Validation of an in vitro digestive system for studying macronutrient decomposition in humans

Journal of Nutrition

Volumn 142, Issue 2, 2012, Pages 245-250

  Kopf Bolanz, Katrin A ^a   Schwander, Flurina ^a   Gijs, Martin ^b   Vergéres, Guy ^a   Portmann, Reto ^a   Egger, Lotti ^a  

^a AGROSCOPE LIEBEFELD POSIEUX RESEARCH STATION ALP   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PEPTIDES AND PROTEINS;

ARTICLE; CONTROLLED STUDY; COW; DECOMPOSITION; DIGESTION; DIGESTIVE SYSTEM; FOOD COMPOSITION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; LIQUID CHROMATOGRAPHY; MACRONUTRIENT; MASS SPECTROMETRY; MILK; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DIGESTION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FATS; HUMANS; MASS SPECTROMETRY; MILK; MODELS, BIOLOGICAL; NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PROTEINS; REPRODUCIBILITY OF RESULTS;

BOVINAE;

EID: 84858237139     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.148635     Document Type: Article

References (36)

1. Glahn RP, Lee OA, Yeung A, Goldman MI, Miller DD. Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model. J Nutr. 1998;128:1555-61.
2. O'Sullivan L, Jiwan MA, Daly T, O'Brien NM, Aherne SA. Bioaccessibility, uptake, and transport of carotenoids from peppers (Capsicum spp.) using the coupled in vitro digestion and human intestinal Caco-2 cell model. J Agric Food Chem. 2010;58:5374-9.
3. Sabboh-Jourdan H, Valla F, Epriliati I, Gidley MJ. Organic acid bioavailability from banana and sweet potato using an in vitro digestion and Caco-2 cell model. Eur J Nutr. 2011;50:31-40.
4. Kanwar JR, Kanwar RK. Gut health immunomodulatory and antiinflammatory functions of gut enzyme digested high protein micronutrient dietary supplement-Enprocal. BMC Immunol. 2009;10:7.
5. Haug A, Hostmark AT, Harstad OM. Bovine milk in human nutrition: a review. Lipids Health Dis. 2007;6:25.
6. Daniel H. Molecular and integrative physiology of intestinal peptide transport. Annu Rev Physiol. 2004;66:361-84.
7. Michalski MC, Cariou R, Michel F, Garnier C. Native vs. damaged milk fat globules: membrane properties affect the viscoelasticity of milk gels. J Dairy Sci. 2002;85:2451-61.
8. Benzonana G, Desnuelle P. [Kinetic study of the action of pancreatic lipase on emulsified triglycerides. Enzymology assay in heterogeneous medium]. Biochim Biophys Acta. 1965;105:121-36.
9. Mathias PM, Harries JT, Peters TJ, Muller DP. Studies on the in vivo absorption of micellar solutions of tocopherol and tocopheryl acetate in the rat: demonstration and partial characterization of a mucosal esterase localized to the endoplasmic reticulum of the enterocyte. J Lipid Res. 1981;22:829-37.
10. Mattson FH, Beck LW. The specificity of pancreatic lipase for the primary hydroxyl groups of glycerides. J Biol Chem. 1956;219: 735-40.
11. Mu H, Hoy CE. The digestion of dietary triacylglycerols. Prog Lipid Res. 2004;43:105-33.
12. Geigy Scientific Tables. Geigy scientific tables. Basle: Ciba-Geigy Limited; 1981.
13. Jakob M. Normalwerte pocket. 5th ed. Grü nwald: Börm Bruckmeier Verlag; 2008.
14. Versantvoort CH, Oomen AG, Van de Kamp E, Rompelberg CJ, Sips AJ. Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food. Food Chem Toxicol. 2005;43:31-40.
15. Kang D, Gho YS, Suh M, Kang C. Highly sensitive and fast protein detection with coomassie brilliant blue in sodium dodecyl sulfatepolyacrylamide gel electrophoresis. Bull Korean Chem Soc. 2002;23: 1511-2.
16. Church FC, Swaisgood HE, Porter DH, Catignani GL. Spectrophotometric assay using o-phthaldialdehyde for determination of proteolysis in milk and isolated milk proteins. J Dairy Sci. 1983;66:1219-27.
17. Chang JY, Knecht R. Direct analysis of the disulfide content of proteins: methods for monitoring the stability and refolding process of cystinecontaining proteins. Anal Biochem. 1991;197:52-8.
18. Yust MM, Pedroche J, Giron-Calle J, Vioque J, Millan F, Alaiz M. Determination of tryptophan by high-performance liquid chromatography of alkaline hydrolysates with spectrophotometric detection. Food Chem. 2004;85:317-20.
19. Dejong C, Badings HT. Determination of free fatty-acids in milk and cheese: procedures for extraction, clean up, and capillary gas-chromatographic analysis. HRC-J High Res Chrom. 1990;13:94-8.
20. Davies CS. Statistical methods for the analysis of repeated measurements. New York: Springer; 2002.
21. Mattson FH, Benedict JH, Beck LW. Composition of intestinal lumen lipides following the feeding of triglycerides, partial glycerides or free fatty acids. J Nutr. 1954;52:575-80.
22. Singh J, Dartois A, Kaur L. Starch digestibility in food matrix: a review. Trends Food Sci Technol. 2010;21:168-80.
23. Cicero AF, Gerocarni B, Laghi L, Borghi C. Blood pressure lowering effect of lactotripeptides assumed as functional foods: a meta-analysis of current available clinical trials. J Hum Hypertens. 2011;25:425-36.
24. Davis LM, Martinez I, Walter J, Hutkins R. A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol. 2010;144:285-92.
25. Hennessy AA, Ross RP, Devery R, Stanton C. The health promoting properties of the conjugated isomers of alpha-linolenic acid. Lipids. 2011;46:105-19.
26. Otani H, Monnai M. Inhibition of proliferative responses of mouse spleen lymphocytes by bovine milk kappa-casein digests. Food Agric Immunol. 1993;5:219-29.
27. Torres-Escribano S, Denis S, Blanquet-Diot S, Calatayud M, Barrios L, Velez D, Alric M, Montoro R. Comparison of a static and a dynamic in vitro model to estimate the bioaccessibility of As, Cd, Pb and Hg from food reference materials Fucus sp. (IAEA-140/TM) and Lobster hepatopancreas (TORT-2). Sci Total Environ. 2011;409:604-11.
28. Kong F, Singh RP. A human gastric simulator (HGS) to study food digestion in human stomach. J Food Sci. 2010;75:E627-35.
29. Tharakan A, Norton IT, Fryer PJ, Bakalis S. Mass transfer and nutrient absorption in a simulated model of small intestine. J Food Sci. 2010;75: E339-46.
30. Mandalari G, Adel-Patient K, Barkholt V, Baro C, Bennett L, Bublin M, Gaier S, Graser G, Ladics GS, Mierzejewska D, et al. In vitro digestibility of beta-casein and beta-lactoglobulin under simulated human gastric and duodenal conditions: a multi-laboratory evaluation. Regul Toxicol Pharmacol. 2009;55:372-81.
31. Gass J, Vora H, Hofmann AF, Gray GM, Khosla C. Enhancement of dietary protein digestion by conjugated bile acids. Gastroenterology. 2007;133:16-23.
32. Imura K, Okada A. Amino acid metabolism in pediatric patients. Nutrition. 1998;14:143-8.
33. Iqbal J, Hussain MM. Intestinal lipid absorption. Am J Physiol Endocrinol Metab. 2009;296:E1183-94.
34. Armand M, Pasquier B, Andre M, Borel P, Senft M, Peyrot J, Salducci J, Portugal H, Jaussan V, Lairon D. Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract. Am J Clin Nutr. 1999;70:1096-106.
35. Barbano DM, Sherbon JW. Stereospecific analysis of high melting triglycerides of bovine milk fat and their biosynthetic origin. J Dairy Sci. 1975;58:1-8.
36. Mattson FH, Volpenhein RA. The digestion and absorption of triglycerides. J Biol Chem. 1964;239:2772-7.