-
1
-
-
20244387299
-
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
-
Adolfsson J, Mansson R, Buza-Vidas N, Hultquist A, Liuba K, Jensen CT et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 2005; 121: 295-306.
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
Mansson, R.2
Buza-Vidas, N.3
Hultquist, A.4
Liuba, K.5
Jensen, C.T.6
-
3
-
-
60749111430
-
Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
-
Stehling-Sun S, Dade J, Nutt SL, DeKoter RP, Camargo FD. Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c. Nat Immunol 2009; 10: 289-296.
-
(2009)
Nat Immunol
, vol.10
, pp. 289-296
-
-
Stehling-Sun, S.1
Dade, J.2
Nutt, S.L.3
Dekoter, R.P.4
Camargo, F.D.5
-
4
-
-
0027992622
-
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
-
Bain G, Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 1994; 79: 885-892.
-
(1994)
Cell
, vol.79
, pp. 885-892
-
-
Bain, G.1
Maandag, E.C.2
Izon, D.J.3
Amsen, D.4
Kruisbeek, A.M.5
Weintraub, B.C.6
-
5
-
-
0031003914
-
Both E12 and E47 allow commitment to the B cell lineage
-
Bain G, Robanus Maandag EC, te Riele HP, Feeney AJ, Sheehy A, Schlissel M et al. Both E12 and E47 allow commitment to the B cell lineage. Immunity 1997; 6: 145-154.
-
(1997)
Immunity
, vol.6
, pp. 145-154
-
-
Bain, G.1
Robanus Maandag, E.C.2
Te Riele, H.P.3
Feeney, A.J.4
Sheehy, A.5
Schlissel, M.6
-
6
-
-
0028148938
-
The helix-loop-helix gene E2A is required for B cell formation
-
Zhuang Y, Soriano P, Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell 1994; 79: 875-884.
-
(1994)
Cell
, vol.79
, pp. 875-884
-
-
Zhuang, Y.1
Soriano, P.2
Weintraub, H.3
-
7
-
-
0029045161
-
Failure of B-cell differentiation in mice lacking the transcription factor EBF
-
Lin H, Grosschedl R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 1995; 376: 263-267.
-
(1995)
Nature
, vol.376
, pp. 263-267
-
-
Lin, H.1
Grosschedl, R.2
-
8
-
-
56349127778
-
Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
-
Dengler HS, Baracho GV, Omori SA, Bruckner S, Arden KC, Castrillon DH et al. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol 2008; 9: 1388-1398.
-
(2008)
Nat Immunol
, vol.9
, pp. 1388-1398
-
-
Dengler, H.S.1
Baracho, G.V.2
Omori, S.A.3
Bruckner, S.4
Arden, K.C.5
Castrillon, D.H.6
-
9
-
-
0027997502
-
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
-
Urbánek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 1994; 79: 901-912.
-
(1994)
Cell
, vol.79
, pp. 901-912
-
-
Urbánek, P.1
Wang, Z.Q.2
Fetka, I.3
Wagner, E.F.4
Busslinger, M.5
-
10
-
-
34249733805
-
High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
-
Kuiper RP, Schoenmakers EF, van Reijmersdal SV, Hehir-Kwa JY, van Kessel AG, van Leeuwen FN et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia 2007; 21: 1258-1266.
-
(2007)
Leukemia
, vol.21
, pp. 1258-1266
-
-
Kuiper, R.P.1
Schoenmakers, E.F.2
Van Reijmersdal, S.V.3
Hehir-Kwa, J.Y.4
Van Kessel, A.G.5
Van Leeuwen, F.N.6
-
11
-
-
82355170632
-
Genomic profiling of B-progenitor acute lymphoblastic leukemia
-
Mullighan CG. Genomic profiling of B-progenitor acute lymphoblastic leukemia. Best Pract Res Clin Haematol 2011; 24: 489-503.
-
(2011)
Best Pract Res Clin Haematol
, vol.24
, pp. 489-503
-
-
Mullighan, C.G.1
-
12
-
-
79952830167
-
Myc roles in hematopoiesis and leukemia
-
Delgado MD, León J. Myc roles in hematopoiesis and leukemia. Genes Cancer 2010; 1: 605-616.
-
(2010)
Genes Cancer
, vol.1
, pp. 605-616
-
-
Delgado, M.D.1
León, J.2
-
13
-
-
84875231561
-
B-lineage transcription factors and cooperating gene lesions required for leukemia development
-
Tijchon E, Havinga J, van Leeuwen FN, Scheijen B. B-lineage transcription factors and cooperating gene lesions required for leukemia development. Leukemia 2013; 27: 541-552.
-
(2013)
Leukemia
, vol.27
, pp. 541-552
-
-
Tijchon, E.1
Havinga, J.2
Van Leeuwen, F.N.3
Scheijen, B.4
-
14
-
-
33644978463
-
Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells
-
Delogu A, Schebesta A, Sun Q, Aschenbrenner K, Perlot T, Busslinger M. Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity 2006; 24: 269-281.
-
(2006)
Immunity
, vol.24
, pp. 269-281
-
-
Delogu, A.1
Schebesta, A.2
Sun, Q.3
Aschenbrenner, K.4
Perlot, T.5
Busslinger, M.6
-
15
-
-
77953289247
-
Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription-independent poising of chromatin
-
Treiber T, Mandel EM, Pott S, Györy I, Firner S, Liu ET et al. Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription-independent poising of chromatin. Immunity 2010; 32: 714-725.
-
(2010)
Immunity
, vol.32
, pp. 714-725
-
-
Treiber, T.1
Mandel, E.M.2
Pott, S.3
Györy, I.4
Firner, S.5
Liu, E.T.6
-
16
-
-
70349329404
-
Class IIa histone deacetylases: Conducting development and differentiation
-
Martin M, Kettmann R, Dequiedt F. Class IIa histone deacetylases: conducting development and differentiation. Int J Dev Biol 2009; 53: 291-301.
-
(2009)
Int J Dev Biol
, vol.53
, pp. 291-301
-
-
Martin, M.1
Kettmann, R.2
Dequiedt, F.3
-
17
-
-
77955686258
-
Regulatory signal transduction pathways for class IIa histone deacetylases
-
Parra M, Verdin E. Regulatory signal transduction pathways for class IIa histone deacetylases. Curr Opin Pharmacol 2010; 10: 454-460.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 454-460
-
-
Parra, M.1
Verdin, E.2
-
18
-
-
84869880178
-
Histone deacetylases and cancer
-
Barneda-Zahonero B, Parra M. Histone deacetylases and cancer. Mol Oncol 2012; 6: 579-589.
-
(2012)
Mol Oncol
, vol.6
, pp. 579-589
-
-
Barneda-Zahonero, B.1
Parra, M.2
-
19
-
-
85045782323
-
The development and potential clinical utility of biomarkers for HDAC inhibitors
-
Shi BW, Xu WF. The development and potential clinical utility of biomarkers for HDAC inhibitors. Drug Discov Ther 2013; 7: 129-136.
-
(2013)
Drug Discov Ther
, vol.7
, pp. 129-136
-
-
Shi, B.W.1
Xu, W.F.2
-
20
-
-
84878489387
-
HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages
-
Barneda-Zahonero B, Román-González L, Collazo O, Rafati H, Islam AB, Bussmann LH et al. HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages. PLoS Genet 2013; 9: e1003503.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003503
-
-
Barneda-Zahonero, B.1
Román-González, L.2
Collazo, O.3
Rafati, H.4
Islam, A.B.5
Bussmann, L.H.6
-
21
-
-
0037728615
-
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCRmediated apoptosis
-
Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG et al. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCRmediated apoptosis. Immunity 2003; 18: 687-698.
-
(2003)
Immunity
, vol.18
, pp. 687-698
-
-
Dequiedt, F.1
Kasler, H.2
Fischle, W.3
Kiermer, V.4
Weinstein, M.5
Herndier, B.G.6
-
22
-
-
34447532435
-
Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes
-
Kasler HG, Verdin E. Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes. Mol Cell Biol 2007; 27: 5184-5200.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5184-5200
-
-
Kasler, H.G.1
Verdin, E.2
-
23
-
-
79954993361
-
Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes
-
Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN et al. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol 2011; 186: 4782-4793.
-
(2011)
J Immunol
, vol.186
, pp. 4782-4793
-
-
Kasler, H.G.1
Young, B.D.2
Mottet, D.3
Lim, H.W.4
Collins, A.M.5
Olson, E.N.6
-
24
-
-
84870512578
-
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance
-
Kasler HG, Lim HW, Mottet D, Collins AM, Lee IS, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. EMBO J 2012; 31: 4453-4465.
-
(2012)
EMBO J
, vol.31
, pp. 4453-4465
-
-
Kasler, H.G.1
Lim, H.W.2
Mottet, D.3
Collins, A.M.4
Lee, I.S.5
Verdin, E.6
-
25
-
-
17144414861
-
Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation
-
Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J Biol Chem 2005; 280: 13762-13770.
-
(2005)
J Biol Chem
, vol.280
, pp. 13762-13770
-
-
Parra, M.1
Kasler, H.2
McKinsey, T.A.3
Olson, E.N.4
Verdin, E.5
-
26
-
-
33947311828
-
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
-
Parra M, Mahmoudi T, Verdin E. Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev 2007; 21: 638-643.
-
(2007)
Genes Dev
, vol.21
, pp. 638-643
-
-
Parra, M.1
Mahmoudi, T.2
Verdin, E.3
-
27
-
-
78449294626
-
PiggyBac transposon mutagenesis: A tool for cancer gene discovery in mice
-
Rad R, Rad L, Wang W, Cadinanos J, Vassiliou G, Rice S et al. PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice. Science 2010; 330: 1104-1107.
-
(2010)
Science
, vol.330
, pp. 1104-1107
-
-
Rad, R.1
Rad, L.2
Wang, W.3
Cadinanos, J.4
Vassiliou, G.5
Rice, S.6
-
28
-
-
84855471990
-
HDAC inhibitors in cancer biology: Emerging mechanisms and clinical applications
-
Khan O, La Thangue NB. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol Cell Biol 2012; 90: 85-94.
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 85-94
-
-
Khan, O.1
La Thangue, N.B.2
-
29
-
-
84877609321
-
Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function
-
Heideman MR, Wilting RH, Yanover E, Velds A, de Jong J, Kerkhoven RM et al. Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function. Blood 2013; 121: 2038-2050.
-
(2013)
Blood
, vol.121
, pp. 2038-2050
-
-
Heideman, M.R.1
Wilting, R.H.2
Yanover, E.3
Velds, A.4
De Jong, J.5
Kerkhoven, R.M.6
-
30
-
-
78249276172
-
Hdac3 is essential for the maintenance of chromatin structure and genome stability
-
Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S et al. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell 2010; 18: 436-447.
-
(2010)
Cancer Cell
, vol.18
, pp. 436-447
-
-
Bhaskara, S.1
Knutson, S.K.2
Jiang, G.3
Chandrasekharan, M.B.4
Wilson, A.J.5
Zheng, S.6
-
31
-
-
84870750886
-
HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance
-
Van Damme M, Crompot E, Meuleman N, Mineur P, Bron D, Lagneaux L et al. HDAC isoenzyme expression is deregulated in chronic lymphocytic leukemia B-cells and has a complex prognostic significance. Epigenetics 2012; 7: 1403-1412.
-
(2012)
Epigenetics
, vol.7
, pp. 1403-1412
-
-
Van Damme, M.1
Crompot, E.2
Meuleman, N.3
Mineur, P.4
Bron, D.5
Lagneaux, L.6
-
32
-
-
84868693336
-
Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays
-
Yan-Fang T, Dong W, Li P, Wen-Li Z, Jun L, Na W et al. Analyzing the gene expression profile of pediatric acute myeloid leukemia with real-time PCR arrays. Cancer Cell Int 2012; 12: 40.
-
(2012)
Cancer Cell Int
, vol.12
, pp. 40
-
-
Yan-Fang, T.1
Dong, W.2
Li, P.3
Wen-Li, Z.4
Jun, L.5
Na, W.6
-
33
-
-
84862804268
-
Histone deacetylase in chronic lymphocytic leukemia
-
Wang JC, Kafeel MI, Avezbakiyev B, Chen C, Sun Y, Rathnasabapathy C et al. Histone deacetylase in chronic lymphocytic leukemia. Oncology 2011; 81: 325-329.
-
(2011)
Oncology
, vol.81
, pp. 325-329
-
-
Wang, J.C.1
Kafeel, M.I.2
Avezbakiyev, B.3
Chen, C.4
Sun, Y.5
Rathnasabapathy, C.6
-
34
-
-
77956309330
-
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia
-
Moreno DA, Scrideli CA, Cortez MA, de Paula Queiroz R, Valera ET, da Silva Silveira V et al. Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia. Br J Haematol 2010; 150: 665-673.
-
(2010)
Br J Haematol
, vol.150
, pp. 665-673
-
-
Moreno, D.A.1
Scrideli, C.A.2
Cortez, M.A.3
De Paula Queiroz, R.4
Valera, E.T.5
Da Silva Silveira, V.6
-
35
-
-
84870007432
-
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia
-
Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C et al. Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discov 2012; 2: 1004-1023.
-
(2012)
Cancer Discov
, vol.2
, pp. 1004-1023
-
-
Geng, H.1
Brennan, S.2
Milne, T.A.3
Chen, W.Y.4
Li, Y.5
Hurtz, C.6
-
36
-
-
84870619467
-
MiR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model
-
Sandhu SK, Volinia S, Costinean S, Galasso M, Neinast R, Santhanam R et al. miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model. Proc Natl Acad Sci USA 2012; 109: 20047-20052.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 20047-20052
-
-
Sandhu, S.K.1
Volinia, S.2
Costinean, S.3
Galasso, M.4
Neinast, R.5
Santhanam, R.6
-
37
-
-
79955934629
-
Gitools: Analysis and visualisation of genomic data using interactive heat-maps
-
Perez-Llamas C, Lopez-Bigas N. Gitools: analysis and visualisation of genomic data using interactive heat-maps. PLoS One 2011; 6: e19541.
-
(2011)
PLoS One
, vol.6
, pp. e19541
-
-
Perez-Llamas, C.1
Lopez-Bigas, N.2
-
39
-
-
33644876958
-
TRANSFAC and its module TRANSCompel: Transcriptional gene regulation in eukaryotes
-
Matys V, Kel-Margoulis OV, Fricke E, Liebich I, Land S, Barre-Dirrie A et al. TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res 2006; 34 (Database issue) D108-D110.
-
(2006)
Nucleic Acids Res
, vol.34
, Issue.DATABASE ISSUE
, pp. D108-D110
-
-
Matys, V.1
Kel-Margoulis, O.V.2
Fricke, E.3
Liebich, I.4
Land, S.5
Barre-Dirrie, A.6
|