mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis

Molecular Cell

Volumn 68, Issue 2, 2017, Pages 323-335.e6

  Wan, Wei ^a   You, Zhiyuan ^a   Xu, Yinfeng ^a   Zhou, Li ^a   Guan, Zhunlv ^a   Peng, Chao ^b   Wong, Catherine C L ^b   Su, Hua ^a   Zhou, Tianhua ^a   Xia, Hongguang ^a   Liu, Wei ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

autophagy; cell metabolism; lipogenesis; mTORC1; p300

Indexed keywords

HISTONE ACETYLTRANSFERASE PCAF; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; SERINE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; P300-CBP-ASSOCIATED FACTOR; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOPHAGY; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CATABOLISM; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; LIPOGENESIS; MOLECULAR DYNAMICS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RING FINGER MOTIF; ANIMAL; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HEP-G2 CELL LINE; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN DOMAIN;

ANIMALS; AUTOPHAGY; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; LIPOGENESIS; MICE; MULTIPROTEIN COMPLEXES; P300-CBP TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN DOMAINS; TOR SERINE-THREONINE KINASES;

EID: 85031284714     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.09.020     Document Type: Article

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