In vitro gastrointestinal digestion increases the translocation of polystyrene nanoparticles in an in vitro intestinal co-culture model

Nanotoxicology

Volumn 9, Issue 7, 2015, Pages 886-894

  Walczak, Agata P ^a   Kramer, Evelien ^a   Hendriksen, Peter J M ^a   Helsdingen, Richard ^a   Van Der Zande, Meike ^a   Rietjens, Ivonne M C M ^a   Bouwmeester, Hans ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

3Rs principle; ingestion; mucus; protein corona; surface modification

Indexed keywords

NANOPARTICLE; POLYSTYRENE; PROTEIN; PROTEIN CORONA; UNCLASSIFIED DRUG; POLYSTYRENE DERIVATIVE;

ANALYTIC METHOD; ARTICLE; CACO 2 CELL LINE; CELL VIABILITY; CHEMICAL COMPOSITION; CLINICAL ASSESSMENT; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DIGESTION; DRUG BIOAVAILABILITY; HT 29 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINAL TISSUE; MOLECULAR WEIGHT; NANOTECHNOLOGY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN TRANSPORT; RISK ASSESSMENT; BIOAVAILABILITY; BIOLOGICAL MODEL; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; GASTROINTESTINAL TRACT; HT-29 CELL LINE; METABOLISM;

BIOLOGICAL AVAILABILITY; CELL SURVIVAL; COCULTURE TECHNIQUES; DIGESTION; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL TRACT; HT29 CELLS; HUMANS; IN VITRO TECHNIQUES; MODELS, BIOLOGICAL; NANOPARTICLES; POLYSTYRENES; PROTEIN CORONA;

EID: 84942816449     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2014.988664     Document Type: Article

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