-
1
-
-
74549176150
-
CD4+ T cell plasticity-Th2 cells join the crowd
-
Jan 29; PMID: 20152167
-
Zhu J, Paul WE. CD4+ T cell plasticity-Th2 cells join the crowd. Immunity. 2010 Jan 29; 32(1):11–3. https://doi.org/10.1016/j.immuni.2010.01.001 PMID: 20152167
-
(2010)
Immunity
, vol.32
, Issue.1
, pp. 11-13
-
-
Zhu, J.1
Paul, W.E.2
-
2
-
-
79955730734
-
T helper cell differentiation more than just cytokines
-
PMID: 21569915
-
Zygmunt B, Veldhoen M. T helper cell differentiation more than just cytokines. Adv Immunol. 2011; 109:159–96. https://doi.org/10.1016/B978-0-12-387664-5.00005-4 PMID: 21569915
-
(2011)
Adv Immunol
, vol.109
, pp. 159-196
-
-
Zygmunt, B.1
Veldhoen, M.2
-
3
-
-
0033791427
-
Transcriptional regulation of Th1/Th2 polarization
-
Oct; PMID: 11071525
-
Rengarajan J, Szabo SJ, Glimcher LH. Transcriptional regulation of Th1/Th2 polarization. Immunol Today. 2000 Oct; 21(10):479–83. PMID: 11071525
-
(2000)
Immunol Today
, vol.21
, Issue.10
, pp. 479-483
-
-
Rengarajan, J.1
Szabo, S.J.2
Glimcher, L.H.3
-
4
-
-
68949181883
-
TIR8/SIGIRR: An IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Sep; PMID: 19699681
-
Garlanda C, Anders H-J, Mantovani A. TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol. 2009 Sep; 30(9):439–46. https://doi.org/10.1016/j.it.2009.06.001 PMID: 19699681
-
(2009)
Trends Immunol
, vol.30
, Issue.9
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.-J.2
Mantovani, A.3
-
5
-
-
0036570691
-
Is “timing” important for cytokine polarization?
-
May; PMID: 12102745
-
Rhodes SG, Graham SP. Is “timing” important for cytokine polarization? Trends Immunol. 2002 May; 23 (5):246–9. PMID: 12102745
-
(2002)
Trends Immunol
, vol.23
, Issue.5
, pp. 246-249
-
-
Rhodes, S.G.1
Graham, S.P.2
-
6
-
-
0141630493
-
The role of signal transducers and activators of transcription in T inflammatory bowel diseases
-
Sep; PMID: 14555918
-
Mudter J, Neurath MF. The role of signal transducers and activators of transcription in T inflammatory bowel diseases. Inflamm Bowel Dis. 2003 Sep; 9(5):332–7. PMID: 14555918
-
(2003)
Inflamm Bowel Dis
, vol.9
, Issue.5
, pp. 332-337
-
-
Mudter, J.1
Neurath, M.F.2
-
7
-
-
79960035010
-
An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation
-
Jul; PMID: 21632975
-
Yagi R, Zhu J, Paul WE. An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. Int Immunol. 2011 Jul; 23(7):415–20. https://doi.org/10.1093/intimm/dxr029 PMID: 21632975
-
(2011)
Int Immunol
, vol.23
, Issue.7
, pp. 415-420
-
-
Yagi, R.1
Zhu, J.2
Paul, W.E.3
-
8
-
-
0026276529
-
Type 1 T helper and type 2 T helper cells: Functions, regulation and role in protection and disease
-
PMID: 1687725
-
Romagnani S. Type 1 T helper and type 2 T helper cells: functions, regulation and role in protection and disease. Int J Clin Lab Res. 1991; 21(2):152–8. PMID: 1687725
-
(1991)
Int J Clin Lab Res
, vol.21
, Issue.2
, pp. 152-158
-
-
Romagnani, S.1
-
9
-
-
33745808029
-
A three-cell model for activation of naïve T helper cells
-
Aug; PMID: 16867153
-
Corthay A. A three-cell model for activation of naïve T helper cells. Scand J Immunol. 2006 Aug; 64 (2):93–6. https://doi.org/10.1111/j.1365-3083.2006.01782.x PMID: 16867153
-
(2006)
Scand J Immunol
, vol.64
, Issue.2
, pp. 93-96
-
-
Corthay, A.1
-
10
-
-
0037083338
-
Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development
-
Feb 15
-
Smits HH, de Jong EC, Schuitemaker JHN, Geijtenbeek TBH, van Kooyk Y, Kapsenberg ML, et al. Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development. J Immunol Baltim Md 1950. 2002 Feb 15; 168(4):1710–6.
-
(2002)
J Immunol Baltim Md 1950
, vol.168
, Issue.4
, pp. 1710-1716
-
-
Smits, H.H.1
De Jong, E.C.2
Schuitemaker, J.H.N.3
Geijtenbeek, T.B.H.4
Van Kooyk, Y.5
Kapsenberg, M.L.6
-
11
-
-
33751568890
-
IL-27 induces Th1 differentiation via p38 MAPK/T-bet- And intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
-
Dec 1
-
Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol Baltim Md 1950. 2006 Dec 1; 177(11):7579–87.
-
(2006)
J Immunol Baltim Md 1950
, vol.177
, Issue.11
, pp. 7579-7587
-
-
Owaki, T.1
Asakawa, M.2
Fukai, F.3
Mizuguchi, J.4
Yoshimoto, T.5
-
12
-
-
70249093566
-
Expression of Th2-skewed pathology mediators in monocyte-derived type 2 of dendritic cells (DC2)
-
Sep 22; PMID: 19643136
-
Hata M, Takahara S, Tsuzaki H, Ishii Y, Nakata K, Akagawa KS, et al. Expression of Th2-skewed pathology mediators in monocyte-derived type 2 of dendritic cells (DC2). Immunol Lett. 2009 Sep 22; 126(1–2):29–36. https://doi.org/10.1016/j.imlet.2009.07.008 PMID: 19643136
-
(2009)
Immunol Lett
, vol.126
, Issue.1-2
, pp. 29-36
-
-
Hata, M.1
Takahara, S.2
Tsuzaki, H.3
Ishii, Y.4
Nakata, K.5
Akagawa, K.S.6
-
13
-
-
33846013255
-
Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro
-
Jan
-
Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ. Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother Hagerstown Md 1997. 2007 Jan; 30(1):75–82.
-
(2007)
J Immunother Hagerstown Md 1997
, vol.30
, Issue.1
, pp. 75-82
-
-
Wesa, A.1
Kalinski, P.2
Kirkwood, J.M.3
Tatsumi, T.4
Storkus, W.J.5
-
14
-
-
84869193011
-
Immune-Mediated Necrotizing Myopathy Is Characterized by a Specific Th1-M1 Polarized Immune Profile
-
Oct 8
-
Preuße C, Goebel HH, Held J, Wengert O, Scheibe F, Irlbacher K, et al. Immune-Mediated Necrotizing Myopathy Is Characterized by a Specific Th1-M1 Polarized Immune Profile. Am J Pathol. 2012 Oct 8;
-
(2012)
Am J Pathol
-
-
Preuße, C.1
Goebel, H.H.2
Held, J.3
Wengert, O.4
Scheibe, F.5
Irlbacher, K.6
-
15
-
-
67651163404
-
Mina, an Il4 repressor, controls T helper type 2 bias
-
Aug; PMID: 19561615
-
Okamoto M, Van Stry M, Chung L, Koyanagi M, Sun X, Suzuki Y, et al. Mina, an Il4 repressor, controls T helper type 2 bias. Nat Immunol. 2009 Aug; 10(8):872–9. https://doi.org/10.1038/ni.1747 PMID: 19561615
-
(2009)
Nat Immunol
, vol.10
, Issue.8
, pp. 872-879
-
-
Okamoto, M.1
Van Stry, M.2
Chung, L.3
Koyanagi, M.4
Sun, X.5
Suzuki, Y.6
-
16
-
-
77958611660
-
Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
-
Nov; PMID: 20969597
-
Zhu J, Paul WE. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev. 2010 Nov; 238(1):247–62. https://doi.org/10.1111/j.1600-065X.2010.00951.x PMID: 20969597
-
(2010)
Immunol Rev
, vol.238
, Issue.1
, pp. 247-262
-
-
Zhu, J.1
Paul, W.E.2
-
17
-
-
19944433229
-
The capacity of the natural ligands for CD28 to drive IL-4 expression in naïve and antigen-primed CD4+ and CD8+ T cells
-
Jan; PMID: 15569772
-
Bian Y, Hiraoka S-I, Tomura M, Zhou X-Y, Yashiro-Ohtani Y, Mori Y, et al. The capacity of the natural ligands for CD28 to drive IL-4 expression in naïve and antigen-primed CD4+ and CD8+ T cells. Int Immunol. 2005 Jan; 17(1):73–83. https://doi.org/10.1093/intimm/dxh188 PMID: 15569772
-
(2005)
Int Immunol
, vol.17
, Issue.1
, pp. 73-83
-
-
Bian, Y.1
Hiraoka, S.-I.2
Tomura, M.3
Zhou, X.-Y.4
Yashiro-Ohtani, Y.5
Mori, Y.6
-
18
-
-
33845388684
-
Genetic background influences Th cell differentiation by controlling the capacity for IL-2-induced IL-4 production by naive CD4+ T cells
-
Sep 27; PMID: 17035345
-
Yagi J, Arimura Y, Takatori H, Nakajima H, Iwamoto I, Uchiyama T. Genetic background influences Th cell differentiation by controlling the capacity for IL-2-induced IL-4 production by naive CD4+ T cells. Int Immunol. 2006 Sep 27; 18(12):1681–90. https://doi.org/10.1093/intimm/dxl102 PMID: 17035345
-
(2006)
Int Immunol
, vol.18
, Issue.12
, pp. 1681-1690
-
-
Yagi, J.1
Arimura, Y.2
Takatori, H.3
Nakajima, H.4
Iwamoto, I.5
Uchiyama, T.6
-
19
-
-
78649539346
-
IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells
-
Nov; PMID: 21061434
-
Lexberg MH, Taubner A, Albrecht I, Lepenies I, Richter A, Kamradt T, et al. IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells. Eur J Immunol. 2010 Nov; 40(11):3017–27. https://doi.org/10.1002/eji.201040539 PMID: 21061434
-
(2010)
Eur J Immunol
, vol.40
, Issue.11
, pp. 3017-3027
-
-
Lexberg, M.H.1
Taubner, A.2
Albrecht, I.3
Lepenies, I.4
Richter, A.5
Kamradt, T.6
-
20
-
-
84867894231
-
Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors
-
Nov; PMID: 23059426
-
Oestreich KJ, Weinmann AS. Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors. Nat Rev Immunol. 2012 Nov; 12(11):799–804. https://doi.org/10.1038/nri3321 PMID: 23059426
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.11
, pp. 799-804
-
-
Oestreich, K.J.1
Weinmann, A.S.2
-
21
-
-
73949121455
-
Plasticity of T-cell phenotype and function: The T helper type 17 example
-
Feb; PMID: 19922424
-
Peck A, Mellins ED. Plasticity of T-cell phenotype and function: the T helper type 17 example. Immunology. 2010 Feb; 129(2):147–53. https://doi.org/10.1111/j.1365-2567.2009.03189.x PMID: 19922424
-
(2010)
Immunology
, vol.129
, Issue.2
, pp. 147-153
-
-
Peck, A.1
Mellins, E.D.2
-
22
-
-
73149118287
-
Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4
-
Jan; PMID: 20109749
-
Cosmi L, Maggi L, Santarlasci V, Capone M, Cardilicchia E, Frosali F, et al. Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4. J Allergy Clin Immunol. 2010 Jan; 125(1):222–230.e1-4. https://doi.org/10.1016/j.jaci.2009.10.012 PMID: 20109749
-
(2010)
J Allergy Clin Immunol
, vol.125
, Issue.1
, pp. 222-230.e1-e4
-
-
Cosmi, L.1
Maggi, L.2
Santarlasci, V.3
Capone, M.4
Cardilicchia, E.5
Frosali, F.6
-
23
-
-
84880949850
-
Stable T-bet+GATA-3+ Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopatho-logic Inflammation
-
Bhandoola A, editor. Aug 20; PMID: 23976880
-
Peine M, Rausch S, Helmstetter C, Fröhlich A, Hegazy AN, Kühl AA, et al. Stable T-bet+GATA-3+ Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopatho-logic Inflammation. Bhandoola A, editor. PLoS Biol. 2013 Aug 20; 11(8):e1001633. https://doi.org/10.1371/journal.pbio.1001633 PMID: 23976880
-
(2013)
Plos Biol
, vol.11
, Issue.8
-
-
Peine, M.1
Rausch, S.2
Helmstetter, C.3
Fröhlich, A.4
Hegazy, A.N.5
Kühl, A.A.6
-
24
-
-
84921753054
-
Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines
-
Jan 23; PMID: 25477212
-
Becattini S, Latorre D, Mele F, Foglierini M, De Gregorio C, Cassotta A, et al. Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines. Science. 2015 Jan 23; 347 (6220):400–6. https://doi.org/10.1126/science.1260668 PMID: 25477212
-
(2015)
Science
, vol.347
, Issue.6220
, pp. 400-406
-
-
Becattini, S.1
Latorre, D.2
Mele, F.3
Foglierini, M.4
De Gregorio, C.5
Cassotta, A.6
-
25
-
-
0037236203
-
Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes
-
Jan; PMID: 12447360
-
Messi M, Giacchetto I, Nagata K, Lanzavecchia A, Natoli G, Sallusto F. Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes. Nat Immunol. 2003 Jan; 4(1):78–86. https://doi.org/10.1038/ni872 PMID: 12447360
-
(2003)
Nat Immunol
, vol.4
, Issue.1
, pp. 78-86
-
-
Messi, M.1
Giacchetto, I.2
Nagata, K.3
Lanzavecchia, A.4
Natoli, G.5
Sallusto, F.6
-
26
-
-
70149100707
-
HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway
-
Aug 15
-
Chaudhry A, Verghese DA, Das SR, Jameel S, George A, Bal V, et al. HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway. J Immunol Baltim Md 1950. 2009 Aug 15; 183(4):2415–24.
-
(2009)
J Immunol Baltim Md 1950
, vol.183
, Issue.4
, pp. 2415-2424
-
-
Chaudhry, A.1
Verghese, D.A.2
Das, S.R.3
Jameel, S.4
George, A.5
Bal, V.6
-
27
-
-
0042090851
-
Defective T-Cell Activation Is Associated with Augmented Transforming Growth Factor Sensitivity in Mice with Mutations in the Sno Gene
-
Aug 1; PMID: 12861029
-
Pearson-White S, McDuffie M. Defective T-Cell Activation Is Associated with Augmented Transforming Growth Factor Sensitivity in Mice with Mutations in the Sno Gene. Mol Cell Biol. 2003 Aug 1; 23 (15):5446–59. https://doi.org/10.1128/MCB.23.15.5446-5459.2003 PMID: 12861029
-
(2003)
Mol Cell Biol
, vol.23
, Issue.15
, pp. 5446-5459
-
-
Pearson-White, S.1
McDuffie, M.2
-
28
-
-
84867861268
-
BATF–JUN is critical for IRF4-mediated transcription in T cells
-
Sep 19; PMID: 22992523
-
Li P, Spolski R, Liao W, Wang L, Murphy TL, Murphy KM, et al. BATF–JUN is critical for IRF4-mediated transcription in T cells. Nature. 2012 Sep 19; 490(7421):543–6. https://doi.org/10.1038/nature11530 PMID: 22992523
-
(2012)
Nature
, vol.490
, Issue.7421
, pp. 543-546
-
-
Li, P.1
Spolski, R.2
Liao, W.3
Wang, L.4
Murphy, T.L.5
Murphy, K.M.6
-
29
-
-
84859968982
-
Critical Role of STAT5 Transcription Factor Tet-ramerization for Cytokine Responses and Normal Immune Function
-
Apr; PMID: 22520852
-
Lin J-X, Li P, Liu D, Jin HT, He J, Rasheed MAU, et al. Critical Role of STAT5 Transcription Factor Tet-ramerization for Cytokine Responses and Normal Immune Function. Immunity. 2012 Apr; 36(4):586–99. https://doi.org/10.1016/j.immuni.2012.02.017 PMID: 22520852
-
(2012)
Immunity
, vol.36
, Issue.4
, pp. 586-599
-
-
Lin, J.-X.1
Li, P.2
Liu, D.3
Jin, H.T.4
He, J.5
Rasheed, M.A.U.6
-
30
-
-
84894472467
-
Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells
-
Jan 19
-
Saini AS, Shenoy GN, Rath S, Bal V, George A. Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells. Nat Immunol. 2014 Jan 19;
-
(2014)
Nat Immunol
-
-
Saini, A.S.1
Shenoy, G.N.2
Rath, S.3
Bal, V.4
George, A.5
-
31
-
-
84903482588
-
CD40 Signaling Drives B Lymphocytes Into an Intermediate Memory-Like State, Poised Between Naïve and Plasma Cells
-
Jan 31
-
Upadhyay M, Priya GK, Ramesh P, Madhavi MB, Rath S, Bal V, et al. CD40 Signaling Drives B Lymphocytes Into an Intermediate Memory-Like State, Poised Between Naïve and Plasma Cells. J Cell Physiol. 2014 Jan 31;
-
(2014)
J Cell Physiol
-
-
Upadhyay, M.1
Priya, G.K.2
Ramesh, P.3
Madhavi, M.B.4
Rath, S.5
Bal, V.6
-
32
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Dec
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods San Diego Calif. 2001 Dec; 25(4):402–8.
-
(2001)
Methods San Diego Calif
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
33
-
-
78651098371
-
Lasting effects of an impairment of Th1-like immune response in γ-irradiated mice: A resemblance between irradiated mice and aged mice
-
PMID: 21092942
-
Park H-R, Jo S-K. Lasting effects of an impairment of Th1-like immune response in γ-irradiated mice: A resemblance between irradiated mice and aged mice. Cell Immunol. 2011; 267(1):1–8. https://doi.org/10.1016/j.cellimm.2010.10.004 PMID: 21092942
-
(2011)
Cell Immunol
, vol.267
, Issue.1
, pp. 1-8
-
-
Park, H.-R.1
Jo, S.-K.2
-
34
-
-
84924326037
-
Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function
-
Dec 21
-
Rane S, Das R, Ranganathan V, Prabhu S, Das A, Mattoo H, et al. Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function. BMC Biol. 2014 Dec 21; 12(1):106.
-
(2014)
BMC Biol
, vol.12
, Issue.1
, pp. 106
-
-
Rane, S.1
Das, R.2
Ranganathan, V.3
Prabhu, S.4
Das, A.5
Mattoo, H.6
-
35
-
-
0032847380
-
Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice
-
Oct; PMID: 10508801
-
Brewer JP, Kisselgof AB, Martin TR. Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice. Am J Respir Crit Care Med. 1999 Oct; 160(4):1150–6. https://doi.org/10.1164/ajrccm.160.4.9806034 PMID: 10508801
-
(1999)
Am J Respir Crit Care Med
, vol.160
, Issue.4
, pp. 1150-1156
-
-
Brewer, J.P.1
Kisselgof, A.B.2
Martin, T.R.3
-
36
-
-
0038128262
-
Allergen-induced airway disease is mouse strain dependent
-
Jul; PMID: 12626335
-
Whitehead GS, Walker JKL, Berman KG, Foster WM, Schwartz DA. Allergen-induced airway disease is mouse strain dependent. Am J Physiol - Lung Cell Mol Physiol. 2003 Jul; 285(1):L32–42. https://doi.org/10.1152/ajplung.00390.2002 PMID: 12626335
-
(2003)
Am J Physiol—lung Cell Mol Physiol
, vol.285
, Issue.1
, pp. L32-L42
-
-
Whitehead, G.S.1
Walker, J.K.L.2
Berman, K.G.3
Foster, W.M.4
Schwartz, D.A.5
-
37
-
-
0034877815
-
Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter
-
Aug; PMID: 11520464
-
Mohrs M, Shinkai K, Mohrs K, Locksley RM. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity. 2001 Aug; 15(2):303–11. PMID: 11520464
-
(2001)
Immunity
, vol.15
, Issue.2
, pp. 303-311
-
-
Mohrs, M.1
Shinkai, K.2
Mohrs, K.3
Locksley, R.M.4
-
38
-
-
0035731823
-
Schistosoma japonicum egg granuloma formation in the interleukin-4 or interferon-gamma deficient host
-
Jun; PMID: 11412379
-
Hirata M, Kage M, Hara T, Yoneda Y, Zhang M, Fukuma T. Schistosoma japonicum egg granuloma formation in the interleukin-4 or interferon-gamma deficient host. Parasite Immunol. 2001 Jun; 23(6):271–80. PMID: 11412379
-
(2001)
Parasite Immunol
, vol.23
, Issue.6
, pp. 271-280
-
-
Hirata, M.1
Kage, M.2
Hara, T.3
Yoneda, Y.4
Zhang, M.5
Fukuma, T.6
-
39
-
-
0028906593
-
T cell genetic background determines default T helper phenotype development in vitro
-
Feb 1; PMID: 7836924
-
Hsieh CS, Macatonia SE, O’Garra A, Murphy KM. T cell genetic background determines default T helper phenotype development in vitro. J Exp Med. 1995 Feb 1; 181(2):713–21. PMID: 7836924
-
(1995)
J Exp Med
, vol.181
, Issue.2
, pp. 713-721
-
-
Hsieh, C.S.1
Macatonia, S.E.2
O’Garra, A.3
Murphy, K.M.4
-
40
-
-
0032033419
-
Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
-
Mar; PMID: 9529145
-
O’Garra A. Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets. Immunity. 1998 Mar; 8(3):275–83. PMID: 9529145
-
(1998)
Immunity
, vol.8
, Issue.3
, pp. 275-283
-
-
O’Garra, A.1
-
41
-
-
0028874351
-
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model
-
Nov 1; PMID: 7595228
-
Hosken NA, Shibuya K, Heath AW, Murphy KM, O’Garra A. The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model. J Exp Med. 1995 Nov 1; 182(5):1579–84. PMID: 7595228
-
(1995)
J Exp Med
, vol.182
, Issue.5
, pp. 1579-1584
-
-
Hosken, N.A.1
Shibuya, K.2
Heath, A.W.3
Murphy, K.M.4
O’Garra, A.5
-
42
-
-
0034654529
-
CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen
-
Mar 15
-
Rogers PR, Croft M. CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen. J Immunol Baltim Md 1950. 2000 Mar 15; 164(6):2955–63.
-
(2000)
J Immunol Baltim Md 1950
, vol.164
, Issue.6
, pp. 2955-2963
-
-
Rogers, P.R.1
Croft, M.2
-
43
-
-
0032759199
-
The interplay between the duration of TCR and cytokine signaling determines T cell polarization
-
Dec; PMID: 10602020
-
Iezzi G, Scotet E, Scheidegger D, Lanzavecchia A. The interplay between the duration of TCR and cytokine signaling determines T cell polarization. Eur J Immunol. 1999 Dec; 29(12):4092–101. https://doi.org/10.1002/(SICI)1521-4141(199912)29:12<4092::AID-IMMU4092>3.0.CO;2-A PMID: 10602020
-
(1999)
Eur J Immunol
, vol.29
, Issue.12
, pp. 4092-4101
-
-
Iezzi, G.1
Scotet, E.2
Scheidegger, D.3
Lanzavecchia, A.4
-
44
-
-
74549179138
-
Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions
-
Jan; PMID: 20079668
-
Hegazy AN, Peine M, Helmstetter C, Panse I, Fröhlich A, Bergthaler A, et al. Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions. Immunity. 2010 Jan; 32(1):116–28. https://doi.org/10.1016/j.immuni.2009.12.004 PMID: 20079668
-
(2010)
Immunity
, vol.32
, Issue.1
, pp. 116-128
-
-
Hegazy, A.N.1
Peine, M.2
Helmstetter, C.3
Panse, I.4
Fröhlich, A.5
Bergthaler, A.6
-
45
-
-
84892914133
-
Diverting T helper cell trafficking through increased plasticity attenuates autoimmune encephalomyelitis
-
Jan 2; PMID: 24316973
-
Califano D, Sweeney KJ, Le H, VanValkenburgh J, Yager E, O’Connor W, et al. Diverting T helper cell trafficking through increased plasticity attenuates autoimmune encephalomyelitis. J Clin Invest. 2014 Jan 2; 124(1):174–87. https://doi.org/10.1172/JCI70103 PMID: 24316973
-
(2014)
J Clin Invest
, vol.124
, Issue.1
, pp. 174-187
-
-
Califano, D.1
Sweeney, K.J.2
Le, H.3
VanValkenburgh, J.4
Yager, E.5
O’Connor, W.6
-
46
-
-
0034641632
-
Control of T helper cell differentiation - In search of master genes
-
Sep 12
-
Dong C, Flavell RA. Control of T helper cell differentiation — in search of master genes. Sci STKE Signal Transduct Knowl Environ. 2000 Sep 12; 2000(49):pe1.
-
(2000)
Sci STKE Signal Transduct Knowl Environ
, vol.2000
, Issue.49
, pp. pe1
-
-
Dong, C.1
Flavell, R.A.2
-
47
-
-
0036366462
-
TH1 and TH2 cells: A historical perspective
-
Jan; PMID: 11905838
-
Liew FY. TH1 and TH2 cells: a historical perspective. Nat Rev Immunol. 2002 Jan; 2(1):55–60. https://doi.org/10.1038/nri705 PMID: 11905838
-
(2002)
Nat Rev Immunol
, vol.2
, Issue.1
, pp. 55-60
-
-
Liew, F.Y.1
-
48
-
-
70449571945
-
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
-
Oct 20; PMID: 19805038
-
Jenner RG, Townsend MJ, Jackson I, Sun K, Bouwman RD, Young RA, et al. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci. 2009 Oct 20; 106(42):17876–81. https://doi.org/10.1073/pnas.0909357106 PMID: 19805038
-
(2009)
Proc Natl Acad Sci
, vol.106
, Issue.42
, pp. 17876-17881
-
-
Jenner, R.G.1
Townsend, M.J.2
Jackson, I.3
Sun, K.4
Bouwman, R.D.5
Young, R.A.6
-
49
-
-
84871783406
-
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
-
Dec 11; PMID: 23232398
-
Kanhere A, Hertweck A, Bhatia U, Gökmen MR, Perucha E, Jackson I, et al. T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun. 2012 Dec 11; 3:1268. https://doi.org/10.1038/ncomms2260 PMID: 23232398
-
(2012)
Nat Commun
, vol.3
, pp. 1268
-
-
Kanhere, A.1
Hertweck, A.2
Bhatia, U.3
Gökmen, M.R.4
Perucha, E.5
Jackson, I.6
-
50
-
-
1542514782
-
Age-related impaired type 1 T cell responses to influenza: Reduced activation ex vivo, decreased expansion in CTL culture in vitro, and blunted response to influenza vaccination in vivo in the elderly
-
Mar 15
-
Deng Y, Jing Y, Campbell AE, Gravenstein S. Age-related impaired type 1 T cell responses to influenza: reduced activation ex vivo, decreased expansion in CTL culture in vitro, and blunted response to influenza vaccination in vivo in the elderly. J Immunol Baltim Md 1950. 2004 Mar 15; 172(6):3437–46.
-
(2004)
J Immunol Baltim Md 1950
, vol.172
, Issue.6
, pp. 3437-3446
-
-
Deng, Y.1
Jing, Y.2
Campbell, A.E.3
Gravenstein, S.4
-
51
-
-
84880940410
-
Mapping Differentiation under Mixed Culture Conditions Reveals a Tunable Continuum of T Cell Fates
-
Bhandoola A, editor. Jul 30; PMID: 23935451
-
Antebi YE, Reich-Zeliger S, Hart Y, Mayo A, Eizenberg I, Rimer J, et al. Mapping Differentiation under Mixed Culture Conditions Reveals a Tunable Continuum of T Cell Fates. Bhandoola A, editor. PLoS Biol. 2013 Jul 30; 11(7):e1001616. https://doi.org/10.1371/journal.pbio.1001616 PMID: 23935451
-
(2013)
Plos Biol
, vol.11
, Issue.7
-
-
Antebi, Y.E.1
Reich-Zeliger, S.2
Hart, Y.3
Mayo, A.4
Eizenberg, I.5
Rimer, J.6
-
52
-
-
0033625644
-
Survival and cytokine polarization of naive CD4(+) T cells in vitro is largely dependent on exogenous cytokines
-
May; PMID: 10820376
-
Ben-Sasson SZ, Makedonski K, Hu-Li J, Paul WE. Survival and cytokine polarization of naive CD4(+) T cells in vitro is largely dependent on exogenous cytokines. Eur J Immunol. 2000 May; 30(5):1308–17. https://doi.org/10.1002/(SICI)1521-4141(200005)30:5<1308::AID-IMMU1308>3.0.CO;2-I PMID: 10820376
-
(2000)
Eur J Immunol
, vol.30
, Issue.5
, pp. 1308-1317
-
-
Ben-Sasson, S.Z.1
Makedonski, K.2
Hu-Li, J.3
Paul, W.E.4
-
53
-
-
84927084465
-
Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma
-
Apr; PMID: 25630305
-
McAlees JW, Lajoie S, Dienger K, Sproles AA, Richgels PK, Yang Y, et al. Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma. Eur J Immunol. 2015 Apr; 45(4):1019–29. https://doi.org/10.1002/eji.201444778 PMID: 25630305
-
(2015)
Eur J Immunol
, vol.45
, Issue.4
, pp. 1019-1029
-
-
McAlees, J.W.1
Lajoie, S.2
Dienger, K.3
Sproles, A.A.4
Richgels, P.K.5
Yang, Y.6
-
54
-
-
84887549060
-
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells
-
Nov 14; PMID: 24238339
-
Tumes DJ, Onodera A, Suzuki A, Shinoda K, Endo Y, Iwamura C, et al. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. Immunity. 2013 Nov 14; 39(5):819–32. https://doi.org/10.1016/j.immuni.2013.09.012 PMID: 24238339
-
(2013)
Immunity
, vol.39
, Issue.5
, pp. 819-832
-
-
Tumes, D.J.1
Onodera, A.2
Suzuki, A.3
Shinoda, K.4
Endo, Y.5
Iwamura, C.6
-
55
-
-
0028326103
-
CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major
-
Apr 1; PMID: 7908325
-
Wang ZE, Reiner SL, Zheng S, Dalton DK, Locksley RM. CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major. J Exp Med. 1994 Apr 1; 179 (4):1367–71. PMID: 7908325
-
(1994)
J Exp Med
, vol.179
, Issue.4
, pp. 1367-1371
-
-
Wang, Z.E.1
Reiner, S.L.2
Zheng, S.3
Dalton, D.K.4
Locksley, R.M.5
-
56
-
-
53149154521
-
Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression
-
Aug 15
-
Cimmino L, Martins GA, Liao J, Magnusdottir E, Grunig G, Perez RK, et al. Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression. J Immunol Baltim Md 1950. 2008 Aug 15; 181(4):2338–47.
-
(2008)
J Immunol Baltim Md 1950
, vol.181
, Issue.4
, pp. 2338-2347
-
-
Cimmino, L.1
Martins, G.A.2
Liao, J.3
Magnusdottir, E.4
Grunig, G.5
Perez, R.K.6
-
57
-
-
0013590724
-
Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones
-
Dec 1; PMID: 2461563
-
Kelso A, Gough NM. Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones. Proc Natl Acad Sci. 1988 Dec 1; 85(23):9189–93. PMID: 2461563
-
(1988)
Proc Natl Acad Sci
, vol.85
, Issue.23
, pp. 9189-9193
-
-
Kelso, A.1
Gough, N.M.2
-
58
-
-
18244418305
-
T1/ST2 expression is enhanced on CD4+ T cells from schistosome egg-induced granulomas: Analysis of Th cell cytokine coexpression ex vivo
-
Apr 1
-
Löhning M, Grogan JL, Coyle AJ, Yazdanbakhsh M, Meisel C, Gutierrez-Ramos JC, et al. T1/ST2 expression is enhanced on CD4+ T cells from schistosome egg-induced granulomas: analysis of Th cell cytokine coexpression ex vivo. J Immunol Baltim Md 1950. 1999 Apr 1; 162(7):3882–9.
-
(1999)
J Immunol Baltim Md 1950
, vol.162
, Issue.7
, pp. 3882-3889
-
-
Löhning, M.1
Grogan, J.L.2
Coyle, A.J.3
Yazdanbakhsh, M.4
Meisel, C.5
Gutierrez-Ramos, J.C.6
-
59
-
-
0028877056
-
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
-
Nov 1; PMID: 7595206
-
Openshaw P, Murphy EE, Hosken NA, Maino V, Davis K, Murphy K, et al. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J Exp Med. 1995 Nov 1; 182(5):1357–67. PMID: 7595206
-
(1995)
J Exp Med
, vol.182
, Issue.5
, pp. 1357-1367
-
-
Openshaw, P.1
Murphy, E.E.2
Hosken, N.A.3
Maino, V.4
Davis, K.5
Murphy, K.6
-
60
-
-
0026081788
-
Identification and characterization of host-protective T-cell epitopes of a major surface glycoprotein (gp63) from Leishmania major
-
Jan; PMID: 1997399
-
Yang DM, Rogers MV, Liew FY. Identification and characterization of host-protective T-cell epitopes of a major surface glycoprotein (gp63) from Leishmania major. Immunology. 1991 Jan; 72(1):3–9. PMID: 1997399
-
(1991)
Immunology
, vol.72
, Issue.1
, pp. 3-9
-
-
Yang, D.M.1
Rogers, M.V.2
Liew, F.Y.3
-
61
-
-
84975141231
-
Transcription Factors Directing Th2 Differentiation: Gata-3 Plays a Dominant Role
-
Jan 6; PMID: 27207804
-
O’Garra A, Gabryšová L. Transcription Factors Directing Th2 Differentiation: Gata-3 Plays a Dominant Role. J Immunol. 2016 Jan 6; 196(11):4423–5. https://doi.org/10.4049/jimmunol.1600646 PMID: 27207804
-
(2016)
J Immunol
, vol.196
, Issue.11
, pp. 4423-4425
-
-
O’Garra, A.1
Gabryšová, L.2
-
62
-
-
79960429950
-
Transcriptional control of rapid recall by memory CD4 T cells
-
Jul 1
-
Lai W, Yu M, Huang M-N, Okoye F, Keegan AD, Farber DL. Transcriptional control of rapid recall by memory CD4 T cells. J Immunol Baltim Md 1950. 2011 Jul 1; 187(1):133–40.
-
(2011)
J Immunol Baltim Md 1950
, vol.187
, Issue.1
, pp. 133-140
-
-
Lai, W.1
Yu, M.2
Huang, M.-N.3
Okoye, F.4
Keegan, A.D.5
Farber, D.L.6
-
63
-
-
84867827632
-
The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses
-
Oct; PMID: 23041064
-
Zhu J, Jankovic D, Oler AJ, Wei G, Sharma S, Hu G, et al. The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses. Immunity. 2012 Oct; 37(4):660–73. https://doi.org/10.1016/j.immuni.2012.09.007 PMID: 23041064
-
(2012)
Immunity
, vol.37
, Issue.4
, pp. 660-673
-
-
Zhu, J.1
Jankovic, D.2
Oler, A.J.3
Wei, G.4
Sharma, S.5
Hu, G.6
|