-
1
-
-
84991325493
-
HDACs and HDAC inhibitors in cancer development and therapy
-
Li Y, Seto E. HDACs and HDAC inhibitors in cancer development and therapy. Cold Spring Harb Perspect Med. 2016;6:a026831.
-
(2016)
Cold Spring Harb Perspect Med.
, vol.6
-
-
Li, Y.1
Seto, E.2
-
3
-
-
33646354640
-
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
-
Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Boix-Chornet M, Caballero R, Alaminos M, Setien F, Paz MF. A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat Genet. 2006;38:566-9.
-
(2006)
Nat Genet
, vol.38
, pp. 566-569
-
-
Ropero, S.1
Fraga, M.F.2
Ballestar, E.3
Hamelin, R.4
Yamamoto, H.5
Boix-Chornet, M.6
Caballero, R.7
Alaminos, M.8
Setien, F.9
Paz, M.F.10
-
4
-
-
4544322261
-
Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients
-
Osada H, Tatematsu Y, Saito H, Yatabe Y, Mitsudomi T, Takahashi T. Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients. Int J Cancer. 2004;112:26-32.
-
(2004)
Int J Cancer
, vol.112
, pp. 26-32
-
-
Osada, H.1
Tatematsu, Y.2
Saito, H.3
Yatabe, Y.4
Mitsudomi, T.5
Takahashi, T.6
-
5
-
-
84911496124
-
Decreased expression of histone deacetylase 10 predicts poor prognosis of gastric cancer patients
-
Jin Z, Jiang W, Jiao F, Guo Z, Hu H, Wang L, Wang L. Decreased expression of histone deacetylase 10 predicts poor prognosis of gastric cancer patients. Int J Clin Exp Pathol. 2014;7:5872-9.
-
(2014)
Int J Clin Exp Pathol
, vol.7
, pp. 5872-5879
-
-
Jin, Z.1
Jiang, W.2
Jiao, F.3
Guo, Z.4
Hu, H.5
Wang, L.6
Wang, L.7
-
6
-
-
35148885660
-
Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice
-
Zimmermann S, Kiefer F, Prudenziati M, Spiller C, Hansen J, Floss T, Wurst W, Minucci S, Göttlicher M. Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. Cancer Res. 2007;67:9047-54.
-
(2007)
Cancer Res
, vol.67
, pp. 9047-9054
-
-
Zimmermann, S.1
Kiefer, F.2
Prudenziati, M.3
Spiller, C.4
Hansen, J.5
Floss, T.6
Wurst, W.7
Minucci, S.8
Göttlicher, M.9
-
7
-
-
78249276172
-
Hdac3 is essential for the maintenance of chromatin structure and genome stability
-
Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan J-l, Bonine-Summers AR. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 2010;18:436-47.
-
(2010)
Cancer Cell
, vol.18
, pp. 436-447
-
-
Bhaskara, S.1
Knutson, S.K.2
Jiang, G.3
Chandrasekharan, M.B.4
Wilson, A.J.5
Zheng, S.6
Yenamandra, A.7
Locke, K.8
Yuan, J.-L.9
Bonine-Summers, A.R.10
-
8
-
-
84879341188
-
A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance
-
Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S. A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. Blood. 2013;121:3459-68.
-
(2013)
Blood
, vol.121
, pp. 3459-3468
-
-
Santoro, F.1
Botrugno, O.A.2
Dal Zuffo, R.3
Pallavicini, I.4
Matthews, G.M.5
Cluse, L.6
Barozzi, I.7
Senese, S.8
Fornasari, L.9
Moretti, S.10
-
9
-
-
33746228132
-
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10
-
Chang S, Young BD, Li S, Qi X, Richardson JA, Olson EN. Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell. 2006;126:321-34.
-
(2006)
Cell
, vol.126
, pp. 321-334
-
-
Chang, S.1
Young, B.D.2
Li, S.3
Qi, X.4
Richardson, J.A.5
Olson, E.N.6
-
10
-
-
48149115853
-
High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas
-
Ouaissi M, Sielezneff I, Silvestre R, Sastre B, Bernard JP, Lafontaine JS, Payan MJ, Dahan L, Pirro N, Seitz JF, et al. High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Ann Surg Oncol. 2008;15:2318-28.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 2318-2328
-
-
Ouaissi, M.1
Sielezneff, I.2
Silvestre, R.3
Sastre, B.4
Bernard, J.P.5
Lafontaine, J.S.6
Payan, M.J.7
Dahan, L.8
Pirro, N.9
Seitz, J.F.10
-
11
-
-
84989827185
-
Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer
-
Witt AE, Lee CW, Lee TI, Azzam DJ, Wang B, Caslini C, Petrocca F, Grosso J, Jones M, Cohick EB, et al. Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer. Oncogene. 2016;36:1707-20.
-
(2016)
Oncogene.
, vol.36
, pp. 1707-1720
-
-
Witt, A.E.1
Lee, C.W.2
Lee, T.I.3
Azzam, D.J.4
Wang, B.5
Caslini, C.6
Petrocca, F.7
Grosso, J.8
Jones, M.9
Cohick, E.B.10
-
12
-
-
77956309330
-
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia
-
Moreno DA, Scrideli CA, Cortez MA, de Paula Queiroz R, Valera ET, da Silva Silveira V, Yunes JA, Brandalise SR, Tone LG. Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia. Br J Haematol. 2010;150:665-73.
-
(2010)
Br J Haematol
, vol.150
, pp. 665-673
-
-
Moreno, D.A.1
Scrideli, C.A.2
Cortez, M.A.3
de Paula Queiroz, R.4
Valera, E.T.5
da Silva Silveira, V.6
Yunes, J.A.7
Brandalise, S.R.8
Tone, L.G.9
-
13
-
-
84927583783
-
The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma
-
Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam A, Vega-García N, Malatesta R, Camós M, Gómez A. The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma. Cell Death Dis. 2015;6:e1635.
-
(2015)
Cell Death Dis
, vol.6
-
-
Barneda-Zahonero, B.1
Collazo, O.2
Azagra, A.3
Fernández-Duran, I.4
Serra-Musach, J.5
Islam, A.6
Vega-García, N.7
Malatesta, R.8
Camós, M.9
Gómez, A.10
-
14
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
Yuan Z-l, Guan Y-j, Chatterjee D, Chin YE. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science. 2005;307:269-73.
-
(2005)
Science
, vol.307
, pp. 269-273
-
-
Yuan, Z.-L.1
Guan, Y.-J.2
Chatterjee, D.3
Chin, Y.E.4
-
15
-
-
64049109876
-
STAT3 inhibition of gluconeogenesis is downregulated by SirT1
-
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. STAT3 inhibition of gluconeogenesis is downregulated by SirT1. Nat Cell Biol. 2009;11:492-500.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 492-500
-
-
Nie, Y.1
Erion, D.M.2
Yuan, Z.3
Dietrich, M.4
Shulman, G.I.5
Horvath, T.L.6
Gao, Q.7
-
17
-
-
84871862427
-
STAT3 negatively regulates thyroid tumorigenesis
-
Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simoes M, Lima J, Maximo V, Soares P, Lyden D, Bromberg JF. STAT3 negatively regulates thyroid tumorigenesis. Proc Natl Acad Sci U S A. 2012;109:E2361-70.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E2361-E2370
-
-
Couto, J.P.1
Daly, L.2
Almeida, A.3
Knauf, J.A.4
Fagin, J.A.5
Sobrinho-Simoes, M.6
Lima, J.7
Maximo, V.8
Soares, P.9
Lyden, D.10
Bromberg, J.F.11
-
18
-
-
84863961382
-
Basal STAT3 activities are negatively correlated with tumor size in papillary thyroid carcinomas
-
Kim WG, Choi HJ, Kim WB, Kim EY, Yim JH, Kim TY, Gong G, Kim SY, Chung N, Shong YK. Basal STAT3 activities are negatively correlated with tumor size in papillary thyroid carcinomas. J Endocrinol Investig. 2012;35:413-8.
-
(2012)
J Endocrinol Investig
, vol.35
, pp. 413-418
-
-
Kim, W.G.1
Choi, H.J.2
Kim, W.B.3
Kim, E.Y.4
Yim, J.H.5
Kim, T.Y.6
Gong, G.7
Kim, S.Y.8
Chung, N.9
Shong, Y.K.10
-
19
-
-
84868192377
-
Phosphorylation of signal transducer and activator of transcription 3 in soft tissue leiomyosarcoma is associated with a better prognosis
-
Setsu N, Kohashi K, Endo M, Yamamoto H, Tamiya S, Takahashi Y, Yamada Y, Ishii T, Matsuda S, Yokoyama R. Phosphorylation of signal transducer and activator of transcription 3 in soft tissue leiomyosarcoma is associated with a better prognosis. Int J Cancer. 2013;132:109-15.
-
(2013)
Int J Cancer
, vol.132
, pp. 109-115
-
-
Setsu, N.1
Kohashi, K.2
Endo, M.3
Yamamoto, H.4
Tamiya, S.5
Takahashi, Y.6
Yamada, Y.7
Ishii, T.8
Matsuda, S.9
Yokoyama, R.10
-
20
-
-
84880271158
-
Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma
-
Gordziel C, Bratsch J, Moriggl R, Knosel T, Friedrich K. Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma. Br J Cancer. 2013;109:138-46.
-
(2013)
Br J Cancer
, vol.109
, pp. 138-146
-
-
Gordziel, C.1
Bratsch, J.2
Moriggl, R.3
Knosel, T.4
Friedrich, K.5
-
21
-
-
0041620205
-
Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis
-
Hsiao JR, Jin YT, Tsai ST, Shiau AL, Wu CL, Su WC. Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis. Br J Cancer. 2003;89:344-9.
-
(2003)
Br J Cancer
, vol.89
, pp. 344-349
-
-
Hsiao, J.R.1
Jin, Y.T.2
Tsai, S.T.3
Shiau, A.L.4
Wu, C.L.5
Su, W.C.6
-
22
-
-
77249098774
-
Stat3 is a negative regulator of intestinal tumor progression in Apc(min) mice
-
Musteanu M, Blaas L, Mair M, Schlederer M, Bilban M, Tauber S, Esterbauer H, Mueller M, Casanova E, Kenner L, et al. Stat3 is a negative regulator of intestinal tumor progression in Apc(min) mice. Gastroenterology. 2010;138:1003-11. e1001-1005
-
(2010)
Gastroenterology
, vol.138
, pp. 1003-1011
-
-
Musteanu, M.1
Blaas, L.2
Mair, M.3
Schlederer, M.4
Bilban, M.5
Tauber, S.6
Esterbauer, H.7
Mueller, M.8
Casanova, E.9
Kenner, L.10
-
23
-
-
84924185168
-
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis
-
Grabner B, Schramek D, Mueller KM, Moll HP, Svinka J, Hoffmann T, Bauer E, Blaas L, Hruschka N, Zboray K, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285.
-
(2015)
Nat Commun
, vol.6
, pp. 6285
-
-
Grabner, B.1
Schramek, D.2
Mueller, K.M.3
Moll, H.P.4
Svinka, J.5
Hoffmann, T.6
Bauer, E.7
Blaas, L.8
Hruschka, N.9
Zboray, K.10
-
24
-
-
39449093328
-
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
-
de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008;22:449-62.
-
(2008)
Genes Dev
, vol.22
, pp. 449-462
-
-
de la Iglesia, N.1
Konopka, G.2
Puram, S.V.3
Chan, J.A.4
Bachoo, R.M.5
You, M.J.6
Levy, D.E.7
Depinho, R.A.8
Bonni, A.9
-
25
-
-
34548785120
-
Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung
-
Li Y, Du H, Qin Y, Roberts J, Cummings OW, Yan C. Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung. Cancer Res. 2007;67:8494-503.
-
(2007)
Cancer Res
, vol.67
, pp. 8494-8503
-
-
Li, Y.1
Du, H.2
Qin, Y.3
Roberts, J.4
Cummings, O.W.5
Yan, C.6
-
26
-
-
84555202760
-
Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma
-
Jiang R, Jin Z, Liu Z, Sun L, Wang L, Li K. Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma. Mol Diagn Ther. 2011;15:347-52.
-
(2011)
Mol Diagn Ther
, vol.15
, pp. 347-352
-
-
Jiang, R.1
Jin, Z.2
Liu, Z.3
Sun, L.4
Wang, L.5
Li, K.6
-
27
-
-
76749086953
-
Age-and sex-specific genomic profiles in non-small cell lung cancer
-
Mostertz W, Stevenson M, Acharya C, Chan I, Walters K, Lamlertthon W, Barry W, Crawford J, Nevins J, Potti A. Age-and sex-specific genomic profiles in non-small cell lung cancer. JAMA. 2010;303:535-43.
-
(2010)
JAMA
, vol.303
, pp. 535-543
-
-
Mostertz, W.1
Stevenson, M.2
Acharya, C.3
Chan, I.4
Walters, K.5
Lamlertthon, W.6
Barry, W.7
Crawford, J.8
Nevins, J.9
Potti, A.10
-
28
-
-
84937522140
-
Differential roles of STAT3 in the initiation and growth of lung cancer
-
Zhou J, Qu Z, Yan S, Sun F, Whitsett JA, Shapiro SD, Xiao G. Differential roles of STAT3 in the initiation and growth of lung cancer. Oncogene. 2015;34:3804.
-
(2015)
Oncogene
, vol.34
, pp. 3804
-
-
Zhou, J.1
Qu, Z.2
Yan, S.3
Sun, F.4
Whitsett, J.A.5
Shapiro, S.D.6
Xiao, G.7
-
29
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev. 2001;15:3243-8.
-
(2001)
Genes Dev
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
Bronson, R.T.4
Crowley, D.5
Montoya, R.6
Jacks, T.7
Tuveson, D.A.8
-
30
-
-
68149157175
-
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
-
DuPage M, Dooley AL, Jacks T. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc. 2009;4:1064-72.
-
(2009)
Nat Protoc
, vol.4
, pp. 1064-1072
-
-
DuPage, M.1
Dooley, A.L.2
Jacks, T.3
-
31
-
-
84951809536
-
Mammalian sterile 20-like kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the function of regulatory T cells by modulating Foxp3 Acetylation
-
Li J, Du X, Shi H, Deng K, Chi H, Tao W. Mammalian sterile 20-like kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the function of regulatory T cells by modulating Foxp3 Acetylation. J Biol Chem. 2015;290:30762-70.
-
(2015)
J Biol Chem
, vol.290
, pp. 30762-30770
-
-
Li, J.1
Du, X.2
Shi, H.3
Deng, K.4
Chi, H.5
Tao, W.6
-
32
-
-
0028037530
-
A simple and efficient method for purification of infectious recombinant adenovirus
-
Kanegae Y, Makimura M, Saito I. A simple and efficient method for purification of infectious recombinant adenovirus. Jpn J Med Sci Biol. 1994;47:157-66.
-
(1994)
Jpn J Med Sci Biol
, vol.47
, pp. 157-166
-
-
Kanegae, Y.1
Makimura, M.2
Saito, I.3
-
33
-
-
64749107970
-
Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors
-
Kutner RH, Zhang X-Y, Reiser J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat Protoc. 2009;4:495-505.
-
(2009)
Nat Protoc
, vol.4
, pp. 495-505
-
-
Kutner, R.H.1
Zhang, X.-Y.2
Reiser, J.3
-
34
-
-
0041302154
-
Lats2, a putative tumor suppressor, inhibits G1/S transition
-
Li Y, Pei J, Xia H, Ke H, Wang H, Tao W. Lats2, a putative tumor suppressor, inhibits G1/S transition. Oncogene. 2003;22:4398-405.
-
(2003)
Oncogene
, vol.22
, pp. 4398-4405
-
-
Li, Y.1
Pei, J.2
Xia, H.3
Ke, H.4
Wang, H.5
Tao, W.6
-
35
-
-
84907990586
-
Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages
-
Hsu DS-S, Wang H-J, Tai S-K, Chou C-H, Hsieh C-H, Chiu P-H, Chen N-J, Yang M-H. Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages. Cancer Cell. 2014;26:534-48.
-
(2014)
Cancer Cell
, vol.26
, pp. 534-548
-
-
Hsu, D.-S.1
Wang, H.-J.2
Tai, S.-K.3
Chou, C.-H.4
Hsieh, C.-H.5
Chiu, P.-H.6
Chen, N.-J.7
Yang, M.-H.8
-
36
-
-
77951276571
-
Histone deacetylase 7 controls endothelial cell growth through modulation of β-catenin
-
Margariti A, Zampetaki A, Xiao Q, Zhou B, Karamariti E, Martin D, Yin X, Mayr M, Li H, Zhang Z. Histone deacetylase 7 controls endothelial cell growth through modulation of β-catenin. Circ Res. 2010;106:1202-11.
-
(2010)
Circ Res
, vol.106
, pp. 1202-1211
-
-
Margariti, A.1
Zampetaki, A.2
Xiao, Q.3
Zhou, B.4
Karamariti, E.5
Martin, D.6
Yin, X.7
Mayr, M.8
Li, H.9
Zhang, Z.10
-
37
-
-
45549101405
-
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7
-
Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN. Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proc Natl Acad Sci U S A. 2008;105:7738-43.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7738-7743
-
-
Wang, S.1
Li, X.2
Parra, M.3
Verdin, E.4
Bassel-Duby, R.5
Olson, E.N.6
-
38
-
-
79955761350
-
The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc
-
Zhu C, Chen Q, Xie Z, Ai J, Tong L, Ding J, Geng M. The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc. J Mol Med. 2011;89:279-89.
-
(2011)
J Mol Med
, vol.89
, pp. 279-289
-
-
Zhu, C.1
Chen, Q.2
Xie, Z.3
Ai, J.4
Tong, L.5
Ding, J.6
Geng, M.7
-
39
-
-
79551532277
-
Neuroprotection by histone deacetylase-7 (HDAC7) occurs by inhibition of c-jun expression through a deacetylase-independent mechanism
-
Ma C, D'Mello SR. Neuroprotection by histone deacetylase-7 (HDAC7) occurs by inhibition of c-jun expression through a deacetylase-independent mechanism. J Biol Chem. 2011;286:4819-28.
-
(2011)
J Biol Chem
, vol.286
, pp. 4819-4828
-
-
Ma, C.1
D'Mello, S.R.2
-
40
-
-
0037728615
-
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis
-
Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity. 2003;18:687-98.
-
(2003)
Immunity
, vol.18
, pp. 687-698
-
-
Dequiedt, F.1
Kasler, H.2
Fischle, W.3
Kiermer, V.4
Weinstein, M.5
Herndier, B.G.6
Verdin, E.7
-
41
-
-
84875051261
-
The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells
-
Turtoi A, Mottet D, Matheus N, Dumont B, Peixoto P, Hennequière V, Deroanne C, Colige A, De Pauw E, Bellahcene A. The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. 2012;15:543-54.
-
(2012)
Angiogenesis
, vol.15
, pp. 543-554
-
-
Turtoi, A.1
Mottet, D.2
Matheus, N.3
Dumont, B.4
Peixoto, P.5
Hennequière, V.6
Deroanne, C.7
Colige, A.8
De Pauw, E.9
Bellahcene, A.10
-
42
-
-
84957661931
-
HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies
-
Peixoto P, Blomme A, Costanza B, Ronca R, Rezzola S, Palacios AP, Schoysman L, Boutry S, Goffart N, Peulen O, et al. HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies. Oncogene. 2016;35:4481-94.
-
(2016)
Oncogene
, vol.35
, pp. 4481-4494
-
-
Peixoto, P.1
Blomme, A.2
Costanza, B.3
Ronca, R.4
Rezzola, S.5
Palacios, A.P.6
Schoysman, L.7
Boutry, S.8
Goffart, N.9
Peulen, O.10
-
44
-
-
0033964223
-
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
-
Kao H-Y, Downes M, Ordentlich P, Evans RM. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev. 2000;14:55-66.
-
(2000)
Genes Dev
, vol.14
, pp. 55-66
-
-
Kao, H.-Y.1
Downes, M.2
Ordentlich, P.3
Evans, R.M.4
-
45
-
-
0034641739
-
Identification of a nuclear domain with deacetylase activity
-
Downes M, Ordentlich P, Kao HY, Alvarez JG, Evans RM. Identification of a nuclear domain with deacetylase activity. Proc Natl Acad Sci U S A. 2000;97:10330.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10330
-
-
Downes, M.1
Ordentlich, P.2
Kao, H.Y.3
Alvarez, J.G.4
Evans, R.M.5
-
47
-
-
33947311828
-
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
-
Parra M, Mahmoudi T, Verdin E. Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev. 2007;21:638-43.
-
(2007)
Genes Dev
, vol.21
, pp. 638-643
-
-
Parra, M.1
Mahmoudi, T.2
Verdin, E.3
-
48
-
-
84861215508
-
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation
-
Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, Hoon DS, Forman SJ, Jove R, Riggs AD, Yu H. Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci U S A. 2012;109:7765-9.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 7765-7769
-
-
Lee, H.1
Zhang, P.2
Herrmann, A.3
Yang, C.4
Xin, H.5
Wang, Z.6
Hoon, D.S.7
Forman, S.J.8
Jove, R.9
Riggs, A.D.10
Yu, H.11
-
49
-
-
84878171024
-
STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer
-
Li J, Cui G, Sun L, Wang SJ, Li YL, Meng YG, Guan Z, Fan WS, Li LA, Yang YZ, et al. STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer. Oncol Rep. 2013;30:165-70.
-
(2013)
Oncol Rep
, vol.30
, pp. 165-170
-
-
Li, J.1
Cui, G.2
Sun, L.3
Wang, S.J.4
Li, Y.L.5
Meng, Y.G.6
Guan, Z.7
Fan, W.S.8
Li, L.A.9
Yang, Y.Z.10
-
50
-
-
18744395503
-
STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes
-
Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA. STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes. Proc Natl Acad Sci U S A. 2005;102:6948-53.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6948-6953
-
-
Zhang, Q.1
Wang, H.Y.2
Marzec, M.3
Raghunath, P.N.4
Nagasawa, T.5
Wasik, M.A.6
-
51
-
-
0029666298
-
STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
-
Caldenhoven E, van Dijk TB, Solari R, Armstrong J, Raaijmakers JA, Lammers J-WJ, Koenderman L, de Groot RP. STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J Biol Chem. 1996;271:13221-7.
-
(1996)
J Biol Chem
, vol.271
, pp. 13221-13227
-
-
Caldenhoven, E.1
van Dijk, T.B.2
Solari, R.3
Armstrong, J.4
Raaijmakers, J.A.5
Lammers, J.-W.6
Koenderman, L.7
de Groot, R.P.8
-
52
-
-
84959017357
-
The opposing function of STAT3 as an oncoprotein and tumor suppressor is dictated by the expression status of STAT3β in esophageal squamous cell carcinoma
-
Zhang H-F, Chen Y, Wu C, Wu Z-Y, Tweardy DJ, Alshareef A, Liao L-D, Xue Y-J, Wu J-Y, Chen B. The opposing function of STAT3 as an oncoprotein and tumor suppressor is dictated by the expression status of STAT3β in esophageal squamous cell carcinoma. Clin Cancer Res. 2016;22:691-703.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 691-703
-
-
Zhang, H.-F.1
Chen, Y.2
Wu, C.3
Wu, Z.-Y.4
Tweardy, D.J.5
Alshareef, A.6
Liao, L.-D.7
Xue, Y.-J.8
Wu, J.-Y.9
Chen, B.10
-
53
-
-
36849004821
-
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases
-
Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Surdo PL, Carfí A. Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proc Natl Acad Sci U S A. 2007;104:17335-40.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17335-17340
-
-
Lahm, A.1
Paolini, C.2
Pallaoro, M.3
Nardi, M.C.4
Jones, P.5
Neddermann, P.6
Sambucini, S.7
Bottomley, M.J.8
Surdo, P.L.9
Carfí, A.10
-
54
-
-
45549095066
-
Human HDAC7 harbors a class IIa Histone Deacetylase-specific zinc binding motif and cryptic Deacetylase activity
-
Schuetz A, Min J, Allalihassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski NP, Lewis TA, Maglathin RL. Human HDAC7 harbors a class IIa Histone Deacetylase-specific zinc binding motif and cryptic Deacetylase activity. J Biol Chem. 2008;283:11355-63.
-
(2008)
J Biol Chem
, vol.283
, pp. 11355-11363
-
-
Schuetz, A.1
Min, J.2
Allalihassani, A.3
Schapira, M.4
Shuen, M.5
Loppnau, P.6
Mazitschek, R.7
Kwiatkowski, N.P.8
Lewis, T.A.9
Maglathin, R.L.10
-
55
-
-
40849086606
-
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases
-
Jones P, Altamura S, De FR, Gallinari P, Lahm A, Neddermann P, Rowley M, Serafini S, Steinkühler C. Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases. Bioorg Med Chem Lett. 2008;18:1814-9.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 1814-1819
-
-
Jones, P.1
Altamura, S.2
De, F.R.3
Gallinari, P.4
Lahm, A.5
Neddermann, P.6
Rowley, M.7
Serafini, S.8
Steinkühler, C.9
|