Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease

Cell Reports

Volumn 21, Issue 1, 2017, Pages 208-221

  Marnik, Elisabeth A ^a,b   Wang, Xulong ^a   Sproule, Thomas J ^a   Park, Giljun ^a   Christianson, Gregory J ^a   Lane Reticker, Sarah Kate ^a   Jain, Shweta ^c   Duffy, Theodore ^a   Wang, Hongsheng ^c   Carter, Gregory W ^a,b   Morse, Herbert C ^c   Roopenian, Derry C ^a,b  

^a JACKSON LABORATORY   (United States)

^b TUFTS UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

autoimmunity; IL 21; interleukin 21; K BxN; T follicular helper cells; T regulatory cells

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CHEMOKINE; CYTOKINE; INTERLEUKIN 21; INTERLEUKIN 6; NUCLEAR RECEPTOR NUR77; PROTEIN BCL 2; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; NR4A1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL EXPANSION; CELL MATURATION; CONTROLLED STUDY; HELPER CELL; INTESTINE FLORA; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RNA SEQUENCE; THYMUS; TRANSCRIPTOMICS; ANIMAL; AUTOIMMUNITY; B LYMPHOCYTE; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; HUMORAL IMMUNITY; IMMUNOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

AIRE PROTEIN; ANIMALS; ARTHRITIS; AUTOIMMUNITY; B-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION REGULATION; IMMUNITY, HUMORAL; INTERLEUKINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION FACTORS;

EID: 85030720993     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.09.036     Document Type: Article

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