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Volumn 191, Issue 3, 2018, Pages 268-278

Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation

Author keywords

alum; neonatal sepsis; NETs; phagocytosis

Indexed keywords

ALUMINUM POTASSIUM SULFATE; B7 ANTIGEN; CASPASE 11; CD86 ANTIGEN; IMJECT; INFLAMMASOME; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUKOCYTE ELASTASE; PHORBOL ESTER DERIVATIVE; RAG1 PROTEIN; ALUMINUM SULFATE; BACTERIAL VACCINE; CASP11 PROTEIN, MOUSE; CASPASE; IMMUNOLOGICAL ADJUVANT;

EID: 85034250713     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.13072     Document Type: Article
Times cited : (15)

References (41)
  • 1
    • 84861926839 scopus 로고    scopus 로고
    • Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000
    • Liu L, Johnson HL, Cousens S et al. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet 2012; 379:2151–61.
    • (2012) Lancet , vol.379 , pp. 2151-2161
    • Liu, L.1    Johnson, H.L.2    Cousens, S.3
  • 4
    • 77953516842 scopus 로고    scopus 로고
    • Pathophysiology and treatment of septic shock in neonates
    • Wynn JL, Wong HR. Pathophysiology and treatment of septic shock in neonates. Clin Perinatol 2010; 37:439–79.
    • (2010) Clin Perinatol , vol.37 , pp. 439-479
    • Wynn, J.L.1    Wong, H.R.2
  • 5
    • 84897532158 scopus 로고    scopus 로고
    • Protective immunity and defects in the neonatal and elderly immune response to sepsis
    • Gentile LF, Nacionales DC, Lopez MC et al. Protective immunity and defects in the neonatal and elderly immune response to sepsis. J Immunol 2014; 192:3156–65.
    • (2014) J Immunol , vol.192 , pp. 3156-3165
    • Gentile, L.F.1    Nacionales, D.C.2    Lopez, M.C.3
  • 6
    • 73349130456 scopus 로고    scopus 로고
    • Neonatal innate TLR-mediated responses are distinct from those of adults
    • Kollmann TR, Crabtree J, Rein-Weston A et al. Neonatal innate TLR-mediated responses are distinct from those of adults. J Immunol 2009; 183:7150–60.
    • (2009) J Immunol , vol.183 , pp. 7150-7160
    • Kollmann, T.R.1    Crabtree, J.2    Rein-Weston, A.3
  • 7
    • 1542287347 scopus 로고    scopus 로고
    • Neutrophil extracellular traps kill bacteria
    • Brinkmann V, Reichard U, Goosmann C et al. Neutrophil extracellular traps kill bacteria. Science 2004; 303:1532–5.
    • (2004) Science , vol.303 , pp. 1532-1535
    • Brinkmann, V.1    Reichard, U.2    Goosmann, C.3
  • 8
    • 67650638848 scopus 로고    scopus 로고
    • Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates
    • Yost CC, Cody MJ, Harris ES et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood 2009; 113:6419–27.
    • (2009) Blood , vol.113 , pp. 6419-6427
    • Yost, C.C.1    Cody, M.J.2    Harris, E.S.3
  • 9
    • 74049101676 scopus 로고    scopus 로고
    • Delayed but functional neutrophil extracellular trap formation in neonates
    • Marcos V, Nussbaum C, Vitkov L et al. Delayed but functional neutrophil extracellular trap formation in neonates. Blood 2009; 114:4908–11.
    • (2009) Blood , vol.114 , pp. 4908-4911
    • Marcos, V.1    Nussbaum, C.2    Vitkov, L.3
  • 11
    • 0033882622 scopus 로고    scopus 로고
    • Neutrophil production and function in newborn infants
    • Carr R. Neutrophil production and function in newborn infants. Br J Haematol 2000; 110:18–28.
    • (2000) Br J Haematol , vol.110 , pp. 18-28
    • Carr, R.1
  • 12
    • 34247588114 scopus 로고    scopus 로고
    • Innate immunity of the newborn: basic mechanisms and clinical correlates
    • Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol 2007; 7:379–90.
    • (2007) Nat Rev Immunol , vol.7 , pp. 379-390
    • Levy, O.1
  • 13
    • 85018332809 scopus 로고    scopus 로고
    • S100-alarmin-induced innate immune programming protects newborn infants from sepsis
    • Ulas T, Pirr S, Fehlhaber B et al. S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol 2017; 18:622–32.
    • (2017) Nat Immunol , vol.18 , pp. 622-632
    • Ulas, T.1    Pirr, S.2    Fehlhaber, B.3
  • 14
    • 52649156933 scopus 로고    scopus 로고
    • Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists
    • Wynn JL, Scumpia PO, Winfield RD et al. Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood 2008; 112:1750–8.
    • (2008) Blood , vol.112 , pp. 1750-1758
    • Wynn, J.L.1    Scumpia, P.O.2    Winfield, R.D.3
  • 15
    • 7044274793 scopus 로고    scopus 로고
    • Aluminium compounds for use in vaccines
    • Lindblad EB. Aluminium compounds for use in vaccines. Immunol Cell Biol 2004; 82:497–505.
    • (2004) Immunol Cell Biol , vol.82 , pp. 497-505
    • Lindblad, E.B.1
  • 16
    • 51149090409 scopus 로고    scopus 로고
    • Alum adjuvanticity: unraveling a century old mystery
    • De Gregorio E, Tritto E, Rappuoli R. Alum adjuvanticity: unraveling a century old mystery. Eur J Immunol 2008; 38:2068–71.
    • (2008) Eur J Immunol , vol.38 , pp. 2068-2071
    • De Gregorio, E.1    Tritto, E.2    Rappuoli, R.3
  • 17
    • 79953747554 scopus 로고    scopus 로고
    • Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
    • Flach TL, Ng G, Hari A et al. Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med 2011; 17:479–87.
    • (2011) Nat Med , vol.17 , pp. 479-487
    • Flach, T.L.1    Ng, G.2    Hari, A.3
  • 18
    • 84954395099 scopus 로고    scopus 로고
    • IL-1alpha and inflammasome-independent IL-1beta promote neutrophil infiltration following alum vaccination
    • Oleszycka E, Moran HB, Tynan GA et al. IL-1alpha and inflammasome-independent IL-1beta promote neutrophil infiltration following alum vaccination. FEBS J 2016; 283:9–24.
    • (2016) FEBS J , vol.283 , pp. 9-24
    • Oleszycka, E.1    Moran, H.B.2    Tynan, G.A.3
  • 19
    • 36249028582 scopus 로고    scopus 로고
    • Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis
    • Wynn JL, Scumpia PO, Delano MJ et al. Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis. Shock 2007; 28:675–83.
    • (2007) Shock , vol.28 , pp. 675-683
    • Wynn, J.L.1    Scumpia, P.O.2    Delano, M.J.3
  • 20
    • 84929661062 scopus 로고    scopus 로고
    • Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation
    • Gentile LF, Cuenca AL, Cuenca AG et al. Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation. Immunology 2015; 145:300–11.
    • (2015) Immunology , vol.145 , pp. 300-311
    • Gentile, L.F.1    Cuenca, A.L.2    Cuenca, A.G.3
  • 21
    • 33750580090 scopus 로고    scopus 로고
    • Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18
    • Sarkar A, Hall MW, Exline M et al. Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1beta and interleukin-18. Am J Respir Crit Care Med 2006; 174:1003–10.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1003-1010
    • Sarkar, A.1    Hall, M.W.2    Exline, M.3
  • 22
    • 84941694791 scopus 로고    scopus 로고
    • Effects of the antioxidants Trolox, Tiron and Tempol on neutrophil extracellular trap formation
    • Vorobjeva NV, Pinegin BV. Effects of the antioxidants Trolox, Tiron and Tempol on neutrophil extracellular trap formation. Immunobiology 2016; 221:208–19.
    • (2016) Immunobiology , vol.221 , pp. 208-219
    • Vorobjeva, N.V.1    Pinegin, B.V.2
  • 23
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008; 453:1122–6.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 24
    • 84875169169 scopus 로고    scopus 로고
    • Alarmins, inflammasomes and immunity
    • Said-Sadier N, Ojcius DM. Alarmins, inflammasomes and immunity. Biomed J 2012; 35:437–49.
    • (2012) Biomed J , vol.35 , pp. 437-449
    • Said-Sadier, N.1    Ojcius, D.M.2
  • 25
    • 38849135780 scopus 로고    scopus 로고
    • CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis
    • Nolan A, Weiden M, Kelly A et al. CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis. Am J Resp Crit Care Med 2008; 177:301–8.
    • (2008) Am J Resp Crit Care Med , vol.177 , pp. 301-308
    • Nolan, A.1    Weiden, M.2    Kelly, A.3
  • 26
    • 84926464652 scopus 로고    scopus 로고
    • Delayed emergency myelopoiesis following polymicrobial sepsis in neonates
    • Cuenca AG, Cuenca AL, Gentile LF et al. Delayed emergency myelopoiesis following polymicrobial sepsis in neonates. Innate Immun 2015; 21:386–91.
    • (2015) Innate Immun , vol.21 , pp. 386-391
    • Cuenca, A.G.1    Cuenca, A.L.2    Gentile, L.F.3
  • 27
    • 33644985564 scopus 로고    scopus 로고
    • Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase- 1
    • Sutterwala FS, Ogura Y, Szczepanik M et al. Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase- 1. Immunity 2006; 24:317–27.
    • (2006) Immunity , vol.24 , pp. 317-327
    • Sutterwala, F.S.1    Ogura, Y.2    Szczepanik, M.3
  • 28
    • 84957991591 scopus 로고    scopus 로고
    • The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists
    • Chen KW, Bezbradica JS, Groß CJ et al. The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists. Eur J Immunol 2016; 46:1004–10.
    • (2016) Eur J Immunol , vol.46 , pp. 1004-1010
    • Chen, K.W.1    Bezbradica, J.S.2    Groß, C.J.3
  • 29
    • 84876156655 scopus 로고    scopus 로고
    • Particulate adjuvant and innate immunity: past achievements, present findings, and future prospects
    • Kuroda E, Coban C, Ishii KJ. Particulate adjuvant and innate immunity: past achievements, present findings, and future prospects. Int Rev Immunol 2013; 32:209–20.
    • (2013) Int Rev Immunol , vol.32 , pp. 209-220
    • Kuroda, E.1    Coban, C.2    Ishii, K.J.3
  • 30
    • 42249088234 scopus 로고    scopus 로고
    • Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
    • Kool M, Soullie T, van Nimwegen M et al. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med 2008; 205:869–82.
    • (2008) J Exp Med , vol.205 , pp. 869-882
    • Kool, M.1    Soullie, T.2    van Nimwegen, M.3
  • 31
    • 79961167250 scopus 로고    scopus 로고
    • DNA released from dying host cells mediates aluminum adjuvant activity
    • Marichal T, Ohata K, Bedoret D et al. DNA released from dying host cells mediates aluminum adjuvant activity. Nat Med 2011; 17:996–1002.
    • (2011) Nat Med , vol.17 , pp. 996-1002
    • Marichal, T.1    Ohata, K.2    Bedoret, D.3
  • 32
    • 84878245034 scopus 로고    scopus 로고
    • Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
    • Sokolovska A, Becker CE, Ip WK et al. Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function. Nat Immunol 2013; 14:543–53.
    • (2013) Nat Immunol , vol.14 , pp. 543-553
    • Sokolovska, A.1    Becker, C.E.2    Ip, W.K.3
  • 33
    • 70449713915 scopus 로고    scopus 로고
    • Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity
    • McKee AS, Munks MW, MacLeod MK et al. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol 2009; 183:4403–14.
    • (2009) J Immunol , vol.183 , pp. 4403-4414
    • McKee, A.S.1    Munks, M.W.2    MacLeod, M.K.3
  • 34
    • 84971232127 scopus 로고    scopus 로고
    • Adjuvant-induced human monocyte secretome profiles reveal adjuvant- and age-specific protein signatures
    • Oh DY, Dowling DJ, Ahmed S et al. Adjuvant-induced human monocyte secretome profiles reveal adjuvant- and age-specific protein signatures. Mol Cell Proteomics 2016; 15:1877–94.
    • (2016) Mol Cell Proteomics , vol.15 , pp. 1877-1894
    • Oh, D.Y.1    Dowling, D.J.2    Ahmed, S.3
  • 35
    • 56149119563 scopus 로고    scopus 로고
    • Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
    • Kool M, Petrilli V, De Smedt T et al. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008; 181:3755–9.
    • (2008) J Immunol , vol.181 , pp. 3755-3759
    • Kool, M.1    Petrilli, V.2    De Smedt, T.3
  • 36
    • 0023580206 scopus 로고
    • Abnormal stimulated adherence of neonatal granulocytes: impaired induction of surface Mac-1 by chemotactic factors or secretagogues
    • Anderson DC, Freeman KL, Heerdt B, Hughes BJ, Jack RM, Smith CW. Abnormal stimulated adherence of neonatal granulocytes: impaired induction of surface Mac-1 by chemotactic factors or secretagogues. Blood 1987; 70:740–50.
    • (1987) Blood , vol.70 , pp. 740-750
    • Anderson, D.C.1    Freeman, K.L.2    Heerdt, B.3    Hughes, B.J.4    Jack, R.M.5    Smith, C.W.6
  • 37
    • 84923373400 scopus 로고    scopus 로고
    • Diagnostic value of elevated CXCR4 and CXCL12 in neonatal sepsis
    • Tunc T, Cekmez F, Cetinkaya M et al. Diagnostic value of elevated CXCR4 and CXCL12 in neonatal sepsis. J Matern Fetal Neonatal Med 2015; 28:356–61.
    • (2015) J Matern Fetal Neonatal Med , vol.28 , pp. 356-361
    • Tunc, T.1    Cekmez, F.2    Cetinkaya, M.3
  • 38
    • 0347285361 scopus 로고    scopus 로고
    • Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression
    • Ueda Y, Yang K, Foster SJ, Kondo M, Kelsoe G. Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression. J Exp Med 2004; 199:47–58.
    • (2004) J Exp Med , vol.199 , pp. 47-58
    • Ueda, Y.1    Yang, K.2    Foster, S.J.3    Kondo, M.4    Kelsoe, G.5
  • 39
    • 0034684650 scopus 로고    scopus 로고
    • Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice
    • Gartner F, Alt FW, Monroe RJ, Seidl KJ. Antigen-independent appearance of recombination activating gene (RAG)-positive bone marrow B cells in the spleens of immunized mice. J Exp Med 2000; 192:1745–54.
    • (2000) J Exp Med , vol.192 , pp. 1745-1754
    • Gartner, F.1    Alt, F.W.2    Monroe, R.J.3    Seidl, K.J.4
  • 40
    • 0021720104 scopus 로고
    • Neutropenia in high-risk neonates
    • Engle WD, Rosenfeld CR. Neutropenia in high-risk neonates. J Pediatr 1984; 105:982–6.
    • (1984) J Pediatr , vol.105 , pp. 982-986
    • Engle, W.D.1    Rosenfeld, C.R.2


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