Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Rivera Vargas, Thaiz ^a,b   Cai, Zhijian ^c   Shen, Yingying ^c   Dosset, Magalie ^a,b,d   Benoit Lizon, Isis ^a,b   Martin, Tiffany ^a,b   Roussey, Aurélie ^a,b   Flavell, Richard A ^e   Ghiringhelli, François ^a,b,f   Apetoh, Lionel ^a,b,f  

^a Institut Médical de Génétique et d Immunologie   (France)

^b UNIVERSITÉ BOURGOGNE FRANCHE COMTÉ   (France)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ETABLISSEMENT FRANÇAIS DU SANG   (France)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f CENTRE GEORGES FRANÇOIS LECLERC   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY RELATED PROTEIN 3; AUTOPHAGY RELATED PROTEIN 5; INTERLEUKIN 9; SEQUESTOSOME 1; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG; ATG3 PROTEIN, MOUSE; ATG5 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN; ONCOPROTEIN; PROTO-ONCOGENE PROTEIN SPI-1; TRANSACTIVATOR PROTEIN; UBIQUITIN CONJUGATING ENZYME;

CANCER; CATABOLISM; CELLS AND CELL COMPONENTS; DEGRADATION; DIFFERENTIATION; HOMEOSTASIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER IMMUNOTHERAPY; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TH9 CELL; TUMOR GROWTH; UBIQUITINATION; ANIMAL; HELPER CELL; IMMUNOLOGY; IMMUNOTHERAPY; LYMPHOPOIESIS; METABOLISM; NEOPLASM; T LYMPHOCYTE SUBPOPULATION;

MUS;

ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 5; AUTOPHAGY-RELATED PROTEINS; CELL DIFFERENTIATION; IMMUNOTHERAPY; INTERLEUKIN-9; LYMPHOPOIESIS; MICE; NEOPLASMS; PROTO-ONCOGENE PROTEINS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TRANS-ACTIVATORS; UBIQUITIN-CONJUGATING ENZYMES;

EID: 85029503224     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00468-w     Document Type: Article

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