Neuroprotection by histone deacetylase-7 (HDAC7) occurs by inhibition of c-jun expression through a deacetylase-independent mechanism

Journal of Biological Chemistry

Volumn 286, Issue 6, 2011, Pages 4819-4828

  Ma, Chi ^a   D'Mello, Santosh R ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CATALYTIC DOMAINS; CEREBELLAR GRANULE NEURONS; CHEMICAL INHIBITORS; CORTICAL NEURONS; DEACETYLASE; DEACETYLASE ACTIVITY; GENE PROMOTER; GENETIC MODELS; HISTONE DEACETYLASES; HOMOCYSTEIC ACID; HUNTINGTON DISEASE; MEK-ERK SIGNALING; NEURONAL DEATH; NEURONAL SURVIVAL; NEUROPROTECTION; PHARMACOLOGICAL INHIBITION; PHARMACOLOGICAL INHIBITORS; PROTEASOMES; PROTEIN KINASE; STRIATUM; TRANSCRIPTIONAL LEVELS; TRANSGENIC MICE;

CELL DEATH; GENES; POTASSIUM; TRANSCRIPTION;

CALMODULIN;

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 7 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; HOMOCYSTEIC ACID; HUNTINGTIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN C JUN; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE C; RAF PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; HDAC7 PROTEIN, MOUSE; HISTONE DEACETYLASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; HUNTINGTON CHOREA; IMMUNOREACTIVITY; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RAT; ANIMAL; BIOSYNTHESIS; CEREBELLUM; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MALE; METABOLISM; MOUSE; NERVE CELL; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE; WISTAR RAT;

MUS MUSCULUS;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CEREBELLUM; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; MALE; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, WISTAR; TRANSCRIPTION, GENETIC;

EID: 79551532277     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.146860     Document Type: Article

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