Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation

Journal of Biological Chemistry

Volumn 290, Issue 52, 2015, Pages 30762-30770

  Li, Jiang ^a,b   Du, Xingrong ^b,c   Shi, Hao ^b   Deng, Kejing ^b   Chi, Hongbo ^c   Tao, Wufan ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINO ACIDS; MAMMALS; STABILITY; T-CELLS;

ACETYL TRANSFERASE; DEACETYLATION; IMMUNE TOLERANCES; KINASE ACTIVITY; POST-TRANSLATIONAL MODIFICATIONS; REGULATORY T CELLS; SPECIFIC INHIBITORS; TRANSCRIPTIONAL ACTIVITY;

ENZYMES;

PROTEIN MST1; PROTEIN SERINE THREONINE KINASE; SELISISTAT; SIRTUIN 1; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; FOXP3 PROTEIN, MOUSE; MACROPHAGE STIMULATING PROTEIN; ONCOPROTEIN; PROTEIN BINDING; SCATTER FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEACETYLATION; EMBRYO; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; TRANSCRIPTION REGULATION; ACETYLATION; ANIMAL; ENZYMOLOGY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; FORKHEAD TRANSCRIPTION FACTORS; HEPATOCYTE GROWTH FACTOR; HUMANS; MICE; MICE, KNOCKOUT; PROTEIN BINDING; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS; SIRTUIN 1; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTIONAL ACTIVATION;

EID: 84951809536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.668442     Document Type: Article

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