Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection

Genome Biology

Volumn 18, Issue 1, 2017, Pages

  Wyler, Emanuel ^a   Menegatti, Jennifer ^b   Franke, Vedran ^a   Kocks, Christine ^a   Boltengagen, Anastasiya ^a   Hennig, Thomas ^c   Theil, Kathrin ^a   Rutkowski, Andrzej ^d,e   Ferrai, Carmelo ^a   Baer, Laura ^b   Kermas, Lisa ^a   Friedel, Caroline ^f   Rajewsky, Nikolaus ^a   Akalin, Altuna ^a   Dölken, Lars ^c   Grässer, Friedrich ^b   Landthaler, Markus ^a,g  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ASTRAZENECA   (United Kingdom)

^f UNIVERSITY OF MUNICH   (Germany)

^g HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Antisense; BBC3; Herpes; ICP4; LncRNA; NFKB; Transcription; Virus

Indexed keywords

COMPLEMENTARY RNA; HISTONE; PROTEIN ICP4; PUMA PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BBC3 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; ONCOPROTEIN; VIRAL PROTEIN;

APOPTOSIS; ARTICLE; BBC3 GENE; DOWN REGULATION; GENE LOCUS; GENE OVEREXPRESSION; GENE SILENCING; GENETIC SUSCEPTIBILITY; HERPES SIMPLEX; HOST CELL; HUMAN; HUMAN ALPHAHERPESVIRUS 1; NONHUMAN; PROMOTER REGION; TRANSCRIPTION INITIATION SITE; VARICELLA ZOSTER VIRUS; VIRUS GENE; VIRUS GENOME; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HELA CELL LINE; HISTONE CODE; HOST PATHOGEN INTERACTION; HUMAN GENOME; METABOLISM; MONOCYTE; PHYSIOLOGY; REPRODUCIBILITY; SEQUENCE ANALYSIS; VIROLOGY;

APOPTOSIS REGULATORY PROTEINS; GENE EXPRESSION REGULATION, VIRAL; GENOME, HUMAN; HELA CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HISTONE CODE; HOST-PATHOGEN INTERACTIONS; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; NF-KAPPA B; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; REPRODUCIBILITY OF RESULTS; RNA, ANTISENSE; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 85033407041     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-017-1329-5     Document Type: Article

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