-
1
-
-
42649134105
-
Interleukin-21: Basic biology and implications for cancer and autoimmunity
-
Spolski, R., and W. J. Leonard. 2008. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 26: 57-79.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
2
-
-
47249097068
-
The role of IL-21 in regulating B-cell function in health and disease
-
Ettinger, R., S. Kuchen, and P. E. Lipsky. 2008. The role of IL-21 in regulating B-cell function in health and disease. Immunol. Rev. 223: 60-86.
-
(2008)
Immunol. Rev.
, vol.223
, pp. 60-86
-
-
Ettinger, R.1
Kuchen, S.2
Lipsky, P.E.3
-
3
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak, J., S. R. Dillon, A. Nelson, A. Hammond, C. Sprecher, J. A. Gross, J. Johnston, K. Madden, W. Xu, J. West, et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408: 57-63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
Hammond, A.4
Sprecher, C.5
Gross, J.A.6
Johnston, J.7
Madden, K.8
Xu, W.9
West, J.10
-
4
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva, R., X. O. Yang, G. Martinez, Y. Zhang, A. D. Panopoulos, L. Ma, K. Schluns, Q. Tian, S. S. Watowich, A. M. Jetten, and C. Dong. 2007. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448: 480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
Schluns, K.7
Tian, Q.8
Watowich, S.S.9
Jetten, A.M.10
Dong, C.11
-
5
-
-
46749115446
-
A fundamental role for interleukin-21 in the generation of T follicular helper cells
-
Vogelzang, A., H. M. McGuire, D. Yu, J. Sprent, C. R. Mackay, and C. King. 2008. A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity 29: 127-137.
-
(2008)
Immunity
, vol.29
, pp. 127-137
-
-
Vogelzang, A.1
McGuire, H.M.2
Yu, D.3
Sprent, J.4
Mackay, C.R.5
King, C.6
-
6
-
-
45149123617
-
Development and characterization of IL-21-producing CD4+ T cells
-
Suto, A., D. Kashiwakuma, S.-I. Kagami, K. Hirose, N. Watanabe, K. Yokote, Y. Saito, T. Nakayama, M. J. Grusby, I. Iwamoto, and H. Nakajima. 2008. Development and characterization of IL-21-producing CD4+ T cells. J. Exp. Med. 205: 1369-1379.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1369-1379
-
-
Suto, A.1
Kashiwakuma, D.2
Kagami, S.-I.3
Hirose, K.4
Watanabe, N.5
Yokote, K.6
Saito, Y.7
Nakayama, T.8
Grusby, M.J.9
Iwamoto, I.10
Nakajima, H.11
-
7
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T., E. Bettelli, W. Gao, A. Awasthi, A. Jäger, T. B. Strom, M. Oukka, and V. K. Kuchroo. 2007. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 448: 484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jäger, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
8
-
-
46749151286
-
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
-
Nurieva, R. I., Y. Chung, D. Hwang, X. O. Yang, H. S. Kang, L. Ma, Y.-H. Wang, S. S. Watowich, A. M. Jetten, Q. Tian, and C. Dong. 2008. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 29: 138-149.
-
(2008)
Immunity
, vol.29
, pp. 138-149
-
-
Nurieva, R.I.1
Chung, Y.2
Hwang, D.3
Yang, X.O.4
Kang, H.S.5
Ma, L.6
Wang, Y.-H.7
Watowich, S.S.8
Jetten, A.M.9
Tian, Q.10
Dong, C.11
-
9
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty, S. 2011. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29: 621-663.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
10
-
-
41549131849
-
T follicular helper (TFH) cells in normal and dysregulated immune responses
-
King, C., S. G. Tangye, and C. R. Mackay. 2008. T follicular helper (TFH) cells in normal and dysregulated immune responses. Annu. Rev. Immunol. 26: 741-766.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 741-766
-
-
King, C.1
Tangye, S.G.2
Mackay, C.R.3
-
11
-
-
61949463911
-
IL-17 and Th17 Cells
-
Korn, T., E. Bettelli, M. Oukka, and V. K. Kuchroo. 2009. IL-17 and Th17 Cells. Annu. Rev. Immunol. 27: 485-517.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
12
-
-
77956273246
-
Proinflammatory T helper type 17 cells are effective B-cell helpers
-
Mitsdoerffer, M., Y. Lee, A. Jäger, H.-J. Kim, T. Korn, J. K. Kolls, H. Cantor, E. Bettelli, and V. K. Kuchroo. 2010. Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc. Natl. Acad. Sci. USA 107: 14292-14297.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14292-14297
-
-
Mitsdoerffer, M.1
Lee, Y.2
Jäger, A.3
Kim, H.-J.4
Korn, T.5
Kolls, J.K.6
Cantor, H.7
Bettelli, E.8
Kuchroo, V.K.9
-
13
-
-
38349178776
-
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
-
Hsu, H.-C., P. Yang, J. Wang, Q. Wu, R. Myers, J. Chen, J. Yi, T. Guentert, A. Tousson, A. L. Stanus, et al. 2008. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat. Immunol. 9: 166-175.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 166-175
-
-
Hsu, H.-C.1
Yang, P.2
Wang, J.3
Wu, Q.4
Myers, R.5
Chen, J.6
Yi, J.7
Guentert, T.8
Tousson, A.9
Stanus, A.L.10
-
14
-
-
60849107595
-
A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
-
Bubier, J. A., T. J. Sproule, O. Foreman, R. Spolski, D. J. Shaffer, H. C. Morse, III, W. J. Leonard, and D. C. Roopenian. 2009. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice. Proc. Natl. Acad. Sci. USA 106: 1518-1523.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1518-1523
-
-
Bubier, J.A.1
Sproule, T.J.2
Foreman, O.3
Spolski, R.4
Shaffer, D.J.5
Morse III, H.C.6
Leonard, W.J.7
Roopenian, D.C.8
-
15
-
-
34247257447
-
Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis
-
Young, D. A., M. Hegen, H. L. M. Ma, M. J. Whitters, L. M. Albert, L. Lowe, M. Senices, P. W. Wu, B. Sibley, Y. Leathurby, et al. 2007. Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis. Arthritis Rheum. 56: 1152-1163.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 1152-1163
-
-
Young, D.A.1
Hegen, M.2
Ma, H.L.M.3
Whitters, M.J.4
Albert, L.M.5
Lowe, L.6
Senices, M.7
Wu, P.W.8
Sibley, B.9
Leathurby, Y.10
-
16
-
-
33947215987
-
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R. Fc reduces disease progression
-
Herber, D., T. P. Brown, S. Liang, D. A. Young, M. Collins, and K. Dunussi-Joannopoulos. 2007. IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J. Immunol. 178: 3822-3830.
-
(2007)
J. Immunol.
, vol.178
, pp. 3822-3830
-
-
Herber, D.1
Brown, T.P.2
Liang, S.3
Young, D.A.4
Collins, M.5
Dunussi-Joannopoulos, K.6
-
17
-
-
84863617821
-
IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell-and B cell-intrinsic mechanisms
-
Nguyen, V., I. Luzina, H. Rus, C. Tegla, C. Chen, and V. Rus. 2012. IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell-and B cell-intrinsic mechanisms. J. Immunol. 189: 1081-1093.
-
(2012)
J. Immunol.
, vol.189
, pp. 1081-1093
-
-
Nguyen, V.1
Luzina, I.2
Rus, H.3
Tegla, C.4
Chen, C.5
Rus, V.6
-
18
-
-
58149279490
-
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
-
Odegard, J. M., B. R. Marks, L. D. DiPlacido, A. C. Poholek, D. H. Kono, C. Dong, R. A. Flavell, and J. Craft. 2008. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J. Exp. Med. 205: 2873-2886.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2873-2886
-
-
Odegard, J.M.1
Marks, B.R.2
Diplacido, L.D.3
Poholek, A.C.4
Kono, D.H.5
Dong, C.6
Flavell, R.A.7
Craft, J.8
-
19
-
-
41549160141
-
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus
-
Sawalha, A. H., K. M. Kaufman, J. A. Kelly, A. J. Adler, T. Aberle, J. Kilpatrick, E. K. Wakeland, Q.-Z. Li, A. E. Wandstrat, D. R. Karp, et al. 2008. Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus. Ann. Rheum. Dis. 67: 458-461.
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 458-461
-
-
Sawalha, A.H.1
Kaufman, K.M.2
Kelly, J.A.3
Adler, A.J.4
Aberle, T.5
Kilpatrick, J.6
Wakeland, E.K.7
Li, Q.-Z.8
Wandstrat, A.E.9
Karp, D.R.10
-
20
-
-
68049110512
-
A polymorphism within IL21R confers risk for systemic lupus erythematosus
-
Webb, R., J. T. Merrill, J. A. Kelly, A. Sestak, K. M. Kaufman, C. D. Langefeld, J. Ziegler, R. P. Kimberly, J. C. Edberg, R. Ramsey-Goldman, et al. 2009. A polymorphism within IL21R confers risk for systemic lupus erythematosus. Arthritis Rheum. 60: 2402-2407.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2402-2407
-
-
Webb, R.1
Merrill, J.T.2
Kelly, J.A.3
Sestak, A.4
Kaufman, K.M.5
Langefeld, C.D.6
Ziegler, J.7
Kimberly, R.P.8
Edberg, J.C.9
Ramsey-Goldman, R.10
-
21
-
-
52949091915
-
IL-21 signaling is critical for the development of type i diabetes in the NOD mouse
-
Spolski, R., M. Kashyap, C. Robinson, Z. Yu, and W. J. Leonard. 2008. IL-21 signaling is critical for the development of type I diabetes in the NOD mouse. Proc. Natl. Acad. Sci. USA 105: 14028-14033.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14028-14033
-
-
Spolski, R.1
Kashyap, M.2
Robinson, C.3
Yu, Z.4
Leonard, W.J.5
-
22
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King, C., A. Ilic, K. Koelsch, and N. Sarvetnick. 2004. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 117: 265-277.
-
(2004)
Cell
, vol.117
, pp. 265-277
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
23
-
-
0030606310
-
Organ-specific disease provoked by systemic autoimmunity
-
Kouskoff, V., A. S. Korganow, V. Duchatelle, C. Degott, C. Benoist, and D. Mathis. 1996. Organ-specific disease provoked by systemic autoimmunity. Cell 87: 811-822.
-
(1996)
Cell
, vol.87
, pp. 811-822
-
-
Kouskoff, V.1
Korganow, A.S.2
Duchatelle, V.3
Degott, C.4
Benoist, C.5
Mathis, D.6
-
24
-
-
0033607499
-
Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
-
Matsumoto, I., A. Staub, C. Benoist, and D. Mathis. 1999. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science 286: 1732-1735.
-
(1999)
Science
, vol.286
, pp. 1732-1735
-
-
Matsumoto, I.1
Staub, A.2
Benoist, C.3
Mathis, D.4
-
25
-
-
0033118675
-
From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins
-
Korganow, A. S., H. Ji, S. Mangialaio, V. Duchatelle, R. Pelanda, T. Martin, C. Degott, H. Kikutani, K. Rajewsky, J. L. Pasquali, et al. 1999. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity 10: 451-461.
-
(1999)
Immunity
, vol.10
, pp. 451-461
-
-
Korganow, A.S.1
Ji, H.2
Mangialaio, S.3
Duchatelle, V.4
Pelanda, R.5
Martin, T.6
Degott, C.7
Kikutani, H.8
Rajewsky, K.9
Pasquali, J.L.10
-
26
-
-
43049170218
-
Vaccine adjuvants alter TCR-based selection thresholds
-
Malherbe, L., L. Mark, N. Fazilleau, L. J. McHeyzer-Williams, and M. G. McHeyzer-Williams. 2008. Vaccine adjuvants alter TCR-based selection thresholds. Immunity 28: 698-709.
-
(2008)
Immunity
, vol.28
, pp. 698-709
-
-
Malherbe, L.1
Mark, L.2
Fazilleau, N.3
McHeyzer-Williams, L.J.4
McHeyzer-Williams, M.G.5
-
27
-
-
77956536476
-
Characterization of the KRN cell transfer model of rheumatoid arthritis (KRNCTM), a chronic yet synchronized version of the K/BxN mouse
-
LaBranche, T. P., C. L. Hickman-Brecks, D. M. Meyer, C. E. Storer, M. I. Jesson, K. M. Shevlin, F. A. Happa, R. A. Barve, D. J. Weiss, J. C. Minnerly, et al. 2010. Characterization of the KRN cell transfer model of rheumatoid arthritis (KRNCTM), a chronic yet synchronized version of the K/BxN mouse. Am. J. Pathol. 177: 1388-1396.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 1388-1396
-
-
Labranche, T.P.1
Hickman-Brecks, C.L.2
Meyer, D.M.3
Storer, C.E.4
Jesson, M.I.5
Shevlin, K.M.6
Happa, F.A.7
Barve, R.A.8
Weiss, D.J.9
Minnerly, J.C.10
-
28
-
-
18344394955
-
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity
-
Kasaian, M. T., M. J. Whitters, L. L. Carter, L. D. Lowe, J. M. Jussif, B. Deng, K. A. Johnson, J. S. Witek, M. Senices, R. F. Konz, et al. 2002. IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity 16: 559-569.
-
(2002)
Immunity
, vol.16
, pp. 559-569
-
-
Kasaian, M.T.1
Whitters, M.J.2
Carter, L.L.3
Lowe, L.D.4
Jussif, J.M.5
Deng, B.6
Johnson, K.A.7
Witek, J.S.8
Senices, M.9
Konz, R.F.10
-
29
-
-
0346496018
-
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells
-
Eberl, G., S. Marmon, M.-J. Sunshine, P. D. Rennert, Y. Choi, and D. R. Littman. 2004. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5: 64-73.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 64-73
-
-
Eberl, G.1
Marmon, S.2
Sunshine, M.-J.3
Rennert, P.D.4
Choi, Y.5
Littman, D.R.6
-
30
-
-
2642655282
-
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
-
Lühder, F. F., P. P. Höglund, J. P. J. Allison, C. C. Benoist, and D. D. Mathis. 1998. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J. Exp. Med. 187: 427-432.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 427-432
-
-
Lühder, F.F.1
Höglund, P.P.2
Allison, J.P.J.3
Benoist, C.C.4
Mathis, D.D.5
-
31
-
-
79959328032
-
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
-
Choi, Y. S., R. Kageyama, D. Eto, T. C. Escobar, R. J. Johnston, L. Monticelli, C. Lao, and S. Crotty. 2011. ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 34: 932-946.
-
(2011)
Immunity
, vol.34
, pp. 932-946
-
-
Choi, Y.S.1
Kageyama, R.2
Eto, D.3
Escobar, T.C.4
Johnston, R.J.5
Monticelli, L.6
Lao, C.7
Crotty, S.8
-
32
-
-
79151486080
-
Th17 cells can provide B cell help in autoantibody induced arthritis
-
Hickman-Brecks, C. L., J. L. Racz, D. M. Meyer, T. P. LaBranche, and P. M. Allen. 2011. Th17 cells can provide B cell help in autoantibody induced arthritis. J. Autoimmun. 36: 65-75.
-
(2011)
J. Autoimmun.
, vol.36
, pp. 65-75
-
-
Hickman-Brecks, C.L.1
Racz, J.L.2
Meyer, D.M.3
Labranche, T.P.4
Allen, P.M.5
-
33
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I. I., B. S. McKenzie, L. Zhou, C. E. Tadokoro, A. Lepelley, J. J. Lafaille, D. J. Cua, and D. R. Littman. 2006. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
34
-
-
77953913586
-
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
-
Wu, H.-J., I. I. Ivanov, J. Darce, K. Hattori, T. Shima, Y. Umesaki, D. R. Littman, C. Benoist, and D. Mathis. 2010. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32: 815-827.
-
(2010)
Immunity
, vol.32
, pp. 815-827
-
-
Wu, H.-J.1
Ivanov, I.I.2
Darce, J.3
Hattori, K.4
Shima, T.5
Umesaki, Y.6
Littman, D.R.7
Benoist, C.8
Mathis, D.9
-
35
-
-
77149142640
-
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
-
Zotos, D. D., J. M. Coquet, Y. Y. Zhang, A. A. Light, K. K. D'Costa, A. A. Kallies, L. M. Corcoran, D. I. Godfrey, K.M. Toellner, M. J. Smyth, et al. 2010. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J. Exp. Med. 207: 365-378.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 365-378
-
-
Zotos, D.D.1
Coquet, J.M.2
Zhang, Y.Y.3
Light, A.A.4
D'costa, K.K.5
Kallies, A.A.6
Corcoran, L.M.7
Godfrey, D.I.8
Toellner, K.M.9
Smyth, M.J.10
-
36
-
-
65249180981
-
A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD252 T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice
-
Jang, E., S.-H. Cho, H. Park, D.-J. Paik, J. M. Kim, and J. Youn. 2009. A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD252 T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice. J. Immunol. 182: 4649-4656.
-
(2009)
J. Immunol.
, vol.182
, pp. 4649-4656
-
-
Jang, E.1
Cho, S.-H.2
Park, H.3
Paik, D.-J.4
Kim, J.M.5
Youn, J.6
-
37
-
-
62849126473
-
The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
-
Fazilleau, N., L. J. McHeyzer-Williams, H. Rosen, and M. G. McHeyzer-Williams. 2009. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat. Immunol. 10: 375-384.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 375-384
-
-
Fazilleau, N.1
McHeyzer-Williams, L.J.2
Rosen, H.3
McHeyzer-Williams, M.G.4
-
38
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki, K., R. Spolski, C. G. Feng, C.-F. Qi, J. Cheng, A. Sher, H. C. Morse, III, C. Liu, P. L. Schwartzberg, and W. J. Leonard. 2002. A critical role for IL-21 in regulating immunoglobulin production. Science 298: 1630-1634.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
Qi, C.-F.4
Cheng, J.5
Sher, A.6
Morse III, H.C.7
Liu, C.8
Schwartzberg, P.L.9
Leonard, W.J.10
-
39
-
-
77149122105
-
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
-
Linterman, M. A., L. Beaton, D. Yu, R. R. Ramiscal, M. Srivastava, J. J. Hogan, N. K. Verma, M. J. Smyth, R. J. Rigby, and C. G. Vinuesa. 2010. IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J. Exp. Med. 207: 353-363.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 353-363
-
-
Linterman, M.A.1
Beaton, L.2
Yu, D.3
Ramiscal, R.R.4
Srivastava, M.5
Hogan, J.J.6
Verma, N.K.7
Smyth, M.J.8
Rigby, R.J.9
Vinuesa, C.G.10
-
40
-
-
77954500603
-
Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner
-
Bessa, J., M. Kopf, and M. F. Bachmann. 2010. Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner. J. Immunol. 184: 4615-4619.
-
(2010)
J. Immunol.
, vol.184
, pp. 4615-4619
-
-
Bessa, J.1
Kopf, M.2
Bachmann, M.F.3
-
41
-
-
84856880967
-
IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice
-
Rankin, A. L., H. Guay, D. Herber, S. A. Bertino, T. A. Duzanski, Y. Carrier, S. Keegan, M. Senices, N. Stedman, M. Ryan, et al. 2012. IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice. J. Immunol. 188: 1656-1667.
-
(2012)
J. Immunol.
, vol.188
, pp. 1656-1667
-
-
Rankin, A.L.1
Guay, H.2
Herber, D.3
Bertino, S.A.4
Duzanski, T.A.5
Carrier, Y.6
Keegan, S.7
Senices, M.8
Stedman, N.9
Ryan, M.10
-
42
-
-
63449096041
-
Follicular helper T cells are required for systemic autoimmunity
-
Linterman, M. A., R. J. Rigby, R. K. Wong, D. Yu, R. Brink, J. L. Cannons, P. L. Schwartzberg,M. C. Cook, G. D.Walters, and C. G. Vinuesa. 2009. Follicular helper T cells are required for systemic autoimmunity. J. Exp. Med. 206: 561-576.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 561-576
-
-
Linterman, M.A.1
Rigby, R.J.2
Wong, R.K.3
Yu, D.4
Brink, R.5
Cannons, J.L.6
Schwartzberg, P.L.7
Cook, M.C.8
Walters, G.D.9
Vinuesa, C.G.10
-
43
-
-
35748930247
-
Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus
-
Bubier, J. A., S. M. Bennett, T. J. Sproule, B. L. Lyons, S. Olland, D. A. Young, and D. C. Roopenian. 2007. Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus. Ann. N. Y. Acad. Sci. 1110: 590-601.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1110
, pp. 590-601
-
-
Bubier, J.A.1
Bennett, S.M.2
Sproule, T.J.3
Lyons, B.L.4
Olland, S.5
Young, D.A.6
Roopenian, D.C.7
-
44
-
-
77954143695
-
Innate IL-17-producing cells: The sentinels of the immune system
-
Cua, D. J., and C. M. Tato. 2010. Innate IL-17-producing cells: the sentinels of the immune system. Nat. Rev. Immunol. 10: 479-489.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
45
-
-
84865718141
-
IL-17-producing gd T cells and innate lymphoid cells
-
Sutton, C. E., L. A. Mielke, and K. H. Mills. 2012. IL-17-producing gd T cells and innate lymphoid cells. Eur. J. Immunol. 42: 2221-2231.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 2221-2231
-
-
Sutton, C.E.1
Mielke, L.A.2
Mills, K.H.3
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