메뉴 건너뛰기




Volumn 200, Issue 4, 2013, Pages 475-491

Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; RAG GUANOSINE TRIPHOSPHATASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG;

EID: 84874352229     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201209135     Document Type: Article
Times cited : (274)

References (31)
  • 1
    • 84866431363 scopus 로고    scopus 로고
    • Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1
    • Bar-Peled, L., L.D. Schweitzer, R. Zoncu, and D.M. Sabatini. 2012. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1. Cell. 150:1196-1208. http://dx.doi.org/10.1016/j.cell.2012.07.032
    • (2012) Cell. , vol.150 , pp. 1196-1208
    • Bar-Peled, L.1    Schweitzer, L.D.2    Zoncu, R.3    Sabatini, D.M.4
  • 2
    • 33748301944 scopus 로고    scopus 로고
    • Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors
    • Bronisz, A., S.M. Sharma, R. Hu, J. Godlewski, G. Tzivion, K.C. Mansky, and M.C. Ostrowski. 2006. Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Mol. Biol. Cell. 17:3897-3906. http://dx.doi.org/10.1091/mbc.E06-05-0470
    • (2006) Mol. Biol. Cell. , vol.17 , pp. 3897-3906
    • Bronisz, A.1    Sharma, S.M.2    Hu, R.3    Godlewski, J.4    Tzivion, G.5    Mansky, K.C.6    Ostrowski, M.C.7
  • 4
    • 33745745910 scopus 로고    scopus 로고
    • A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast
    • Gao, M., and C.A. Kaiser. 2006. A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat. Cell Biol. 8:657-667. http://dx.doi.org/10.1038/ncb1419
    • (2006) Nat. Cell Biol. , vol.8 , pp. 657-667
    • Gao, M.1    Kaiser, C.A.2
  • 5
    • 80051873144 scopus 로고    scopus 로고
    • Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation
    • Gong, R., L. Li, Y. Liu, P. Wang, H. Yang, L. Wang, J. Cheng, K.L. Guan, and Y. Xu. 2011. Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation. Genes Dev. 25:1668-1673. http://dx.doi.org/10.1101/gad.16968011
    • (2011) Genes Dev. , vol.25 , pp. 1668-1673
    • Gong, R.1    Li, L.2    Liu, Y.3    Wang, P.4    Yang, H.5    Wang, L.6    Cheng, J.7    Guan, K.L.8    Xu, Y.9
  • 8
    • 79953324545 scopus 로고    scopus 로고
    • WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
    • Ho, H., R. Kapadia, S. Al-Tahan, S. Ahmad, and A.K. Ganesan. 2011. WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition. J. Biol. Chem. 286:12509-12523. http://dx.doi.org/10.1074/jbc.M110.200543
    • (2011) J. Biol. Chem. , vol.286 , pp. 12509-12523
    • Ho, H.1    Kapadia, R.2    Al-Tahan, S.3    Ahmad, S.4    Ganesan, A.K.5
  • 10
    • 70349644856 scopus 로고    scopus 로고
    • Atg101, a novel mammalian autophagy protein interacting with Atg13
    • Hosokawa, N., T. Sasaki, S. Iemura, T. Natsume, T. Hara, and N. Mizushima. 2009b. Atg101, a novel mammalian autophagy protein interacting with Atg13. Autophagy. 5:973-979. http://dx.doi.org/10.4161/auto.5.7.9296
    • (2009) Autophagy. , vol.5 , pp. 973-979
    • Hosokawa, N.1    Sasaki, T.2    Iemura, S.3    Natsume, T.4    Hara, T.5    Mizushima, N.6
  • 11
    • 7944235758 scopus 로고    scopus 로고
    • Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
    • Jacinto, E., R. Loewith, A. Schmidt, S. Lin, M.A. Rüegg, A. Hall, and M.N. Hall. 2004. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat. Cell Biol. 6:1122-1128. http://dx.doi.org/10.1038/ncb1183
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1122-1128
    • Jacinto, E.1    Loewith, R.2    Schmidt, A.3    Lin, S.4    Rüegg, M.A.5    Hall, A.6    Hall, M.N.7
  • 12
    • 0037178786 scopus 로고    scopus 로고
    • mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
    • Kim, D.H., D.D. Sarbassov, S.M. Ali, J.E. King, R.R. Latek, H. Erdjument- Bromage, P. Tempst, and D.M. Sabatini. 2002. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell. 110:163-175. http://dx.doi.org/10.1016/S0092-8674(02)00808-5
    • (2002) Cell. , vol.110 , pp. 163-175
    • Kim, D.H.1    Sarbassov, D.D.2    Ali, S.M.3    King, J.E.4    Latek, R.R.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 13
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • Laplante, M., and D.M. Sabatini. 2012. mTOR signaling in growth control and disease. Cell. 149:274-293. http://dx.doi.org/10.1016/j.cell.2012.03.017 Martina, J.A., Y. Chen, M. Gucek, and R. Puertollano. 2012. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy. 8:903-914. http://dx.doi.org/10.4161/auto.19653
    • (2012) Cell. , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 14
    • 84864874958 scopus 로고    scopus 로고
    • MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
    • Martina, J.A., Y. Chen, M. Gucek, and R. Puertollano. 2012. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy. 8:903-914. http://dx.doi.org/10.4161/auto.19653
    • (2012) Autophagy. , vol.8 , pp. 903-914
    • Martina, J.A.1    Chen, Y.2    Gucek, M.3    Puertollano, R.4
  • 16
    • 0037507252 scopus 로고    scopus 로고
    • The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
    • Nojima, H., C. Tokunaga, S. Eguchi, N. Oshiro, S. Hidayat, K. Yoshino, K. Hara, N. Tanaka, J. Avruch, and K. Yonezawa. 2003. The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif. J. Biol. Chem. 278:15461-15464. http://dx.doi.org/10.1074/jbc.C200665200
    • (2003) J. Biol. Chem. , vol.278 , pp. 15461-15464
    • Nojima, H.1    Tokunaga, C.2    Eguchi, S.3    Oshiro, N.4    Hidayat, S.5    Yoshino, K.6    Hara, K.7    Tanaka, N.8    Avruch, J.9    Yonezawa, K.10
  • 17
    • 80052716148 scopus 로고    scopus 로고
    • Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
    • Palmieri, M., S. Impey, H. Kang, A. di Ronza, C. Pelz, M. Sardiello, and A. Ballabio. 2011. Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. Hum. Mol. Genet. 20:3852-3866. http://dx.doi.org/10.1093/hmg/ddr306
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 3852-3866
    • Palmieri, M.1    Impey, S.2    Kang, H.3    di Ronza, A.4    Pelz, C.5    Sardiello, M.6    Ballabio, A.7
  • 20
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak, Y., L. Bar-Peled, R. Zoncu, A.L. Markhard, S. Nada, and D.M. Sabatini. 2010. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 141:290-303. http://dx.doi.org/10.1016/j.cell.2010.02.024
    • (2010) Cell. , vol.141 , pp. 290-303
    • Sancak, Y.1    Bar-Peled, L.2    Zoncu, R.3    Markhard, A.L.4    Nada, S.5    Sabatini, D.M.6
  • 21
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
    • Sarbassov, D.D., S.M. Ali, D.H. Kim, D.A. Guertin, R.R. Latek, H. Erdjument-Bromage, P. Tempst, and D.M. Sabatini. 2004. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14:1296-1302. http://dx.doi.org/10.1016/j.cub.2004.06.054
    • (2004) Curr. Biol. , vol.14 , pp. 1296-1302
    • Sarbassov, D.D.1    Ali, S.M.2    Kim, D.H.3    Guertin, D.A.4    Latek, R.R.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 22
    • 74849083093 scopus 로고    scopus 로고
    • Lysosomal enhancement: a CLEAR answer to cellular degradative needs
    • Sardiello, M., and A. Ballabio. 2009. Lysosomal enhancement: a CLEAR answer to cellular degradative needs. Cell Cycle. 8:4021-4022. http://dx.doi.org/10.4161/cc.8.24.10263
    • (2009) Cell Cycle. , vol.8 , pp. 4021-4022
    • Sardiello, M.1    Ballabio, A.2
  • 24
    • 0038643484 scopus 로고    scopus 로고
    • Rheb promotes cell growth as a component of the insulin/TOR signalling network
    • Saucedo, L.J., X. Gao, D.A. Chiarelli, L. Li, D. Pan, and B.A. Edgar. 2003. Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat. Cell Biol. 5:566-571. http://dx.doi.org/10.1038/ncb996
    • (2003) Nat. Cell Biol. , vol.5 , pp. 566-571
    • Saucedo, L.J.1    Gao, X.2    Chiarelli, D.A.3    Li, L.4    Pan, D.5    Edgar, B.A.6
  • 25
    • 0035831451 scopus 로고    scopus 로고
    • Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B
    • Sekiguchi, T., E. Hirose, N. Nakashima, M. Ii, and T. Nishimoto. 2001. Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J. Biol. Chem. 276:7246-7257. http://dx.doi.org/10.1074/jbc.M004389200
    • (2001) J. Biol. Chem. , vol.276 , pp. 7246-7257
    • Sekiguchi, T.1    Hirose, E.2    Nakashima, N.3    Ii, M.4    Nishimoto, T.5
  • 29
    • 0032248265 scopus 로고    scopus 로고
    • A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work
    • Yasumoto, K., S. Amae, T. Udono, N. Fuse, K. Takeda, and S. Shibahara. 1998. A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work. Pigment Cell Res. 11:329-336. http://dx.doi.org/10.1111/j.1600-0749.1998.tb00491.x
    • (1998) Pigment Cell Res. , vol.11 , pp. 329-336
    • Yasumoto, K.1    Amae, S.2    Udono, T.3    Fuse, N.4    Takeda, K.5    Shibahara, S.6
  • 30
    • 80555143078 scopus 로고    scopus 로고
    • mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
    • Zoncu, R., L. Bar-Peled, A. Efeyan, S. Wang, Y. Sancak, and D.M. Sabatini. 2011a. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. Science. 334:678- 683. http://dx.doi.org/10.1126/science.1207056
    • (2011) Science. , vol.334 , pp. 678-683
    • Zoncu, R.1    Bar-Peled, L.2    Efeyan, A.3    Wang, S.4    Sancak, Y.5    Sabatini, D.M.6
  • 31
    • 78650510609 scopus 로고    scopus 로고
    • mTOR: from growth signal integration to cancer, diabetes and ageing
    • Zoncu, R., A. Efeyan, and D.M. Sabatini. 2011b. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 12:21-35. http://dx.doi.org/10.1038/nrm3025
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.