATION; HEMATOPOIESIS; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; MEGAKARYOCYTE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; CELL LINEAGE; CHEMISTRY; CYTOLOGY; GENE REGULATORY NETWORK; GENETIC EPIGENESIS; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; NUCLEOTIDE SEQUENCE; SCID MOUSE; STEM CELL TRANSPLANTATION;

ACTIVINS; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELLULAR REPROGRAMMING; CHROMATIN; DNA METHYLATION; EPIGENESIS, GENETIC; ERYTHROID CELLS; FIBROBLAST GROWTH FACTORS; GENE REGULATORY NETWORKS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INSULIN-LIKE GROWTH FACTOR II; MEGAKARYOCYTES; MICE, SCID; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; TRIPARTITE MOTIF PROTEINS;

EID: 84979788948     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.06.019     Document Type: Article

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