Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Singh, Sumeet Pal ^a   Janjuha, Sharan ^a,b   Hartmann, Theresa ^a   Kayisoglu, Özge ^a   Konantz, Judith ^a   Birke, Sarah ^a   Murawala, Priyanka ^a   Alfar, Ezzaldin Ahmed ^a   Murata, Kei ^a   Eugster, Anne ^a   Tsuji, Naoki ^c   Morrissey, Edward R ^d   Brand, Michael ^a   Ninov, Nikolay ^a,b,e  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c DAIICHI SANKYO CO   (Japan)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; AFIMOXIFENE; TAMOXIFEN; UROCORTIN;

CELLS AND CELL COMPONENTS; CYPRINID; EMBRYO; EMBRYONIC DEVELOPMENT; GLUCOSE; GROWTH;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL EXPANSION; CELL GROWTH; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL REGENERATION; EMBRYO; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; IN SITU HYBRIDIZATION; NONHUMAN; ORGANOGENESIS; PANCREAS ISLET BETA CELL; SINGLE CELL ANALYSIS; ZEBRA FISH; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINEAGE; CYTOLOGY; DRUG EFFECTS; EMBRYOLOGY; GENETICS; METABOLISM; NONMAMMALIAN EMBRYO; PANCREAS ISLET; PHYSIOLOGY; PROCEDURES; TRANSGENIC ANIMAL;

DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINEAGE; CELL PROLIFERATION; CYTOLOGICAL TECHNIQUES; EMBRYO, NONMAMMALIAN; GLUCOSE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; TAMOXIFEN; UROCORTINS; ZEBRAFISH;

EID: 85028705417     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00461-3     Document Type: Article

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