Differential control of CD4+ T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma

European Journal of Immunology

Volumn 45, Issue 4, 2015, Pages 1019-1029

  Mcalees, Jaclyn W ^a   Lajoie, Stephane ^a   Dienger, Krista ^a   Sproles, Alyssa A ^a   Richgels, Phoebe K ^a   Yang, Yanfen ^a   Khodoun, Marat ^a,b,c   Azuma, Miyuki ^d   Yagita, Hideo ^e   Fulkerson, Patricia C ^a   Wills Karp, Marsha ^f   Lewkowich, Ian P ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e JUNTENDO UNIVERSITY   (Japan)

^f JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Airway hyperreactivity; Asthma; Cytokines; PD 1 PD L1; Th1 response; Th17 response; Th2 response

Indexed keywords

PROGRAMMED DEATH 1 LIGAND 1; CD274 PROTEIN, MOUSE; CYTOKINE; INTERLEUKIN 12; MONOCLONAL ANTIBODY; PDCD1 PROTEIN, MOUSE; PDCD1LG2 PROTEIN, MOUSE; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 RECEPTOR;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CD4+ T LYMPHOCYTE; CELL POLARITY; CELLS BY BODY ANATOMY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; IMMUNE RESPONSE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TH17 CELL; TH2 CELL; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTHMA; BIOSYNTHESIS; BLOOD; C3H MOUSE; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; DISEASE MODEL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; PYROGLYPHIDAE; SPLEEN; TH1 CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD274; ASTHMA; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; INTERLEUKIN-12; LUNG; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROGRAMMED CELL DEATH 1 RECEPTOR; PYROGLYPHIDAE; SPLEEN; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 84927084465     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201444778     Document Type: Article

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