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Volumn 23, Issue 27, 2017, Pages 4003-4011

GABAergic system in action: Connection to gastrointestinal stress-related disorders

Author keywords

Benzodiazepines; GABAergic system; Gastrointestinal system; Stress; Stress related disorders; Therapy

Indexed keywords

2,6 DI TERT BUTYL 4 (3 HYDROXY 2,2 DIMETHYLPROPYL)PHENOL; 3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; ANTALARMIN; BACLOFEN; BENZODIAZEPINE; BICUCULLINE; CORTICOTROPIN RELEASING FACTOR; GABAERGIC RECEPTOR AFFECTING AGENT; GLUTAMATE DECARBOXYLASE; BENZODIAZEPINE DERIVATIVE;

EID: 85029828245     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612823666170209155753     Document Type: Review
Times cited : (12)

References (143)
  • 1
    • 33751021096 scopus 로고    scopus 로고
    • The organisation of the autonomic nervous system:Peripheral connections
    • Furness JB. The organisation of the autonomic nervous system:peripheral connections. Auton Neurosci 2006; 130(1-2): 1-5.
    • (2006) Auton Neurosci , vol.130 , Issue.1-2 , pp. 1-5
    • Furness, J.B.1
  • 2
    • 0029921341 scopus 로고    scopus 로고
    • The Enteric Nervous System
    • Goyal RK, Hirano IH. The Enteric Nervous System. N Engl J Med 1996; 334: 1106-15.
    • (1996) N Engl J Med , vol.334 , pp. 1106-1115
    • Goyal, R.K.1    Hirano, I.H.2
  • 3
    • 50149091101 scopus 로고    scopus 로고
    • Don’t forget to have a “second brain”
    • Rescigno M. Don’t forget to have a “second brain”. Mucosal Immunol 2008; 1: 328-9.
    • (2008) Mucosal Immunol , vol.1 , pp. 328-329
    • Rescigno, M.1
  • 4
    • 0141612894 scopus 로고    scopus 로고
    • Interactions between the enteric nervous system and the immune system: Role of neuropeptides and nutrition
    • Genton L, Kudsk KA. Interactions between the enteric nervous system and the immune system: role of neuropeptides and nutrition. Am J Surgery 2003; 186: 253-8.
    • (2003) Am J Surgery , vol.186 , pp. 253-258
    • Genton, L.1    Kudsk, K.A.2
  • 5
    • 34249007019 scopus 로고
    • Syndrome produced by diverse nocuous agents
    • Selye H. Syndrome produced by diverse nocuous agents. Nature 1936; 138: 32.
    • (1936) Nature , vol.138 , pp. 32
    • Selye, H.1
  • 6
    • 84865513832 scopus 로고    scopus 로고
    • The legacy of Hans Selye and the origins of stress research: A retrospective 75 years after his landmark brief “letter” to the editor of nature
    • Szabo S, Tache Y, Somogyi A. The legacy of Hans Selye and the origins of stress research: a retrospective 75 years after his landmark brief “letter” to the editor of nature. Stress 2012; 15(5): 472-8.
    • (2012) Stress , vol.15 , Issue.5 , pp. 472-478
    • Szabo, S.1    Tache, Y.2    Somogyi, A.3
  • 9
    • 14544269337 scopus 로고    scopus 로고
    • Protection and damage from acute and chronic stress:Allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders
    • McEwen BS. Protection and damage from acute and chronic stress:allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann N Y Acad Sci 2004; 1032: 1-7.
    • (2004) Ann N Y Acad Sci , vol.1032 , pp. 1-7
    • McEwen, B.S.1
  • 10
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien SJ, McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 2009; 10(6): 434-45.
    • (2009) Nat Rev Neurosci , vol.10 , Issue.6 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 11
    • 0036625640 scopus 로고    scopus 로고
    • Neurocircuitry of stress integration: Anatomical pathways regulating the hypothalamo-pituitaryadrenocortical axis of the rat
    • Ziegler DR, Herman JP. Neurocircuitry of stress integration: anatomical pathways regulating the hypothalamo-pituitaryadrenocortical axis of the rat. Integr Comp Biol 2002; 42(3): 541-51.
    • (2002) Integr Comp Biol , vol.42 , Issue.3 , pp. 541-551
    • Ziegler, D.R.1    Herman, J.P.2
  • 12
    • 77957842889 scopus 로고    scopus 로고
    • Corticotropin-releasing factor signaling and visceral response to stress
    • Stengel A, Tache Y. Corticotropin-releasing factor signaling and visceral response to stress. Exp Biol Med (Maywood) 2010; 235(10): 1168-78.
    • (2010) Exp Biol Med (Maywood) , vol.235 , Issue.10 , pp. 1168-1178
    • Stengel, A.1    Tache, Y.2
  • 13
    • 19644388715 scopus 로고    scopus 로고
    • The stressed gut: Contributions of intestinal stress peptides to inflammation and motility
    • Bunnett NW. The stressed gut: contributions of intestinal stress peptides to inflammation and motility. Proc Natl Acad Sci USA 2005; 102(21): 7409-10.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.21 , pp. 7409-7410
    • Bunnett, N.W.1
  • 14
    • 19644369988 scopus 로고    scopus 로고
    • Role of peripheral corticotropin-releasing factor and urocortin II in intestinal inflammation and motility in terminal ileum
    • la Fleur SE, Wick EC, Idumalla PS, Grady EF, Bhargava A. Role of peripheral corticotropin-releasing factor and urocortin II in intestinal inflammation and motility in terminal ileum. Proc Natl Acad Sci USA 2005; 102(21): 7647-52.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.21 , pp. 7647-7652
    • la Fleur, S.E.1    Wick, E.C.2    Idumalla, P.S.3    Grady, E.F.4    Bhargava, A.5
  • 15
    • 5144228822 scopus 로고    scopus 로고
    • Urocortins and the regulation of gastrointestinal motor function and visceral pain
    • Martinez V, Wang L, Million M, Rivier J, Tache Y. Urocortins and the regulation of gastrointestinal motor function and visceral pain. Peptides 2004; 25(10): 1733-44.
    • (2004) Peptides , vol.25 , Issue.10 , pp. 1733-1744
    • Martinez, V.1    Wang, L.2    Million, M.3    Rivier, J.4    Tache, Y.5
  • 16
    • 2942595862 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin Amediated intestinal inflammation
    • Anton PM, Gay J, Mykoniatis A et al. Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin Amediated intestinal inflammation. Proc Natl Acad Sci USA 2004; 101(22): 8503-8.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.22 , pp. 8503-8508
    • Anton, P.M.1    Gay, J.2    Mykoniatis, A.3
  • 17
    • 0037259012 scopus 로고    scopus 로고
    • Comorbidity of irritable bowel syndrome in psychiatric patients: A review
    • Garakani A, Win T, Virk S, Gupta S, Kaplan D, Masand PS. Comorbidity of irritable bowel syndrome in psychiatric patients: a review. Am J Ther 2003; 10(1): 61-7.
    • (2003) Am J Ther , vol.10 , Issue.1 , pp. 61-67
    • Garakani, A.1    Win, T.2    Virk, S.3    Gupta, S.4    Kaplan, D.5    Masand, P.S.6
  • 18
    • 84924804354 scopus 로고    scopus 로고
    • The relationship between irritable bowel syndrome and psychiatric disorders: From molecular changes to clinical manifestations
    • Fadgyas-Stanculete M, Buga AM, Popa-Wagner A, Dumitrascu DL. The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations. J Mol Psychiatry 2014; 2(1): 4.
    • (2014) J Mol Psychiatry , vol.2 , Issue.1 , pp. 4
    • Fadgyas-Stanculete, M.1    Buga, A.M.2    Popa-Wagner, A.3    Dumitrascu, D.L.4
  • 19
    • 84856866840 scopus 로고    scopus 로고
    • Stress and the gut:Pathophysiology, clinical consequences, diagnostic approach and treatment options
    • Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut:pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol 2011; 62(6): 591-9.
    • (2011) J Physiol Pharmacol , vol.62 , Issue.6 , pp. 591-599
    • Konturek, P.C.1    Brzozowski, T.2    Konturek, S.J.3
  • 20
    • 47649110843 scopus 로고    scopus 로고
    • Psychological comorbidity and complexity of gastrointestinal symptoms in clinically diagnosed irritable bowel syndrome patients
    • Mikocka-Walus A, Turnbull D, Moulding N, Wilson I, Andrews JM, Holtmann G. Psychological comorbidity and complexity of gastrointestinal symptoms in clinically diagnosed irritable bowel syndrome patients. J Gastroenterol Hepatol 2008; 23(7 Pt 1): 1137-43.
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.7 , pp. 1137-1143
    • Mikocka-Walus, A.1    Turnbull, D.2    Moulding, N.3    Wilson, I.4    Andrews, J.M.5    Holtmann, G.6
  • 21
    • 80051519503 scopus 로고    scopus 로고
    • Enteric neuronal density contributes to the severity of intestinal inflammation
    • Margolis KG, Stevanovic K, Karamooz N, et al. Enteric neuronal density contributes to the severity of intestinal inflammation. Gastroenterology 2011; 141(2): 588-98, 598.e1-2.
    • (2011) Gastroenterology , vol.141 , Issue.2
    • Margolis, K.G.1    Stevanovic, K.2    Karamooz, N.3
  • 22
    • 77949263115 scopus 로고    scopus 로고
    • Pathogenesis of IBS: Role of inflammation, immunity and neuroimmune interactions
    • Ohman L, Simren M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol 2010; 7(3): 163-73.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , Issue.3 , pp. 163-173
    • Ohman, L.1    Simren, M.2
  • 23
    • 44649102599 scopus 로고    scopus 로고
    • Review article: Molecular, pathological and therapeutic features of human enteric neuropathies
    • Di Nardo G, Blandizzi C, Volta U, et al. Review article: molecular, pathological and therapeutic features of human enteric neuropathies. Aliment Pharmacol Ther 2008; 28(1): 25-42.
    • (2008) Aliment Pharmacol Ther , vol.28 , Issue.1 , pp. 25-42
    • Di Nardo, G.1    Blandizzi, C.2    Volta, U.3
  • 24
    • 0034551381 scopus 로고    scopus 로고
    • GABA in the mammalian enteric nervous system
    • Krantis A. GABA in the mammalian enteric nervous system. News Physiol Sci 2000; 15: 284-90.
    • (2000) News Physiol Sci , vol.15 , pp. 284-290
    • Krantis, A.1
  • 25
    • 80052274158 scopus 로고    scopus 로고
    • Beyond classical benzodiazepines: Novel therapeutic potential of GABAA receptor subtypes
    • Rudolph U, Knoflach F. Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes. Nat Rev Drug Discov 2011; 10(9): 685-97.
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.9 , pp. 685-697
    • Rudolph, U.1    Knoflach, F.2
  • 26
    • 84891123533 scopus 로고    scopus 로고
    • Interneuronal GABAA receptors inside and outside of synapses
    • Ferando I, Mody I. Interneuronal GABAA receptors inside and outside of synapses. Curr Opin Neurobiol 2014; 26: 57-63.
    • (2014) Curr Opin Neurobiol , vol.26 , pp. 57-63
    • Ferando, I.1    Mody, I.2
  • 27
    • 0036259020 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acid (B) receptors:Structure and function
    • Bowery NG, Bettler B, Froestl W, et al. International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acid (B) receptors:structure and function. Pharmacol Rev 2002; 54(2): 247-64.
    • (2002) Pharmacol Rev , vol.54 , Issue.2 , pp. 247-264
    • Bowery, N.G.1    Bettler, B.2    Froestl, W.3
  • 28
    • 54049137689 scopus 로고    scopus 로고
    • International union of pharmacology. LXX. Subtypes of gamma-aminobutyric acid (A) receptors: Classification on the basis of subunit composition, pharmacology, and function
    • Olsen RW, Sieghart W. International union of pharmacology. LXX. Subtypes of gamma-aminobutyric acid (A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update Pharmacol Rev 2008; 60(3): 243-60.
    • (2008) Update Pharmacol Rev , vol.60 , Issue.3 , pp. 243-260
    • Olsen, R.W.1    Sieghart, W.2
  • 29
    • 0036676724 scopus 로고    scopus 로고
    • Medicinal chemistry and molecular pharmacology of GABAC receptors
    • Johnston GAR. Medicinal chemistry and molecular pharmacology of GABAC receptors. Curr Top Med Chem 2000; 2: 903-13.
    • (2000) Curr Top Med Chem , vol.2 , pp. 903-913
    • Johnston, G.A.R.1
  • 30
    • 0035282713 scopus 로고    scopus 로고
    • Structure and function of GABAC receptors: A comparison of native versus recombinant receptors
    • Zhang D, Pan Z-H, Awobuluyi M, Lipton SA. Structure and function of GABAC receptors: a comparison of native versus recombinant receptors. Trends Pharmacol Sci 2001; 22: 121-32.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 121-132
    • Zhang, D.1    Pan, Z.-H.2    Awobuluyi, M.3    Lipton, S.A.4
  • 31
    • 77950494200 scopus 로고    scopus 로고
    • Binding, activation and modulation of Cysloop receptors
    • Miller PS, Smart TG. Binding, activation and modulation of Cysloop receptors. Trends Pharmacol Sci 2010; 31(4): 161-74.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.4 , pp. 161-174
    • Miller, P.S.1    Smart, T.G.2
  • 32
    • 84869992899 scopus 로고    scopus 로고
    • Structure, function, and modulation of GABA(A) receptors
    • Sigel E, Steinmann ME. Structure, function, and modulation of GABA(A) receptors. J Biol Chem 2012; 287(48): 40224-31.
    • (2012) J Biol Chem , vol.287 , Issue.48 , pp. 40224-40231
    • Sigel, E.1    Steinmann, M.E.2
  • 33
    • 0033004375 scopus 로고    scopus 로고
    • Structure and subunit composition of GABA receptors
    • Sieghart W, Fuchs K, Tretter V, et al. Structure and subunit composition of GABA receptors. Neurochem Int 1999; 34: 379-85.
    • (1999) Neurochem Int , vol.34 , pp. 379-385
    • Sieghart, W.1    Fuchs, K.2    Tretter, V.3
  • 34
    • 77949392957 scopus 로고    scopus 로고
    • Regulation of GABAA receptor subunit expression by pharmacological agents
    • Uusi-Oukari M, Korpi ER. Regulation of GABAA receptor subunit expression by pharmacological agents. Pharmacol Rev 2010; 62(1):97-135.
    • (2010) Pharmacol Rev , vol.62 , Issue.1 , pp. 97-135
    • Uusi-Oukari, M.1    Korpi, E.R.2
  • 36
    • 0026612362 scopus 로고
    • The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum
    • Laurie DJ, Seeburg PH, Wisden W. The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum. J Neurosci 1992; 12(3): 1063-76.
    • (1992) J Neurosci , vol.12 , Issue.3 , pp. 1063-1076
    • Laurie, D.J.1    Seeburg, P.H.2    Wisden, W.3
  • 37
    • 0026612363 scopus 로고
    • The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • Wisden W, Laurie DJ, Monyer H, Seeburg PH. The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci 1992; 12(3): 1040-62.
    • (1992) J Neurosci , vol.12 , Issue.3 , pp. 1040-1062
    • Wisden, W.1    Laurie, D.J.2    Monyer, H.3    Seeburg, P.H.4
  • 38
    • 20044396748 scopus 로고    scopus 로고
    • GABA(A) receptor channel pharmacology
    • Johnston GAR. GABA(A) receptor channel pharmacology. Curr Pharm Des 2005; 11(15): 1867-85.
    • (2005) Curr Pharm Des , vol.11 , Issue.15 , pp. 1867-1885
    • Johnston, G.A.R.1
  • 39
    • 84901688723 scopus 로고    scopus 로고
    • GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system
    • Fritschy JM, Panzanelli P. GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system. Eur J Neurosci 2014; 39(11): 1845-65
    • (2014) Eur J Neurosci , vol.39 , Issue.11 , pp. 1845-1865
    • Fritschy, J.M.1    Panzanelli, P.2
  • 40
    • 84937676179 scopus 로고    scopus 로고
    • Zolpidem withdrawal induced uncoupling of GABAA receptors in vitro associated with altered GABAA receptor subunit mRNA expression
    • Jazvinšćak Jembrek M, Vlainić J, Šuran J. Zolpidem withdrawal induced uncoupling of GABAA receptors in vitro associated with altered GABAA receptor subunit mRNA expression. Acta Neurobiol Exp 2015; 75: 160-71.
    • (2015) Acta Neurobiol Exp , vol.75 , pp. 160-171
    • Jazvinšćak Jembrek, M.1    Vlainić, J.2    Šuran, J.3
  • 41
    • 34047132216 scopus 로고    scopus 로고
    • Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with α1β2γ2S subunits of GABAA receptors
    • Peričić D, Švob Štrac D, Jazvinšćak Jembrek M, Vlainić J. Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with α1β2γ2S subunits of GABAA receptors. Naunyn Schmiedebergs Arch Pharmacol 2007; 375: 177-87.
    • (2007) Naunyn Schmiedebergs Arch Pharmacol , vol.375 , pp. 177-187
    • Peričić, D.1    Švob Štrac, D.2    Jazvinšćak Jembrek, M.3    Vlainić, J.4
  • 42
    • 43949093042 scopus 로고    scopus 로고
    • The role of transcriptional and translational mechanisms in flumazenilinduced up-regulation of recombinant GABAA receptors
    • Jazvinšćak Jembrek M, Švob Štrac D, Vlainić J, Peričić D. The role of transcriptional and translational mechanisms in flumazenilinduced up-regulation of recombinant GABAA receptors. Neurosci Res 2008; 61: 234-41.
    • (2008) Neurosci Res , vol.61 , pp. 234-241
    • Jazvinšćak Jembrek, M.1    Švob Štrac, D.2    Vlainić, J.3    Peričić, D.4
  • 43
    • 84947999159 scopus 로고    scopus 로고
    • GABA receptors: Pharmacological potential and pitfalls
    • Jazvinšćak Jembrek M, Vlainić J. GABA receptors: pharmacological potential and pitfalls. Curr Pharm Design 2015; 21(34): 4943-59.
    • (2015) Curr Pharm Design , vol.21 , Issue.34 , pp. 4943-4959
    • Jazvinšćak Jembrek, M.1    Vlainić, J.2
  • 44
    • 33646529626 scopus 로고    scopus 로고
    • Molecular diversity, trafficking and subcelullar localization of GABAB receptors
    • Bettler B, Tiao JY-H. Molecular diversity, trafficking and subcelullar localization of GABAB receptors. Pharmacol Ther 2006; 110:533-43.
    • (2006) Pharmacol Ther , vol.110 , pp. 533-543
    • Bettler, B.1    Tiao, J.Y.-H.2
  • 46
    • 0027241852 scopus 로고
    • Excitatory amino acids: Physiological and pharmacological probes for neuroscience research
    • Shinozaki H, Ishida M. Excitatory amino acids: physiological and pharmacological probes for neuroscience research. Acta Neurobiol Exp (Wars) 1993; 53(1): 43-51.
    • (1993) Acta Neurobiol Exp (Wars) , vol.53 , Issue.1 , pp. 43-51
    • Shinozaki, H.1    Ishida, M.2
  • 47
    • 0346118853 scopus 로고    scopus 로고
    • Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus
    • Kulik A, Vida I, Lujan R, et al. Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. J Neurosci 2003; 23(35):11026-35.
    • (2003) J Neurosci , vol.23 , Issue.35 , pp. 11026-11035
    • Kulik, A.1    Vida, I.2    Lujan, R.3
  • 48
    • 84874599832 scopus 로고    scopus 로고
    • Postsynaptic GABAB receptors enhance extrasynaptic GABAA receptor function in dentate gyrus granule cells
    • Tao W, Higgs MH, Spain WJ, Ransom CB. Postsynaptic GABAB receptors enhance extrasynaptic GABAA receptor function in dentate gyrus granule cells. J Neurosci 2013; 33(9): 3738-43.
    • (2013) J Neurosci , vol.33 , Issue.9 , pp. 3738-3743
    • Tao, W.1    Higgs, M.H.2    Spain, W.J.3    Ransom, C.B.4
  • 49
    • 0032542382 scopus 로고    scopus 로고
    • GABA(B)-receptor subtypes assemble into functional heteromeric complexes
    • Kaupmann K, Malitschek B, Schuler V, et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 1998; 396(6712): 683-7.
    • (1998) Nature , vol.396 , Issue.6712 , pp. 683-687
    • Kaupmann, K.1    Malitschek, B.2    Schuler, V.3
  • 50
    • 0033667466 scopus 로고    scopus 로고
    • A trafficking checkpoint controls GABA(B) receptor heterodimerization
    • Margeta-Mitrovic M, Jan YN, Jan LY. A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron 2000; 27(1): 97-106.
    • (2000) Neuron , vol.27 , Issue.1 , pp. 97-106
    • Margeta-Mitrovic, M.1    Jan, Y.N.2    Jan, L.Y.3
  • 51
    • 4644296105 scopus 로고    scopus 로고
    • Activation mechanism of the heterodimeric GABAB receptor
    • Pin J-P, Kniazeff J, Binet V, et al. Activation mechanism of the heterodimeric GABAB receptor. Biochem Pharmacol 2004; 68:1565-72.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1565-1572
    • Pin, J.-P.1    Kniazeff, J.2    Binet, V.3
  • 52
    • 0032771147 scopus 로고    scopus 로고
    • The N-terminal domain of γ-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding
    • Malitschek B, Schweizer C, Keir M, et al. The N-terminal domain of γ-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Mol Pharmacol 1999; 56(2): 448-54.
    • (1999) Mol Pharmacol , vol.56 , Issue.2 , pp. 448-454
    • Malitschek, B.1    Schweizer, C.2    Keir, M.3
  • 53
    • 41949131778 scopus 로고    scopus 로고
    • Direct detection of the interaction between recombinant soluble extracellular regions in the heterodimeric metabotropic γ-aminobutyric acid receptor
    • Nomura R, Suzuki Y, Kakizuka A, Jingami H. Direct detection of the interaction between recombinant soluble extracellular regions in the heterodimeric metabotropic γ-aminobutyric acid receptor. J Biol Chem 2008; 283(8): 4665-73.
    • (2008) J Biol Chem , vol.283 , Issue.8 , pp. 4665-4673
    • Nomura, R.1    Suzuki, Y.2    Kakizuka, A.3    Jingami, H.4
  • 54
    • 3042753325 scopus 로고    scopus 로고
    • cAMP response element-binding protein, activating transcription factor-4, and upstream stimulatory factor differentially control hippocampal GABABR1a and GABABR1b subunit gene expression through alternative promoters
    • Steiger JL, Bandyopadhyay S, Farb DH, Russek SJ. cAMP response element-binding protein, activating transcription factor-4, and upstream stimulatory factor differentially control hippocampal GABABR1a and GABABR1b subunit gene expression through alternative promoters. J Neurosci 2004; 24(27): 6115-26.
    • (2004) J Neurosci , vol.24 , Issue.27 , pp. 6115-6126
    • Steiger, J.L.1    Bandyopadhyay, S.2    Farb, D.H.3    Russek, S.J.4
  • 55
    • 84890434896 scopus 로고    scopus 로고
    • Structural mechanism of ligand activation in human GABA(B) receptor
    • Geng Y, Bush M, Mosyak L, Wang F, Fan QR. Structural mechanism of ligand activation in human GABA(B) receptor. Nature 2013; 504(7479): 254-9.
    • (2013) Nature , vol.504 , Issue.7479 , pp. 254-259
    • Geng, Y.1    Bush, M.2    Mosyak, L.3    Wang, F.4    Fan, Q.R.5
  • 56
    • 84909643578 scopus 로고    scopus 로고
    • The enteric nervous system and gastrointestinal innervation: Integrated local and central control
    • Furness JB, Callaghan BP, Rivera LR, Cho HJ. The enteric nervous system and gastrointestinal innervation: integrated local and central control. Adv Exp Med Biol 2014; 817: 39-71.
    • (2014) Adv Exp Med Biol , vol.817 , pp. 39-71
    • Furness, J.B.1    Callaghan, B.P.2    Rivera, L.R.3    Cho, H.J.4
  • 58
    • 0037233610 scopus 로고    scopus 로고
    • Neurohumoral control of gastrointestinal motility
    • Hansen MB. Neurohumoral control of gastrointestinal motility. Physiol Res 2003; 52: 1-30.
    • (2003) Physiol Res , vol.52 , pp. 1-30
    • Hansen, M.B.1
  • 59
    • 0242321832 scopus 로고    scopus 로고
    • Exciting guts with GABA
    • Goaillard JM, Marder E. Exciting guts with GABA. Nat Neurosci 2003; 6(11): 1121-2.
    • (2003) Nat Neurosci , vol.6 , Issue.11 , pp. 1121-1122
    • Goaillard, J.M.1    Marder, E.2
  • 60
    • 84947998102 scopus 로고    scopus 로고
    • Regulation of GABA Neurotransmission by Glutamic Acid Decarboxylase (GAD)
    • Modi JP, Prentice H, Wu JY. Regulation of GABA Neurotransmission by Glutamic Acid Decarboxylase (GAD). Curr Pharm Design 2015; 21(34): 4939-42.
    • (2015) Curr Pharm Design , vol.21 , Issue.34 , pp. 4939-4942
    • Modi, J.P.1    Prentice, H.2    Wu, J.Y.3
  • 61
    • 0019942240 scopus 로고
    • Release of gammaaminobutyric acid from cat colon
    • Taniyama, K, Kusunoki M, Saito N, Tanaka C. Release of gammaaminobutyric acid from cat colon. Science 1982; 217: 1038-40.
    • (1982) Science , vol.217 , pp. 1038-1040
    • Taniyama, K.1    Kusunoki, M.2    Saito, N.3    Tanaka, C.4
  • 62
    • 0035989132 scopus 로고    scopus 로고
    • Neuronal and glial localization of GABA transporter immunoreactivity in the myenteric plexus
    • Fletcher EL, Clark MJ, Furness JB. Neuronal and glial localization of GABA transporter immunoreactivity in the myenteric plexus. Cell Tissue Res 2002; 308(3): 339-46.
    • (2002) Cell Tissue Res , vol.308 , Issue.3 , pp. 339-346
    • Fletcher, E.L.1    Clark, M.J.2    Furness, J.B.3
  • 63
    • 84939869408 scopus 로고    scopus 로고
    • GABA and GABA receptors in the gastrointestinal tract: From motility to inflammation
    • Auteri M, Zizzo MG, Serio R. GABA and GABA receptors in the gastrointestinal tract: from motility to inflammation. Pharmacol Res 2015; 93: 11-21.
    • (2015) Pharmacol Res , vol.93 , pp. 11-21
    • Auteri, M.1    Zizzo, M.G.2    Serio, R.3
  • 64
    • 27144520538 scopus 로고    scopus 로고
    • Expression of rice glutamate decarboxylase in Bifidobacterium longum enhances gammaaminobutyric acid production
    • Park K B, Ji GE, Park MS, Oh SH. Expression of rice glutamate decarboxylase in Bifidobacterium longum enhances gammaaminobutyric acid production. Biotechnol Lett 2005; 27: 1681-4.
    • (2005) Biotechnol Lett , vol.27 , pp. 1681-1684
    • Park, K.B.1    Ji, G.E.2    Park, M.S.3    Oh, S.H.4
  • 65
    • 0029658087 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of GABAB receptors in the rat gastrointestinal tract
    • Nakajima K, Tooyama I, Kuriyama K, Kimura H. Immunohistochemical demonstration of GABAB receptors in the rat gastrointestinal tract. Neurochem Res 1996; 21: 211-5.
    • (1996) Neurochem Res , vol.21 , pp. 211-215
    • Nakajima, K.1    Tooyama, I.2    Kuriyama, K.3    Kimura, H.4
  • 66
    • 0029952017 scopus 로고    scopus 로고
    • Identification of the GABAA receptor alpha-subunit mRNA in rat intestine
    • Zeiter DK, Li X, Broussard DL. Identification of the GABAA receptor alpha-subunit mRNA in rat intestine. Brain Res Mol Brain Res 1996; 39: 241-4.
    • (1996) Brain Res Mol Brain Res , vol.39 , pp. 241-244
    • Zeiter, D.K.1    Li, X.2    Broussard, D.L.3
  • 67
    • 0032805312 scopus 로고    scopus 로고
    • GABA(A) receptor subunit messenger RNA expression in the enteric nervous system of the rat: Implications for functional diversity of enteric GABA(A) receptors
    • Poulter MO, Singhal R, Brown LA, Krantis A. GABA(A) receptor subunit messenger RNA expression in the enteric nervous system of the rat: implications for functional diversity of enteric GABA(A) receptors. Neuroscience 1999; 93: 1159-65.
    • (1999) Neuroscience , vol.93 , pp. 1159-1165
    • Poulter, M.O.1    Singhal, R.2    Brown, L.A.3    Krantis, A.4
  • 68
    • 84904985821 scopus 로고    scopus 로고
    • Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon
    • Seifi M, Brown JF, Mills J, et al. Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon. J Neurosci 2014; 34(31): 10361-78.
    • (2014) J Neurosci , vol.34 , Issue.31 , pp. 10361-10378
    • Seifi, M.1    Brown, J.F.2    Mills, J.3
  • 69
    • 0024472965 scopus 로고
    • The role of GABAA receptor function in peristaltic activity of the guinea-pig ileum: A comparative study with bicuculline, SR 95531 and picrotoxinin
    • Tonini M, De Petris G, Onori L, Manzo L, Rizzi CA, Crema A. The role of GABAA receptor function in peristaltic activity of the guinea-pig ileum: a comparative study with bicuculline, SR 95531 and picrotoxinin. Br J Pharmacol 1989; 97: 556-62.
    • (1989) Br J Pharmacol , vol.97 , pp. 556-562
    • Tonini, M.1    De Petris, G.2    Onori, L.3    Manzo, L.4    Rizzi, C.A.5    Crema, A.6
  • 70
    • 0024798275 scopus 로고
    • An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit
    • Tonini M, Crema A, Frigo GM, et al. An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit. Br J Pharmacol 1989; 98: 1109-18.
    • (1989) Br J Pharmacol , vol.98 , pp. 1109-1118
    • Tonini, M.1    Crema, A.2    Frigo, G.M.3
  • 71
    • 0027251728 scopus 로고
    • GABA mediation of the dual effects of somatostatin on guinea pig ileal myenteric cholinergic transmission
    • Roberts DJ, Hasler WL, Owyang C. GABA mediation of the dual effects of somatostatin on guinea pig ileal myenteric cholinergic transmission. Am J Physiol 1993; 264: 953-60.
    • (1993) Am J Physiol , vol.264 , pp. 953-960
    • Roberts, D.J.1    Hasler, W.L.2    Owyang, C.3
  • 72
    • 0027472531 scopus 로고
    • Excitatory and inhibitory responses mediated by GABAA and GABAB receptors in guinea pig distal colon
    • Minocha A, Galligan JJ. Excitatory and inhibitory responses mediated by GABAA and GABAB receptors in guinea pig distal colon. Eur J Pharmacol 1993; 230: 187-93.
    • (1993) Eur J Pharmacol , vol.230 , pp. 187-193
    • Minocha, A.1    Galligan, J.J.2
  • 73
    • 0037435809 scopus 로고    scopus 로고
    • Functional evidence for a role of GABA receptors in modulating nerve activities of circular smooth muscle from rat colon in vitro
    • Bayer S, Jellali A, Crenner F, Aunis D, Angel F. Functional evidence for a role of GABA receptors in modulating nerve activities of circular smooth muscle from rat colon in vitro. Life Sci 2003; 72: 1481-93.
    • (2003) Life Sci , vol.72 , pp. 1481-1493
    • Bayer, S.1    Jellali, A.2    Crenner, F.3    Aunis, D.4    Angel, F.5
  • 74
    • 0023896732 scopus 로고
    • Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gammaaminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine
    • Taniyama K, Hashimoto S, Hanada S, Tanaka C. Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gammaaminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine. J Pharmacol Exp Ther 1988; 245(1): 250-6.
    • (1988) J Pharmacol Exp Ther , vol.245 , Issue.1 , pp. 250-256
    • Taniyama, K.1    Hashimoto, S.2    Hanada, S.3    Tanaka, C.4
  • 75
    • 84943754733 scopus 로고    scopus 로고
    • Role of Na-K-2Cl symporter in GABA-evoked excitation in rat enteric neurons
    • Liu S, Ji T, Ren W, Qu MH, Zhu JX, Wood JD. Role of Na-K-2Cl symporter in GABA-evoked excitation in rat enteric neurons. FASEB J 2013; 27: 1160.5
    • (2013) FASEB J , vol.27 , pp. 1160.5
    • Liu, S.1    Ji, T.2    Ren, W.3    Qu, M.H.4    Zhu, J.X.5    Wood, J.D.6
  • 76
    • 34249734264 scopus 로고    scopus 로고
    • Functional evidence for GABA as modulator of the contractility of the longitudinal muscle in mouse duodenum: Role of GABA(A) and GABA(C) receptors
    • Zizzo MG, Mule F, Serio R. Functional evidence for GABA as modulator of the contractility of the longitudinal muscle in mouse duodenum: role of GABA(A) and GABA(C) receptors. Neuropharmacology 2007; 52(8): 1685-90.
    • (2007) Neuropharmacology , vol.52 , Issue.8 , pp. 1685-1690
    • Zizzo, M.G.1    Mule, F.2    Serio, R.3
  • 77
    • 84865858575 scopus 로고    scopus 로고
    • A gut feeling about GABA: Focus on GABAB receptors
    • Hyland NP, Cryan JF. A gut feeling about GABA: focus on GABAB receptors. Frontiers in pharmacology 2010; 1: 124.
    • (2010) Frontiers in pharmacology , vol.1 , pp. 124
    • Hyland, N.P.1    Cryan, J.F.2
  • 78
    • 0021327131 scopus 로고
    • Inhibition of calcium spikes and transmitter release by gamma-aminobutyric acid in the guinea-pig myenteric plexus
    • Cherubini E, North RA. Inhibition of calcium spikes and transmitter release by gamma-aminobutyric acid in the guinea-pig myenteric plexus. Br J Pharmacol 1984; 82: 101-5.
    • (1984) Br J Pharmacol , vol.82 , pp. 101-105
    • Cherubini, E.1    North, R.A.2
  • 79
    • 0034031410 scopus 로고    scopus 로고
    • A subtype of the gamma-aminobutyric acid(B) receptor regulates cholinergic twitch response in the guinea pig ileum
    • Marcoli M, Scarrone S, Maura G, Bonanno G, Raiteri M. A subtype of the gamma-aminobutyric acid(B) receptor regulates cholinergic twitch response in the guinea pig ileum. J Pharmacol Exp Ther 2000; 293: 42-7.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 42-47
    • Marcoli, M.1    Scarrone, S.2    Maura, G.3    Bonanno, G.4    Raiteri, M.5
  • 80
    • 0028175724 scopus 로고
    • [3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon
    • Krantis A, Tufts K, Nichols K, Morris GP. [3H]GABA uptake and GABA localization in mucosal endocrine cells of the rat stomach and colon. J Auton Nerv Syst 1994; 47(3): 225-32.
    • (1994) J Auton Nerv Syst , vol.47 , Issue.3 , pp. 225-232
    • Krantis, A.1    Tufts, K.2    Nichols, K.3    Morris, G.P.4
  • 81
    • 0028174055 scopus 로고
    • Colocalization of gammaaminobutyrate and gastrin in the rat antrum: An immunocytochemical and in situ hybridization study
    • Davanger S, Hjelle OP, Babaie E et al. Colocalization of gammaaminobutyrate and gastrin in the rat antrum: an immunocytochemical and in situ hybridization study. Gastroenterology 1994; 107(1):137-48.
    • (1994) Gastroenterology , vol.107 , Issue.1 , pp. 137-148
    • Davanger, S.1    Hjelle, O.P.2    Babaie, E.3
  • 82
    • 0034618787 scopus 로고    scopus 로고
    • The expression of GABA(B1) and GABA(B2) receptor subunits in the CNS differs from that in peripheral tissues
    • Calver AR, Medhurst AD, Robbins MJ, et al. The expression of GABA(B1) and GABA(B2) receptor subunits in the CNS differs from that in peripheral tissues. Neuroscience 2000; 100(1): 155-70.
    • (2000) Neuroscience , vol.100 , Issue.1 , pp. 155-170
    • Calver, A.R.1    Medhurst, A.D.2    Robbins, M.J.3
  • 83
    • 73349089331 scopus 로고    scopus 로고
    • Presence of GABA(B) receptors forming heterodimers with GABA(B1) and GABA(B2) subunits in human lower esophageal sphincter
    • Torashima Y, Uezono Y, Kanaide M, et al. Presence of GABA(B) receptors forming heterodimers with GABA(B1) and GABA(B2) subunits in human lower esophageal sphincter. J Pharmacol Sci 2009; 111(3): 253-9.
    • (2009) J Pharmacol Sci , vol.111 , Issue.3 , pp. 253-259
    • Torashima, Y.1    Uezono, Y.2    Kanaide, M.3
  • 84
    • 7044253553 scopus 로고    scopus 로고
    • Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression
    • Sarkar S, Thompson DG, Woolf CJ, Hobson AR, Millane T, Aziz Q. Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression Am J Gastroenterol 2004; 99(10):1998-2006.
    • (2004) Am J Gastroenterol , vol.99 , Issue.10 , pp. 1998-2006
    • Sarkar, S.1    Thompson, D.G.2    Woolf, C.J.3    Hobson, A.R.4    Millane, T.5    Aziz, Q.6
  • 85
    • 84870462325 scopus 로고    scopus 로고
    • Pain management in patients with inflammatory bowel disease: Insights for the clinician
    • Srinath AI, Walter C, Newara MC, Szigethy EM. Pain management in patients with inflammatory bowel disease: insights for the clinician. Therap Adv Gastroenterol 2012; 5(5): 339-57.
    • (2012) Therap Adv Gastroenterol , vol.5 , Issue.5 , pp. 339-357
    • Srinath, A.I.1    Walter, C.2    Newara, M.C.3    Szigethy, E.M.4
  • 86
    • 84888639246 scopus 로고    scopus 로고
    • Stress and visceral pain: Focusing on irritable bowel syndrome
    • Fukudo S. Stress and visceral pain: focusing on irritable bowel syndrome. Pain 2013; 154 (Suppl 1): S63-70.
    • (2013) Pain , vol.154 , pp. S63-S70
    • Fukudo, S.1
  • 87
    • 0035840835 scopus 로고    scopus 로고
    • Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain
    • Holzer P. Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain. Eur J Pharmacol 2001; 429: 177-93.
    • (2001) Eur J Pharmacol , vol.429 , pp. 177-193
    • Holzer, P.1
  • 88
    • 70349907774 scopus 로고    scopus 로고
    • Visceral pain: The neurophysiological mechanism
    • Sengupta JN. Visceral pain: the neurophysiological mechanism. Handb Exp Pharmacol 2009; 194: 31-74.
    • (2009) Handb Exp Pharmacol , vol.194 , pp. 31-74
    • Sengupta, J.N.1
  • 89
    • 0033215989 scopus 로고    scopus 로고
    • GABAB receptors inhibit mechanosensitivity of primary afferent endings
    • Page AJ, Blackshaw LA. GABAB receptors inhibit mechanosensitivity of primary afferent endings. J Neurosci 1999; 19: 8597-602.
    • (1999) J Neurosci , vol.19 , pp. 8597-8602
    • Page, A.J.1    Blackshaw, L.A.2
  • 90
    • 0035925692 scopus 로고    scopus 로고
    • Presynaptic regulation of spinal cord tachykinin signaling via GABAB but not GABAA receptor activation
    • Riley RC, Trafton JA, Chi SI, Basbaum AL. Presynaptic regulation of spinal cord tachykinin signaling via GABAB but not GABAA receptor activation. Neuroscience 2001; 103: 725-37.
    • (2001) Neuroscience , vol.103 , pp. 725-737
    • Riley, R.C.1    Trafton, J.A.2    Chi, S.I.3    Basbaum, A.L.4
  • 91
    • 58549112362 scopus 로고    scopus 로고
    • The GABA(B) receptor agonist, baclofen, and the positive allosteric modulator, CGP7930, inhibit visceral painrelated responses to colorectal distension in rats
    • Brusberg M, Ravnefjord A, Martinsson R, Larsson H, Martinez V, Lindstrom E. The GABA(B) receptor agonist, baclofen, and the positive allosteric modulator, CGP7930, inhibit visceral painrelated responses to colorectal distension in rats. Neuropharmacology 2009; 56: 362-7.
    • (2009) Neuropharmacology , vol.56 , pp. 362-367
    • Brusberg, M.1    Ravnefjord, A.2    Martinsson, R.3    Larsson, H.4    Martinez, V.5    Lindstrom, E.6
  • 92
    • 79955980815 scopus 로고    scopus 로고
    • Oral baclofen reduces visceral pain-related pseudo-affective responses to colorectal distension in rats: Relation between plasma exposure and efficacy
    • Lindstrom E, Brusberg M, Ravnefjord A, et al. Oral baclofen reduces visceral pain-related pseudo-affective responses to colorectal distension in rats: relation between plasma exposure and efficacy. Scand J Gastroenterol 2011; 46: 652-62.
    • (2011) Scand J Gastroenterol , vol.46 , pp. 652-662
    • Lindstrom, E.1    Brusberg, M.2    Ravnefjord, A.3
  • 93
    • 79954588926 scopus 로고    scopus 로고
    • The analgesic effects of the GABAB receptor agonist, baclofen, in a rodent model of functional dyspepsia
    • Liu LS, Shenoy M, Pasricha PJ. The analgesic effects of the GABAB receptor agonist, baclofen, in a rodent model of functional dyspepsia. Neurogastroenterol Motil 2011; 23(356-61): e160-1.
    • (2011) Neurogastroenterol Motil , vol.23 , Issue.356-61 , pp. e160-e161
    • Liu, L.S.1    Shenoy, M.2    Pasricha, P.J.3
  • 94
    • 0032784216 scopus 로고    scopus 로고
    • The interaction of antinociceptive effects of morphine and GABA receptor agonists within the rat spinal cord
    • Hara K, Saito Y, Kirihara Y, Yamada Y, Sakura, S, Kosaka Y. The interaction of antinociceptive effects of morphine and GABA receptor agonists within the rat spinal cord. Anesth Analg 1999; 89:422-7.
    • (1999) Anesth Analg , vol.89 , pp. 422-427
    • Hara, K.1    Saito, Y.2    Kirihara, Y.3    Yamada, Y.4    Sakura, S.5    Kosaka, Y.6
  • 95
    • 0036890502 scopus 로고    scopus 로고
    • Effect of GABAB receptor agonist on distension-sensitive pelvic nerve afferent fibers innervating rat colon
    • Sengupta JN, Medda BK, Shaker R. Effect of GABAB receptor agonist on distension-sensitive pelvic nerve afferent fibers innervating rat colon. Am J Physiol Gastrointest Liver Physiol 2002; 283: 1343-51.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283 , pp. 1343-1351
    • Sengupta, J.N.1    Medda, B.K.2    Shaker, R.3
  • 96
    • 0027300596 scopus 로고
    • Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801
    • Yamamoto T, Walsh TL. Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801. Pain 1993; 54: 79-84.
    • (1993) Pain , vol.54 , pp. 79-84
    • Yamamoto, T.1    Walsh, T.L.2
  • 97
    • 9444271724 scopus 로고    scopus 로고
    • Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is reduced during central sensitization
    • Lin Q, Peng YB, Willis WD. Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is reduced during central sensitization. J Neurophysiol 1996; 76: 1005-14.
    • (1996) J Neurophysiol , vol.76 , pp. 1005-1014
    • Lin, Q.1    Peng, Y.B.2    Willis, W.D.3
  • 98
    • 0030580562 scopus 로고    scopus 로고
    • Loss of GABA immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion or recovery by adrenal medullary grafts
    • Ibuki T, Hama AT, Wang XT, Pappas GD, Sagen J. Loss of GABA immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion or recovery by adrenal medullary grafts. Neuroscience 1997; 76: 845-58.
    • (1997) Neuroscience , vol.76 , pp. 845-858
    • Ibuki, T.1    Hama, A.T.2    Wang, X.T.3    Pappas, G.D.4    Sagen, J.5
  • 99
    • 29744470942 scopus 로고    scopus 로고
    • Inhibition of mechanosensitivity in visceral primary afferents by GABAB receptors involves calcium and potassium channels
    • Page AJ, O’Donnell TA, Blackshaw LA. Inhibition of mechanosensitivity in visceral primary afferents by GABAB receptors involves calcium and potassium channels. Neuroscience 2006; 137(2): 627-36.
    • (2006) Neuroscience , vol.137 , Issue.2 , pp. 627-636
    • Page, A.J.1    O’Donnell, T.A.2    Blackshaw, L.A.3
  • 100
    • 84940460774 scopus 로고    scopus 로고
    • GABAB receptors inhibit low-voltage activated and high-voltage activated Ca(2+) channels in sensory neurons via distinct mechanisms
    • Huang D, Huang S, Peers C, Du X, Zhang H, Gamper N. GABAB receptors inhibit low-voltage activated and high-voltage activated Ca(2+) channels in sensory neurons via distinct mechanisms. Biochem Biophys Res Commun 2015; 465(2): 188-93.
    • (2015) Biochem Biophys Res Commun , vol.465 , Issue.2 , pp. 188-193
    • Huang, D.1    Huang, S.2    Peers, C.3    Du, X.4    Zhang, H.5    Gamper, N.6
  • 101
    • 0032970296 scopus 로고    scopus 로고
    • Substance P release in the dorsal horn assessed by receptor internalization:NMDA receptors counteract a tonic inhibition by GABAB receptors
    • Marvizon JC, Grady EF, Stefani E, Bunnett NW, Mayer EA. Substance P release in the dorsal horn assessed by receptor internalization:NMDA receptors counteract a tonic inhibition by GABAB receptors. Eur J Neurosci 1999; 11(2): 417-26.
    • (1999) Eur J Neurosci , vol.11 , Issue.2 , pp. 417-426
    • Marvizon, J.C.1    Grady, E.F.2    Stefani, E.3    Bunnett, N.W.4    Mayer, E.A.5
  • 102
    • 0036902236 scopus 로고    scopus 로고
    • Abdominal vagal afferent neurones: An important target for the treatment of gastrointestinal dysfunction
    • Andrews PL, Sanger GJ. Abdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunction. Curr Opin Pharmacol 2002; 2(6): 650-6.
    • (2002) Curr Opin Pharmacol , vol.2 , Issue.6 , pp. 650-656
    • Andrews, P.L.1    Sanger, G.J.2
  • 103
    • 84862804834 scopus 로고    scopus 로고
    • Irritable bowel syndrome: A review and update
    • Occhipinti K, Smith JW. Irritable bowel syndrome: a review and update. Clin Colon Rectal Surg 2012; 25(1): 46-52.
    • (2012) Clin Colon Rectal Surg , vol.25 , Issue.1 , pp. 46-52
    • Occhipinti, K.1    Smith, J.W.2
  • 104
    • 79953068140 scopus 로고    scopus 로고
    • Visceral hypersensitivity in irritable bowel syndrome
    • Kanazawa M, Hongo M, Fukudo S. Visceral hypersensitivity in irritable bowel syndrome. J Gastroenterol Hepatol 2011; 26(Suppl 3): 119-21.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 119-121
    • Kanazawa, M.1    Hongo, M.2    Fukudo, S.3
  • 105
    • 67849089070 scopus 로고    scopus 로고
    • A role for corticotropin-releasing factor in functional gastrointestinal disorders
    • Tache Y, Kiank C, Stengel A. A role for corticotropin-releasing factor in functional gastrointestinal disorders. Curr Gastroenterol Rep 2009; 11(4): 270-7.
    • (2009) Curr Gastroenterol Rep , vol.11 , Issue.4 , pp. 270-277
    • Tache, Y.1    Kiank, C.2    Stengel, A.3
  • 106
    • 20444422215 scopus 로고    scopus 로고
    • Peripheral injection of sauvagine prevents repeated colorectal distension-induced visceral pain in female rats
    • Million M, Maillot C, Adelson DA, et al. Peripheral injection of sauvagine prevents repeated colorectal distension-induced visceral pain in female rats. Peptides 2005; 26: 1188-95.
    • (2005) Peptides , vol.26 , pp. 1188-1195
    • Million, M.1    Maillot, C.2    Adelson, D.A.3
  • 107
    • 33749026656 scopus 로고    scopus 로고
    • Corticotropin-releasing factor induces rectal hypersensitivity after repetitive painful rectal distention in healthy humans
    • Nozu T, Kudaira M. Corticotropin-releasing factor induces rectal hypersensitivity after repetitive painful rectal distention in healthy humans. J Gastroenterol 2006; 41: 740-4.
    • (2006) J Gastroenterol , vol.41 , pp. 740-744
    • Nozu, T.1    Kudaira, M.2
  • 108
    • 84874753965 scopus 로고    scopus 로고
    • Pharmacokinetics, efficacy, and tolerability of a once-daily gastroretentive dosage form of gabapentin for the treatment of postherpetic neuralgia
    • Chen C, Han CH, Sweeney M, Cowles VE. Pharmacokinetics, efficacy, and tolerability of a once-daily gastroretentive dosage form of gabapentin for the treatment of postherpetic neuralgia. J Pharm Sci 2013; 102(4): 1155-64.
    • (2013) J Pharm Sci , vol.102 , Issue.4 , pp. 1155-1164
    • Chen, C.1    Han, C.H.2    Sweeney, M.3    Cowles, V.E.4
  • 109
    • 0032967201 scopus 로고    scopus 로고
    • Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats
    • Lu Y, Westlund KN. Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats. J Pharmacol Exp Ther 1999; 290:214-9.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 214-219
    • Lu, Y.1    Westlund, K.N.2
  • 110
    • 27744603267 scopus 로고    scopus 로고
    • Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoeapredominant irritable bowel syndrome
    • Lee KJ, Kim JH, Cho SW. Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoeapredominant irritable bowel syndrome. Aliment Pharmacol Ther 2005; 22: 981-8.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 981-988
    • Lee, K.J.1    Kim, J.H.2    Cho, S.W.3
  • 111
    • 80052031321 scopus 로고    scopus 로고
    • The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity
    • O’Mahony SM, Coelho AM, Fitzgerald P, et al. The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity. Eur J Pharmacol 2011; 667: 169-74.
    • (2011) Eur J Pharmacol , vol.667 , pp. 169-174
    • O’Mahony, S.M.1    Coelho, A.M.2    Fitzgerald, P.3
  • 112
    • 52949083537 scopus 로고    scopus 로고
    • Effects of pregabalin on visceral pain responses and colonic compliance in rats
    • Ravnefjord A, Brusberg M, Larsson H, Lindstrom E, Martinez V. Effects of pregabalin on visceral pain responses and colonic compliance in rats. Br J Pharmacol 2008; 155(3): 407-16.
    • (2008) Br J Pharmacol , vol.155 , Issue.3 , pp. 407-416
    • Ravnefjord, A.1    Brusberg, M.2    Larsson, H.3    Lindstrom, E.4    Martinez, V.5
  • 113
    • 0036707535 scopus 로고    scopus 로고
    • Pregabalin (CI-1008) inhibits the trinitrobenzene sulfonic acid-induced chronic colonic allodynia in the rat
    • Diop L, Raymond F, Fargeau H, Petoux F, Chovet M, Doherty AM. Pregabalin (CI-1008) inhibits the trinitrobenzene sulfonic acid-induced chronic colonic allodynia in the rat. J Pharmacol Exp Ther 2002; 302(3): 1013-22.
    • (2002) J Pharmacol Exp Ther , vol.302 , Issue.3 , pp. 1013-1022
    • Diop, L.1    Raymond, F.2    Fargeau, H.3    Petoux, F.4    Chovet, M.5    Doherty, A.M.6
  • 114
    • 34948851724 scopus 로고    scopus 로고
    • Pregabalin decreases visceral pain and prevents spinal neuronal activation in rats
    • Million M, Wang L, Adelson DW, Roman F, Diop L, Tache Y. Pregabalin decreases visceral pain and prevents spinal neuronal activation in rats. Gut 2007; 56: 1482-4.
    • (2007) Gut , vol.56 , pp. 1482-1484
    • Million, M.1    Wang, L.2    Adelson, D.W.3    Roman, F.4    Diop, L.5    Tache, Y.6
  • 115
    • 34548127061 scopus 로고    scopus 로고
    • Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome
    • Houghton LA, Fell C, Whorwell PJ, Jones I, Sudworth DP, Gale JD. Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome. Gut 2007; 56(9): 1218-25.
    • (2007) Gut , vol.56 , Issue.9 , pp. 1218-1225
    • Houghton, L.A.1    Fell, C.2    Whorwell, P.J.3    Jones, I.4    Sudworth, D.P.5    Gale, J.D.6
  • 117
    • 84893693732 scopus 로고    scopus 로고
    • Pilot trial: Pregabalin on colonic sensorimotor functions in irritable bowel syndrome
    • Iturrino J, Camilleri M, Busciglio I, Burton D, Zinsmeister AR. Pilot trial: pregabalin on colonic sensorimotor functions in irritable bowel syndrome. Dig Liver Dis 2014; 46(2): 113-8.
    • (2014) Dig Liver Dis , vol.46 , Issue.2 , pp. 113-118
    • Iturrino, J.1    Camilleri, M.2    Busciglio, I.3    Burton, D.4    Zinsmeister, A.R.5
  • 118
    • 84975248871 scopus 로고    scopus 로고
    • Drugging the undruggable: Gabapentin, pregabalin and calcium channel α2δ subunit
    • Offord J, Isom LL. Drugging the undruggable: gabapentin, pregabalin and calcium channel α2δ subunit. Crit Rev Biochem Mol Biol 2015, 51(4): 246-56.
    • (2015) Crit Rev Biochem Mol Biol , vol.51 , Issue.4 , pp. 246-256
    • Offord, J.1    Isom, L.L.2
  • 120
  • 121
    • 0017813995 scopus 로고
    • GABAergic terminals are presynaptic to primary afferent terminals in the substantia gelatinosa of the rat spinal cord
    • Barber RP, Vaughn JE, Saito K, McLaughlin BJ, Roberts E. GABAergic terminals are presynaptic to primary afferent terminals in the substantia gelatinosa of the rat spinal cord. Brain Res 1978; 141: 35-55.
    • (1978) Brain Res , vol.141 , pp. 35-55
    • Barber, R.P.1    Vaughn, J.E.2    Saito, K.3    McLaughlin, B.J.4    Roberts, E.5
  • 122
    • 0029549990 scopus 로고
    • Opioid antinociception in a rat model of visceral pain: Systemic versus local drug administration
    • Craft RM, Henley SR, Haaseth RC, Hruby VJ, Porreca F. Opioid antinociception in a rat model of visceral pain: systemic versus local drug administration. J Pharmacol Exp Ther 1995; 275: 1535-42.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1535-1542
    • Craft, R.M.1    Henley, S.R.2    Haaseth, R.C.3    Hruby, V.J.4    Porreca, F.5
  • 123
    • 0035128610 scopus 로고    scopus 로고
    • Peripheral and preemptive opioid antinociception in a mouse visceral pain model
    • Reichert JA, Daughters RS, Rivard R, Simone DA. Peripheral and preemptive opioid antinociception in a mouse visceral pain model. Pain 2001; 89: 221-7.
    • (2001) Pain , vol.89 , pp. 221-227
    • Reichert, J.A.1    Daughters, R.S.2    Rivard, R.3    Simone, D.A.4
  • 124
    • 0026688363 scopus 로고
    • Vagal afferent modulation of nociception
    • Randich A, Gebhart GF. Vagal afferent modulation of nociception. Brain Res Brain Res Rev 1992; 17(2): 77-99.
    • (1992) Brain Res Brain Res Rev , vol.17 , Issue.2 , pp. 77-99
    • Randich, A.1    Gebhart, G.F.2
  • 125
    • 0031470828 scopus 로고    scopus 로고
    • How opioids inhibit GABA-mediated neurotransmission
    • Vaughan CW, Ingram SL, Connor MA, Christie MJ. How opioids inhibit GABA-mediated neurotransmission. Nature 1997; 390(6660): 611-4.
    • (1997) Nature , vol.390 , Issue.6660 , pp. 611-614
    • Vaughan, C.W.1    Ingram, S.L.2    Connor, M.A.3    Christie, M.J.4
  • 126
    • 0033672574 scopus 로고    scopus 로고
    • Stress and neuroimmune regulation of gut mucosal function
    • Santos J, Perdue MH. Stress and neuroimmune regulation of gut mucosal function. Gut 2000; 47(Suppl4): 49-51.
    • (2000) Gut , vol.47 , pp. 49-51
    • Santos, J.1    Perdue, M.H.2
  • 127
    • 43049085167 scopus 로고    scopus 로고
    • Neuroimmune interactions in inflammatory bowel disease and irritable bowel syndrome: Future therapeutic targets
    • Kraneveld AD, Rijnierse A, Nijkamp FP, Garssen J. Neuroimmune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets. Eur J Pharmacol 2008; 585(2-3): 361-74.
    • (2008) Eur J Pharmacol , vol.585 , Issue.2-3 , pp. 361-374
    • Kraneveld, A.D.1    Rijnierse, A.2    Nijkamp, F.P.3    Garssen, J.4
  • 128
    • 84879198473 scopus 로고    scopus 로고
    • GABA is an effective immunomodulatory molecule
    • Jin Z, Mendu SK, Birnir B. GABA is an effective immunomodulatory molecule. Amino Acids 2013; 45(1): 87-94.
    • (2013) Amino Acids , vol.45 , Issue.1 , pp. 87-94
    • Jin, Z.1    Mendu, S.K.2    Birnir, B.3
  • 129
    • 56349109485 scopus 로고    scopus 로고
    • GABA, a natural immunomodulator of T lymphocytes
    • Bjurstom H, Wang J, Ericsson I, et al. GABA, a natural immunomodulator of T lymphocytes. J Neuroimmunol 2008; 205(1-2): 44-50.
    • (2008) J Neuroimmunol , vol.205 , Issue.1-2 , pp. 44-50
    • Bjurstom, H.1    Wang, J.2    Ericsson, I.3
  • 130
    • 77249104532 scopus 로고    scopus 로고
    • Inhibitory role for GABA in autoimmune inflammation
    • Bhat R, Axtell R, Mitra A, et al. Inhibitory role for GABA in autoimmune inflammation. Proc Natl Acad Sci USA 2010; 107(6):2580-5.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.6 , pp. 2580-2585
    • Bhat, R.1    Axtell, R.2    Mitra, A.3
  • 131
    • 80051498172 scopus 로고    scopus 로고
    • Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis
    • Tian J, Yong J, Dang H, Kaufman DL. Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis. Autoimmunity 2011; 44(6): 465-70.
    • (2011) Autoimmunity , vol.44 , Issue.6 , pp. 465-470
    • Tian, J.1    Yong, J.2    Dang, H.3    Kaufman, D.L.4
  • 132
    • 0029670886 scopus 로고    scopus 로고
    • gamma-Aminobutyric acid stimulates electrolyte transport in the guinea pig ileum in vitro
    • MacNaughton WK, Pineau BC, Krantis A. gamma-Aminobutyric acid stimulates electrolyte transport in the guinea pig ileum in vitro. Gastroenterology 1996; 110: 498-507.
    • (1996) Gastroenterology , vol.110 , pp. 498-507
    • MacNaughton, W.K.1    Pineau, B.C.2    Krantis, A.3
  • 133
    • 84865132169 scopus 로고    scopus 로고
    • A novel role of intestine epithelial GABAergic signaling in regulating intestinal fluid secretion
    • Li Y, Xiang YY, Lu WY, Liu C, Li J. A novel role of intestine epithelial GABAergic signaling in regulating intestinal fluid secretion. Am J Physiol Gastrointest Liver Physiol 2012; 303(4): 453-60.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303 , Issue.4 , pp. 453-460
    • Li, Y.1    Xiang, Y.Y.2    Lu, W.Y.3    Liu, C.4    Li, J.5
  • 135
    • 84873616370 scopus 로고    scopus 로고
    • CD4(+) T-cell subsets in intestinal inflammation
    • Shale M, Schiering C, Powrie F. CD4(+) T-cell subsets in intestinal inflammation. Immunol Rev 2013; 252(1): 164-82.
    • (2013) Immunol Rev , vol.252 , Issue.1 , pp. 164-182
    • Shale, M.1    Schiering, C.2    Powrie, F.3
  • 137
    • 80053078763 scopus 로고    scopus 로고
    • Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice
    • Tian J, Dang HN, Yong J, Chui WS, Dizon MP, Yaw CK, Kaufman DL. Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. PLoS One 2011; 6(9): e25338.
    • (2011) PLoS One , vol.6 , Issue.9
    • Tian, J.1    Dang, H.N.2    Yong, J.3    Chui, W.S.4    Dizon, M.P.5    Yaw, C.K.6    Kaufman, D.L.7
  • 138
    • 79960996764 scopus 로고    scopus 로고
    • GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes
    • Soltani N, Qiu H, Aleksic M, et al. GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes. Proc Natl Acad Sci USA 2011; 108: 11692-7.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 11692-11697
    • Soltani, N.1    Qiu, H.2    Aleksic, M.3
  • 140
    • 25444470762 scopus 로고    scopus 로고
    • Psychological stress in IBD: New insights into pathogenic and therapeutic implications
    • Mawdsley JE, Rampton DS. Psychological stress in IBD: new insights into pathogenic and therapeutic implications. Gut 2005; 54(10): 1481-91.
    • (2005) Gut , vol.54 , Issue.10 , pp. 1481-1491
    • Mawdsley, J.E.1    Rampton, D.S.2
  • 141
    • 0036839613 scopus 로고    scopus 로고
    • Corticotropinreleasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice
    • Agelaki S, Tsatsanis C, Gravanis A, Margioris AN. Corticotropinreleasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice. Infect Immun 2002; 70: 6068-74.
    • (2002) Infect Immun , vol.70 , pp. 6068-6074
    • Agelaki, S.1    Tsatsanis, C.2    Gravanis, A.3    Margioris, A.N.4
  • 143
    • 84931846557 scopus 로고    scopus 로고
    • New molecules as drug candidates for the treatment of upper and lower GI tract ulcers
    • Szabo S, Tolstanova G. New molecules as drug candidates for the treatment of upper and lower GI tract ulcers. Curr Pharm Des 2015; 21(21): 2993-3001.
    • (2015) Curr Pharm Des , vol.21 , Issue.21 , pp. 2993-3001
    • Szabo, S.1    Tolstanova, G.2


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