Physiological comparability of the harmonized INFOGEST in vitro digestion method to in vivo pig digestion

Food Research International

Volumn 102, Issue , 2017, Pages 567-574

  Egger, Lotti ^a   Schlegel, Patrick ^a   Baumann, Christian ^a   Stoffers, Helena ^a   Guggisberg, Dominik ^a   Brügger, Cédric ^a   Dürr, Desirée ^a   Stoll, Peter ^a   Vergères, Guy ^a   Portmann, Reto ^a  

^a AGROSCOPE   (Switzerland)

Author keywords

Dairy proteins; Harmonized IVD protocol; In vitro in vivo digestion; Mass spectrometry; Peptides

Indexed keywords

AMINO ACIDS; DAIRIES; DRUG PRODUCTS; ELECTROPHORESIS; ENZYMES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; PEPTIDES; PHYSIOLOGY;

GEL ELECTROPHORESIS; HARMONIZED PROTOCOL; IN-VITRO DIGESTIONS; IN-VIVO; LABORATORY STUDIES; PRINCIPLE COMPONENT ANALYSIS; PROTEIN HYDROLYSIS; SALT CONCENTRATION;

HYDROLYSIS;

MILK PROTEIN;

ANIMAL; COMPARATIVE STUDY; DIGESTION; DUODENUM; HUMAN; HYDROLYSIS; IN VITRO STUDY; INTESTINE MUCOSA; JEJUNUM; METABOLISM; MILK; PHYSIOLOGY; PIG; PRESERVED FOOD; REPRODUCIBILITY; STOMACH MUCOSA;

ANIMALS; DIGESTION; DUODENUM; FOOD, PRESERVED; GASTRIC MUCOSA; HUMANS; HYDROLYSIS; IN VITRO TECHNIQUES; INTESTINAL MUCOSA; JEJUNUM; MILK; MILK PROTEINS; REPRODUCIBILITY OF RESULTS; SWINE;

EID: 85029669535     PISSN: 09639969     EISSN: 18737145     Source Type: Journal    
DOI: 10.1016/j.foodres.2017.09.047     Document Type: Article

References (29)

1. (Producer), & INFOGEST (Director), Static In Vitro Digestion Method for Food. https://www.youtube.com/watch?v=LNSIIb-OJGc, 2014.
2. Barbe, F., Menard, O., Le Gouar, Y., Buffiere, C., Famelart, M.H., Laroche, B., Dupont, D., Acid and rennet gels exhibit strong differences in the kinetics of milk protein digestion and amino acid bioavailability. Food Chemistry 143 (2014), 1–8, 10.1016/j.foodchem.2013.07.100.
3. Bidlingmeyer, B.A., Cohen, S.A., Tarvin, T.L., Rapid analysis of amino acids using pre-column derivatization. Journal of Chromatography 336:1 (1984), 93–104.
4. Cicero, A.F.G., Fogacci, F., Colletti, A., Potential role of bioactive peptides in prevention and treatment of chronic diseases: a narrative review. British Journal of Pharmacology 174:11 (2017), 1378–1394.
5. Clemente, A., Enzymatic protein hydrolysates in human nutrition. Trends in Food Science and Technology 11:7 (2000), 254–262, 10.1016/S0924-2244(01)00007-3.
6. Egger, L., Ménard, O., Update on bioactive peptides after milk and cheese digestion. Current Opinion in Food Science 14:Supplement C (2017), 116–121.
7. Egger, L., Ménard, O., Delgado-Andrade, C., Alvito, P., Assunção, R., Balance, S., Portmann, R., The harmonized INFOGEST in vitro digestion method: From knowledge to action. Food Research International 88 (2016), 217–225, 10.1016/j.foodres.2015.12.006.
8. Egger, L., Schlegel, P., Baumann, C., Stoffers, H., Guggisberg, D., Brügger, C., Portmann, R., Mass spectrometry data of in vitro and in vivo pig digestion of skim milk powder. Food Research International, 2017 (Data in Brief, submitted).
9. Guerin, S., Ramonet, Y., LeCloarec, J., Meunier-Salaün, M.C., Bourguet, P., Malbert, C.H., Changes in intragastric meal distribution are better predictors of gastric emptying rate in conscious pigs than are meal viscosity or dietary fibre concentration. British Journal of Nutrition 85:3 (2007), 343–350, 10.1079/BJN2000271.
10. Hur, S.J., Lim, B.O., Decker, E.A., McClements, D.J., In vitro human digestion models for food applications. Food Chemistry 125:1 (2011), 1–12, 10.1016/j.foodchem.2010.08.036.
11. Jolliffe, I., Principal component analysis and factor analysis. Principal Component Analysis, 2002, Springer New York, New York, NY, 150–166.
12. Kang, D., Gho, Y., Suh, M., Kang, C., Highly sensitive and fast protein detection with Coomassie brilliant blue in sodium dodecyl sulfate - polyacrylamide gel electrophoresis. Bulletin of the Korean Chemical Society, 2, 2002.
13. Kiela, P.R., Ghishan, F.K., Physiology of intestinal absorption and secretion. Best Practice & Research Clinical Gastroenterology 30:2 (2016), 145–159, 10.1016/j.bpg.2016.02.007.
14. Kopf-Bolanz, K.A., Schwander, F., Gijs, M., Vergeres, G., Portmann, R., Egger, L., Validation of an in vitro digestive system for studying macronutrient decomposition in humans. The Journal of Nutrition 142:2 (2012), 245–250, 10.3945/jn.111.148635.
15. Laplace, J.P., The transit of digesta in the different parts of the digestive tract of the pig. Progress in Clinical and Biological Research 77 (1981), 847–872.
16. Létourneau-Montminy, M.P., Narcy, A., Magnin, M., Sauvant, D., Bernier, J.F., Pomar, C., Jondreville, C., Effect of reduced dietary calcium concentration and phytase supplementation on calcium and phosphorus utilization in weanling pigs with modified mineral status. [article]. Journal of Animal Science 88:5 (2010), 1706–1717, 10.2527/jas.2008-1615.
17. López-Fandiño, R., Otte, J., van Camp, J., Physiological, chemical and technological aspects of milk-protein-derived peptides with antihypertensive and ACE-inhibitory activity. International Dairy Journal 16:11 (2006), 1277–1293, 10.1016/j.idairyj.2006.06.004.
18. Low, A.G., Pittman, R.J., Elliott, R.J., Gastric emptying of barley-soya-bean diets in the pig: Effects of feeding level, supplementary maize oil, sucrose or cellulose, and water intake. British Journal of Nutrition 54:2 (2007), 437–447, 10.1079/BJN19850129.
19. Mandalari, G., Adel-Patient, K., Barkholt, V., Baro, C., Bennett, L., Bublin, M., Mills, E.N., In vitro digestibility of beta-casein and beta-lactoglobulin under simulated human gastric and duodenal conditions: A multi-laboratory evaluation. Regulatory Toxicology and Pharmacology 55:3 (2009), 372–381, 10.1016/j.yrtph.2009.08.010.
20. McClements, D.J., Li, Y., Review of in vitro digestion models for rapid screening of emulsion-based systems. Food & Function 1:1 (2010), 32–59, 10.1039/c0fo00111b.
21. Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., Brodkorb, A., A standardised static in vitro digestion method suitable for food - an international consensus. Food & Function 5:6 (2014), 1113–1124, 10.1039/c3fo60702j.
22. Nongonierma, A.B., FitzGerald, R.J., Bioactive properties of milk proteins in humans: A review. [review]. Peptides 73 (2015), 20–34.
23. Picariello, G., Ferranti, P., Fierro, O., Mamone, G., Caira, S., Di Luccia, A., Addeo, F., Peptides surviving the simulated gastrointestinal digestion of milk proteins: Biological and toxicological implications. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 878:3–4 (2010), 295–308, 10.1016/j.jchromb.2009.11.033.
24. Sanchón, J., Fernández-Tomé, S., Miralles, B., Hernández-Ledesma, B., Tomé, D., Gaudichon, C., Recio, I., Protein degradation and peptide release from milk proteins in human jejunum. Comparison with in vitro gastrointestinal simulation. Food Chemistry 239 (2018), 486–494, 10.1016/j.foodchem.2017.06.134.
25. Sciascia, Q., Daş, G., Metges, C.C., REVIEW: The pig as a model for humans: Effects of nutritional factors on intestinal function and health1. Journal of Animal Science 94:supplement3 (2016), 441–452, 10.2527/jas.2015-9788.
26. Shimizu, M., Food-derived peptides and intestinal functions. BioFactors 21:1–4 (2004), 43–47, 10.1002/biof.552210109.
27. Versantvoort, C.H., Oomen, A.G., Van de Kamp, E., Rompelberg, C.J., Sips, A.J., Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food. Food and Chemical Toxicology 43:1 (2005), 31–40, 10.1016/j.fct.2004.08.007.
28. Wickham, M., Faulks, R., Mills, C., In vitro digestion methods for assessing the effect of food structure on allergen breakdown. Molecular Nutrition & Food Research 53:8 (2009), 952–958, 10.1002/mnfr.200800193.
29. Ye, A., Cui, J., Dalgleish, D., Singh, H., Formation of a structured clot during the gastric digestion of milk: Impact on the rate of protein hydrolysis. Food Hydrocolloids 52 (2016), 478–486, 10.1016/j.foodhyd.2015.07.023.