-
1
-
-
77950362382
-
The inflammasomes
-
Schroder, K. and Tschopp, J., The inflammasomes. Cell 2010. 140: 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
2
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo, R., Kuffa, P., Martinez-Colon, G., Smith, B. L., Rajendiran, T. M. and Nunez, G., K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 2013. 38: 1142-1153.
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
3
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A. et al., Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 2008. 9: 847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
-
4
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz, C. M., Rinna, A., Forman, H. J., Ventura, A. L., Persechini, P. M. and Ojcius, D. M., ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 2007. 282: 2871-2879.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
5
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami, T., Ockinger, J., Yu, J., Byles, V., McColl, A., Hofer, A. M. and Horng, T., Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc.Natl. Acad. Sci. U S A 2012. 109: 11282-11287.
-
(2012)
Proc.Natl. Acad. Sci. U S A
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
6
-
-
84870824875
-
Neutrophil-derived IL-1beta is sufficient for abscess formation in immunity against Staphylococcus aureus in mice
-
Cho, J. S., Guo, Y., Ramos, R. I., Hebroni, F., Plaisier, S. B., Xuan, C., Granick, J. L. et al., Neutrophil-derived IL-1beta is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. PLoS Pathog. 2012. 8: e1003047-31003047.
-
(2012)
PLoS Pathog
, vol.8
, pp. e1003047-31003047
-
-
Cho, J.S.1
Guo, Y.2
Ramos, R.I.3
Hebroni, F.4
Plaisier, S.B.5
Xuan, C.6
Granick, J.L.7
-
7
-
-
84922553500
-
Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux
-
Karmakar, M., Katsnelson, M., Malak, H. A., Greene, N. G., Howell, S. J., Hise, A. G., Camilli, A. et al., Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. J. Immunol. 2015. 194: 1763-1775.
-
(2015)
J. Immunol.
, vol.194
, pp. 1763-1775
-
-
Karmakar, M.1
Katsnelson, M.2
Malak, H.A.3
Greene, N.G.4
Howell, S.J.5
Hise, A.G.6
Camilli, A.7
-
8
-
-
84904792729
-
The neutrophil NLRC4 inflammasome selectively promotes IL-1beta maturation without pyroptosis during acute Salmonella challenge
-
Chen, K. W., Gross, C. J., Sotomayor, F. V., Stacey, K. J., Tschopp, J., Sweet, M. J. and Schroder, K., The neutrophil NLRC4 inflammasome selectively promotes IL-1beta maturation without pyroptosis during acute Salmonella challenge. Cell Rep. 2014. 8: 570-582.
-
(2014)
Cell Rep.
, vol.8
, pp. 570-582
-
-
Chen, K.W.1
Gross, C.J.2
Sotomayor, F.V.3
Stacey, K.J.4
Tschopp, J.5
Sweet, M.J.6
Schroder, K.7
-
9
-
-
84859492693
-
The NLRP3/ASC/Caspase-1 axis regulates IL-1beta processing in neutrophils
-
Mankan, A. K., Dau, T., Jenne, D. and Hornung, V., The NLRP3/ASC/Caspase-1 axis regulates IL-1beta processing in neutrophils. Eur. J. Immunol. 2012. 42: 710-715.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 710-715
-
-
Mankan, A.K.1
Dau, T.2
Jenne, D.3
Hornung, V.4
-
10
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind, F. G., Horvath, G., Stutz, A., Alnemri, E. S., MacDonald, K., Speert, D., Fernandes-Alnemri, T. et al., Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J. Immunol. 2009. 183: 787-791.
-
(2009)
J. Immunol.
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
-
11
-
-
84869088114
-
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
-
Schroder, K., Sagulenko, V., Zamoshnikova, A., Richards, A. A., Cridland, J. A., Irvine, K. M., Stacey, K. J. et al., Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology 2012. 217: 1325-1329.
-
(2012)
Immunobiology
, vol.217
, pp. 1325-1329
-
-
Schroder, K.1
Sagulenko, V.2
Zamoshnikova, A.3
Richards, A.A.4
Cridland, J.A.5
Irvine, K.M.6
Stacey, K.J.7
-
12
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti, T. D., Ozoren, N., Body-Malapel, M., Amer, A., Park, J. H., Franchi, L., Whitfield, J. et al., Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006. 440: 233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfield, J.7
-
13
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P. et al., Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006. 440: 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
-
14
-
-
84858761335
-
Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1
-
Gross, O., Yazdi, A. S., Thomas, C. J., Masin, M., Heinz, L. X., Guarda, G., Quadroni, M. et al., Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1. Immunity 2012. 36: 388-400.
-
(2012)
Immunity
, vol.36
, pp. 388-400
-
-
Gross, O.1
Yazdi, A.S.2
Thomas, C.J.3
Masin, M.4
Heinz, L.X.5
Guarda, G.6
Quadroni, M.7
-
15
-
-
84896733932
-
Localization and functionality of the inflammasome in neutrophils
-
Bakele, M., Joos, M., Burdi, S., Allgaier, N., Poschel, S., Fehrenbacher, B., Schaller, M.et al., Localization and functionality of the inflammasome in neutrophils. J. Biol. Chem. 2014. 289: 5320-5329.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 5320-5329
-
-
Bakele, M.1
Joos, M.2
Burdi, S.3
Allgaier, N.4
Poschel, S.5
Fehrenbacher, B.6
Schaller, M.7
-
16
-
-
34247219224
-
(S)-1-((S)-2-([1-(4-amino-3-chloro-phenyl)-methanoyl]-amino)-3,3-dimethyl-butanoy l)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18
-
Wannamaker, W., Davies, R., Namchuk, M., Pollard, J., Ford, P., Ku, G., Decker, C.et al., (S)-1-((S)-2-([1-(4-amino-3-chloro-phenyl)-methanoyl]-amino)-3, 3-dimethyl-butanoy l)-pyrrolidine-2-carboxylic acid ((2R, 3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18. J. Pharmacol. Exp. Ther. 2007. 321: 509-516.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 509-516
-
-
Wannamaker, W.1
Davies, R.2
Namchuk, M.3
Pollard, J.4
Ford, P.5
Ku, G.6
Decker, C.7
-
17
-
-
64049084303
-
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages
-
Netea, M. G., Nold-Petry, C. A., Nold, M. F., Joosten, L. A., Opitz, B., van der Meer, J. H., van de Veerdonk, F. L. et al., Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood 2009. 113: 2324-2335.
-
(2009)
Blood
, vol.113
, pp. 2324-2335
-
-
Netea, M.G.1
Nold-Petry, C.A.2
Nold, M.F.3
Joosten, L.A.4
Opitz, B.5
van der Meer, J.H.6
van de Veerdonk, F.L.7
-
18
-
-
84874280285
-
Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells
-
Schorn, C., Janko, C., Latzko, M., Chaurio, R., Schett, G. and Herrmann, M., Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells. Front. Immunol. 2012. 3: 277.
-
(2012)
Front. Immunol.
, vol.3
, pp. 277
-
-
Schorn, C.1
Janko, C.2
Latzko, M.3
Chaurio, R.4
Schett, G.5
Herrmann, M.6
-
19
-
-
84880676381
-
Diverse novel functions of neutrophils in immunity, inflammation, and beyond
-
Mocsai, A., Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J. Exp. Med. 2013. 210: 1283-1299.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1283-1299
-
-
Mocsai, A.1
-
20
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth, S. C., Colegio, O. R., O'Connor, W., Sutterwala, F. S. and Flavell, R. A., Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008. 453: 1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
21
-
-
84880788557
-
Pattern recognition receptor function in neutrophils
-
Thomas, C. J. and Schroder, K., Pattern recognition receptor function in neutrophils. Trends Immunol. 2013. 34: 317-328.
-
(2013)
Trends Immunol.
, vol.34
, pp. 317-328
-
-
Thomas, C.J.1
Schroder, K.2
-
22
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida, K., Lippke, J. A., Ku, G., Harding, M. W., Livingston, D. J., Su, M. S. and Flavell, R. A., Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995. 267: 2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
23
-
-
84859993180
-
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
-
Schroder, K., Irvine, K. M., Taylor, M. S., Bokil, N. J., Le Cao, K. A., Masterman, K. A., Labzin, L. I. et al., Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proc. Natl. Acad. Sci. U S A 2012. 109: E944-E953.
-
(2012)
Proc. Natl. Acad. Sci. U S A
, vol.109
, pp. E944-E953
-
-
Schroder, K.1
Irvine, K.M.2
Taylor, M.S.3
Bokil, N.J.4
Le Cao, K.A.5
Masterman, K.A.6
Labzin, L.I.7
-
24
-
-
84856271953
-
Measuring the inflammasome
-
Gross, O., Measuring the inflammasome. Methods Mol. Biol. 2012. 844: 199-222.
-
(2012)
Methods Mol. Biol.
, vol.844
, pp. 199-222
-
-
Gross, O.1
-
25
-
-
32944465559
-
DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps
-
Buchanan, J. T., Simpson, A. J., Aziz, R. K., Liu, G. Y., Kristian, S. A., Kotb, M., Feramisco, J. et al., DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr. Biol. 2006. 16: 396-400.
-
(2006)
Curr. Biol.
, vol.16
, pp. 396-400
-
-
Buchanan, J.T.1
Simpson, A.J.2
Aziz, R.K.3
Liu, G.Y.4
Kristian, S.A.5
Kotb, M.6
Feramisco, J.7
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