Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation

Immunology

Volumn 145, Issue 2, 2015, Pages 300-311

  Gentile, Lori F ^a   Cuenca, Angela L ^a   Cuenca, Alex G ^a   Nacionales, Dina C ^a   Ungaro, Ricardo ^a   Efron, Philip A ^a   Moldawer, Lyle L ^a   Larson, Shawn D ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Caspase 1 11; Emergency myelopoiesis; Inflammation; Mouse; Neonates

Indexed keywords

CASPASE 11; COLONY STIMULATING FACTOR 1; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INFLAMMASOME; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CASP11 PROTEIN, MOUSE; CASPASE; CIAS1 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BONE MARROW; COMPARATIVE STUDY; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; HEMATOPOIETIC STEM CELL; INFLAMMATION; INNATE IMMUNITY; MALE; MOUSE; MYELOPOIESIS; NEWBORN; NEWBORN MORTALITY; NEWBORN SEPSIS; NONHUMAN; PERITONEUM; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; STEM CELL EXPANSION; ANIMAL; DISEASE MODEL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; NEUTROPHIL; PATHOLOGY; SEPSIS;

ANIMALS; ANIMALS, NEWBORN; CARRIER PROTEINS; CASPASE 1; CASPASES; DISEASE MODELS, ANIMAL; HEMATOPOIETIC STEM CELLS; IMMUNITY, INNATE; INFLAMMASOMES; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MYELOPOIESIS; NEUTROPHILS; PHAGOCYTOSIS; SEPSIS;

EID: 84929661062     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12450     Document Type: Article

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