Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state

Nucleic Acids Research

Volumn 45, Issue 16, 2017, Pages

  Afik, Shaked ^a   Yates, Kathleen B ^b   Bi, Kevin ^b   Darko, Samuel ^c   Godec, Jernej ^b   Gerdemann, Ulrike ^b   Swadling, Leo ^d   Douek, Daniel C ^c   Klenerman, Paul ^d,e   Barnes, Eleanor J ^d,e   Sharpe, Arlene H ^b   Haining, W Nicholas ^b,f,g   Yosef, Nir ^h,i  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g BOSTON CHILDREN S HOSPITAL   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; RNA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTOME; COMPLEMENTARITY DETERMINING REGION; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; CD8+ T LYMPHOCYTE; CELL HETEROGENEITY; COMPLEMENTARITY DETERMINING REGION; EFFECTOR CELL; GENE CONSTRUCT; GENE LIBRARY; GERM LINE; HUMAN; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; RNA TRANSCRIPTION; SOFTWARE; T LYMPHOCYTE SUBPOPULATION; TCR RECONSTRUCTION ALGORITHM FOR PAIRED END SINGLE CELL; YELLOW FEVER VIRUS; ALGORITHM; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; FEMALE; GENE EXPRESSION PROFILING; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; PROCEDURES; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

ALGORITHMS; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MICE, INBRED C57BL; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS; SOFTWARE; YELLOW FEVER VIRUS;

EID: 85031934337     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkx615     Document Type: Article

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