-
1
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann, T.R., Cherwinski, H., Bond, M.W., Giedlin, M.A. & Coffman, R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136, 2348-2357 (1986).
-
(1986)
J. Immunol.
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
2
-
-
61949463911
-
IL-17 and Th17 cells
-
Korn, T., Bettelli, E., Oukka, M. & Kuchroo, V.K. IL-17 and Th17 Cells. Annu. Rev. Immunol. 27, 485-517 (2009).
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
3
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty, S. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621-663 (2011).
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
4
-
-
77954141914
-
FOXP3+ regulatory T cells in the human immune system
-
Sakaguchi, S., Miyara, M., Costantino, C.M. & Hafler, D.A. FOXP3+ regulatory T cells in the human immune system. Nat. Rev. Immunol. 10, 490-500 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 490-500
-
-
Sakaguchi, S.1
Miyara, M.2
Costantino, C.M.3
Hafler, D.A.4
-
5
-
-
56349093347
-
IL-4 inhibits TGF-induced Foxp3+ T cells and, together with TGF-, generates IL-9+IL-10+Foxp3- effector T cells
-
Dardalhon, V. et al. IL-4 inhibits TGF-induced Foxp3+ T cells and, together with TGF-, generates IL-9+IL-10+Foxp3- effector T cells. Nat. Immunol. 9, 1347-1355 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1347-1355
-
-
Dardalhon, V.1
-
6
-
-
56349154943
-
Transforming growth factor- 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen, M. et al. Transforming growth factor- 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 9, 1341-1346 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
-
7
-
-
73349109145
-
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
-
Jäger, A., Dardalhon, V., Sobel, R.A., Bettelli, E. & Kuchroo, V.K. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 183, 7169-7177 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 7169-7177
-
-
Jäger, A.1
Dardalhon, V.2
Sobel, R.A.3
Bettelli, E.4
Kuchroo, V.K.5
-
8
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt, V. et al. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 33, 192-202 (2010).
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
-
9
-
-
77952584843
-
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
-
Chang, H.C. et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol. 11, 527-534 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 527-534
-
-
Chang, H.C.1
-
10
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
Rengarajan, J. et al. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J. Exp. Med. 195, 1003-1012 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1003-1012
-
-
Rengarajan, J.1
-
11
-
-
0025246676
-
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
-
Klemsz, M.J., McKercher, S.R., Celada, A., Van Beveren, C. & Maki, R.A. The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell 61, 113-124 (1990).
-
(1990)
Cell
, vol.61
, pp. 113-124
-
-
Klemsz, M.J.1
McKercher, S.R.2
Celada, A.3
Van Beveren, C.4
Maki, R.A.5
-
12
-
-
84864648969
-
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells
-
Purwar, R. et al. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat. Med. 18, 1248-1253 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 1248-1253
-
-
Purwar, R.1
-
13
-
-
84868611628
-
Th9 cells promote antitumor immune response in vivo
-
Lu, Y. et al. Th9 cells promote antitumor immune responses in vivo. J. Clin. Invest. 122, 4160-4171 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4160-4171
-
-
Lu, Y.1
-
14
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1-dependent adaptive immunity against tumors
-
Ghiringhelli, F. et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1-dependent adaptive immunity against tumors. Nat. Med. 15, 1170-1178 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
-
15
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung, Y. et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30, 576-587 (2009).
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
-
16
-
-
84857806891
-
The tick salivary protein sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma
-
Horka, H. et al. The tick salivary protein sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma. J. Immunol. 188, 2669-2676 (2012).
-
(2012)
J. Immunol.
, vol.188
, pp. 2669-2676
-
-
Horka, H.1
-
17
-
-
0030741433
-
Multistage regulation of Th1-type immune responses by the transcription factor IRF-1
-
Taki, S. et al. Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 6, 673-679 (1997).
-
(1997)
Immunity
, vol.6
, pp. 673-679
-
-
Taki, S.1
-
18
-
-
0030747793
-
Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo
-
Lohoff, M. et al. Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. Immunity 6, 681-689 (1997).
-
(1997)
Immunity
, vol.6
, pp. 681-689
-
-
Lohoff, M.1
-
19
-
-
70349199467
-
Anthocyanins from black soybean seed coats preferentially inhibit TNF-alpha-mediated induction of VCAM-1 over ICAM-1 through the regulation of GATAs and IRF-1
-
Nizamutdinova, I.T. et al. Anthocyanins from black soybean seed coats preferentially inhibit TNF-alpha-mediated induction of VCAM-1 over ICAM-1 through the regulation of GATAs and IRF-1. J. Agric. Food Chem. 57, 7324-7330 (2009).
-
(2009)
J. Agric. Food Chem.
, vol.57
, pp. 7324-7330
-
-
Nizamutdinova, I.T.1
-
20
-
-
84880675210
-
Distinct chemokine receptor axes regulate Th9 cell trafficking to allergic and autoimmune inflammatory sites
-
Kara, E.E. et al. Distinct chemokine receptor axes regulate Th9 cell trafficking to allergic and autoimmune inflammatory sites. J. Immunol. 191, 1110-1117 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 1110-1117
-
-
Kara, E.E.1
-
21
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
-
Adachi, O. et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9, 143-150 (1998).
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
-
22
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
Burns, K. et al. MyD88, an adapter protein involved in interleukin-1 signaling. J. Biol. Chem. 273, 12203-12209 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
-
23
-
-
0027090310
-
Jr . Activation of transcription by IFN-: Tyrosine phosphorylation of a 91-kD DNA binding protein
-
Shuai, K., Schindler, C., Prezioso, V.R. & Darnell, J.E. Jr . Activation of transcription by IFN-: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 258, 1808-1812 (1992).
-
(1992)
Science
, vol.258
, pp. 1808-1812
-
-
Shuai, K.1
Schindler, C.2
Prezioso, V.R.3
Darnell, J.E.4
-
24
-
-
0346792731
-
Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity
-
Varinou, L. et al. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19, 793-802 (2003).
-
(2003)
Immunity
, vol.19
, pp. 793-802
-
-
Varinou, L.1
-
25
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J.E. Jr., Kerr, I.M. & Stark, G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421 (1994).
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
26
-
-
84860870426
-
TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia
-
Liu, A. et al. TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. J. Biol. Chem. 287, 16132-16145 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16132-16145
-
-
Liu, A.1
-
27
-
-
0032497642
-
Transgenic mouse model for skin malignant melanoma
-
Kato, M. et al. Transgenic mouse model for skin malignant melanoma. Oncogene 17, 1885-1888 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 1885-1888
-
-
Kato, M.1
-
28
-
-
10744228869
-
Spontaneous vitiligo in an animal model for human melanoma: Role of tumor-specific CD8+ T cells
-
Lengagne, R. et al. Spontaneous vitiligo in an animal model for human melanoma: role of tumor-specific CD8+ T cells. Cancer Res. 64, 1496-1501 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 1496-1501
-
-
Lengagne, R.1
-
29
-
-
77953225810
-
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
-
Eyles, J. et al. Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma. J. Clin. Invest. 120, 2030-2039 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2030-2039
-
-
Eyles, J.1
-
30
-
-
48149096869
-
IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma
-
Frederiksen, K.S. et al. IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunol. Immunother. 57, 1439-1449 (2008).
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 1439-1449
-
-
Frederiksen, K.S.1
-
31
-
-
42649134105
-
Interleukin-21: Basic biology and implications for cancer and autoimmunity
-
Spolski, R. & Leonard, W.J. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 26, 57-79 (2008).
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
32
-
-
0028077321
-
IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF- and IL-4, and is inhibited by IFN
-
Schmitt, E. et al. IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF- and IL-4, and is inhibited by IFN. J. Immunol. 153, 3989-3996 (1994).
-
(1994)
J. Immunol.
, vol.153
, pp. 3989-3996
-
-
Schmitt, E.1
-
33
-
-
0023788435
-
Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN- gene regulatory elements
-
Miyamoto, M. et al. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN- gene regulatory elements. Cell 54, 903-913 (1988).
-
(1988)
Cell
, vol.54
, pp. 903-913
-
-
Miyamoto, M.1
-
34
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
Taniguchi, T., Ogasawara, K., Takaoka, A. & Tanaka, N. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19, 623-655 (2001).
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 623-655
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
35
-
-
33748051738
-
IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda, K. & Taniguchi, T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 6, 644-658 (2006).
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
36
-
-
18744386097
-
IFN- represses IL-4 expression via IRF-1 and IRF-2
-
Elser, B. et al. IFN- represses IL-4 expression via IRF-1 and IRF-2. Immunity 17, 703-712 (2002).
-
(2002)
Immunity
, vol.17
, pp. 703-712
-
-
Elser, B.1
-
37
-
-
37349040852
-
The contribution of transcription factor IRF1 to the interferon- interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells
-
Kano, S. et al. The contribution of transcription factor IRF1 to the interferon-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells. Nat. Immunol. 9, 34-41 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 34-41
-
-
Kano, S.1
-
38
-
-
77955288962
-
Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation
-
Jäger, A. & Kuchroo, V.K. Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation. Scand. J. Immunol. 72, 173-184 (2010).
-
(2010)
Scand. J. Immunol.
, vol.72
, pp. 173-184
-
-
Jäger, A.1
Kuchroo, V.K.2
-
39
-
-
84255215452
-
Th17 cells are long lived and retain a stem cell-like molecular signature
-
Muranski, P. et al. Th17 cells are long lived and retain a stem cell-like molecular signature. Immunity 35, 972-985 (2011).
-
(2011)
Immunity
, vol.35
, pp. 972-985
-
-
Muranski, P.1
-
40
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
Okamoto, M. et al. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J. Biol. Chem. 285, 6477-6488 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6477-6488
-
-
Okamoto, M.1
-
41
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
-
Zeng, R. et al. Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. J. Exp. Med. 201, 139-148 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 139-148
-
-
Zeng, R.1
-
42
-
-
84866772544
-
Interleukin-21 has activity in patients with metastatic melanoma: A Phase II study
-
Petrella, T.M. et al. Interleukin-21 has activity in patients with metastatic melanoma: a Phase II study. J. Clin. Oncol. 30, 3396-3401 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 3396-3401
-
-
Petrella, T.M.1
-
43
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
Dudley, M.E. et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298, 850-854 (2002).
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
-
44
-
-
65249126905
-
Adoptive immunotherapy of cancer using CD4+ T cells
-
Muranski, P. & Restifo, N.P. Adoptive immunotherapy of cancer using CD4+ T cells. Curr. Opin. Immunol. 21, 200-208 (2009).
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 200-208
-
-
Muranski, P.1
Restifo, N.P.2
-
45
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
Hunder, N.N. et al. Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N. Engl. J. Med. 358, 2698-2703 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2698-2703
-
-
Hunder, N.N.1
-
46
-
-
33847362865
-
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells
-
Steenwinckel, V. et al. IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells. J. Immunol. 178, 3244-3251 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 3244-3251
-
-
Steenwinckel, V.1
-
47
-
-
1542272771
-
-
(ed. Minor, W.) Ch. 10, Unit 10 15 Wiley Online Library
-
Taylor, J., Schenck, I., Blankenberg, D. & Nekrutenko, A. in Current Protocols in Bioinformatics (ed. Minor, W.) Ch. 10, Unit 10 15 (Wiley Online Library, 2007).
-
(2007)
Current Protocols in Bioinformatics
-
-
Taylor, J.1
Schenck, I.2
Blankenberg, D.3
Nekrutenko, A.4
-
48
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform
-
Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
49
-
-
65449136284
-
TopHat: Discovering splice junctions with RNA-Seq
-
Trapnell, C., Pachter, L. & Salzberg, S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
50
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C. et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-515 (2010).
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
|