An integrated methodology for assessing the impact of food matrix and gastrointestinal effects on the biokinetics and cellular toxicity of ingested engineered nanomaterials

Particle and Fibre Toxicology

Volumn 14, Issue 1, 2017, Pages

  DeLoid, Glen M ^a   Wang, Yanli ^a   Kapronezai, Klara ^a   Lorente, Laura Rubio ^a   Zhang, Roujie ^b   Pyrgiotakis, Georgios ^a   Konduru, Nagarjun V ^a   Ericsson, Maria ^c   White, Jason C ^d   De La Torre Roche, Roberto ^d   Xiao, Hang ^b   McClements, David Julian ^a,b   Demokritou, Philip ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Northeast Regional Center for Excellence in Vector Borne Diseases   (United States)

Author keywords

IENM nanotoxicology; Ingested engineered nanomaterial; Nanosafety

Indexed keywords

CORN OIL; FERRIC OXIDE; IRON OXIDE; NANOMATERIAL; FERRIC ION;

ARTICLE; CELL LYSATE; CENTRIFUGATION; COLLOID; CONCENTRATION (PARAMETERS); CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DISPERSITY; DISSOLUTION; EMULSION; EXPOSURE; FOOD; GASTROINTESTINAL TRACT; GOBLET CELL; HAZARD ASSESSMENT; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; INTESTINE CELL; LASER DIFFRACTION; MASS SPECTROMETRY; NANOTOXICOLOGY; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; SIMULATION; SMALL INTESTINE EPITHELIUM; SUPERNATANT; SURFACE CHARGE; TOXICOKINETICS; TRANSMISSION ELECTRON MICROSCOPY; ANATOMIC MODEL; CACO-2 CELL LINE; CELL SURVIVAL; CHEMISTRY; DIGESTION; DRUG EFFECT; EATING; METABOLISM; NANOTECHNOLOGY; ORAL DRUG ADMINISTRATION; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; RISK ASSESSMENT; SOLUBILITY; SURFACE PROPERTY; TIME FACTOR; TOXICOLOGY;

ADMINISTRATION, ORAL; CACO-2 CELLS; CELL SURVIVAL; DIGESTION; EATING; FERRIC COMPOUNDS; GASTROINTESTINAL TRACT; HUMANS; MODELS, ANATOMIC; NANOSTRUCTURES; NANOTECHNOLOGY; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SOLUBILITY; SURFACE PROPERTIES; TIME FACTORS; TOXICOKINETICS; TOXICOLOGY;

EID: 85031045087     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/s12989-017-0221-5     Document Type: Article

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