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Volumn 191, Issue 9, 2013, Pages 4581-4588

IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; CYTOKINE; INTERLEUKIN DERIVATIVE;

EID: 84886049045     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300439     Document Type: Article
Times cited : (48)

References (47)
  • 1
    • 42649134105 scopus 로고    scopus 로고
    • Interleukin-21: Basic biology and implications for cancer and autoimmunity
    • Spolski, R., and W. J. Leonard. 2008. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 26: 57-79.
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 57-79
    • Spolski, R.1    Leonard, W.J.2
  • 2
    • 47249097068 scopus 로고    scopus 로고
    • The role of IL-21 in regulating B-cell function in health and disease
    • Ettinger, R., S. Kuchen, and P. E. Lipsky. 2008. The role of IL-21 in regulating B-cell function in health and disease. Immunol. Rev. 223: 60-86.
    • (2008) Immunol. Rev. , vol.223 , pp. 60-86
    • Ettinger, R.1    Kuchen, S.2    Lipsky, P.E.3
  • 5
    • 84861694711 scopus 로고    scopus 로고
    • Follicular helper T cells in immunity and systemic autoimmunity
    • Craft, J. E. 2012. Follicular helper T cells in immunity and systemic autoimmunity. Nat Rev Rheumatol 8: 337-347.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 337-347
    • Craft, J.E.1
  • 6
    • 80052484466 scopus 로고    scopus 로고
    • Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus
    • Li, J., H. F. Pan, H. Cen, J. Tian, Y. Ma, J. H. Tao, and D. Q. Ye. 2011. Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus. Mol. Biol. Rep. 38: 4077-4081.
    • (2011) Mol. Biol. Rep. , vol.38 , pp. 4077-4081
    • Li, J.1    Pan, H.F.2    Cen, H.3    Tian, J.4    Ma, Y.5    Tao, J.H.6    Ye, D.Q.7
  • 8
    • 77953240156 scopus 로고    scopus 로고
    • Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity
    • Yu, D., and C. G. Vinuesa. 2010. Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity. Cell. Mol. Immunol. 7: 198-203.
    • (2010) Cell. Mol. Immunol. , vol.7 , pp. 198-203
    • Yu, D.1    Vinuesa, C.G.2
  • 9
    • 77955371327 scopus 로고    scopus 로고
    • Interleukin-21: A new mediator of inflammation in systemic lupus erythematosus
    • Sarra, M., and G. Monteleone. 2010. Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus. J. Biomed. Biotechnol. 2010: 294582.
    • (2010) J. Biomed. Biotechnol. , vol.2010 , pp. 294582
    • Sarra, M.1    Monteleone, G.2
  • 11
    • 67849120058 scopus 로고    scopus 로고
    • Interleukin-21 as a new therapeutic target for immune-mediated diseases
    • Monteleone, G., F. Pallone, and T. T. Macdonald. 2009. Interleukin-21 as a new therapeutic target for immune-mediated diseases. Trends Pharmacol. Sci. 30: 441-447.
    • (2009) Trends Pharmacol. Sci. , vol.30 , pp. 441-447
    • Monteleone, G.1    Pallone, F.2    Macdonald, T.T.3
  • 12
    • 84863617821 scopus 로고    scopus 로고
    • IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms
    • Nguyen, V., I. Luzina, H. Rus, C. Tegla, C. Chen, and V. Rus. 2012. IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms. J. Immunol. 189: 1081-1093.
    • (2012) J. Immunol. , vol.189 , pp. 1081-1093
    • Nguyen, V.1    Luzina, I.2    Rus, H.3    Tegla, C.4    Chen, C.5    Rus, V.6
  • 13
    • 46749115446 scopus 로고    scopus 로고
    • A fundamental role for Interleukin-21 in the generation of T follicular helper cells
    • Vogelzang, A., H. M. McGuire, D. Yu, J. Sprent, C. R. Mackay, and C. King. 2008. A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity 29: 127-137.
    • (2008) Immunity , vol.29 , pp. 127-137
    • Vogelzang, A.1    McGuire, H.M.2    Yu, D.3    Sprent, J.4    Mackay, C.R.5    King, C.6
  • 15
    • 82055177182 scopus 로고    scopus 로고
    • How T cells earn the follicular rite of passage
    • Vinuesa, C. G., and J. G. Cyster. 2011. How T cells earn the follicular rite of passage. Immunity 35: 671-680.
    • (2011) Immunity , vol.35 , pp. 671-680
    • Vinuesa, C.G.1    Cyster, J.G.2
  • 22
    • 77954500603 scopus 로고    scopus 로고
    • Cutting edge: Il-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner
    • Bessa, J., M. Kopf, and M. F. Bachmann. 2010. Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner. J. Immunol. 184: 4615-4619.
    • (2010) J. Immunol. , vol.184 , pp. 4615-4619
    • Bessa, J.1    Kopf, M.2    Bachmann, M.F.3
  • 24
    • 74949112138 scopus 로고    scopus 로고
    • IL-21 preferentially enhances IL-15mediated homeostatic proliferation of human CD28+ CD8 memory T cells throughout the adult age span
    • Nguyen, H., and N. P. Weng. 2010. IL-21 preferentially enhances IL-15mediated homeostatic proliferation of human CD28+ CD8 memory T cells throughout the adult age span. J. Leukoc. Biol. 87: 43-49.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 43-49
    • Nguyen, H.1    Weng, N.P.2
  • 25
    • 67649171872 scopus 로고    scopus 로고
    • Immunology. A chronic need for IL-21
    • Johnson, L. D., and S. C. Jameson. 2009. Immunology. A chronic need for IL-21. Science 324: 1525-1526.
    • (2009) Science , vol.324 , pp. 1525-1526
    • Johnson, L.D.1    Jameson, S.C.2
  • 26
    • 74949118308 scopus 로고    scopus 로고
    • Editorial: Memory CD8 T cells now join "Club 21"
    • Tagaya, Y. 2010. Editorial: memory CD8 T cells now join "Club 21". J. Leukoc. Biol. 87: 13-15.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 13-15
    • Tagaya, Y.1
  • 28
    • 0018572881 scopus 로고
    • A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation
    • Murphy, E. D., and J. B. Roths. 1979. A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation. Arthritis Rheum. 22: 1188-1194.
    • (1979) Arthritis Rheum. , vol.22 , pp. 1188-1194
    • Murphy, E.D.1    Roths, J.B.2
  • 33
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • Deane, J. A., P. Pisitkun, R. S. Barrett, L. Feigenbaum, T. Town, J. M. Ward, R. A. Flavell, and S. Bolland. 2007. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27: 801-810.
    • (2007) Immunity , vol.27 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6    Flavell, R.A.7    Bolland, S.8
  • 34
    • 79952148676 scopus 로고    scopus 로고
    • CD8+ T regulatory cells express the ly49 class I MHC receptor and are defective in autoimmune prone B6-yaa mice
    • Kim, H. J., X. Wang, S. Radfar, T. J. Sproule, D. C. Roopenian, and H. Cantor. 2011. CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice. Proc. Natl. Acad. Sci. USA 108: 2010-2015.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 2010-2015
    • Kim, H.J.1    Wang, X.2    Radfar, S.3    Sproule, T.J.4    Roopenian, D.C.5    Cantor, H.6
  • 35
    • 36849036211 scopus 로고    scopus 로고
    • IL-21 is produced by th17 cells and drives IL-17 production in a STAT3-dependent manner
    • Wei, L., A. Laurence, K. M. Elias, and J. J. O'Shea. 2007. IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J. Biol. Chem. 282: 34605-34610.
    • (2007) J. Biol. Chem. , vol.282 , pp. 34605-34610
    • Wei, L.1    Laurence, A.2    Elias, K.M.3    O'Shea, J.J.4
  • 38
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
    • Kitamura, D., J. Roes, R. Kühn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350: 423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kühn, R.3    Rajewsky, K.4
  • 39
    • 0035881242 scopus 로고    scopus 로고
    • The role of alpha beta+ T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus
    • Lawson, B. R., S. I. Koundouris, M. Barnhouse, W. Dummer, R. Baccala, D. H. Kono, and A. N. Theofilopoulos. 2001. The role of alpha beta+ T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus. J. Immunol. 167: 2354-2360.
    • (2001) J. Immunol. , vol.167 , pp. 2354-2360
    • Lawson, B.R.1    Koundouris, S.I.2    Barnhouse, M.3    Dummer, W.4    Baccala, R.5    Kono, D.H.6    Theofilopoulos, A.N.7
  • 43
    • 0038824761 scopus 로고    scopus 로고
    • Customized molecular phenotyping by quantitative gene expression and pattern recognition analysis
    • Akilesh, S., D. J. Shaffer, and D. Roopenian. 2003. Customized molecular phenotyping by quantitative gene expression and pattern recognition analysis. Genome Res. 13: 1719-1727.
    • (2003) Genome Res. , vol.13 , pp. 1719-1727
    • Akilesh, S.1    Shaffer, D.J.2    Roopenian, D.3
  • 44
    • 48649083489 scopus 로고    scopus 로고
    • Interleukin 21: A cytokine/ cytokine receptor system that has come of age
    • Leonard, W. J., R. Zeng, and R. Spolski. 2008. Interleukin 21: a cytokine/ cytokine receptor system that has come of age. J. Leukoc. Biol. 84: 348-356.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 348-356
    • Leonard, W.J.1    Zeng, R.2    Spolski, R.3
  • 45
    • 80755136623 scopus 로고    scopus 로고
    • Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells
    • Lu, K. T., Y. Kanno, J. L. Cannons, R. Handon, P. Bible, A. G. Elkahloun, S. M. Anderson, L. Wei, H. Sun, J. J. O'Shea, and P. L. Schwartzberg. 2011. Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity 35: 622-632.
    • (2011) Immunity , vol.35 , pp. 622-632
    • Lu, K.T.1    Kanno, Y.2    Cannons, J.L.3    Handon, R.4    Bible, P.5    Elkahloun, A.G.6    Anderson, S.M.7    Wei, L.8    Sun, H.9    O'Shea, J.J.10    Schwartzberg, P.L.11
  • 46
    • 64849083153 scopus 로고    scopus 로고
    • IL-21 mediates suppressive effects via its induction of IL-10
    • Spolski, R., H. P. Kim, W. Zhu, D. E. Levy, and W. J. Leonard. 2009. IL-21 mediates suppressive effects via its induction of IL-10. J. Immunol. 182: 2859-2867.
    • (2009) J. Immunol. , vol.182 , pp. 2859-2867
    • Spolski, R.1    Kim, H.P.2    Zhu, W.3    Levy, D.E.4    Leonard, W.J.5
  • 47
    • 78650057188 scopus 로고    scopus 로고
    • IL-21 is an immune activator that also mediates suppression via IL-10
    • Spolski, R., and W. J. Leonard. 2010. IL-21 is an immune activator that also mediates suppression via IL-10. Crit. Rev. Immunol. 30: 559-570.
    • (2010) Crit. Rev. Immunol. , vol.30 , pp. 559-570
    • Spolski, R.1    Leonard, W.J.2


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